Organs-on-chip: the electro-mechanical perspective

Seminar organized and promoted by the CNR-IEIIT Institute
Thursday seminars - Taking a Look at the Future: a cocktail hour event!
Speaker: Prof. Massimo Mastrangeli (Delft University of Technology)
Title: Organs-on-chip: the electro-mechanical perspective
Abstract: Organ-on-chip (OoC) technology is rapidly being established as a valid approach to develop in-vitro models of human (patho)physiology of unprecedented relevance. Advances in the technology involve co-development of the biological substrates and the design of supporting hardware enabling eminently microfluidic perfusion, electro-mechanical actuation and electro-chemical sensing. In this lecture, I will introduce the perspective of fully-electric OoCs and of OoC platforms, meant to foster ease of use, wider adoption and superior reproducibility of the technology. I will argue that virtually all relevant functions in OoCs can be driven and controlled electro-mechanically, and exemplify how this is best achieved by a seamless integration of electric and fluidic layers in the architecture of the platforms.
Link:
www.cnr.it/it
www.ieiit.cnr.it/it/
www.tudelft.nl/en/