PRECISION EDITING USING CRISPR - GENE EDITING EXPLAINED!

[@StrayBerserker]

Thank you very much for the informative overview of this new technology.

[@GenomicsGurus]

You are very welcome. There is plenty more coming, including a more critical analysis of some of the latest CRISPR techniques.

[@uquantum]

Terrific presentation that clearly compares and contrasts prime editing with base editing and homology-directed repairs♥

[@GenomicsGurus]

Thank you!

[@gregsmith6756]

I'm going to have to watch the Prime editing part 10 times more to understand it. It's simple yet complicated.

[@GroovyGeek]

By far the best explainer of prime editing I have seen so far on KZbin

[@GenomicsGurus]

Thanks. Glad it helped.

[@emileachou1965]

Very good explanation. Thank you !! and hope that you make more content about crisper technology and it’s variants .

[@devotedamvs4658]

Thanks buddy! Great explanation.

[@eceeralp6251]

Thanks a lot for your effort

[@crisprtalk6963]

Wonderful. Thank you.

[@GenomicsGurus]

Thanks. Good luck with your channel!

[@sumantamohapatra6727]

Simply wow👍

[@GenomicsGurus]

Glad you enjoyed this. Great technology

[@rockinblue978]

Great explanation. Thanks!

[@GenomicsGurus]

Glad it was helpful Nigel!

[@chillaxTF]

Sorry to be pedantic, but 1:31 confused me. If a transition mutation is pyridimine pyridimine or purine purine, wouldn't it involve A G or C T? Additionally, if a transversion mutation is pyridimine purine, wouldn't it involve A T, C G, A C, or G T? Please let me know if I'm misunderstanding something here. Great video overall, thank you. You're a great teacher.

[@GenomicsGurus]

Thanks for pointing this out. You have it right of course. I mis-spoke.

[@courtneyczb]

Thank you for the clear explination :p

[@GenomicsGurus]

Glad you found it useful!

[@wazhi04]

Thanks for valuable content. It seems prime editing could do more than base editing, any case that base editing could be a better choice than prime editing? If not, why base editing is needed then? Thanks.

[@GenomicsGurus]

Base editing is more tried and tested technology. It is very efficient and improvements have been made to specificity. Prime editing is a more universal editing solution, but has been less well used in primary cells so far. Having all these options is highly valuable

[@erfan74ir]

Great talk but very low quality of the slides. Hard to read. BYW easy to follow from your excellent presentation.

[@GenomicsGurus]

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