How to extract chemicals from over the counter products

[@eloquentia7207]

A part of the final exam for an organic chemistry lab course was to follow a synthetic procedure to get a product. They did it in pairs. So a couple of students got to prepare acetylsalicylic acid (aspirin). At the end they were supposed to get crystals but instead they were left with some wierd yellow oil with no chance to crystallize. They were sure they had failed the test. Until one of them remembered he had a pack of aspirin pills in his backpack. Bingo! They quickly crushed them, extracted with chloroform, and recrystallized to get really nice crystals. So the prof came and examined the product. He asked them many questions about the procedure, reaction conditions etc. At the end he scratched his head and said: "You know, every year we get this wierd yellow oil, but you guys were the first to get crystals!"

[@spiderman1579]

How did every year all get yellow oil? The specific extraction for the test what different from what they quickly did last minute?

[@eloquentia7207]

@@spiderman1579 I guess that the procedure they gave students year after year was not very reliable and did not lead to the desired product, but the profs were too lazy to look for another one and didn't care. On the other hand, commercial aspirin does, of course, contain a lot of aspirin, so the students were able to recrystallize it.

[@spiderman1579]

@@eloquentia7207 right but they must have used a different method then the exam no?

[@eloquentia7207]

@@spiderman1579 one of them had aspirin pills in his bag by chance, so they had access to their final product in great amount and high purity. They discarded the yellow oil and continued working with the pills.

[@Lambda_Ovine]

Aspirin has aspirin. Can I have my PhD in chemistry now please?

[@amscientific6]

As a wastewater treatment technician, Nile Red's Videos keeps my mind fresh and with ideas!

[@Adri_drinks_wtr2]

U be extracting shit from shit water ?

[@j0hnny_R3db34rd]

@@Adri_drinks_wtr2 No he be extracting water from shit and making shit drinkable.

[@cboy-ou2hr]

Aye my very first job I hated the hell out of that job I don’t miss those days 😂🤢🤮

[@yusefsadik8730]

@@cboy-ou2hr the smell of hydrogen sulfide hits different🤣

[@Oroborospaces]

We all know why were here

[@mlwiz950]

This is the realest comment I've ever seen on KZbin

[@dimentbarg9793]

I don't tbh

[@Oroborospaces]

@@dimentbarg9793 drugs

[@chaseramos4865]

Why?

[@chaseramos4865]

@@Oroborospaces what are pa drugs

[@romulusnr]

I think it would have actually been interesting to see the video of the failed lidocaine extraction, to see what can happen and the creative thinking that goes with trying to solve unexpected issues.

[@peterdevaux4394]

.

[@christopherbarnard9672]

​@@peterdevaux4394😂🎉I honestly don't wor😊

[@j0hnny_R3db34rd]

But that never happens.

[@ghguyrur7]

I’m here for chemistry, I really like it and am getting into it (SAFTY and SLOWLY) I searched something and found myself here. I was really happy to hear your voice. I didn’t even realize it was your channel when I clicked :)

[@hl_crowbar]

I extracted caffeine from coffee and tea as a high school graduation project and it took me a lot of trial and error. This video came out a year after I graduated high school. I used dichloromethane to dissolve caffeine and since it volatile I basically waited until it evaporated and weighed the caffeine. The experiment was a mess and I learned a lot which is probably not a good idea when it's such an important project lol. Thank you for the video I've been dreaming of recreating it properly.

[@OmniversalInsect]

You had access to DCM in high school?

[@PunTimesWithNeil]

Nile red must be on several watchlists by now

[@fabianmuller5946]

Thank you for all the work you're doing, I find every video of yours extremely entertaining and informative. Keep up the great work! I have one question: Where do you generally find all the instructions for the synthes you do? I've tried googling some of the work you've done, but couldnt find any PDFs or anything alike. Would be happy to get a response.

[@NileRed]

+Fabian Müller It really really depends on what it is. I love it when I can find a PDF that students use for labs, but often that isn't the case. Depending on what it is, it is usually a mix of using Scifinder (paper search engine), reading forums like ScienceMadness, googling, searching google books, and using my own knowledge. I am going to try to post my sources better in the future.

[@thespecialduck5030]

@@NileRed lol i can hear him say what he typed

[@takusaka3667]

@@thespecialduck5030 lol, me too.

[@nilnileer]

Same lol​@@thespecialduck5030

[@leandroemmanuelalvarez6439]

To take out the color from the pills, you have to add some activated carbon and reach boiling point a few times. Filter it off while hot with a bed of celite and get rid of the activated carbon.

[@benJAMIN536]

This is a great video detailing extraction methods that goes over some important stuff, thanks for posting it.

[@NileRed]

+benJAMIN536 I am glad you enjoyed it!

[@yellowgoose5043]

@@NileRed nilered, let's hope you never get taken down by the "great" communist KZbin. :) You are an amazing person and keep it up man, even tho I'm replying to an old comment idc. Lol

[@supersophisticated9943]

@@yellowgoose5043 If KZbin is communist then I'm a frog stuck in a tall tower. /m

[@VirtanenDK]

@Super Sophisticated He's a flat-earth believer to lol. KZbin is 100%, not Communist. Google is such a greedy company. Just the earnings of KZbin, are huge. Some people are getting strikes all the time, or have huge problems with the algorithm. Some have lost their channel to hackers, and KZbin has resolved nothing. I like to watch KZbin videos. I feel I am paying for the content (but not to the right people). I sit through bad commercials, Google has probably sold my addi, many times over. Today i use a VPN, wonder why, i didn't do that before. Sorry for the long comment, but i don't like the way KZbin is doing things.

[@黄蟮]

​@@NileRedBro, have you ever made oxytocin? I'm very curious about this. How is it extracted from the ergot fungus? I really want to extract it myself. Can you teach me?

[@ska2ol]

I love your videos so much! they make me motivated to do chemistry

[@mrchangcooler]

My day instantly gets better when I see a new Nile Red video. Also, do you think it's possible you could synthesize Menthol?

[@NileRed]

+Mr.chang cooler I appreciate the love! I have actually been looking into menthol. I think the synth is a little out of my ability for now though in terms of equipment and reagents.

[@mrchangcooler]

Nile Red That's too bad. And no problem, your videos are always fantastic.

[@theCodyReeder]

+Mr.chang cooler I guess I could give it a shot.

[@mrchangcooler]

***** I'd love to see the both of you give it a shot at some point. If you do give it a shot and you don't end up making a video on it, tell me how it went.

[@alphamalewolf2616]

+Cody'sLab didn't think i'd see you here either. xD how coincidental.

[@SkynetT800]

I'm impressed by your knowledge. So far you've taught me how to make acetone ,ethanol more. Thanks👍

[@gagemal5]

To be completely fair ethanol is like one of the simplest compounds to make it’s dicarbon primary alcohol, wait till you find out about 6 member ring secondary alcohols with two delocalized electrons clouds spinning in circles above and below the alcohol ring… ☠️☠️☠️ shit gets crazy real quick. For reference I’m talking about phenol (an altered benzene), another interesting chemical to look at the molecular orbital model is ferrocene(it’s an iron benzene sandwhich)

[@WildBearFoot]

I once ordered an iron benzene sandwich at Subway, they even added extra pickles.

[@CaptivaLP]

Note: when you got tensides you should always try breaking the emulsion (if it is one) or check for a helper substance which is in a tablet that can act as Emulgator. It’s important to remove Tensides first to avoid a low extraction rate

[@saksezo]

I've been looking for this since I first discovered psychedelics.

[@FreakinKatGaming]

You are smarter then you need to be little one. Why not go enjoy life and wait a little before you go down that road.

[@Septiviumexe]

I agree, good for a monthly fix, but dont get too attached. Your brain is too valuable

[@krisraps]

Sak Sezo, Domn`t listen to these people, do what you wnat to do and don`t listen nobody. JUST DO IT! Make extract codeine, morphine, methadone out of everything, do it, use it, but be cerafuklll, they are some hell of a drug

[@krisraps]

Agree

[@Lrofmaulol]

TheStonedGamer 420 'I'm 16... My PTSD' Right. Fucking millenials.

[@StudyWithNika]

this guy makes the best chemical videos on KZbin

[@loopyawesome2239]

Dear FBI, BATFE and DEA, I'm just having a binge of watching about extraction and drilling lowers simply because I'm bored and tired. Please don't break into my house.

[@BallBagDonnie]

How did you separate the povidone from the caffeine? They share the same solvents. Does the povidone have a lower boiling/evap temp and so was evaporated with the alcohol/water?

[@vanderburg.M]

This is one of the most brilliant chemistry videos I've come across.

[@hypnosstratagem1277]

Great video with an intriguing method. As a home chemist, I will certainly be trying this method.

[@buknolan]

I love this channel. Thanks for being you, Nile Red.

[@wanshei]

I will definitely be a patron soon. My neighbor had a thing for me and asked me one day "is there anything you don't know?" I did a quick inventory. Celestial mechanics, electronics and chemistry." So I took a summer coarse on astronomy at a local Community college, built my own telescope and could point out most of the constellations for the average lay person. I'm no Michio Kaku. I've been an auto/truck mechanic for over 15 years so I actually did know enough electronics to fix my car and I was an (real) electricians helper so I can do any home repair project all that's left is CHEMISTRY!!!! Bwahh ha ha haaaaa

[@Reds_kickin_ass]

cool story bro

[@yahoomotherfkr5020]

A whole year and the guy now works for space x

[@tryphonunzouave8384]

What's the point of this comment ? Why did you only list three things, do you know a lot about like... What proteins does a pigeon need in order to grow properly ? I guess not, nobody does, this is a shit example, fuck me

[@Suitswonderland]

I was pretty fed up with lactose in my medication so I started to extract the Temazepam and it forms such lovely crystals after an ethanol or methanol extraction but I feel like it kills the potency, perhaps during the drying stage in which I left it covered with some paper towel overnight for all of the solvent to evaporate so I never really continued doing so but the crystals which form are very beautiful and there is something about having crystals of Temazepam which made me a little giddy inside.

[@randykitchleburger2780]

Sounds fun

[@Beau1990]

Could you not just cold wash valium and filter it through coffee filters the same way you can will Forte's. Also can tapentadol be purified through the same methods,? Any input appreciated.

[@Zachmartus]

man I supper when you had 3k subs now almost 20k! congrads!

[@NileRed]

+Zachmartus You are one of the originals! :)

[@alanraza2570]

NileRed now you have over a million subscribers wow

[@progod6017]

@@alanraza2570 3 mill

[@Lostpanda123]

I respect you because you are sharing knowledge. That's it! :)

[@jayyyzeee6409]

If my chemistry teachers had been even 1/10th as inspiring as your videos, I would have been much more interested in chemistry. I got As and learned everything they taught me, but never really cared about the possibilities. The worst chemistry teacher I had would just come in, write the text word-for-word from the textbook on the whiteboard as he spoke it, then he would call it a day. I remember labs where we collected data, messed something up, then did some creative math to work backwards to get to the desired result. I also remember splashing some pretty strong acid on my shirt and being embarrassed, I hid it and completed the lab while my shirt slowly dissolved. Those were the good old days!

[@Velemir374]

Amazing video, thank you :) As a side note, in tablets you can pretty much ignore everything except carbohydrates (such as lactose, starch, maltose, dextrose, cellulose etc.) other components (sometimes including active component) are present in very low concentrations, rarely more than 1%.

[@NileRed]

+Veo That is true, I should have actually mentioned that.

[@akafume]

i feel safer knowing nile is teaching

[@odee9007]

I've always been wondering how to do this stuff myself! thanks!:)

[@DejaStacy]

I got my stuff delivered discreetly by this mycologist whose get lsd, dmt, mushrooms and more

[@DejaStacy]

Dude is on telegram and Instagram

[@DejaStacy]

@pham_smart1

[@clarencek3658]

Man this channel is so awesome

[@NileRed]

+Clarence Keaton Thanks!

[@techgamer1597]

Please be a chemistry teacher if you're not already. You are amazing at explaining things.

[@messiahyah]

Nice job on the video I find it quite helpful! Have a great one!

[@mickeysquintz9650]

Clandestine chemistry. I FUCKIN LOVE IT.

[@sinda1635]

I got my stuff delivered discreetly by this mycologist whose get lsd, dmt, mushrooms and more

[@sinda1635]

Dude is on telegram and Instagram

[@sinda1635]

@pham_smart1

[@superhard6606]

In east Europe almost every single teenager is a Chemist 🧑‍🔬 We love spending our days and nights in the kitchen, making our parents proud 😊

[@cantho11]

Thanks I will used this for prepping, turning spoil food into good food.

[@theagency13]

You're awesome! I am enamored with chemistry because of your videos. I wish you were my chemistry teacher in high school.

[@ThePaulPyro]

Brilliant video! These are some very useful tips! I have a couple questions: 1.) What camera do you use? 2.) Why is your youtube channel so awesome? Cheers from Canada.

[@NileRed]

1) canon 6D with the beautiful 24mm f2.8 lens. 2) thanks! :). I do my best

[@ThePaulPyro]

+Nile Red Spectacular quality, bravo! (I use my phone camera for my videos, works alright but some issues every once and a while.) And it is evident in your videos, you explain everything thoroughly. Proud subscriber :D

[@NileRed]

Thanks!

[@astbrnrd]

Hummm....so extracting lido hydrochloride IS A DIFFICULT task.... Or just out of that product you had at hand?? Interested in the science behind it to see if from 400ml of 4% lido HCL could be extracted from the bottles (50ml/40mg ea) to make at least 60-100ml of 10% lido HCL (hope that made sense). Second the awesome Chanel comment ;-)

[@NileRed]

I might in the future, but the yield just isn't amazing. And considering iodine isn't super hard to get off the internet, it is hard to justify a whole process. However, I might do it just as a matter of interest!

[@ashleymaethompson449]

As usual you are more than amazing thank you

[@braekbeat000]

...a spreadsheet. Good idea. Sweet vintage Visionware.

[@orionion]

Some of these over-the-counter extractions are surprisingly simple. For most dextromethorphan-hydrobromide products, all you need is baking soda, purified benzene and Vitamin C in an easily water-soluble form. A kitchen will do for a lab, since you're likely to find everything you need there.

[@onixtv4034]

I came here to learn how to extract pseudoephedrine from cold medicine.

[@amkamomega]

*Happy Jesse noises*

[@i-use-arch-btw3954]

Now you just need some red phosphorus.

[@1ericcarter]

Muriatic acid

[@heezywrld]

just get pseudoephedrine tablets bruh

[@crf80fdarkdays]

@@heezywrld can't do that in Australia bruh..

[@joeestes8114]

keep the video's comming, i really enjoy watching them.thanks !

[@ItsAnonymousGuy]

Sorry for my ignorance but, exactly, what separates the povidone from the caffeine if they are diluted together? If you evaporate the dcm, supposedly you get not only caffeine but also povidone in the final results right?

[@shansra11]

When you recrystallize the caffeine and povidone, you slowly lower the temperature so that the caffeine gets less soluble and precipitates out. The povidone doesnt precipitate out because there is not that much of it so it is more soluble.

[@MaachoMaan]

The povidone is used specifically to inhibit recrystallization, so I'm not thinkin' this works!

[@KowboyUSA]

Videos like this were why I subbed.

[@Shodkev]

Please excuse my ignorance, but if the povidone is also soluble in dcm, what stops it from recrystalizing out alongside the caffeine?

[@chrish.942]

incredibly late answer, it comes out alongside the caffeine after the DCM extraction, but it stays in solution after recrystallisation because it is soluble in cold water, unlike caffeine, which precipitates as it cools down

[@hondo190]

@@chrish.942 late, but exactly what I wanted to know. So ty

[@leandroemmanuelalvarez6439]

@@chrish.942 also he forgot to take out the color with activated carbon and filter it off with celite

[@steveanderson971]

You should look into an Acid/base extraction. Much better but takes a little more chemical knowledge

[@travissmith5037]

Could you recommend what to use taking out naloxone from burp in suboxone ..that shot is unhealthy it does exact opposite of the claims...and docs hands are tied to wrote subutex it is formed without added killer naloxone nothing locks onmnmm

[@blackfordoblique1965]

Summarily: Nilered is one of the best

[@victorunbea8451]

Thanks. I was searching for this to learn how to extract phenylephrine from cold medicine. In my country you can only find it OTC combined with acetaminophen . I can stand the pain, fever and headaches during colds but the stuffy nose kills me and I've abused nasal sprays too much...

[@andrewmichaels6298]

Hahahahahahaja phenylephrine isn't a good "precursor" for your cold... stick to pseudo

[@timwheeler1503]

@@andrewmichaels6298 🤣🤣🤣

[@coolfiretire12]

hahajahahajhajahajajajajahajahahahahahhahjahaja owned by andrew michaels (i dont know anything about chemistry)

[@WeighedWilson]

Try green chile. The hotter the better to clear sinuses. Eat it, don't inhale it.

[@SuperWarrior-zp6eg]

Thanks very much 4 this, NileRed

[@JeffandJake]

Excellent video as always. I plan on synthesizing caffeine from uracil in the lab later this week. I have also heard of it being synthesized from theobromine, though I do not have access to that reagent so I've decided upon the uracil method. Any plans to do a caffeine synthesis video, rather than extraction? Cheers from Ontario.

[@NileRed]

Actually I do plan to make it from theobromine. It should be pretty easy to do. I was going to try to extract theorbromine from cocoa and make caffeine. But I don't know if its possible to get a clean extraction. Otherwise I can buy theobromine and synthesize it. Going from uracil is also an interesting method.

[@JeffandJake]

If you have a chance, I recommend checking out the protocol available online for the uracil method. It's a far newer procedure compared to the theobromine method, and yields seem to be in the mid 80s which is definitely more promising than the comparatively low yield from theobromine. Either way, looking forward to your video on caffeine synthesis.

[@NileRed]

The theobromine method has the advantage of being like one step. I just found that uracil can be made from maleic acid and urea, very interesting. This could be a nice ground up synthesis. Is there an easy OTC source of maleic acid/anhydride?

[@JeffandJake]

+Nile Red As far as I know, maleic anhydride/acid is used in fuels and plastic polymers, so I imagine the extraction would be fairly complex as there's a huge number of interacting molecules in there. I know that you can produce maleic anhydride through oxidation of benzene or butane, check out "A study of the catalytic oxidation of benzene to maleic anhydride" by Basil Dmuchovsky et al. Urea is obviously available readily through your lab's supply chain or can be extracted from urine (though I don't know if that would make for a good video...). Do you not have access to uracil? It's fairly inexpensive at around $0.80/g CAD, not sure if you've got it in stock though. I'm in the process of acquiring equipment to perform the synthesis, I work in a molecular bio lab so I'll be borrowing some glassware that we haven't got on hand. Also, looking forward to your luminol video, we use that reagent quite often in lab.

[@NileRed]

Cool thanks for the info. I am getting my urea from instant cold packs (i do have reagent grade urea though). Let me know how your synthesis goes! I am very interested.

[@andrewfields9987]

Hey Nile Red, where do you get the procedures and steps and general ideas for videos from? Any online sources? I'm curious because I'd like to start doing some more types of this work in my lab (as opposed to class "kitchen" chemistry). Thanks!

[@NileRed]

I get them from papers, forums and other procedures. Some are just made up by me. It really depends on what I do.

[@andrewfields9987]

Would it be possible for you to link some of those forums or papers? It's cool if you don't, just wondering!

[@NileRed]

Off the top of my head, I can't think of many. I am looking to do this eventually though: www.sciencemadness.org/whisper/viewthread.php?tid=13130 The papers I will link when it is relevant to the video, but I dont have the links on me. You also wont be able to read the paper unless you have some sort of paid access to it.

[@JeffarryLounder]

I'm so confused. How would recrystallising the caffeine purify it? I thought the povidone was still in the solution with it. Wouldn't it just recrystallise both the povidone and the caffeine?

[@babihute97]

Hi, i'm try to answer ur question about understanding the recrystallization. From the chart given, you can see that the povidon and caffeine both soluble in water, BUT, in cold water the solubility of caffeine drop to 2g/100ml, meaning, if both the pv and cf is soluble in hot water ,when the temperature goes down its suppose to retain the pv inside the water while the cf solubility decrease and recrystallised. therefore, pv fully dissolved in ther water while cf recrystallised and filter off. yield lost of caffeine is because after each recrystallization there are still some caffeine will dissolve in the water. Any recrystallization step will lead to a lost

[@macon8638]

@@babihute97 cheers

[@RobPoppy]

Sublimation is so much easier and much higher % yield…but either way…you can’t use it for anything. It would explode a horses heart so you’d be toast.

[@samuelalbritton2224]

It is so cool though how you are thinking. It has really opened my eyes to seeing all the chemicals that are in our everyday products we use. Anyone know a good channel with a chemistry background guy teaching you how to make safer alternatives to things like soap deodorant detergents and everyday products. Would like to rid the use of toxic products

[@CC-bp2hn]

Hey. Love the chemistry videos, been marathoning them recently. Any chance you could do a video on how to recrystallize various substances (in the generality that you did in this video)?

[@SoCalgardener]

Any luck lol

[@motiv311]

end up with an HCL form of whateer you want, and then air dry it in a pyrex pan

[@tyfeelgood]

I’m glad I found this channel 👌

[@SailingSarah]

You should make a video on how to clean all the garbage and poisons out of our prescription medications. Everyone needs to know this life saving knowledge

[@leslieanne447]

You can usually figure of what in nature is being mimicked and go from there. Natural plants and herbs for one example cannot be patented. It's easier to start with that and go the other way..Tinctures and extracts etc.

[@LemonChieff]

Are you making fake cocaine ? I mean cafeine and lidocaine… ._.

[@GabrielDipo]

Hmmmm

[@kelvinzenteno3945]

What's other anesthetic stimulant would he be making?

[@lorexcold]

@@kelvinzenteno3945 amphetamien

[@potatomanure3773]

@@lorexcold amphetamine isnt an anesthetic

[@aidanirelan9423]

Potatomanure it’s not, but lidocaine is

[@dutstinroach]

how about an extraction of Dimethyltryptamine

[@xxxSolidShrimpxxx]

+dutstinroach i lol'd

[@rangerfox532]

+dutstinroach Mimosa Hostilis works great and is fairly easy to get. I would love to see him extract it also, I have in the past but couldn't get a good yield do to lack of equipment

[@dutstinroach]

+killer rgm yeah I tried an extraction once using acacia confusia but like you did not get much and what I did get was oxidized and not very potent

[@TetraSamurai]

Good luck, near impossible to produce pure dmt unless you have university level knowledge in chemistry

[@Domenic367]

he said Dimethyltryptamine not Dextromethorphan.

[@zock4419]

Very nice to see that you have thought about my acetone dry distillation idea :)

[@NileRed]

It's a good idea. So I'll try it out!

[@harrybrammer4786]

how did he get rid of the povidone as it was soluble in the same things as caffeine

[@francisnaveen9041]

He recrystallised it from water. Only caffeine is soluble in hot water while providone is not.

[@bilbobaginutopi2284]

how do you properly dispose of DCM at your house?

[@supersophisticated9943]

This is a super helpful video! Now we can-

[@DejaStacy]

I got my stuff delivered discreetly by this mycologist whose get lsd, dmt, mushrooms and more

[@DejaStacy]

Dude is on telegram and Instagram

[@DejaStacy]

@pham_smart1

[@andywells8125]

This would make a great undergraduate guided discovery lab!

[@alokinwhiiz427]

Could you do a video about extracting alkaloids from plants (ex. Datura)?

[@kilian8250]

It’s the same idea

[@Killavilz]

Im subscribing from an 9y. old video in -24. Big up!

[@batenkait0s657]

but what do you do if you cannot find solubility data for what you are extracting? (for example certain cellulases) do you just try random solvents and use the extract on cellulose until you see which one breaks down cellulose and use that to determine which solution had the enzyme dissolved in it? or would you just extract everything else until only that remains? also is there one easy way to determine a chemicals solubility or is that impossible due to stearic forces ect?

[@teknofreak2387]

Cellulose ethers are used to make gel with water, so try to extract it with organic solvents before adding water

[@DonCarlos590]

Dayum. ive been looking for this information.

[@rustyleeshackelford6283]

Welcome to the watchlist

[@cowdough94]

I can watch anything I want. I'm American. knowledge is powder.... power

[@buddyhart380]

3:30 Washing with water to get rid of the water soluble stuff- wouldn’t that get rid of the caffeine as well?

[@johnladuke6475]

I love watching a Canadian chemist make videos. Shopper's Drug Mart? I know just where to find these ingredients!

[@DejaStacy]

I got my stuff delivered discreetly by this mycologist whose get lsd, dmt, mushrooms and more

[@DejaStacy]

Dude is on telegram and Instagram

[@DejaStacy]

@pham_smart1

[@cool_dude1988]

amazing video, very well done

[@mrjackie-yx4bi]

Could you please tell me how we extract Latex from cocaine?

[@vadaza]

I got my stuff delivered discreetly by this mycologist whose get lsd, dmt, mushrooms and more

[@vadaza]

Dude is on telegram and Instagram

[@vadaza]

@pham_smart1

[@coleflynn7538]

uncle escobar gave me a plastic chair...

[@Haagsebluf]

This comment is underrated ;P cheers

[@10bokaj]

learning to think for yourself is awesome

[@HamzaElkhatib]

I know this is a late comment, but what if there are "natural/artificial flavours" as a listed ingredient?

[@jameswalsh5733]

You can usually find a good list of Ingredients with a googling

[@randalljames730]

How do you separate the povidone from the caffeine???

[@blanz4202]

Awesome video, chemistry is amazing. You should make a video extracting MDMA/MDA from ecstasy tablets! That'd be super dopee.

[@TetraSamurai]

MDMA is ecstasy, no idea why people think ecstasy is a combination of different drugs.

[@Reds_kickin_ass]

you have no idea wtf youre saying dude dont do drugs keep watching you tube buddy

[@GogiRegion]

(+BaldManLogan) You really don’t know how the black market works, do you? Ecstasy is classically MDMA, but tends to have multiple things in it. Oftentimes meth is a main ingredient because with no tolerance, it has near identical effects orally (there have been studies on it for psych help [like MDMA for PTSD could have meth for PTSD as a possible substitute). Meth is found more often than MDMA in ecstasy. Another common combination is MDA and MDMA, which is more neurotoxic (you should take it less often to be safe), but considered more euphoric. Just because one thing claims to be something doesn’t mean it is that when it’s illegal. For example people being given fentanyl as heroin.

[@SpaghetteronmySweaty]

@@GogiRegion come to europe where youre gaunteed to only find inactive ingredients in your pill along with high doses of pure mdma

[@maggiep9007]

Spaghetter on my Sweaty There are no guarantees unless you can sue the maker if a pill gives you aids.

[@chaffejcarraway]

Do you have a recommendation of a cheap starter kit or list of glassware to get me started? Like a used chemistry wholesaler from a highschool maybe? I'm looking to do some simple to advanced chemistry experiments following your videos and some other KZbinrs. Thanks!

[@ablackhole5254]

Hey guys, I have 2 questions. Ive been trying to make potassium chlorate from 14% sodium hypochlorate but for some reason im doing stuff wrong. Ive tried 7 times and my only successful run yielded about 3 grams. I was also trying to make nitric acid with HCl copper and a nitrate salt (im only 15 so I dont own a fractional distillation apparatus) from an Erlenmeyer flask with a a tube connected to it. So ive successfully gotten NO2 gas but when I bubble it in water I just get a blue solution( witch im thinking is copper sulfate).And doesnt react whatsoever with copper or silver but it bubble when it comes in contact with lime. So anyone have any ideas on whats up with that?

[@pietrotettamanti7239]

A black hole you are doing things completely wrong. you need ONLY a nitrate salt and a strong acid. copper isn't required. no, you can't use HCl because you would boil away it with the nitric acid. the reaction HCl+KNO3------>KCl+HNO3 is an equilibrium. this means that the products can also react to reform the reactants. to fix this you have to boil off one of the products, so they can't react. this can't be done with HCl because you would boil away it first than the nitric acid. you have to use H2SO4 and KNO3. H2SO4 boiling point is much higher than nitric acid one. you produced NO2 because the nitric acid reacted with the copper. why did you put the copper in that reaction? and why did you think that the blue solution was copper sulphate? there wasn't sulphur in your reactants, how could the sulphate be there? the solution was copper nitrate. for the potassium chlorate i haven't an answer, i don't know your procedure. one last thing to point out: nitric acid, potassium chlorate... even the dumbest chemist would understand what you want to do. I know your reasons, as i am very similar to you and at our age (i'm 16) everything that explodes or burns is intresting. but, trust me, you have to study first. chemistry isn't only breaking bad and explosives. you can't just mix together some shit and watch what happens without understanding as you did with the nitric acid. you will seriously harm yourself in a short amount of time. you can't just study a little bit of chemistry and then searching the procedures on internet. you have to fully learn chemistry and then you will start studying that amazing the branch of explosives. but it is a branch, not the centre. maybe you won't take me seriously because i'm 16. i started studying it 2 years ago and now i'm 2nd at the chemistry games in my country (italy). but I studied hard and i'm not even near to the half of the road. i'm a real chemistry nerd. take chemistry a little more seriously pls

[@MGSLurmey]

Chemistry is dangerous, no chemical reactions should be attempted without properly knowing and fully understanding the reactions taking place. I heavily suggest doing a course on chemistry before undertaking large projects.

[@johnnysternomson9435]

I used the blue aloe vera lidocaine spray once and got lidocaine powder from it by setting a bunch on a plate and let it sit for 10-11 days. All the blue stuff evaporated and left me a white powder

[@NileRed]

+Johnny Sternomson You are going to get a mix of lidocaine HCl and the other stuff they put in there. I mean, unless lidocaine was the only solubilized ingredient.

[@johnnysternomson9435]

Oh. I have no idea but im sure it could maybe be washed somehow?

[@NileRed]

You can wash it with an organic solvent to remove the soluble stuff. This leaves behind lidocaine HCl and other water soluble stuff. Then you need to convert the lidocaine to freebase lidocaine, which is soluble in organic solvent. Then wash with organic solvent and evaporate to get the lidocaine. That should work, but like i said, i had trouble in the past because they include emulsifiers and saponifiers, etc. Makes things annoying.

[@cmg6866]

DEA has entered the chat👮👀

[@Peace-fo1vx]

Thank you so much, you are the best.

[@bigguyzack]

will this work for dxm asking for a friend

[@aidonwelsh8968]

greetings fellow robotripper

[@bigguyzack]

@@aidonwelsh8968 greetings

[@heezywrld]

yooo imagine snorting pure dxm

[@iEatLife]

nopenruu I don’t have to just did it I’ll update you how it was in a few ☺️

[@valforatlas]

Lane Byers how was it?

[@Tgspartnership]

brilliant stuff again

[@parishna4882]

A little something from eMedicine Emergency: The symptoms of lidocaine toxicity tend to follow a predictable progression. The toxicity begins with numbness of the tongue, lightheadedness, and visual disturbances and progresses to muscle twitching, unconsciousness, and seizures, then coma, respiratory arrest, and cardiovascular depression. CNS toxicity: When the lidocaine dose is increased from 1 mg/kg to 1.5 mg/kg, the risk of CNS toxicity increases from 10% to 80%. Symptoms include the following: o Lightheadedness, dizziness o Visual disturbance o Headache o Perioral tingling, numbness or tingling of tongue o Sedation o Impaired concentration o Dysarthria o Tinnitus o Metallic taste o Muscular twitching, tremors With progression of toxicity, the patient may experience tonic-clonic seizures and, eventually, unconsciousness and coma. Seizures generally do not occur with lidocaine levels of less than 10 mcg/mL. Cardiovascular: Excessive lidocaine concentration can cause cardiovascular toxicity, although this is less common than CNS toxicity. Lidocaine is somewhat less cardiotoxic than lipophilic local anesthetics such as bupivacaine. Risk of cardiac toxicity is greatest in those patients with underlying cardiac conduction problems or after myocardial infarction. Potential cardiovascular effects include the following: Negative inotropic effects Effects on vascular tone (with low doses having vasoconstrictive effects and higher doses causing relaxation of vascular smooth muscle) Effects on cardiac conduction include widened PR interval, widened QRS duration, sinus tachycardia sinus arrest, and partial or complete atrioventricular dissociation. Cardiac arrest has been reported after intraurethral administration of lidocaine. Cardiac toxicity is potentiated by acidosis, hypercapnia, and hypoxia, which worsen cardiac suppression and increase the chance of arrhythmia. This is important to consider since seizure makes this metabolic picture more likely. Plasma lidocaine levels of less than 5 mcg/mL are unlikely to have cardiovascular toxicities. Levels of 5-10 mcg/mL can cause hypotension by inducing both cardiac suppression and vascular smooth muscle relaxation. Levels of more than 30 mcg/mL are associated with cardiovascular collapse. CNS symptoms may be masked in patients premedicated with anticonvulsants such as benzodiazepines or barbiturates. The first sign of toxicity in these premedicated patients may be cardiovascular system (CVS) depression. When blood levels are high enough to block inhibitory and excitatory pathways, convulsions cease and the patient experiences respiratory depression or arrest and cardiovascular depression. Large bolus injections may increase peak anesthetic levels to the point where the CNS and CVS are simultaneously affected. I'm gonna do eeeeet !!!!

[@drosophyllum8418]

At 0:18 it looks like an omegle conversation.

[@finchisneat]

How do you know none of the povidone was in the end product, meaning when you crystalized out the caffeine, how do you keep povidone from coming with it.

[@zczonstka]

Title Edit: "Breaking Bored staring HeisenDork"

[@irkvarma7328]

What tablet did you take for the experiment

[@QuestWilliams]

+Nile Red You are extracting lidocaine form personal lubricant. Aren't you?

[@calebbadger]

+The OpenSourceHuman Project Topical lidocaine-prilocaine spray for the treatment of premature ejaculation:

[@QuestWilliams]

Bacon Sanderson Well it does have a much shorter ingredient list.

[@NileRed]

+The OpenSourceHuman Project I will 99% confirm that.

[@RKKDesign]

I was going to guess hemroid cream....smh

[@avilarkspur9266]

Hi bro, can u tell me how to remove pseudoefredine from cough syrup plz

[@aidanstrawn1044]

Lmao

[@pepiggy114]

Hey, nice video! May you try extracting cyanide from apple seeds? I think it would be a cool idea. Thanks!

[@supersophisticated9943]

Don't they combine with your body to make the hydrogen cyanide? I don't think it's already cyanide. I also could've sworn that was just in stone fruits.

[@toxicpsychotic6356]

​@@supersophisticated9943 The cyanide in apple seeds is in the form of amygdalin, a molecule that contains hydrogen and a cyanide group. It only needs to be broken apart in order to create hydrogen cyanide.

[@isabellam1936]

What’s the difference between the active ingredient in Vicks inhaler levmetamfetamine vs and Benzedrex propylhexedrine? Also which works better? I can’t find anything on Google comparing these two active ingredients in over the counter nasal inhaler use.

[@XCyclonusX]

Love your videos. Please consider doing a video about extracting nicotine from cigarettes. Possibly very practical for people wanting to make their own vaping liquids.

[@nunyabiznez6381]

+XCyclonusX If one were to do that it would be less expensive to purchase raw tobacco for that process. Plus the tax would be lower in most cases. many states impose an extremely high tax on finished tobacco products but not nearly as much on raw tobacco leaves. As a business venture those substances are extremely lucrative. In my medium size city there are a dozen separate businesses solely engaged in the manufacture of vaping liquids and most are relatively small start-ups. One started three years ago with just the owner. He has over 100 employees today and has to expand into larger facilities three times since founding. I'm not personally interested in this particular industry but it is definitely a lucrative business and with a huge potential for expansion. If you are producing your own for personal consumption you should also know that you could grow your own legally. It's just another plant and relatively easy to grow. All you need is some land. Or you can grow it in flower pots if you don't own land.

[@rickautry2759]

Practical, but possibly fatal if somebody misplaced a decimal point. I've been using crap pipe tobacco soaked in water overnight as an insecticide for years. The liquid makes a kickass spray, and the soggy tobacco leaves around my tomatoes are for the slugs. (Don't say it- Tomacco! No, there's no murderous goats around yet!)

[@TetraSamurai]

XCyclonusX or just buy nicotine online lmao. You could also extract it from nicotine patches.

[@frankatchison1617]

XCyclonusX I am Pretty sure pure ethanol will release nicotine from tobacco but How to measure the mic's or mill's is beyond me.

[@johnnoland5749]

What is the point of the top beaker slowly leaking the contents into the bottom beeker? What does this process do and is it necessary?

[@elgrone2013]

can i freebase caffeine?

[@TryNHardGamerZ]

+elgrone2013 Snort it

[@Coiltec]

Yeah, but there is no reason to do so. Caffeine freebase (just caffeine) is much more easily available than caffeine salts. In case one has a caffeine salt (for example caffeine hydrochloride or caffeine citrate) on hand, it can be freebased by adding enough sodium hydroxide to make the pH slightly alkaline, and then recrystallizing the caffeine to remove the sodium salt by-product.

[@jackmorgan6344]

Coiltec sodium hydroxide? Why not pickling lime, or sodium carbonate?

[@Coiltec]

Both of those should also work.

[@shadowphyre4746]

I have 2 questions.The first one:So I'm trying to extract some KOH from wood ash but what I'm left is really really dirt like KOH crystals.It's there any way to make them clear without the dirt stuff?The second one:Is there any way to separate KCl from NaCl?I got some kind of salk that have 50% NaCl and 50% KCl and I want to extract the KCl.

[@papaversomniferum5247]

What about extracting scheduled drugs from scripts?

[@NileRed]

I cant do or show that due to legal reasons

[@papaversomniferum5247]

+NileRed I know dude lol thanks for the reply though! You inspire me to be a chemist I've been taking classes at my local community college for 2 years now! I just found ur channel 2 days ago! It helps a lot!

[@markrigsby2107]

Jjaro V You can by just going to a college library.

[@TetraSamurai]

Very easy to do if you have above average knowledge in chemistry. But kind of pointless, why would you want to do that anyway? You'd be spending more money doing it than you would have on the drug itself.

[@atw98]

BaldManLogan dont you get 3 grams per pack cold flu caps for a base cook. So your $7 turns into 600 if mixed with glucose? At least here thats whats added to 25grams glucose to make an once.

[@PREACHERSPROPHECIES]

How can you extract sugars that addhere to other crystals

[@DejaStacy]

I got my stuff delivered discreetly by this mycologist whose get lsd, dmt, mushrooms and more

[@DejaStacy]

Dude is on telegram and Instagram

[@DejaStacy]

@pham_smart1

[@notPlSSFINGERS]

Hey, I couldn't find your patreon in the video description nor on your chanel. :) That beeing said; please don't take this personally but I think your Method is rather unprofessional: I'm sure that you are aware, that Chemicals that are "not" soluble in a certain solution will actually dissolve just in a lower concentration. Therefor it is always neccessary to determine the exact solubility of every component. And whether or not advanced cleaning steps are neccesary. Even trace-amounts could act as a substrate or catalyst for reactions that you did not consider. Thus you could easily end up with a completely different product, which could be dangerous or at least ruin future synthesis etc. I'm aware that this is just a mild introduction but i still want to provide some quality control for your chanel :) I really hope you don't mind.

[@notPlSSFINGERS]

+Phil Becker ok about the patreon, nevermind found it via google :)

[@liamdurkin7327]

can you go over everything you used like what the flasks and materials are called in order to perform this extraction

[@gonzaloboneu8329]

ACETONE FROM CACLIUM ACETATE !!

[@RollLandOh08]

+Gonzalo Boneu damn

[@NileRed]

+Gonzalo Boneu I will be making it from sodium acetate I think. It is easier to get.

[@gonzaloboneu8329]

Holy funking god, My second favorite Chemistry channel Answered me. I'm god today B|

[@NileRed]

haha I am glad to help any way i can

[@gonzaloboneu8329]

Keep on the good chemistry then :D and Thank's . Greetings from Argentina !!