Olink Podcast | Ep 21 Complementarity of Mass Spec and PEA

Welcome to the Olink® Proteomics in Proximity podcast!
Below are some useful resources mentioned in this episode:
UK Biobank Pharma Proteomics Project (UKB-PPP), one of the world’s largest scientific studies of blood protein biomarkers conducted to date, www.ukbiobank.ac.uk/learn-mor...
UKB-PPP online resources developed by Nick Lehner and Maria Wörheide
metabolomips.org/ukbbpgwas/
Metabolomics and Proteomics Core in Munich:
www.helmholtz-munich.de/en/co...
www.helmholtz-munich.de/core-...
[e-mail]
ClinspectM (clinspect-m.mscoresys.de/) consortium in the Munich area dedicated to move proteomics forward to clinical application
More joint initiatives towards Germany-wide benchmarking and standardized processes are in the making, follow the news on www.mscoresys.de/
Research articles
Sun, B.B., Chiou, J., Traylor, M. et al. Plasma proteomic associations with genetics and health in the UK Biobank. 2023 Nature, DOI: 10.1038/s41586-023-06592-6
www.nature.com/articles/s4158...
Petrera A, von Toerne C, Behlr J, et al. Multiplatform Approach for Plasma Proteomics: Complementarity of Olink Proximity Extension Assay Technology to Mass Spectrometry-Based Protein Profiling. (2020) Journal of Proteome Research
pubs.acs.org/doi/pdf/10.1021/...
Multicenter Collaborative Study to Optimize Mass Spectrometry Workflows of Clinical Specimens.
Kardell O, von Toerne C, Merl-Pham J, König AC, Blindert M, Barth TK, Mergner J, Ludwig C, Tüshaus J, Eckert S, Müller SA, Breimann S, Giesbertz P, Bernhardt AM, Schweizer L, Albrecht V, Teupser D, Imhof A, Kuster B, Lichtenthaler SF, Mann M, Cox J, Hauck SM. J Proteome Res. 2024 Jan 5;23(1):117-129. doi: 10.1021/acs.jproteome.3c00473. Epub 2023 Nov 28. PMID: 38015820
pubs.acs.org/doi/10.1021/acs....
Olink tools and software
Olink® Explore 3072, the platform utilized by the UK Biobank to measure ~3000 proteins in plasma: olink.com/products-services/e...
Olink® Explore HT, Olink’s most advanced solution for high-throughput biomarker discovery, measuring 5400+ proteins simultaneously with a streamlined workflow and industry-leading specificity: olink.com/products-services/e...
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In case you were wondering, Proteomics in Proximity refers to the principle underlying Olink technology called the Proximity Extension Assay (PEA). More information about the assay and how it works can be found here: bit.ly/3Rt7YiY
For any questions regarding information Olink Proteomics, please email us at [e-mail] or visit our website: www.olink.com/
Interested in a specific podcast topic or guest? Reach out to us at PIP at olink.com
WHAT IS PROTEOMICS IN PROXIMITY?
Proteomics in Proximity discusses the intersection of proteomics with genomics for drug target discovery, the application of proteomics to reveal disease biomarkers, and current trends in using proteomics to unlock biological mechanisms. Co-hosted by Olink's Cindy Lawley and Sarantis Chlamydas.

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