Non-inferiority results: everything you need know in 5 mnutes!

This was recorded in March 2020 and intended to help internal medicine residents as they study for their royal college exam.
If you'd like to receive more content relevant to internal medicine you can tune into our podcast: podcasts.apple.com/ca/podcast...
trialfiles.substack.com/

[@dannidiestro]

Amazing!

[@rohanphilip665]

Very clear and concise! Thanks

[@Fralickmike]

You’re welcome!

[@jamesleem.d.7442]

SUPERB presentation.

[@Fralickmike]

Thank you !!

[@Milad_showcase]

Really nice and clear explanation, thanks Michael, really helpful

[@Fralickmike]

thank you!

[@CreamPieMyFace3]

beautifully explained. thank you so much

[@Fralickmike]

You're most welcome

[@potatonail7463]

Really great! Thankyou

[@Fralickmike]

you are most welcome

[@TheVishu27]

One of the best 👍💯

[@Fralickmike]

Thank you!

[@amohadjel]

Incredible!

[@Fralickmike]

Thank you!!

[@DethWench]

Great video! Very helpful slides!

[@Fralickmike]

Thank you!

[@aritrasaha7421]

Very helpful, Thank you.

[@Fralickmike]

Glad it was helpful!

[@sarahashmori8999]

THANK YOU!!!

[@Fralickmike]

You’re most welcome

[@junlizhu2312]

'The noninferiority and inferiority' one makes sense but feels weird lol. Thanks for the wonderful explanation!

[@Fralickmike]

You're very welcome!

[@residentswap697]

Super helpful, thank you! Could you explain in words what a set margin of x (Let's say 20%), would mean? 20% acceptable difference between groups? still struggling with that concept , thanks!

[@Fralickmike]

Our generic ASA is non-inferior to brand name ASA at preventing a heart attack. Oh really? What margin did you set. 20%! And what did your study show? It showed that the upper bound of the confidence interval was only 19%. OK cool, then it sounds like your generic ASA is truly non-inferior.

[@ivytruong4997]

how do you set the 20% margin on the forest plot?

[@rh2996]

Does the margin line must be drawn in the graph? Because I’ve seen in many articles it is not in the graph

[@Fralickmike]

You are right it is often not written in the figure at all. I like to include it when I’m explaining this study design as I find it makes the whole concept easier to understand