New findings on ApoB & atherosclerosis

[@alexmacgregor8231]

I need a Paul and Peter Attia conversation so badly. That’d be lovely

[@WideAwakeHuman]

Come on - Attia is always 5yrs behind on anything new because he’s so focused on having “tons of RCTs” instead of using expertise and common sense to help decide what the truth is a decade before the official science comes out.

[@robotoguts3165]

@@WideAwakeHumanand he’s a nerd

[@geoffg9721]

@@WideAwakeHumanattia has a team dedicated only to ready studies. He’s ahead of everyone. Including saldino

[@cheesbobmcgrady]

Paul has openly tried to have a debate with him to which he has not replied nor has Rhonda Patrick, David Lustig and Layne Norton ran away from a debate with Paul based on seed oils lmao

[@geoffg9721]

@@cheesbobmcgrady everyone you named is anti seed oil. Why would they waste their time

[@nocarbsnation]

The whole LDL, ApoB, overall cholesterol issue, is SO FRUSTRATING!! I have this "debate" with my doctor every single year. Since starting this journey over 6 years ago, I am no longer T2D, no more sleep apnea, GERD/acid reflux, neuropathy, brain fog etc. I am literally a new person. With that said, my doctors freak out because I have high total cholesterol (343) and really high LDL (270), even though my A1C went from 10.1 to 5.3, my Triglycerides went from 260's to the 80's (in the 90's last blood draw). Even though I believe this animal based lifestyle has saved my life, the constant fear mongering of high LDL has me starting to second guess myself. Beyond frustrated with this topic. Actually have a CTA scheduled in March. Hopefully that will help clear this up.

[@chevelleman88]

Please update us after CTA!

[@nocarbsnation]

@@chevelleman88 will do

[@jacquidan01]

I agree, too much conflicting information.

[@RedHotChiliPeppersU2]

Any updates? I have the same frustrations as you so I’m keen to know!

[@nocarbsnation]

@@RedHotChiliPeppersU2 CTA is tomorrow morning...

[@geraldsfitnessbootcamp198]

I am a Lean Mass Hyper-Responders. My LDL 196 HDL106 Tri 32 Total testosterone 842 at almost 50 years old and I am in the best shape of my life. My metabolic biomarkers are optimal as well. I believe my results are not hurting my cardiovascular system and it is keeping me healthier. I have been practicing IF Restricted window 20 hours for over 4 years and I eat healthy fats and low carbs faithfully. I have changed my DNA expression/ epigenetics.

[@wickedah]

the answer to the question you asked at the end for me is very clear: people who are on a ketogenic diet will put more emphasis on reducing other risk factors for CVD as well so its a correlation and it doesnt disprove the causal effect between apo-B and atherosclerosis. thats it for me. love the effort and appreciate your work.

[@tlxreed]

I didn't hear much about APoB in this discussion. Given the topic is a big one in cardiac health and measurements of heart disease, I'd like to know more about Dave Feldman's stance on this and what a healthy level is for people in the animal-based dietary pattern.

[@AndreiLucaa]

+1 we need more APoB discussion

[@stewartjurgensen3357]

Mind boggling that they talk about the big difference in ldl-c between the two groups but don’t talk about the difference in apo-b levels!

[@PeaceIsJesusChrist]

@tlxreed, yes!! I’m getting blood work and am wondering if I need ApoB. I’m still confused. 😆 Dave’s company own your labs does seem to indicate that it can be a helpful doctor to evaluate as far as atherosclerosis goes.

[@TheDanielJohnsonShow]

100% Total let down that they didn't discuss this

[@tubetime39]

Before this video I was researching LDL, Apo B etc & how plaque happens and everything I ran across, including in 'OUT LIVE' by Peter Attia says it's the ApoB that causes plaque. No Plaque No ApoB. I believe the reason for this talk was to help show LMHR people that their study is showing no huge flags warning of plaque. They didn't say Not to have your Apo B tested if you are a LMHR. Surprised, but good, to see there are so many LMHR out there.

[@Sarah-ey6yy]

Lean mass hyper responder too 😎 My HDL is 76, LDL is 192, ApoB is 130, insulin is 3.2, A1C is 4.9 I'm 5'5" and 117 pound female. No medical problems at all after 2 years of carnivore diet, and before that 2 years on keto.

[@trishwest1809]

Thank you Dr Paul for presenting this exciting new research.

[@johnny7808]

props to Paul for leading off by saying "this is a unique group with high ldl but are different than most with high ldl in that they are insulin sensitive". That's the whole point. This IS NOT ldl-denying, this IS ldl-contextualizing.

[@althe]

can have high LDL with low apob, so should say high LDL and high apob (as paul did) - or better yet, just high apob. apob is the only lipid marker you need, too bad most MDs don't know much about it.

[@Lumencraft-]

Thanks Dr Saladino. When you cite a study could you please link it in the description for us. Much appreciated

[@Shakerhood69]

It's the LMHR study, l believe it will get printed in January.

[@gekekoons]

I found out about the study just after finding out that my ldl had risen 400 points after 2 years carnivore. Realizing that my bmi of 23 made my rise predictable was very important to me. Of course my medical provider freaked out, but my quality of life is so improved by my diet I won't take a statin. Thanks for covering the study, it's a very important data set.

[@antb3334]

High LDL = longer life expectancy

[@dossegundos7145]

👍🏼 out of curiosity what is your ALT or AST number .

[@ladagspa2008]

​@@antb3334 lmao. What jokers you find on this channel

[@adamsmith4982]

⁠@@ladagspa2008I believe he is referring the recent study that showed high ldl was associated with longer life in people over 70. Have you read the recent literature?

[@TheFrankHummer]

@@adamsmith4982 adamsmith, you're right about the literature. On a time basis, higher LDL reduces the risk in the elderly (I think it's for people 60 or 65 or 70 or older ) for cancer, infections, and cardiovascular disease. And there really never was any good evidence to the contrary.

[@simonnattrass2171]

Love the way Paul reframes it in such simple succinct terms in a nutshell including all the salient points to get the essence of the message across with power and force ❤❤❤

[@stewartjurgensen3357]

Except for ignoring any discussion of the actual apo-b levels for the two groups!

[@stewartjurgensen3357]

All the salient points except for the most important: discussion of the actual apo-b level difference between the groups.

[@galinagutkin8368]

But they didn’t mention if they measured apoB in those people with high ldl and if they did measured it, I’d to know apoB numbers.

[@chenatcr]

That’s exactly I am curious about.

[@MichelleAdamsPT]

Outstanding!! This has been top of my mind so great timing. Can’t wait to hear more.

[@barrons9647]

The science is the science. No twisting the facts of this study. Thank you !

[@kimberleesummurs8176]

That’s awesome, clear as day, getting the truth out there .

[@kennethh4904]

Thats a great question. If APO B causes plagues, shouldn't the lean mass hyperresponders with high LDL have more plagues than the Miami Heart study group, with low or normal LDL. Maybe, there is more to the story. Could Ancil Keys saturated fat study, be way wrong? Are statin drugs, really doing more harm than good?

[@ethanbunn1948]

I think we all know Dr. Keys study was wrong. Lots of data issues and failure to follow up on diets

[@joecanti5944]

ApoB doesn't correlate with LDL volume but instead with particle number. It doesn't cause plaques itself but can be used to infer the amount of small, dense LDL, which is useful in metabolically unhealthy people as a measure of their plaque risk, becasie they have high ApoB due to lots od small, dense LDL particles. But in healthy people eating a high fat diet, ApoB rises because total LDL rises, but it's the less atherogenic large, buoyant LDL - so the relationship to plaque generation disappears.

[@TorqueMonsterAWD]

My ApoB is 140. I've been keto/carnivore for over a decade, mild plaquing. (Familial Hypercholesterolemia) I will definitely make the decision to attenuate lipids as much as possible due to soft/hard plaque results.

[@frankd1682]

It would be interesting having Dr. Peter Attia in on this conversation. His views on LDL/ Apo B levels and its importance in determining CVD would be insightful.

[@DT-ef4nj]

There is no controversy here. ApoB was not even measured in the studies. The question repeated twice at the end - "how can apoB be causative if there's no difference in plaque between high and low cholesterol" - is nonsensical because ApoB was not even measured. People with high LDL-C can have the same ApoB as people with low LDL-C. This is called discordance. It's possible that both groups in the studies had similar ApoB (which again was not measured), and therefore had similar plaque progression measurements. When you accept that cholesterol content (LDL-C, etc) has nothing to do with plaque when controlled for ApoB, there is no confusion.

[@longevitydxtx]

Fascinating findings but need more data (bigger cohort and longer time interval). Still need evidence that other factors, aside from insulin sensitivity, won't spark plaque formation (eg. stress, inflammation, poor sleep, etc).

[@Nabeel27]

PLEASE do a discussion with Dr. Attia on this topic. Also audio is really bad in this video.

[@david_houston700]

How does Lp-PLA2 factor in if all other markers are consistent with the healthly keto group?

[@vickistonehouse2218]

at 6:47 Dave lists the biomarkers that were matched. I can't understand the one he said after blood pressure. The closed caption is HSP. I think it might be hs C-RP. Can someone clarify this lab test please?

[@R-J_Hopper]

The calcium comes from the parathyroid not getting magnesium and there for not being able to detect raising blood calcium and not releasing calcitonin. Calcitonin is also stimulated by hormones like gastrin. A study done where they supplement those two things, chelated minerals and gastrointestinal hormones would be beneficial IMHO

[@TheDanielJohnsonShow]

Why is Paul using Abop and LDL interchangeably?

[@walker.1505]

Thank you sooo much for everything you are doing Dave!👍👍👍

[@kaitlananderson4302]

Lean with high hdl, low triglycerides, high ldl, high apoB, low apo(a), high oxidized ldl, high Lp-PLA2. Can any factors besides diet be causing my high ox ldl and lp-pla2? I eat low carb animal based.

[@RNHD-se4dk]

Seed oils in your diet? Poor gut microbiome? Stress? Poor sleep?

[@kaitlananderson4302]

@@RNHD-se4dk no seed oils but the others may be occurring. So these things can affect ox ldl and lp-pla2?

[@Paulsaladinomd]

There could be many factors affecting LDL oxidation. I believe carbohydrates are important for optimal health. Some fruit juices have been shown to prevent LDL oxidation, like orange and grape juice. Low-carb diets are too stressful on the body...

[@kaitlananderson4302]

@@Paulsaladinomd thanks for your reply. I haven't found much information at all that is helpful for my situation described above. I also have history of chronic illness(lyme, mold, sibo etc) that I am still recovering from. I have been incorporating a lot more antioxidant rich fruits since getting these results. I would be very grateful if you could do a video about the different factors that can affect oxidation of ldl. Thanks again.

[@cobrakaiX]

New to this channel but i have a question about milk. If I can’t get access to raw milk should i give up milk?

[@Paulsaladinomd]

You can find high-quality raw milk near you at realmilk.com

[@cobrakaiX]

@@Paulsaladinomd I’ve used that resource. I’m in Michigan and unfortunately the nearest location is quite far. Not a sustainable option for me.

[@lindapestridge3073]

​@@Paulsaladinomd sorry dr Paul But you didn't answer the question If you can't get raw milk I live in the UK should you not drink milk.

[@GenDominion]

@@cobrakaiXshame situation here. It is really hard to find raw milk around here

[@anon1231]

Would a diet of 7,7grams of salt per day be bad? Google dosnt help bc we all know salt is good but they say otherwise

[@aakashsuriyaaakashsuriya4300]

Does freeze-drying every organ meat and consuming it directly is safe for consuming.

[@aakashsuriyaaakashsuriya4300]

Do u take any mineral supplements

[@nickleejackson09]

How can we get the results of both studies and the next progression test

[@fireprotocol]

would love to hear Attia's take on this

[@star-warsien]

Same here. Would love to see him discuss this with Paul.

[@zamfirtoth6441]

Why?

[@eduardoaugustosilvestre724]

it deserves a podcast

[@WideAwakeHuman]

Attia is too invested in all the LdL/ApoB talk to reverse his stance with one study - even if the study makes sense and is congruent with common sense. It’ll take him another 5yrs to admit it because he is too worried about RCTs instead of reality right now in front of us

[@clandestinefreedom8114]

You are the best brother

[@nhtathinfbntb2746]

i stopped processed food and seed oils last year. Only eat whole foods now. I cook with avocado oil and tallow. I also eat evoo though and certain fish. My LDL was 126 mg/dl but if you looked at me you would think I don't eat enough! I look like bruce lee...healthiest ive ever been. I honestly think if I just eat less white rice and cut back the saturated fats slightly, my LDL will even fall in the normal range.

[@PeaceIsJesusChrist]

@nht…., You don’t need your LDL to be lower. It’s actually healthy to have higher LDL. Hang around the carnivore community for a while, and you’ll come across lots of info about this! 😊

[@DK-pr9ny]

It’s a shame they didn’t measure LDL particle size in this study..

[@johnnyblackrants7625]

I really hate nutrition. I'll watch another expert say the exact opposite, and then watch this. This information environment is miserable.

[@PeaceIsJesusChrist]

@Johnny, It can definitely be very confusing! If you don’t know what to eat, at least make sure you’re eating real food, and stay away from processed foods, vegetable oils, seed oils, high fructose corn syrup, hydrogenated oil, etc. ❤

[@Roberto-cg2gr]

Hope more people can help to finance this study for another 5 years

[@GSH-vg3wf]

LDL is not causal for atherosclerosis. Based on my understanding of how atherosclerosis develops, these results are what I would expect to see. See Malcolm Kendrick’s The Clot Thickens for an explanation of the thrombogenic theory.

[@AndreiLucaa]

But APoB does cause atherosclerosis.

[@chevelleman88]

@@AndreiLucaaNot by itself.

[@chriskontos5824]

So what does cause it? And what would be the best diet for it? Especially someone who was diagnosed with familial hyper cholesterol

[@GSH-vg3wf]

@@chriskontos5824 I recommend reading Malcolm Kendrick’s book The clot thickens or his blog. For those with FH, the critical thing is whether or not you have clotting issues. There is a paper about fh and clotting. One of the authors is David Diamond. If you search for fh and clotting and david diamond you should be able to find it.

[@GSH-vg3wf]

pubmed.ncbi.nlm.nih.gov/36012410/

[@jayunit100.apache]

I think he's using the laptop mic on accident. The audio quality doesn't sound at all like a streaming quality mic.

[@simonnattrass2171]

The small amount of plaque found was accumulated over the years from pre keto days and during keto duration it has been gradually diminishing. This will be confirmed in coming years follow up studies when it will be shown to have continued to decrease. Your welcome.❤

[@disinformationworld9378]

It will eventually be acknowledged that vitamin K2 reverses plaque. Humans on grass fed meat with fat get adequate amounts. It is literally the cure for atherosclerosis. You’re welcome.

[@AndreiLucaa]

This is a completely unasked for claim. Are you prophesying?

[@sevananciaux6898]

Dr. Paul, is it healthy to eat regular meat ? I can't find anything grass fed here (only organic) and really wondered if there were hormones (estrogen f.e.) and antibiotics in regular meat. I can't find anything grass fed here in Belgium and wondered if it was better to eat regular meat every day or reduce my meat consumption because of that Thanks and keep pushing the truth to this world

[@yousufabbas1346]

Eat meat don't think about grass fed when u progress include grass fed.

[@yousufabbas1346]

Eat meat don't think about grass fed when u progress include grass fed.

[@snezanavl8580]

I though been in Belgium most would be out in green paddocks ? maybe find a local farm that sells beef instead of looking in the supermarket.

[@friederbaumann6537]

Merry Christmas 🎉

[@GenDominion]

Is my high LDL going to matter to join the military due to the carnivore diet?

[@88_AC]

Does high LDL mean high apoB? That's what Paul seems to say in the last minute

[@_carnivore_joe1520]

Someone page the Hack Dr. Alo and tell him to sit down. LOL

[@BrunoCrocco]

Lol

[@danthaman7476]

i ve been on meat and fruits for months and my Doctor says my triglyceride are way to high..... 8.3.... Is this bad?

[@dannyeichelberger7950]

this is frustrating, i eat a whole foods diet, with lots of healthy fats i.e. grass fed beef, bacon, eggs and yet my APoB is through the roof and so is my LDL cholesterol!!!

[@americoveloz]

Are you serious? Are those healthy fat for you? Why don't you investigaste about whole food plant based diet. You should lower your LDL and Total Cholesterol relatively fast, as I've done mine. Great books I could suggest to you are How not to die and Prevent and reverse heart disease.

[@Surge308]

Can you and Peter Attia debate this? I’m so confused

[@mitchmartin1871]

Absolutely brilliant information. Please keep on informing the public and docs.

[@gabrielcarrasco602]

Can someone help me out.. i wanna start giving my daughter liver or liver supplements but how much should i give her.. ,,shes 9 yrs old

[@TheGHINger]

Seems like the focus was on LDL, not apoB. Not everyone with high LDL has high apoB. Did I miss something?

[@chenatcr]

Same here. AopB is not mentioned. If their aopb number are also high, then the conclusion the made here are more convincing

[@TheGHINger]

@@chenatcr exactly 👍

[@leslieo4019]

Exactly. My LDL is 120 but my ApoB is high. My fasting insulin is 3. So am I still at risk for atherosclerosis?? I’m so confused.

[@haha-ds9dr]

Hi paul im ur new subscriber im watching your videos.i have ulcerative colitis for 2 years..i lost my weight.im skinny can I try carnivore diet? How much meat can i take?

[@devonplumley7600]

DOnt forget the meat is processed in your Small Intestine giving yoour Large Intestine a needed Rest?

[@lalad2943]

It would be interesting to know fasting blood sugars and insulin on days these people were CT scanned...

[@carlosramirez3955]

Can you do a video on clothing? And maybe some brand recommendations for men’s clothing.

[@ShoeBoyReview]

Find any good ones?

[@yogesh193001]

They didn't focus on apoB... They only look at ldl in general

[@Shakerhood69]

The group that was tested had both high Apo-B and high LDL

[@Sheena1234ization]

Hi Paul, is there a link between food and having bad dreams?

[@sealishproductions]

Yes!!!

[@darkarpit]

vitamin b1

[@blacksa-tang2488]

From my experience from the standard American diet and on carnivore. Yes. Eating sugar before bed like bread tend to give me bad dreams. But a glass of whole milk. Cream or fatty meat gives me great dreams and on top of that i feel well rested

[@franksindoneii5410]

@@darkarpitlmao!!!!

[@acousticide]

I love bad dreams... I wish I could eat something to have them... And then find out how to get sex dreams...

[@jeremygross992]

Can someone break it down braney-style for me?

[@mindscapetv1000]

This is dangerous advice. The plaque accumulation time window provided was just 1 year! Even the 10 year risk horizon that doctors talk about is too little. 1 year (or even 5) is just not enough time to make such conclusions. A 10 year follow up on plaque scores or coronary events is perhaps a better indicator. Also for a fair comparison we should also throw a population of "normal" levels of 100mg/dl or lower into the mix as well. This is like saying.. "Hey look i compared smoking 1 week vs not and there are statistically insigificant results to lung cancer correlation, hence smoking does not cause lung cancer"

[@simonnattrass2171]

Do you think you might be missing the broad point bro ?

[@firelight-vitality]

@@simonnattrass2171 Which is? Enlighten us.

[@boboallin]

The study as of almost a year ago had an average age of 52-54, average ldl of 350 mg/dl and for 4 years. 0 plaque development seen in 4 YEARS

[@mindscapetv1000]

​@@simonnattrass2171what am I missing? I thought Paul's point was that ApoB has no association with plaque buildup in the artery and I am saying that the observation for that is flawed. The time scales are way too small.

[@mindscapetv1000]

​@@boboallinNo, watch carefully, it's zero additional plaque buildup in 1 YEAR. Yes these subjects may have been with those levels of LDL for 4 years but the study does not talk about absolute plaque buildup, but incremental. We have no idea what levels of ascvd these subjects had to start with. However even 4 years is way too little time

[@peterobrien7465]

Paul can you get a calcium scan and post your results?

[@itatae10]

Lean mass hyper response people have the trend of heart disease with keto base diets due to vldl not ldl

[@sanport9642]

Please elaborate. I have very high ldl and idk what exactly could qualify me as a lean mass hyper responder but I get into ketosis without too much effort and produce high ketones.

[@jamesalles139]

should this be tagged *LMHR?*

[@madmanis12345]

I'm curious what Paul thinks of Bryan Johnson's vegan longevity diet. Dude has infinite money and a team of doctors yet chooses to go vegan for longevity.

[@jamesbrock9022]

I would also like to hear his thoughts. I know a study came out showing a lower protein diet increased longevity but I haven’t looked into that study and I think a few of the carnivore guys have debunked that study.

[@tommydinob]

@@jamesbrock9022Debunked…or refuted?

[@jfoley3484]

@@tommydinobboth it’s been debunked refuted and shown to be a special interest bullsh*t study. As all plant based ones are.

[@kanu88kanu88kanu88]

he already talked about this, he said , if bryan takes 100 + supplements a day , why doesnt he just eat beef and organ meat , he left it there .

[@madmanis12345]

@@kanu88kanu88kanu88 I actually recall the clip where he mentions that and I thought to myself it wasn't enough clarification. I agree with Paul but the whole "his diet and supplements aren't as bioavailable as meat" isn't enough of an explanation. Bryan Johnson uses his own body's biomarkers and data to prove he is reversing aging. Sustainability aside I'm curious why a man with unlimited funding and a team of doctors would opt for veganism and fasting as a means to "ideal healthy living". It's quite literally the opposite of what Paul preaches and despite what we all say Bryan is getting results.

[@mikecarter8740]

Should do a video about hormones in animals

[@powmoo]

BRO 120LDL IS SO HIGH!! You can't say that is healthy and compare it to the people with high LDL in your study. Both have very high LDL. I was eating nothing but junk food and had a total cholesterol of 136. So REALLY what this study proves is that there is a point where LDL is so high that the risk stops increasing. You are still by all the research shown from the past 100 years at increased risk for atherosclerosis. This reminds me of the egg study they did "to prove that eggs don't raise your cholesterol.". They selected people with high cholesterol so when they added eggs it didn't go up that much well I guess there is diminishing return on cholesterol investments but that doesn't mean it's healthy or okay to have elevated LDL.

[@dwaaziwaazi]

How could this doctor never have a CTA test?!

[@ItsmeStaygoldkid]

I eat 3 bananas a day. All the anti carb people are freaking out right now lol

[@SimplyHuman186]

Omg omg omg. Lol yeah that will prevent ketosis. Every human being is born in ketosis. Bananas would prolly kill a baby.

[@ItsmeStaygoldkid]

@johnrecker nope. I was 278lbs now at 157lbs 16% body fat eating 3,000 calories and 300 Carbs. Oh, and my blood work is perfect.

[@diegodesouza9697]

@@ItsmeStaygoldkid don’t need to worry about if you are eating real food. But not eating carbs you feel better.

[@ItsmeStaygoldkid]

@@diegodesouza9697 I eat nothing but real Whole Foods. All my sugar and carbs come from real food.

[@multitablez7825]

i think it depends on the carb. it is hard to find quality ORGANIC carbs. when you do, they are good for me. rice and noodle's, extremely rare to find @@diegodesouza9697

[@aidanmays7825]

Ive been following your advice and feel amazing, lost a lot of weight, health problems disappeared, etc. But you dont look healthy in this clip. You okay dude? Edit: just the red eyes. Could be light

[@matthewpolishing7294]

I disagree Paul I don't think you should eat unless your hungry I noticed I'm not hungry at all so I'm not eating I need fasting

[@Elvin6669]

Paul, why do you care? You are not even on a ketogenic diet.

[@Sandeepkumarj-fb3fz]

Love from india❤

[@ericoshea9382]

Teenagers who need cholesterol the most have LDL generally between 25-60. Problem is that most people will not know whether LDL will cause ASCVD until it is too latte or significant damage has been caused- safer to have lower LDL since it does not cause harm and no benefit from high LDL has been articulated. I want these recent studies to be the most predictive but health is too important to ignore the overwhelming studies showing a direct correlation between LDL and ASCVD.

[@joshlockie9285]

Going down with the ship I see.

[@JMK-vo8pv]

You nailed it, josh! It is amazing that that the great majority of Americans, including our PCP's, STILL believe that LDL particles, with their cholesterol "cargo" actually CAUSE ASCVD. I believe that our PCP's and cardiologists have been bamboozling us patients for decades by telling us to get that LDL-C as low as possible while TOTALLY ignoring the root cause of atherosclerosis-high blood glucose, high blood insulin and the accompanying high TRIG/HDL ratio.@@joshlockie9285

[@HarryLlewellyn27]

Some poeple don’t choose to be on a ketogenic diet. This can be due to food sensitivities, epilepsy, auto-immune, IBS and many other reasons. It’s for those poeple who want to see whether or not there ketogenic LDL is safe, which clearly it is. But what it also does is creates questions regarding ASCVD formation. They are not saying it’s the perfect way to be. They’re saying it might be completely fine to have high LDL with these circumstances (being a LMHR)

[@ericoshea9382]

@@HarryLlewellyn27 agreed. I was paleo and keto for the past ten years but switched to a Mediterranean diet to reduce saturated fat intake. Elimination diet like carnivore and keto definitely have lots of positives in terms of inflammation, weight loss, etc.

[@jw4792]

@@HarryLlewellyn27you don’t have to resort to ketogenic or even carnivore for said issues. Said issues are related to instances of leaky gut, which can cause antibodies to be formed to certain foods, thus some having a complete allergic reaction and others being sensitivity reactions. Can easily get blood tests done for leaky gut, food allergies and sensitivities, and can adjust your foods accordingly until the leaky gut is healed and immune response to said foods goes away.

[@EssentialMattersPodcast]

lets get Peter Attia on here to discuss this...

[@Kjuken69]

Why?

[@EssentialMattersPodcast]

because Peter Attia does tons of work with ApoB and astherosclerosis@@Kjuken69

[@LawrenceAugust_]

Paul's aged a lot in the past 3 years. 😳

[@PeaceIsJesusChrist]

He is 46 and looks fantastic!

[@momplaysdarksouls8273]

Nice YT plat 🤩

[@DaveOriginallyfromBrooklyn]

What is he eating this week? Carnivore? Fruit? Honey? Pizza?

[@Likesforhire]

Just eat more carbs. Eat a balanced of Whole Foods. The “5 ingredient rule” will keep your ldl and everything else regulated. SMH.

[@johnhanson67]

Wow, you're taking the fast train huh? You sound like a carb addict...in denial.

[@26mook]

Name the cells in your body that can handle fructose ?

[@hoon_sol]

@@26mook: _«Unlike glucose, fructose is not an insulin secretagogue, and can in fact lower circulating insulin. _*_In addition to liver, fructose is metabolized in intestine, testis, kidney, skeletal muscle, fat tissue and brain,_*_ but it is not transported into cells via insulin-sensitive pathways (insulin regulated transporters GLUT1 and GLUT4). Instead fructose is taken in by GLUT5. Fructose in muscles and adipose tissue is phosphorylated by hexokinase.»_ It has in fact been known that feeding fructose to diabetics, either in the form of sucrose or just fructose itself, greatly contributes to improving their glucose metabolism and brings their blood sugar levels down, curing their diabetes over time. We and our ancestor species have literally derived as much as 80-90% of our daily caloric intake from sugar for 99.9% of the past tens of millions of years, and roughly half of that sugar has been fructose. The idea that "muh fructose bad!!" is such hilariously stupid nonsense that's it's hard to tell why morons keep parroting it.

[@Likesforhire]

@@26mook lol who cares lol. I’m a very active person who works out all the time. Plus cardio I’m healthy person with 17% body fat just by eating Whole Foods. Stop spreading your weird tribalism agendas. Sorry I eat carbs and thriving lol SMH.

[@26mook]

So you were so eager to write that you forgot my simple question ... In the near future Nicholas Norwitz, PhD from Oxford, 3 year MD student Harvard, will show that 12 oreos a day is more effective in lowering ldl compared to Statins ... so junk food to lower ldl ... just like carbs !

[@Nieves_mly]

👍

[@kalfried]

Is the take away from this study that people on a ketogenic diet X4 years with high LDL have the same plaque burden as age matched controls on the SAD? Not sure that's exactly a mic drop moment.

[@stevedow9076]

Three times LDL level, no difference in plaque buildup. High LDL not cause plaque buildup. Mic Drop 🎤

[@multitablez7825]

did paul get his teeth changed? i think they stand out more and look more fake. his old teeth looked better

[@georgekolton9059]

😅

[@simbajonsky550]

Feldman strikes me as low T & high lp little a

[@jzadomaaa-xn8hz]

This guy made a name off sv3rige videos and ideas😂

[@johnhanson67]

Dumbest comparison ever, carry on fool.

[@helloman5576]

You mean that psychopath? Get outta here man

[@pr1712]

Why he call himself diet DOCTOR while his not doctor, that is misleading and wrong.

[@Lopata991]

This guy is looking way worse than 2 years ago. Like a deranged child that rebeled when his mom told him to eat his veggies. Can't wait to see how this progresses further.

[@integralsun]

I like Paul’s passion and his interviews but he does seem to be aging noticeably….probably genetics though not carnivore.