THIS IS SO STRANGE. THANK YOU. Sincerely, A Biotech student
@shubham_mahi Жыл бұрын
Same Here, What kinda job You are doing now?
@martakadziolka71822 жыл бұрын
Thank you for this really educational and user-friendly lecture on the role of chaperones. I have a family member with a disorder of glycosylation (CDG-SSR4), and understanding protein transport and folding is really important to me. Your lecture is the best I have found. My family and I would be happy to see more videos on the role of chaperones - especially the TRAP complex and the BiP - in protein folding. I understand that we are only on the edge of understanding the role of the TRAP complex, but recently, new research on TRAP in the human cell has emerged (i.e. Phoomak et al. 2021). I would love to be able to better understand and visualize how the TRAP complex preserves N-glycosylation under conditions of ER stress, for example. I would be happy to send you the relevant article, which is easily available online. I look forward to watching more of your lectures!!! Happy New Year '2022
@dandanthedandan75584 жыл бұрын
This is a great video that's very easily understandable but man that mouth animation is right on the uncanny valley
@Hiyori___2 ай бұрын
Awesome video! I'm a computer science engineer, but many years ago in high school I studied biochemistry and chaperones is one topic that I remember since. The whole concept is so mind-blowing to me!
@bobby793 жыл бұрын
Bro you are a genius, you covered the whole mechanism in just 4 mins. It took me almost an hour to understand it on my own by reading book and still I was in doubt, but you made me very clear about it now.
@innate-videos3 жыл бұрын
This video is absolutely excellent - congratulations on the content, insights, clarity, and animation. It sets the standard!
@samuelfauteux67354 жыл бұрын
HSP 60 and HSP 70 are misidentified at 2:20 of the video but correct the rest of the way. thank you for these lectures they're great.
@I_DidntKnowThat2 жыл бұрын
I had to go back twice to double check.. So what are the correct forms though?
@SophiaCundiff4 жыл бұрын
Okay seriously love this so much and love how you go so into depth!!!
@silkpharmacy59044 жыл бұрын
nightmare fuel but thank you none the less
@iremasutkaloglu69684 жыл бұрын
thank you so much. Finally, I understand this subject.
@salihasaeed68173 жыл бұрын
Best lecture on chaperones💯 must say i was badly needing this type of video.
@superfantastic84814 жыл бұрын
Omg thank you for dumbing this down 😍😍😍
@omaryahia2 жыл бұрын
wow , you are really talented and doing great great job, thaks for all that effort and Quality
@saijalsood Жыл бұрын
An amazing explanation!
@roronoazoro32043 жыл бұрын
such a genius youre both in explaining the subject and that amazing animation
@dhabyaahmed81342 жыл бұрын
THAT WAS AMAZIG. THANK YOU!
@kierahurlimann4082 жыл бұрын
Very good video, explains it so well and is very helpful. The animated talking human just makes me a little uncomfortable the way his mouth moves, might be less distracting without a moving mouth 😊
@BittuKumar-ov4ei2 жыл бұрын
very very much thanku for explaining very easy way
@asmaasaad9224 жыл бұрын
thank you for your effort on this video
@zoea34744 жыл бұрын
Love how you explained it!
@salihabekh60545 жыл бұрын
Excellent!
@douglaswallace7680 Жыл бұрын
right click anywhere on the video . then click "loop" . click play . volume level very low . the best cure for insomnia !
@nikiirulan4 жыл бұрын
lol I love this animation
@kashafhamdani85832 жыл бұрын
Oh thank you thank you sir
@saragul61395 жыл бұрын
WELL DONE
@MH-bw5jj4 жыл бұрын
Perfect
@eyymma992 жыл бұрын
Holy shit, amazing work my man. Congrats
@Naikymomo Жыл бұрын
Bro this helps sooooo much
@kristenhale30225 жыл бұрын
thank you
@aakritiyadav40574 жыл бұрын
Wow😍
@nikhilverma90345 жыл бұрын
Interestingly explain...thnx
@hazossi16966 ай бұрын
Well, I know HSP60 is for polypeptide misfolded, but if I'm talking about HSP70, it's also with the same function? to misfolded polypeptides? Or is to help folding the polypeptide? I'm saying this because HSP70 take action at first moment, when the peptyde is getting out of traduction, right? Pdtt:. I'm not an English speaker, so my grammar could be bad, i'm sorry and thanks!
@noursh67834 жыл бұрын
Amazing 🙌 thank you Which program do you use to make this?
@NeuralAcademy4 жыл бұрын
Thank you!! I used Adobe Illustrator/Photoshop/After Effects/Premiere/Audition!
@noursh67834 жыл бұрын
@@NeuralAcademy brilliant! thanks
@ummulbanin98453 жыл бұрын
Thank you sir for such a lucid explanation
@marysmith37102 жыл бұрын
When this process doesn't occur properly it seems to cause catracts. Can one shed some light on how this process can be restored to help the body eliminate eye catracts with non harmful medications & with out surgery.
@sung-wookher43813 жыл бұрын
THANK YOUUU
@siddhartha73945 жыл бұрын
Cover the topic mutations in your upcoming videos..#Requestedpls#Team Neural academy 🧐😄
@NeuralAcademy5 жыл бұрын
It's on the list!! :-D Will make soon!
@zainabqureshi9178 Жыл бұрын
Hie
@milindjagtap18972 жыл бұрын
Which is best drug chaperon available in market for neurodegenerative disease
@MazharAli-yr8pe Жыл бұрын
i want to know how does prion proteins develop resistance against the proteolytic process? secondly, how does prion protein misfold in the first place?
@gabrielacastillo97244 жыл бұрын
But the hydrolysis of the ATP, do not expend energy but release energy
@slurrpyy_71502 жыл бұрын
yes but i believe this makes the hydrophobic regions hydrophilic. also it’s been two years so i hope you passes bio
@caseyandtoryshalloween12367 ай бұрын
It is crazy how a hamburger can cause these proteins to misfold
@brilliantfuture1841 Жыл бұрын
❤
@slurrpyy_71502 жыл бұрын
Pov, Cramer sent you here
@carsonneal Жыл бұрын
omg YES, cramer is the best teacher haha
@martinacoggiatti44387 ай бұрын
So… what about proteasome??
@hoobnbn___hooobnbn24539 ай бұрын
Blud says if you ENJOYED the video
@sudharshanampavankumar4992 Жыл бұрын
Hsp90 physiology
@averagejoe8839 Жыл бұрын
So all these checks and balances simply came to be unintentionally and simply throwing massive amounts of time into the equation will make such a farcical proposition more believable? The reality of this system unintentionally coalescing over billions of years is absurd as the molecules and chemicals degenerate within hours under strick labratory controlled conditions thusly leaving a time frame for unthinking matter to flop iteslf into a information packed self replicating factory within hours and immediately start replicating over and over and over perfectly. You might as well claim a space shuttle could unintentionally swirl itself together in a sand storm as this would be a much simpler and believable unintentional manifestation. what a world! The truth is right there for all to see yet some still reject reality at all cost.