Oral minoxidil - a universal, safe medication for hair loss due to any cause. Dermatologist explains

Topical Minoxidil has been used for many decades to promote hair growth. Due to the potential side effects of high dose oral Minoxidil for hypertension, the oral formation was not used for alopecia. However, low dose oral Minoxidil seems to reduce the side effect profile of the mediation without any decrease in its effectiveness of promoting hair growth. This video looks at the various hair loss conditions where low dose oral Minoxidil has been used, the dosage needed, the potential side effects and a dosage strategy for its use.
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[@irianramos1778]

Amazing! couldn't love more a scientific review vídeo. Wish every explanatory vídeo would be like this.

[@DiscoverDermatology]

That is a very kind comment! Thanks so much. Im glad you found the video informative!

[@ashwajitsingh007]

As I’m a post graduate student in dermatology… I can safely can that the things you tell aren’t there in any text books… that’s why whenever I see your videos in my feed I Instantly click them…. Another good one sir

[@DiscoverDermatology]

Thanks Ashwajit, you are very kind. Glad these presentations are helpful for you.

[@Tamizsaelvi]

Dear Dr.Diwa,absolutely an eye opener for even OG cians like me.Your presentation is as usual crisp and clear.The slate chalk type slides and perfectly scrolling references attracted me.I strongly hope it won t be an offence to start using minoxidil on my patients .Thank you for the wonderful information.

[@DiscoverDermatology]

Thanks TS. It seems too be a safe treatment that anyone can start and monitor. So should be no problem for you to prescribe it.

[@RohanYesudian]

Very detailed breakdown of the use of oral minoxidil for alopecia!

[@DiscoverDermatology]

Thanks Ro!

[@lakshmipriyamanimaran2906]

Hello, doc. First of all i am appreciating you how much effort you are putting for one video is really great and inspirational despite your works. It shows us how much you love your profession . And the way of delivering the information is crisp and clear. Hats off to you sir😊

[@DiscoverDermatology]

Thats is so kind of you to appreciate the video, thanks so much! Glad you found the information helpful. And yes, I do love to teach and help others!

[@rogerricrads9855]

Thanks for the good overview!

[@DiscoverDermatology]

You're welcome!

[@robertbach9085]

Thank you for the excellent review!

[@DiscoverDermatology]

Welcome!

[@kaiser-ki6wp]

Excellent video. Thank you for sharing your knowledge.

[@DiscoverDermatology]

Glad it was helpful for you!

[@1957es]

Thanks for not dumbing this down and actually helping those of us who need to know the pluses and minuses. My doc gave 2.5 2xd and I’m in another bp med. I’ll take your advice over her prescription any day. Don’t twant to die in my sleep.

[@DiscoverDermatology]

With long term oral medications for a chronic conditions like hair loss, the usual protocol is to start low and work up according to the response. Generally, in the Uk we start at less than 1mg for women and 2.5 mg for men and then increase every 8 weeks or so dependant on the response. The dose should be tailored according to the individual persons response.

[@vgibbs12]

Thx so much for very informative vid definitely gave me the confidence & more importantly clarification I needed to move forward with taking oral minoxidil.

[@DiscoverDermatology]

Glad the information was helpful! I did another video that gives information on the dosages and side effects. Here it is: kzbin.info/www/bejne/gKbVe36VqLh9d7s

[@rajeshderma]

Thanks for the update

[@DiscoverDermatology]

Welcome Rajesh!

[@dr.ratnakishorerkskinglowc6816]

Thanks for the information SIR

[@DiscoverDermatology]

You are welcome, glad it was helpful!

[@ashakumari11_]

I am very Glad to find your channel.. Thank5 for very informative videos..🙏🔱💐 Just wanted to know sir can this treatment re grow lost hair

[@DiscoverDermatology]

Yes it can stimulate hair growth and result in some lost hair regrowing again

[@AjayDas-nt6lq]

Sir how can i get loniten in india and plz tell its high doses

[@bree5075]

Hi Dr Diwa, what about oral minoxidil's effect on collagen? Dr Hasson ( a reputable Hair Surgeon) has gone on record saying that HT patients who have been using minoxidil have degraded scalp skin.

[@DiscoverDermatology]

Interesting point, thanks for brining it up. I have not read any reports of problems with collagen when oral minoxidil is used. I could not find any reference on this topic on a PubMed search either. Perhaps it is a possible effect of topical minoxidil? There is no mechanism I can think of wherein oral minoxidil can affect collagen. With topical agents, some of the other constituents in the solution or foam can irritate the skin and therefore have an effect of the local collagen.

[@dulidp1]

Very useful..👌👌👌

[@DiscoverDermatology]

Thanks Duli, glad it was helpful.

[@petesantana7302]

I tried topical minoxidil for 3 months and developed topical dermatitis. I attempted to apply to my arm and chest to test if I would develop skin irritation and did happened a redness and bumps. Can I attempt oral or I need and allergic test to this medication? Thank you for your great video! Peter

[@DiscoverDermatology]

It appears that you are allergic to one of the constituents of the topical minoxidil. It is very rare to have an allergy to minoxidil, so its likely to be one of the preservatives. Its certainly worth considering oral Minoxidil. Maybe take a test dose of 1mg and if you experience any allergic effects, then avoid it. I suspect it is unlikely to cause problems though as oral allergy is quite different to contact allergy.

[@ank4273]

Thank you so much for this video.🙏🏻 I (F, 41) was just prescribed Minoxidil (Loniten) 2.5mg (1/2 a tablet every night) and Teva-Spironolactone 100mg (1 tablet every night). I have female pattern hair loss and according to my dermatologist this could be genetic. When I asked my dermatologist if there could be any side effects after starting this treatment she said no. However, I just read the information sheets that were given to me by the pharmacist and the first thing they say is that Minoxidil can cause serious heart problems and worsen chest pain amongst other potential issues. Reading this made me feel very uncomfortable to say the least. Knowing that I'll have to take both of these medications for the rest of my life I was wondering if there could be any long-term side effects, or any other issues? My dermatologist said that we'll do a blood test every 6 months to monitor the kidneys and potassium levels. I was also wondering if it's allowed to drink some alcohol every once in a while while on both medications. I usually don't drink much (maybe 1-2 twice a month at the most), but would this mean that I would need to give up alcohol all together? Is it also allowed to take Ibuprofen and Acetaminophen when on this treatment? I deal with migraines almost every month, and usually take both painkillers together. Thank you kindly.

[@DiscoverDermatology]

The doses of minoxidil used for hair loss are usually very low and it is unusual for it to cause heart problems or chest pain. It also generally does not interact with alcohol so an occasional drink is allowed as are painkillers. Here is video on the dosage and side effects of oral minoxidil. kzbin.info/www/bejne/gKbVe36VqLh9d7s.

[@ank4273]

@@DiscoverDermatology Thank you very much for your reply.

[@ned9344]

Hi I'm 36 with diffuse thinning on the top and a Norwood 2 would minoxidil be effective for me? I'm also on 1mg finesteride, thanks

[@DiscoverDermatology]

Both Minoxidil and finasteride are used together commonly for all stages of hair thinning.

[@ryanmorgan1215]

I'm a physician. This was way more helpful then I thought it would be, so thank you. I take minoxidil. took 1.25 bid for 3 months with improvement but felt like it more paused hair loss than improved density so with my doctor's permission increased to 2.5 bid. Now having the sensation that someone is poking their fingers constantly under my xiphoid and an increase on inotropic effect on heart beat but no tachycardia or pedal edema. I haven't heard any diminished heart sounds or rubs. I'm wondering if there is a difference in taking daily vs bid and have considered doing 3.75 daily.

[@DiscoverDermatology]

Thanks for your kind words. As you mention, it may be useful to take 3.75mg a day as this may reduce any cardiovascular side effects. Taking it at night before bed is another useful strategy. At present, there is no evidence that taking it twice a day is more effective than once a day.

[@molho761]

Hi doctor, I have been using topical minoxidil for over 10 years, and I intend to start treatment with oral minoxidil 2.5 as well. Do I expect fewer side effects due to the previous use of topical minoxidil? And is it worth continuing with topical minoxidil at the same time as using oral minoxadil? Thank you very much

[@DiscoverDermatology]

Oral minoxidil is easier to use than topical minoxidil. Its less messy and does not irritate the skin. Side effects of the tablets depend on the individual but at 2.5mg it will hopefully be minimal. Using just one would be sufficient as they work in the same mechanism. Maybe have an overlap period of about 4 to 6 weeks to give the tablets a chance to kick in before stopping the topical minoxidil if you are worried about sudden cessation of the topical agent.

[@monicajoseph4163]

Very helpful

[@DiscoverDermatology]

Thanks Moni!

[@JamesBonsor]

Would you advise starting on 1.25mg oral minoxidil for someone who have never used this substance? Thanks.

[@DiscoverDermatology]

Yes, the usual starting does for women is 1.25mg and for men is 2.5mg. Here is a video on dosages and side effects. kzbin.info/www/bejne/gKbVe36VqLh9d7s

[@YRishavSingh]

what is the process to switch from Mintop Forte 5 percent to oral minoxidil 5mg without shedding?I have to completely stop using topical and want to switch to oral minoxidil 5mg.

[@DiscoverDermatology]

There is no particular regimen suggested in the literature. One option may be to gradually introduce the oral minoxidil and then once both are established, gradually reduce topical minoxidil and stop it.

[@Drunk3nMonk3y72]

Hi Dr, I’m in the UK, could you prescribe me this medication if my GP doesn’t?

[@DiscoverDermatology]

Hi, most GPs will be able to prescribe KT for you. Sometimes they may want a dermatologist to assess the hair condition first. It may therefore be useful to have a consultation with the local dermatologist as they will want to examine the scalp and make sure there is no other condition co existing with the reduced hair density. I can prescribe it if you live in the UK bit as mentioned an assessment is needed first and that I best done by a local dermatologist. I practice in the Northwest, in Chester.

[@architpandey6052]

Is it necessary to take any other suppliment as combination with oral minoxidil for androgenetic alopecia ? Or can we just take minoxidil tablet only?

[@DiscoverDermatology]

Hair loss usually has multiple factors and this video explains more about it. kzbin.info/www/bejne/f4G7g6uCbNdnjcU Addressing all the factors mentioned in the video in addition to oral Minoxidil may be the best way of managing hair loss.

[@hosamalabrach7511]

Hi Doctor, thank you for your information. Would like to ask if impossible to do a Combination Tofacitinib 5mg and Oral Minoxidil 2.5 . Appreciate your response thank you

[@DiscoverDermatology]

We can use both but JAK inhibitors like Tofacitinib are used only for specific conditions like alopecia areata. Here is a video on the topic kzbin.info/www/bejne/hXm3qoidm9qIjrc

[@hosamalabrach7511]

@@DiscoverDermatology thank you doctor for your reply but is it safe to use both

[@colton3268]

Hello, my trichologist prescribed me 1.25mg of finasteride every day and 5mg of oral minoxidil twice a day for 6 months and then 5mg once a day for another 6 months. What do you think, is this a too high dosage of minoxidil? I'm a 21 year old guy, Norwood 2

[@DiscoverDermatology]

All studies on oral minoxidil for hair growth use a maximum of 5mg a day, so the dose that you mention is high. Here is video that looks at dosages and side effects kzbin.info/www/bejne/gKbVe36VqLh9d7s

[@purringinmyear.1512]

Hello, Have there been reports in the reduced effectiveness of oral minoxidil over time?

[@DiscoverDermatology]

Oral minoxidil is relatively new and we do not have long term data on it yet. I suspect there will be some loss of efficacy with time as the androgen sensitive hairs will undergo some reduction due to the hormonal influence

[@kayumochi]

I am a male who took 2.5 mg for 5 months with wonderful new hair growth. However, the other week, I suddenly had to stop exercising one day because I lost my breath and strength. I took a few days off from the drug then started it again at a half-dose and sometimes I still find myself out of breath. What do you recommend?

[@DiscoverDermatology]

It is incredibly unusual for side effects in such low doses, particularly when there have been no symptoms for such a long time. It may be useful to see a physician to exclude other causes for the breathlessness.

[@Nisha.37]

Hello doctor, I'm suffrage androgenic alopecia from last 2 years, I have been using topical minoxidil from last 8 months but result was 0%, and 3 months ago I noticed irregular period and my gynecologist said I have pcos and prescribed me spironolactone and contraceptive pills, but for hair loss I'm still without solution, do you think in my case should I ask doctor for oral minoxidil, will it work for me?

[@DiscoverDermatology]

Yes, using low dose oral minoxidil with spironolactone is a good option. You can ask your own doctor to prescribe this.

[@christianblake3997]

Hi Dr Diwa, I just come across your KZbin channel and I’m blown away by how insightful and pleasant your presentations are I just wanted to ask one question if taking I’m taking 5 mg of oral minoxidil daily should I split the dose in two due to the fact that it leaves the system fairly quickly do you suggest taking 2.5mg in the morning and 2.5mg in the evening or would it be better to just take one 5 mg tablet daily?

[@DiscoverDermatology]

Thank you very much for such kind words! I am so happy to note that you find the information helpful. With regards to dosage, there is no specific guidance on taking oral Minoxidil once or twice a day. Most studies suggest once a day dosage and from a practical point of view, I would prefer once a day dosage as we are less likely to forget if we have to take a medication only once rather than twice a day!

[@inderjeetbhatia6380]

Dear Doctor, I have been diagnosed with FPHL grade 2 and I have been on oral finasteride 2.5mg (for 1 year) and oral Minoxidil (started with 0.0625 for 2 weeks, 1.25 for 2 weeks and 2.5mg for 9.5 months). I have seen increased hair shedding for about 8 months, and it continues. (At the same time as I started full dose Minoxidil ie. 2.5mg, I got A cell PRP also done). Will the hair shedding EVER reduce or stop? Will increasing or reducing the dose of Minodixil help to reduce hair shedding? Is the hair shedding seen with Minodixil use proportional to the dose? Thanks

[@DiscoverDermatology]

Its unusual to get hair shedding for such a long time with oral minoxidil. It may be worthwhile considering other oral agents with your dermatologist. Here is a video on another medication that could be useful. kzbin.info/www/bejne/qHe6f3SgfraLeck

[@shubhampratap3298]

Can change of dosage of minoxidil ( tab)from 1.5 to 2.5 mg ,too lead to shedding if yes what will the duration??your opinion doc

[@DiscoverDermatology]

Yes it can but only for a short period of time, maybe about 2 months, then it tends to stabilise again.

[@rishavkumar7225]

If i am taking vit c boiled eggs veggies low salt less sugar and intermittent fasting to boost my collagen ..will it then compensate the effect oral minoxi has on skin wrinkles

[@DiscoverDermatology]

There is no scientific evidence that minoxidil causes skin wrinkling. Maintaining skin health with natural means is always the preferred option. Here are a couple of videos on this topic. kzbin.info/www/bejne/eXOVdWaEirmteqs kzbin.info/www/bejne/maLZnqdsl76KfKs

[@MuhammadHusain-wb7rz]

Plz tell me sir treatment for aelopia

[@DiscoverDermatology]

It depends on the cause of alopecia. Minoxidil seems to work for alopecia of all causes. Knowing the cause is helpful as other treatments can also be used. It is best to consult a dermatologist for it.

[@hadhad129]

hi how do i get this prescribed my doctors in ontario 2 didn't prescribe it, i have 1 more to ask and we will see, any other options even 0.5mg is fine

[@DiscoverDermatology]

It needs a prescription in the UK but most GPs and dermatologists are able to prescribe it. Not sure how the health system operates in Canada I’m afraid.

[@hadhad129]

@Discover Dermatology so far I asked 2 in Ontario gonna ask from different province if not seems like a nation thing perhaps

[@mirnasamy95]

Thankyou dr. For helping How can i reach your contacts for consultation please ?

[@DiscoverDermatology]

I work in the UK, so I can only see patients based here Im afraid. I work in the Nuffield in Chester and in Spire, Wrexham.

[@servantofthecreator]

I don’t see any results with 5mg is oral minoxidil dose dependant meaning if I take higher than 5mg I will see better results?

[@DiscoverDermatology]

The medication needs to be sued at a certain dose for at least 4 months before we can examine its efficacy. The current evidence is based on studies of Minoxidil at a dose of up to 5mg a day. For hair loss, higher doses have not been studied, though it can be used at a dose of 10 to 40mg for hypertension. It may be useful to consult a dermatologist as other medications like finasteride could be considered if Minoxidil alone has not given enough benefit.

[@titliD4955]

Hello sir , I'm a 24 year female with Fphl , I have been using topical minoxidil 5% for 7 years . It has stopped showing significant effect lately. My hair is thinning. Can i switch to oral minoxidil ? Will it be effective? Please reply

[@DiscoverDermatology]

Oral minoxidil is certainly an option of topical minoxidil is ineffective. Oral Spironolactone is also used. Here is a video on it kzbin.info/www/bejne/mmTMioZ8h6mVjJI #Disclaimer# Please note that this video is for education purposes. It is not meant for personal advice as your own doctor/dermatologist will be the best person to answer specific queries.

[@vinaypenta4391]

Sir my doc recommended me oral minoxidil 2.5mg for my hair thinning.. I have been using it since 4 days when can we except the hair growth increasing

[@DiscoverDermatology]

It will take about 2 to 3 months to note any change in hair density.

[@NickArcade]

Does propranolol block the hair growth of oral minoxidil?

[@DiscoverDermatology]

Thats an interesting question! Just looked at the literature and I could not find any article that shows any interaction between the two in hair growth. They are used together as anti blood pressure agents so there is no reason to believe that they will counteract each others actions. Let me know if you find any research contrary to what I have mentioned.

[@aadilrasheed2984]

I was taking oral finasteride and i experienced sexual problems like decreased ejaculatory volume and painful ejaculation Besides frequent and painful urination occurred and burning of urethra like sensations upto the base of bladder...... Could these problems be associated with oral finasteride doctor?

[@DiscoverDermatology]

Oral finasteride can sometimes cause various side effects, including the ones you mention. It is important to rule out other causes as well, like a urinary tract infection.

[@siamosht]

Can one stop using Finasteride once hair has thickened due to Minoxidil use?

[@DiscoverDermatology]

Yes, thats certainly possible. Its hard to know what will happen after stopping finasteride as there may be hair loss again in some. Topical finasteride may be a useful compromise long term.

[@Nade444]

Hi doctor, I live in the UK and my dermatologist will only prescribe me spironolactone because she thinks taking 2 blood pressure lowering pills is not advisable. . She won’t prescribe oral minoxidil. Would you be able to prescribe it to me online? How do I go about it? I have been diagnosed with androgenic alopecia

[@DiscoverDermatology]

Hi, I am not sure where you live in the UK. Usually, there are other dermatologists who may be able to prescribe the medication in your city or town. It is always helpful to get treatment from someone whom you have seen face to face. This is because a full assessment may be prudent before prescribing the medication. Other scalp conditions should not be missed as minoxidil alone is unlike to help if there are associated skin conditions. I practice in the Nuffield in Chester and in the Spire in Wrexham, so you can contact these hospitals for an appointment. However, ideally a face to face appointment would be very helpful for both you and for myself to assess the scalp condition.

[@Nade444]

@@DiscoverDermatology I’m Milton Keynes/London area. I’m really struggling to find a derm who prescribes oral minoxidil. Thanks anyway

[@MyLifeInDebt]

I am wondering if you ended up getting it. My General Practice physician here in the US had no problem prescribing me spironolactone and minoxidil simultaneously

[@Skenderbeg100]

I've also been taking dutasteride and oral minoxidil for close to 9 months now and seeing great results myself. My hair is getting thicker and thicker. I actually have to undergo surgery, in which the doctor told me to stop taking dutasteride and oral minoxidil for 1 week before operation. If I do as the doctor instructed, will I lose the hair that I've grown right away and does it have to take a few months without taking those pills for that to happen?

[@DiscoverDermatology]

It usually takes a few months for any hairs to fall, so if the surgeon had suggested stopping them, it would be best to follow his advice.

[@Skenderbeg100]

@@DiscoverDermatology Thank you.

[@kartik9314]

Hey brother i am taking 1mg finasteride for 3 months now and not seeing any improvement. Should I start taking oral min 2.5mg or wait for 3 months more to see the result of finasteride?

[@DiscoverDermatology]

@@kartik9314 1mg is a low dose for men. A better dose may be 2.5mg as mentioned in the video.

[@akhil1993ify]

After having it for 4 months in 2.5 mg, i have observed tenderness and swelling in my chest area, is this a side effect?

[@DiscoverDermatology]

It is unusual to develop side effects at low doses especially after a few months. Sometimes, stopping treatment to observe if the side effects settle is one way of knowing if the medication caused the problem.

[@mernagobran9952]

How about intitial shedding?

[@DiscoverDermatology]

Yes, just as topical minoxidil can cause temporary hair loss initially, oral minoxidil can do the same. It stabilises as it is used for longer periods.

[@SurajBatavia]

@DiscoverDermatology can I take 2.5 oral minoxidil and men's nutrafol with DHT blocker instead of Fintaside?

[@DiscoverDermatology]

Minoxidil can be combined with most other oral agents. I have not heard of Nutrafol but it seems to be natural supplement so it would be fine to take the combination

[@SurajBatavia]

@@DiscoverDermatology okay thank you should I try oral Finasteride to see if that works for me and how much MG dose should I start off with the least side effects. 0.5mg or 1mg?

[@DiscoverDermatology]

We can use oral finasteride with oral minoxidil. We tend to start with lower doses, about 0.5mg a fay before increasing it. @@SurajBatavia

[@SurajBatavia]

@@DiscoverDermatology Hello, I have started taking 1.25 oral minoxidil a day for two days now and the left side of my chest feels tight. Should I continue taking or should I try topical minoxidil or stop oral minoxidil. I have a dog so that's why I tried oral minoxidil first but have this side effect. Please help. Thank you!

[@DiscoverDermatology]

It is unusual to get side effects after such a small dose. It may be useful to contact the doctor who prescribed it for you - a full check including listening to the heart would reassure everyone that there is no problem. Then the oral minoxidil could be continued. @@SurajBatavia

[@Blackbeard1084]

Can oral minoxidil and dutastride be combined ? What is the ideal dosage for stage 1 receding hairline

[@DiscoverDermatology]

Yes, both can be sued together. For men, the usual starting dose is 2.5mg a day. Here is a video on the doses and side effects of oral minoxidil: kzbin.info/www/bejne/gKbVe36VqLh9d7s

[@shubhampratap3298]

​@@DiscoverDermatologywhat will you recommend for grade 3 hair loss doc?? ( Fin + min) your suggestion about their dosage ??

[@DiscoverDermatology]

Any stage may benefit. This video looks at the indications and dosage in more detail ​@@shubhampratap3298

[@chomu3596]

Thoughts on a 18yo getting on 2.5mg oral min a day? Would it be safe long term?

[@DiscoverDermatology]

Minoxidil will help, but it needs to be used lifelong so it will need careful consideration in an 18 year old. It may have leas side effects compared to other Ora medications for this condition.

[@vikaschandrakar9784]

hi doctor i dont have any hair loss.can i eat 2.5 mg minoxidil for 2 months. if i will discontinue then will i loss any hair.

[@DiscoverDermatology]

Usually, any hairs gained by oral minoxidil will be lost when it is stopped. It will help thicken those with normal hair but the added hairs may fall when oral minoxidil is stopped.

[@justinherbert9146]

7:40 start at 2.5mg increase 1.25mg every three months with 5mg max

[@DiscoverDermatology]

Here is another video on dosages. kzbin.info/www/bejne/gKbVe36VqLh9d7s

[@Jim-oc3sp]

Just switched from topical minoxidil (after many years) to oral minoxidil (1.25mg) due to losing ground. I've also been on Finasteride for many years. Although my hair fall had increased, which is why I made this change, in the last 30 days since using oral Minoxidil, I'm noticing ALOT of hair fall. I was hoping it was a temporary shed but because it started prior to me using the product, I'm not sure. Any input is appreciated, thanks.

[@michaelblue4619]

well did you stop using finasteride ?

[@DiscoverDermatology]

There is usually a period of temporary hair fall for ups to 90 days as the telogen or resting hairs are shed. One option may be to increase the dose of Minoxidil as men usually need about 2.5 to 5mg a day. Serial images of the hair parting will also help to be a bit more objective.

[@Jim-oc3sp]

@@michaelblue4619 No, did not stop Finasteride. I began taking oral Dutasteride around the same time as my oral Minoxidil. I take the Dutasteride every 3 days, while taking the Finasteride on the other days.

[@Zakkary]

@@Jim-oc3sp How's it going?

[@Jim-oc3sp]

@@Zakkary Unfortunately the same. Still plenty of hair fall (hopefully just temporary shedding) but I do see some hair with bulbs, which is not typical. My derm stated that I have a combination of not only Androgenic Alopecia, but also Telogen Effluvium and Lichen Planopilaris so the typical remedies may not work for me as much as others who are only suffering from male pattern hair loss. I do start microneedling in 2 weeks so hoping that helps stimulate some growth. I haven't experienced any sides with the oral Minoxidil so thinking to up my dosage to 2.5mg is probably next step. I checked my bloodwork to ensure that my FIN/DUT combo isn't negatively affecting my testosterone and that has been confirmed (positive).

[@nawrinalamnabila5818]

I'm a female and want to start oral minoxidil and spironolactone for hair loss. Is 1.25mg oral minoxidil and 25gm spironolactone a good combination for hair loss and new hair growth? I have been losing so much hair can see bald patches now. So depressing. Also do I need to take any birth control pills with it? I'm 31, unmarried. Please reply. Thank you.

[@DiscoverDermatology]

Prof Sinclair from Australia first reported the combination of oral minoxidil with spironolactone. It seems to be a very useful combination as one counteracts the other. I have discussed this in a recent talk which I enclose below. Spironolactone can harm the baby, so contraception is a must whilst on this treatment. There is no good data about oral minoxidil in pregnancy, so pregnancy is best avoided with this too. kzbin.info/www/bejne/ZpTUeYCNbM2mna8

[@nawrinalamnabila5818]

I'm unmarried, 31, not pregnant. Do I still need to have birth Control pills with spironolactone?

[@DiscoverDermatology]

Anyone who is sexually active needs to be on contraception if they are on spironolactone. If anyone is not sexually active and not at risk of pregnancy, then of course contraception is not needed. @@nawrinalamnabila5818

[@saleemwani534]

Sir I have been using 5% minoxidil and finasteridine topical solution for six months besides taking finasteride orally for this period on alternate days..I hv seen good resilts... Niw my Dr has suggested me to go for minoxidil 2.5 once daily for 15 days followed by 2.5 twice daily for 15 days and then again shifting to 2.5 daily for rest of life... Pl advice is it fine to use this regime or should I remain on topical solution only as I am comfortable using that..

[@saleemwani534]

Just to add my age is 47 years and I am a male

[@DiscoverDermatology]

The literature suggests a slower increment in oral Minoxidil. Here is a video that gives information on how to use the right dose increment for oral Minoxidil kzbin.info/www/bejne/gKbVe36VqLh9d7s

[@augustya7543]

Dr so if someone is starting Oral Minoxidil 2.5 MG dose for the first time, does he need to be on a lower dose like 1.25MG for some days before he scales it further to 2.5 MG ? If Yes, how many days should one be on a 1.25 MG dose before switching to 2.5 MG dose ?

[@DiscoverDermatology]

For men, we can start at 2.5mg a day (1 or 1.25mg for women). For long term conditions like hair thinning, it is better to start at these low doses and work our way up. Each dose will take at least 3 to 4 months to work, so can titre up the dose after 3 to 4 months, increasing uo to 5mg in men.

[@augustya7543]

@@DiscoverDermatology So Dr do you mean if a Man starts it at 2.5 MG for Hair Thinning, he should take the 2.5 MG for atleast 2-3 months before scaling it up to 5 MG ?

[@DiscoverDermatology]

@@augustya7543 Yes that is right.

[@shubhampratap3298]

​@@DiscoverDermatologywhat if he is recommended 1.5😅😅!! Can we directly shift to 2.5 per day

[@DiscoverDermatology]

The usual practice is to use a low dose and then increase. The lower dose may be more than sufficient fort hair growth in many

[@Lil_Dwag]

Dear Dr. I started with 2.5mg treatment and increased it to 5mg and developed a persistent mucus and burning on my throat and cough. My doctor said it would probably not be caused by Minoxidil but I am not convinced. I stopped using oral min and started asthma inhalers and started feeling better. Is coughing a known side effect on oral min?

[@DiscoverDermatology]

It is not a usual side effect of Minoxidil. Maybe you could try using it again once the cough and other symptoms have completely resolved and use only a low dose to see if that will help without giving side effects?

[@eudespottier]

is oral minoxidil more likely to cause facial hypertrichosis than the topical? i developped severe facial hypertrichosis on the face from the topical . thanks

[@DiscoverDermatology]

I dont think oral minoxidil is more likely to produce hypertrichosis than topical. As long as we keep below the threshold dose of 4mg for males and 2mg for females, the chances of hypertrichosis is diminished.

[@eudespottier]

@@DiscoverDermatology my brother developped really bad body hypertrichosis from oral minoxidil 1.25 mg , way worse than with topical

[@DiscoverDermatology]

@@eudespottier That is most interesting. I have not encountered it in any of my patient, probably because I start with a low dose in females. I have used it only for a couple of males without any problems. There may be a genetic predisposition for it too. Thanks for letting us know of the potential problem this can cause.

[@jayeshaw5705]

@@DiscoverDermatology isn't hypertrichosis one of the main side effects of oral?

[@DiscoverDermatology]

@@jayeshaw5705 It is, but is dose dependant. The hairs tend to be the fine lanugo like hairs on the face in most and therefore patients do not seem to mind this as they see good thick hair regrowth in the scalp.

[@neharikagoel486]

I’m 31 year old female, married and completed family with 2 kids. One dermatologist suggested 1.25mg minox and another suggested 5mg finast. Which one would you recommend? Is finast safe for women?

[@DiscoverDermatology]

The use of medications is usually each physicians choice and there is no right or wrong. Personally, I use oral minoxidil and tend to avoid oral finasteride in women. However, there are studies which show that finasteride has been successfully used in women too.

[@neharikagoel486]

Thank you for your time and the prompt reply. What can be the side effects to expect with a dose of 1.25mg? Should I start with 0.625?

[@DiscoverDermatology]

Amy staring dose can be tried. Some start at 0.625 but others start at 1.25. There is no right or wrong dose. Here is a more comprehensive review of this topic kzbin.info/www/bejne/ZpTUeYCNbM2mna8 @@neharikagoel486

[@AjayDas-nt6lq]

Sir kindly tell me which brand oral minoxidil is best for hair loss disorder in india plz kindly reply me

[@DiscoverDermatology]

I am unaware off any specific brand that is superior. In the UK we tend to use Loniten

[@AjayDas-nt6lq]

​@@DiscoverDermatologysir how can I get loniten in India and plz tell it's maximum dose for hair loss

[@DiscoverDermatology]

@@AjayDas-nt6lq I think it is available through your doctor, if the brand is mentioned. You may be able to buy it online from abroad too though I am not sure how it works in India. Here is a video that mentions the doses of minoxidil that is recommended. kzbin.info/www/bejne/gKbVe36VqLh9d7s

[@jenxsj3902]

Is it dose-dependent? If I have no side effects can I take 10 mg per day. My blood pressure is normal/very slightly elevated.

[@DiscoverDermatology]

The studies for hair loss only go up to 5mg a day. If 10mg is taken it is above the usual recommendations by dermatologists. Here is a video that I did on the doing of oral Minoxidil kzbin.info/www/bejne/gKbVe36VqLh9d7s

[@hasanalmaiuf2897]

🛑 Hello Doctor Should the tablet be taken with water, or should the tablet be placed under the tongue and sucked? Because I heard putting it under the tongue and sucking it in this way has a benefit and speed in liver enzymes and the like. I am not a specialist, but this is what I heard. Is there an answer, Doctor? And a second question, please Can I take it before bed with finasteride at once or do I make each medication a different time Thank you doctor❤❤🎉

[@DiscoverDermatology]

Great question. I have done a video on sublingual minoxidil and have mentioned your name. Look out for it this Friday! Taking both medications at th same time improves compliance.

[@hasanalmaiuf2897]

@@DiscoverDermatology Waiting for that video on Friday.. Thank you🌺

[@Jim-oc3sp]

What is the equivalent of 5% topical minoxidil when switching to oral? 1.25? 2.5? 5? Other?

[@DiscoverDermatology]

From my reading, I do not think there is a direct correlation between the topical and systemic doses. The dose will need to be titrated according to the effect on the hair. Increasing as mentioned in the video would be the best option.

[@aadilrasheed2984]

Oral minoxidil has a massive range of side effects on cardiovascular problems like palmonary hypertension, cardiac failure, angina, pedal edema and problems in heart rythms Thus don't go for saving hair by losing life

[@DiscoverDermatology]

Fortunately, a low dose of oral minoxidil may avoid many of the series side effects

[@arunkv1903]

I am 30 years old male with grade 7 baldness. I have recently done hair transplant two weeks ago. I am taking biotin daily. Planning to start taking 1mg oral Finasteride daily for 6 months and then planning to take it on alternative days without increasing the dosage if no progression of baldness is noticed. Also, planning to start 2.5mg of oral minoxidil 3 times a week. when to start taking minoxidil after hair transplant? is this a right approach?

[@DiscoverDermatology]

It is a very sensible approach. Oral Minoxidil can be started at any time, even as soon as the surgery is done.

[@kartik9314]

Sir I am 28 year old male taking finasteride 1mg for 3 months for DHT. But not seeing much improvement. Thinking of trying 2.5mg oral minox. I am on zinc and vitamin E supplements. Kindly provide me your valuable suggestions.

[@DiscoverDermatology]

Think 2.5mg would be better for men.

[@kartik9314]

Can i take both finasteride and oral 2.5mg minox for hair growth? What's the duration to notice some improvement in my hair thickness and density??

[@DiscoverDermatology]

@@kartik9314 Yes, both can be taken together. Usually hair growth is assessed after 3 to 4 months.

[@kartik9314]

@@DiscoverDermatology thankyou Sir for giving prompt reply. I hope after 2 3 months I can gain thickness in my hair.

[@DiscoverDermatology]

@@kartik9314 All the best! Patience is key and waiting for 3 to 4 months will tell us how effective the treatment is.

[@DaxaLL]

Sir how to quit oral minoxidil after achieving results

[@DiscoverDermatology]

It may need to be continued long term as that is what most of the studies suggest

[@anandprakasheng0253]

Do normal hair also get dependent on oral minoxidil after using it .i am taking 2.5 mg minoxidil daily for hairline issue

[@DiscoverDermatology]

All hairs respond to minoxidil, so the positive effects tend to regress when we remove the medic action. Here is a more comprehensive review on oral minoxidil. kzbin.info/www/bejne/ZpTUeYCNbM2mna8

[@anandprakasheng0253]

@@DiscoverDermatology so do I need to stop oral minoxidil for hair line recession?

[@DiscoverDermatology]

If there is excessive regression of hair loss, it may be worthwhile trying something else. @@anandprakasheng0253

[@sherifdoc]

Have been on 1.25 mg oral minoxidil daily for 1 week. It works very fast as I noticed less hair loss now. However, since I started 1 week ago, I have been feeling tired, lazy and low energy. Will this persist or it’s temporary ?! I don’t want to stop it but I’m concerned about this fatigue. Any advice ?

[@DiscoverDermatology]

Feeling tired is an unusual side effect for Minoxidil and I have not come across it before. I guess any side effect can occur with any medication. Usually the body tends to adjust to any medication after a few days so it may be worthwhile continuing the medication for a few more days. Another option is to reduce the dose and take it on alternate days rather than everyday and then gradually titrate the dose upwards?

[@mansooresfandieyar5860]

Did you shed?

[@sherifdoc]

@@mansooresfandieyar5860 no. But honestly I had to stop it after 1 week -10 days of using it. I was feeling so bad, tired, lazy, low energy, terrible puffy eyes, and even low sex drive. Once u stopped it, it took me 3-4 days to get back to normal and feel better. I strongly believe that oral minoxidil has a lot of side effects and that it’s not only vasodilators. I strongly believe it has a hormonal effect. I used the topical for years with no side effects at all except the hair dryness. Once I used the oral at very small dose, I felt so bad.

[@mansooresfandieyar5860]

@@sherifdoc that’s sucks. You’re in the 1% unfortunately

[@sherifdoc]

@@mansooresfandieyar5860 I know I’m sensitive to DHT blockers. Finasteride screwed me up in the past. Didn’t expect oral minoxidil to do the same, but it was very clear that it has something to do with androgen receptors. And it’s not in my head btw.

[@rishavkumar7225]

1.25 oral minoxi in male Low salt intake ..no alcohol Will it still lead to puffy face and eyes

[@DiscoverDermatology]

It is very unusual for such a small dose to cause facial puffiness unless there are other underlying medical conditions. It may be best to contact your general doctor to look for any other causes of a swollen face. Hair dyes can also cause puff face and eyes. Here are a couple of video on it kzbin.info/www/bejne/j6bVqmmwpJppmKc kzbin.info/www/bejne/p3i3h6iLobZ3gLM

[@rishavkumar7225]

@@DiscoverDermatology can i hit the gym if i am taking 1.25mg oral minoxi and 1 mg finasteride

[@DiscoverDermatology]

Being fit is useful for any skin condition. Minoxidil and finasteride can be used whilst exercising. @@rishavkumar7225

[@user-om1de7cv5u]

like topical minoxidil ..there is down fall in oral minoxidil. if yes then wht we can do increase dosage?

[@DiscoverDermatology]

Initial hair loss can occur with both oral and topical minoxidil. It usually stabilises after 6 to 8 weeks so continuation of the treatment would be the best option. If there is no response within 3 to 6 months, it is unlikely to work.

[@titan3537]

I think he asking about reduced efficacy over time (tolerance)

[@titan3537]

​@@DiscoverDermatology Can we take hydrophilic tablets like dutasteride or oral minoxidil also sublingually or sublinual route is only for lipophilic tablets? Will the effects differ?

[@DiscoverDermatology]

@@titan3537 There is no evidence for tolerance, but the beneficial effect may be lost once the medication is stopped.

[@DiscoverDermatology]

@@titan3537 Good question, At present we do not have evidence that hydrophilic tablets work in the sublingual route. The sublingual minoxidil has to be specially prepared. Here is a video on it kzbin.info/www/bejne/m5zcqXiladaXrNU

[@gadigadigadigadi]

Is 2.5 safe for heart? So many people online complain

[@DiscoverDermatology]

It is still a very low dose and I am yet to have anyone with side effects with this dosage.

[@gadigadigadigadi]

@@DiscoverDermatology thanks doc. appretiate the response.

[@muppidisusmitha4843]

Sir can I have online consultation

[@DiscoverDermatology]

Hi, its very kind of you to ask. I am registered for practice in the UK, so if you live here, then it is possible to treat you. The medication is , however, available through your own GP or doctor if you request it. Oral Minoxidil is available through any doctor, not just a dermatologist.

[@ncmen1]

Sir . I’m a 35 year old female and suddenly experience severe hair loss 6 months back . I’ve been diagnosed to have androgenic alopecia with receding hairlines … my doctor in India prescribed topical minoxidil but it’s giving me severe scalp itching , I wanted to know if I can changeover to oral minox 1.25 once or twice a day . My biggest concern is I’m planning to start a family 6 months from now so can i go about it ?

[@DiscoverDermatology]

Oral Minoxidil may be a better option if there are side effects with topical minoxidil. It can be used for the next 4 to 5 months and will then need to be stopped before trying for a family.. Sometimes changing there the topical minoxidil solution to minoxidil foam may also reduce the skin sensitivity and is worthwhile trying.

[@DiscoverDermatology]

Here is a video that looks at the possible side effects of oral Minoxidil too kzbin.info/www/bejne/gKbVe36VqLh9d7s

[@ncmen1]

Thank you so much sir . This is very help . I have another doubt with regard to finasteride . My husband has been on it for years and I’ve heard mixed opinions about stopping finasteride before starting a family . Is it required to stop oral finasteride before family planning ? If yes then for many months earlier sir ??

[@DiscoverDermatology]

@@ncmen1 I am not that keen on oral finasteride for women. I prefer oral Minoxidil. Finasteride should be stopped before pregnancy is considered though I am not sure how long before. To be on the safe side, I would suggest ate least 3 months before.

[@ncmen1]

Sorry sir . Maybe I wasn’t clear . my husband is on finasteride . And I’ve read studies which say it can alter semen parameters and cause dna fragmentation . But there are also some who say it doesn’t affect . My husband is scared that If he stops finasteride for a couple of months he will loose more hair . So wasn’t sure if he had to stop it ? If yes for how many months

[@ArisAris-ku7np]

Doctor can I use 2.5 mg for 6-8 months oral minoxidil and then switch to topical without losing my gains ?

[@DiscoverDermatology]

From the data we have till now, Oral minoxidil is more effective than topical minoxidil. So some of the hair gain can be maintained when oral is changed to topical minoxidil but there probably will be some hair loss, which tends to be different in each person.

[@ArisAris-ku7np]

@@DiscoverDermatology thank you For reply !! Is it safe to use it you think iam 25 years old

[@DiscoverDermatology]

@@ArisAris-ku7np Yes, it is a safe drug. The only factor ro consider is that it needs to be continued long term and due to your age, this may be many years yet!

[@ArisAris-ku7np]

@@DiscoverDermatology thank you doctor

[@jayeshaw5705]

@@DiscoverDermatology which study are you referring to that oral is more effective than topical?

[@ashwinkarthik7053]

Sir are u Dr.Patrick yesudaiyan's son?

[@DiscoverDermatology]

Yes Ashwin, Prof. Patrick Yesudian is my father. He has done quite a few videos that are in this channel.

[@user-wh5ro6xb9c]

Hello Dr, my daughters are 13 and 11 years old and they have female pattern baldness. Can oral minoxidil be given to them ? If not pls suggest some other treatment . Pls help. Thanks

[@DiscoverDermatology]

It is very unusual to give oral minoxidil for such young children. It may be useful to assess the reasons for hair loss first. Usually nutritional factors are important in young girls. Here is a video that explains the causes of hair loss. kzbin.info/www/bejne/f4G7g6uCbNdnjcU

[@user-wh5ro6xb9c]

We are unable to find any reason Dr. Their hair is getting thinner day by day, giving all the supplements like iron, vitamin d, using hair serums but nothing is helping. Can you suggest some line of treatment at this age ? Thanks

[@DiscoverDermatology]

@@user-wh5ro6xb9c A specific diagnosis will need to be made. Perhaps a skin biopsy could be considered by the dermatologists? Without knowing the cause it is difficult to treat the underlying condition.

[@user-wh5ro6xb9c]

@@DiscoverDermatology Dr , is there any way I can connect with you ? I am in India. Thanks

[@DiscoverDermatology]

@@user-wh5ro6xb9c Im afraid my practice is only in the UK so it will be difficult to help those outside theUK.

[@gobin3777]

Doctor I am 18 , should I take oral minoxidil

[@DiscoverDermatology]

Anyone above the age of 18 can take it. However, it needs to be taken long term, so that is something that will need to be considered.

[@gobin3777]

@@DiscoverDermatology can it cause any severe side effects

[@DiscoverDermatology]

The side effects are as described in the video. None are severe but need to be aware of potential problems.

[@DiscoverDermatology]

@@gobin3777 From my experience with this medication, it have been v safe and I have not had any major side effects at all. This is because we use v low doses in dermatology

[@gobin3777]

​@@DiscoverDermatology Is 5mg a low dose

[@jakubklinger2289]

Oral minoxidil gave me heart palpitations even though it was very effective.

[@DiscoverDermatology]

Thanks for the information, it is useful to know. My patients have not experienced it though it is mentioned as a side effect in many reviews.

[@DefundTheFringes]

Most guys don't mind more general body hair growth, I suspect. For women it's a worry.

[@DiscoverDermatology]

That is a good point!

[@srijayasrijaya9590]

oral minoxidil side effects shortness breath

[@DiscoverDermatology]

That is quite a rare side effect and occurs in those with pre existing heart problems or those on high doses of the medication

[@srijayasrijaya9590]

@@DiscoverDermatology i start oral minoxidil one day before i take ECG everything is normal and after one month i have shortness breath

[@DiscoverDermatology]

@@srijayasrijaya9590 That is unusual in lower doses. Tr to use the lowest dosage, maybe on alternate days as that may cause less side effects

[@srijayasrijaya9590]

@@DiscoverDermatology ok sir

[@beaglesnlove580]

Hey doctor, I am a male and have been taking 2.5mg since October and have been having awesome results. Also I sometimes use 3.75mg. But noticed recently that I’m getting tired on oral minoxidil and whenever I sleep and wake up, my head feels spinning for 5 seconds. Curious if this warrants a complete stoppage or should I cut down the dose to 1.25mg? Thanks

[@DiscoverDermatology]

Tiredness is not a common side effect of the medication. the spinning sensation off the head may be postural hypotension or reduced blood pressure on getting up. Have you tried taking the medication in the evening rather than the morning? A slight reduction in dosage to 1.25 or 2.5mg may be helpful if Minoxidil is the cause of the symptoms.

[@beaglesnlove580]

@@DiscoverDermatology curious can oral minoxidil be taken once every other day instead of daily?

[@ITZME11592]

Do u use any other hair stimulants like topical minox Or oral finas?

[@beaglesnlove580]

@@ITZME11592 oral dutasteride

[@DiscoverDermatology]

@@ITZME11592 Usually most would have tried topical Minoxidil, so this is s step up and I ask them to wean off topical minoxidil once the oral minoxidil is established. Some may need oral finasteride too but this is decided on a case to case basis.

[@chirkovanatasha]

Hello dear doctor. I found your channel and wanted to ask if I can consult with you on Skype? I am from Russia and we don't have oral minoxidil there and I'm looking for a doctor who could send it to me for a fee, of course. How can I contact you?

[@DiscoverDermatology]

Thank you for your comment and request. As I have licensing privileges only in the UK, I am not allowed to treat those outside this country Im afraid. My medical indemnity covers only those in the UK. I would suggest that you get the medication from India or other countries where pharmacies will be willing to prescribe it for you. It can then be monitored by your own doctor in Russia as the side effects from this medication seem minimal and can be overseen by any doctor.