Metabolism | Regulation of the Transition Stage

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[@seratkhanzaki7356]

First of all thanks a lot, the question is where did lipoate come from in second stage of enzyme?

[@Redox23-X]

​@@seratkhanzaki7356 its a cofactor of Pdh complex

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u made biochem interesting........ and no words how to thanku . ur the besttttt teacher

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i love the clinicial aplication of details its make me learn more about the process

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I spent my whole afternoon trying to understand the transition stage but failed. My classmate recommended your channel. Thank you for making this sooooo easy to understand!

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14:37 Regulations

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[@phuongan]

Please let me know if this is a correct way to think about PDH kinase and PDH phosphatase: I like to imagine that they are like the brake and gas pedal in a car. In this case, PDH kinase functions like a break: if you apply more pressure on the brake (you stimulate it) ==> the car will slow down. If you take your foot off the break ==> the car will speed up. On the other hand, PDH phosphatase functions like a gas pedal. In this case, it's pretty straight-forward: stimulate it and the car will go faster; take your foot off (=inhibit it) and the car will slow down

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[@Nxtdoorguy]

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[@ANGELAAR]

Brilliant