Рет қаралды 43,553
This video explains coronavirus variants, mutations, PCR tests in simple terms, so that you can make more sense of media reports and the changing restrictions to our daily lives. You will also learn some cool molecular biology! The video is intended for a wide audience.
The video will cover four areas of science so you will be able to follow the facts behind the global pandemic:
• The main features of the SARS-CoV2 virus, which causes the COVID19 pandemic.
• How the main PCR test for COVID19 works, as unexpected results in these tests are linked to the rapid spread of a new variant of COVID19 in the United Kingdom.
• How mutations arise and how they can affect the behaviour of the virus.
• The two mutations found in rapidly spreading coronavirus variants that are causing concern and a new wave of strict lockdown restrictions
You can use these timestamps to jump to any section to watch it again.
1:56 The SARS-CoV2 virus, its life cycle and genome
7:37 Summary of the tests for COVID19
12:00 A description of the genetic material, DNA and RNA
17:17 How the PCR assay works
28:31 How the clinical COVID19 PCR test works
30:50 Overview of SARS-CoV2 mutations
32:06 The Central Dogma of Biology - How DNA codes for proteins
36:12 The Genetic Code
38:26 Why some mutations matter more than others
45:35 Mutations of the SARS-CoV2 spike protein
50:01 The “S dropout” in PCR tests caused by variant
This presentation is brought to you by Dr Adam West in the College of Medical Veterinary and Life Sciences at the University of Glasgow, Scotland. We hope you found this video useful. Please support us by liking the video and consider subscribing for more informative content. Feel free to ask questions or provide feedback in the comments section below. Thank you.
www.gla.ac.uk/...
/ genomicsgurus
/ genomicsgurus
Introduction video clips from Pixabay
SARSCoV2 model from Sketchfab by Annabel Slater, MRC-University of Glasgow Centre for Virus Research
Graphics © Adam West and Biorender.com