I wrote out a big list of my pros and cons of Wellbutrin but looks like it got blocked for some reason. To sum it up, great for quitting smoking, depression, fatigue, helped me with mood and anxiety. Had a few side effects for the first week or so but after that, pretty minimal side effects. I do still have HUGE pupils, which is not ideal. It's still worth it for me though. For ADHD, I would give it a 6/10. Definitely better than nothing. *This is my experience, not medical advice.*
@benheineАй бұрын
I can confirm, wellbutrin is helping
@DrymouthCWWАй бұрын
Interesting. I have it in my drawer and i just stopped using it because it didn't seem to do... anything. Was a little harder to pee for some reason.
@TechHug23 күн бұрын
How long did it take?
@johnnysilverhand604521 күн бұрын
I’m on the 150mg extended relief and I’m about 7 days in and I’m starting to feel….. something but definitely better? I think it takes a few weeks. From what I can tell I’m on lower dose. Hope that helps. No noticeable side effects so far far
@charlottekost999217 күн бұрын
I noticed it on the very first day. It helps me so much.
@RahulRanjan674Ай бұрын
i have been on atomoxetine for 1.5 years and followed by methylphenidate with it. It did help as I didn't have anything to compare to. Now I have switched to bupropion 150 xl (self medicating as consulting a psychiatrist isn't accessible for now. I have done fair bit of research and thank you so much for this video). this is so much better then anything with almost no side effects. I felt bad that it wasn't prescribed two years back. I doubt of having Dysthymia or Depersonalization (most likely this) with my primarily inattentive ADHD. and this has been a blessing of sorts. Atomoxeting helped me with Inattention but was no drive and methylphenidate had worse wearing off effect. this is so good and I'm going to be adding methylphenidate 10mg sr with it. PS: Im trying to online consultation with my psychiatrist.
@bgirlmidsАй бұрын
It has given me severe insomnia. I have been on it for 3 months now and I can’t take it anymore. So bad that I wanna quit it. Although on the other hand, it has helped with executive function, concentration and brain fog but at what cost? Not sleeping? I can’t. And I take it in the morning and I am taking the XL. The psychiatrist I am seeing upped my dose to 300mg from 150mg one month ago and the insomnia just got worse, coupled with agitation. It’s a nightmare. I also noticed a difference on the first day like you mentioned in the video. It was like my mind became clear.
@DrJohnKruseАй бұрын
Just to check that you're taking it all first thing in the morning. For depression Wellbutrin, even the SR form, was approved as a multi-times a day dose, even though it seems to work at least as well all in the morning. I've also seen some people just adjust the timing by an hour or so (from breakfast time to right when they wake up) and that seemed to result in big improvement in sleep at the end of the day. Some people do adjust over time, and insomnia diminishes, but it seems that you have already been very patient with this.
@Kuziela10 күн бұрын
I felt it! Yesterday was my first day! I took first pill and go to the bathroom. And after one hour I started to have ideas, and yesterday i could focus and had motivation. Started to looking for a job, I did my CV and tomorrow im going to my first job interwiev after many, mamy years of doing nothing… It is a miracle. So. Yesterday and today (day first and day second) are totally different. I though that im crazy, cause everyone tells me that I have to wait 2 weeks… but I felt it after 40 minutes! Wow wow wow! So I’m watching this film after reaserch if it is possible. It is! ❤❤❤
@JohnKruse-sh2rq7 күн бұрын
So many individual's experience matches yours, and basic neuroscience tells the same story - that bupropion should work very quickly for ADHD. Hopefully more clinicians and ADHD experts will listen to that message.
@benderbotx9 күн бұрын
I started 100mg SR today and genuinely think I noticed a difference in my ADHD symptoms already. My energy levels have been high all day; similar to having had a weak cup of coffee and I was able to stay on task at work more than usual.
@JohnKruse-sh2rq7 күн бұрын
That doesn't surprise me at all. I hope that it continues to work for you and that you find an optimal dose.
@pcie3Ай бұрын
"An *Aminoketone* not a mean old ketone" 1:07 😂
@OkAIokАй бұрын
Thank you so much Sir!
@pcie3Ай бұрын
what i find particularly interesting about this drug is the fact that its not considered a stimulant. its also a Cathinone! cathinones, aka BATH SALTS, are a family of black market stimulant drugs that were developed to circumvent the existing legislation against substituted-amphetamines.
@DrJohnKruseАй бұрын
Our definitions of what it means to be a stimulant are quite variable and inconsistent. In the broadest sense of the world, most people would agree that it has "sympathomimetic" activity - it activates the sympathetic nervous system. But I'm not even sure if we should consider methylphenidate a stimulant: kzbin.info/www/bejne/d2PcYpmljtWhmsU
@pcie3Ай бұрын
@@DrJohnKruse its quite a subjective definition. especially for an objective science. *Catecholamine **_releasing_** agents* ought to be the only drugs with the classification of stimulants based on their effect with human neurons. not how much it binds to the receptors _in vitro_
@martinrubes3044Ай бұрын
Are the metabolites active for dopamine as well as norepinephrine?
@pourcelaineАй бұрын
I went on Avulety. The SSRI activity of Avulety made it just as harmful to me as regular SSRIs. But it was interesting, I had a lot of blackout experiences, mostly when drinking (so I stopped drinking), but eventually without drinking, which is when I stopped. I bring this up because it points to the importance of paying attention to all these drug interactions! Bupropion alone continues to be the most important medication in my life.
@DrJohnKruseАй бұрын
Thanks for sharing your experience. I do have a video on Auvelity here: kzbin.info/www/bejne/kJmylnWNbdGLkJY To be a little picky about terminology, SSRI refers to "serotonin specific reuptake inhibition". While the dextromethorphan component of Auvelity has some ability to inhibit serotonin reuptake, it also has many additional neurotransmitter and transporter interactions, so pharmacologists would not label it an SSRI.
@pourcelaineАй бұрын
@@DrJohnKruse I’ll take a look, thank you! I only now realize that my comment was a little off topic, my apologies. I’ll say this about my experience with bupropion and ADHD - bupropion is capable of shutting off the “STOP DOING THE THING” signal that is normally always ringing in my head. I can suddenly exercise for longer than I could before, clean a little longer than before, read a few more paragraphs uninterrupted than before. It’s not as good at stimulants, but it helps. And you’re right about it working instantly. In fact, bupropion always works best for me the first day I go on it after an absence. My first day on it ever I ran 4 miles having not run in years 😂
@stoneneilsАй бұрын
My Concerta stopped working. It just puts me to sleep now....is it too low a dose?!?! After six good months I'm back to shlogging through work unmedicated because at least i can stay up all night again.
@Undisclosed_3Ай бұрын
I've read a bunch of experience threads on reddit and it seems like no one likes it for ADHD. That makes me a bit hesitant to try it. Isn't the cause of ED the changed muscle tone (sympathetic/parasympathetic...) by the increase in norepinephrine signaling? That should be the case with all dopamine/norepinephrine drugs, right? Why not Wellbutrin?
@DrJohnKruseАй бұрын
Reddit (or other online sharing platforms) can let you know part of the range of responses (assuming people are being candid) but don't give much information on how likely any of those responses are. And people who have bad or unusual responses are almost always highly over-represented in such forums. The older version of this video had major problems with the sound (a smoke detector went off mid-video, and I kept trying to talk through it), and KZbin doesn't let you preserve the comments when you revise/edit a video. So you missed comments from dozens and dozens of people who (mostly, but not entirely) had good responses to their ADHD symptoms from Wellbutrin. Maybe as this stays up longer, more will accumulate. But this too, is anecdotal information. It doesn't tell you the likelihood overall of getting a good, non-, or bad response to the medication, which we have to rely on scientific methods to uncover And even if we know what the overall odds are, that doesn't (yet) tell us how any particular individual is going to respond. The coordination of lots of neurotransmitter systems (particularly serotonin, along with NE and DA) is important for sexual response, and different parts of the sexual response cycle are vulnerable to different agents. None of the experts in the field pretend they know all of the factors needed for "normal" sexual functioning. Bupropion has more than a twenty year track history at helping alleviate SSRI-induced sexual effects. pubmed.ncbi.nlm.nih.gov/11894796/
@anatal6699 күн бұрын
I gona start tomorrow with the medicine 💊
@cosmosprincess20Ай бұрын
Wellbutrin for certain works. Was better than strattera but not as good as a controlled option
@TedMyrrhАй бұрын
I had brain fog with wellbutrin. I went off of it and use adderoll by itself now
@cobuck4007Ай бұрын
Thank you!
@bryangardner8525Күн бұрын
Does Wellbutrin have a drug interaction with Rhodiola?
@digaaronАй бұрын
Thanks for the insightful video. What about taking it sporadically? A day here or there? I took it some time ago and had an amazing day or two where I realized this must be what it’s like for people without ADHD. I could actually direct myself and do what I wanted to do. It was great but that effect didn’t last, even when increasing the dosage from 100mg to 200 mg per day. I’ve been off it for a while now. But what if I just took it once in a while to try to get that helpful effect? Thanks.
@DrJohnKruseАй бұрын
I've worked with some individuals who took it sporadically and were happy with the long term benefits of dosing tht way.
@digaaronАй бұрын
@@DrJohnKruse Thank you
@aleda2781Ай бұрын
Was on it for 7 days before I broke out in hives 😅
@Moon-LabsАй бұрын
I used it to try quick smoking - it made me have crazy dreams and I got really really angry- many people have 'offed' themselves using it.
@DWSP101Ай бұрын
It also made me angry too, but that’s because you’re going too fast for your dosage for me when the dosage would go up irritation, anger and agitation were expected from me and it would take about a week before that anger would start to subside, which is usually when the medication starts to somewhat hitbut yeah, it definitely has the effect of making people angry but slow dosage upping is the only way to avoid that
@stoneneilsАй бұрын
I think you meant to say 'unalived' lol....but I'm glad you didn't!!!
@processrauwill7922Ай бұрын
Does it seem reasonable to use this as sort of a middle ground between stimulants and being med-free? I’m currently trying to stop taking stimulants just for long term health concerns, but I think psychological I’ve gotten so use to doing work on them, that I feel like I need them to be fully confident in my work. Currently think about using Wellbutrin as a sort of middle ground for 6 months to a year. Something which will train me to work with less and less stimulation per se and kick that psychological dependence
@DrJohnKruseАй бұрын
I've seen people use bupropion successfully that way.
@processrauwill7922Ай бұрын
@@DrJohnKruse excellent these videos in concert with the recommendations from my doctor have been invaluable. It’s nice to know(side effects willing) I’ll have another tool in my tool box which feels safer than amphetamine.
@Spectre2434Ай бұрын
Can the Wellbutrin exacerbate co- occuring bipolar disorder
@stoneneilsАй бұрын
They all can..like borderline..this is why we're fked. I help my adhd too much..my bpd can get REALLY bad on the rebound..so i have to stay away from amphetamines. Or I'll end up killing someone lol.
@hammersaw313514 күн бұрын
It was one of the best medicines i was able to take it for many years, very mild drug overall, compared to other psychiatric medicine.
@fettoschnekАй бұрын
It doesn't work with my ADHD...I also feel brain fogy. Good Antidepressant, tho.
@madelinayahmontgomery7663Ай бұрын
Sedated me and caused me into mutism - I couldn’t hold a conversation
@shelleydee15 күн бұрын
Wellbutrin did not help my add. Too many side effects. Bad insomnia.
@JoshDTechАй бұрын
Wellbutrin weak because doctors dose to low. 450mg or go home!
@angyt1070Ай бұрын
Thank you!
@madelinayahmontgomery7663Ай бұрын
Sedated me and caused me into mutism - I couldn’t hold a conversation