p53 Tumour Suppressor (2016) by Etsuko Uno wehi.tv

p53 protein plays a central role in determining whether a damaged cell lives or dies.
Animation by Etsuko Uno wehi.tv
wehi.tv

[@gelatinocyte6270]

I wish there were more animators like Drew Berry and Etsuko Uno.

[@iViewVaranasi]

Yeh❤️

[@soldadito34]

@gelatinocyte6270 keep watching crap like steven lgbtqia+ unvierse and never ecist good animators like these.

[@tylercriss6435]

These videos are just splendid. They solidified my fascination with molecular biology!

[@andreabernardini7575]

Beautiful rendering! The flavour of transcriptional regulation neatly emerges from this video. Well done.

[@Andy-rl8dq]

I love this video and this channel, I learnt about p53 at uni two years ago and this animation brings it to life!!

[@musicspinner]

This is incredibly well done. Wow.

[@floraye453]

I really like your animations. I think biomedical animations are very important for us to learn more about tiny things happening inside our cells. If you don't mind, I would like to ask your permission to share these videos to the other website in China for the embarrassing reason that KZbin is blocked from accessing in China. Also because China now has rare beautiful animations about molecular biology. Of course, I will give sources of the original website. Thank you very much!

[@MouAresounTaPneusta]

I felt it when it said that enviromental stresses cause cells to either die, stop growing or repair themselves. I am between the latter two.

[@songthanh896]

Thanks so much! So informative!

[@stevemotoq1411]

Nice production job well done ,,☑️

[@xxeclepticxx]

Extremely impressive!

[@ghadaabdelrazik2239]

Stunning!

[@cultivando-ideias]

É POR ISSO QUE EU VOU SER UM BIOINFORMATA!!! SIMPLESMENTE PERFEITO

Excellent biochemistry!

[@hpsauce1078]

Mindblowing

[@glz1]

Wow little machine going to work beautiful

[@konanko169]

awesome !!!!

[@jaminhubner6342]

Seriously need to get some of those scenes into a free screen saver for computers and phones. Would boost your audience.

[@pandeyistrying]

This is great

[@mayanksangam9205]

Amazing

[@regulate.artificer_g23.mdctlsk]

I'm not sure if I'm seeing this correctly, but it looks like the molecule models here include the hydrogen atoms. Usually these atoms aren't included, so it's nice that they're shown here - if that is the case.

[@SeanRhoadesChristopher]

This is amazing but not so easy to understand for the layperson.

[@htowngurlL]

i could not watch because of the buzzing noise :(. i still liked

[@lucvandermeeren]

Amazing video showing the complex inner workings of the cell. I'd like to know how you make it.

[@rodrigomoreno11]

amazing video!! is there a way we can have the full tetramerized Tp53 in PDB format to 3d print please?

[@LuizRibeiroAcademico]

Good animator, congrats

[@giantqueermess264]

but what if the gene that dicided groth arest, death, or repair is the gene thats broken??

[@user-ed7gm7ol8k]

nice

[@spek2554]

What happens if you eat food containing cancer cells or tumor?

[@avestator3763]

Nothing, our stomach is filled with chlorine acid and a whole range of enzymes which disassemble every Protein and DNA in the cells into their very basic parts to be used again by the body. Even if they wouldn't or you would inject cancerous DNA into your blood system, Cells aren't made to take up any DNA lying around and using it for themselves, they can't. DNA outside of Nuclei or even cells is most likely viral and the Body destroys it and would never integrate it into their own system.

[@regulate.artificer_g23.mdctlsk]

If your food contains cancer cells, that means you're eating raw meat. Nothing will happen, of course, the cancer cell will just get digested.

[@mmarquesrj40]

Poxa tnha que têm em português, rs

[@d1dac0]

DNA must be unique to earth and we must be alone because there is no way something like this could evolve out of nothing in other part of the universe.

[@user-xh9pu2wj6b]

why not? And why do you think Earth is that special?

[@coreymanago9684]

And with that can you find a cure ?.

[@alwynwatson6119]

So why is P53 turned off? Is it because the DNA that tells the cell to produce P53 is damaged by radiation or chance?

[@danielkron2513]

Yes

[@oluiolujk1025]

kzbin.info/www/bejne/bn7TaHdtpryrfZY

[@howtodoit4204]

Daniel Kron yes what

[@agata_cz]

Because it is mutated to be switched off, and this can occur through damage caused by radiation or chance mutations. Every day, your cells mutate, some mutations are harmless, and few are deleterious/harmful, but radiation and UV light can increase frequency of mutations especially harmful ones. Humans have only 2 copies per genome per cell of p53 and it’s easy for us to loose one and have the other switches off. In contrast elephants have more copies of p53 and are less likely to acquire cancer. p53 is the most important rumour suppressor which causes cancerous cells to die, plays a role in a couple of pathways in the cell life cycle. Cancer is an uncontrolled cell growth, where cells grow out of the organs and in wrong places, and reproduce rapidly without control. You can find more on Google and in biology books, but hope this helps.

[@alwynwatson6119]

@@agata_cz I was thinking if you had a correction enzyme that specializes in correcting p53 mutations as well as mutations in the DNA that contains the instructions for this enzyme then you would have a better resistance to cancer. Of course if there was some necessary reason for p53 to be turned off then that would explain why this has not evolved.

[@MsShigeyuki]

I wish this video should be translated in french :(

[@WEHImovies]

Ask Passe-Science Thomas Cabaret to do a French version kzbin.info/door/sz9DiwPtgDvxJ-njWnieZw

[@MsShigeyuki]

@@WEHImovies grand merci :) Thank you indeed have a nice day

[@mrmust2780]

The term WEHI means the message from Allah in Islam. Is your channel name related to the Wehi in islam?

[@WEHImovies]

No, the name WEHI comes from our longer (former) title, the Walter and Eliza Hall Institute of Medical Research

[@ichigo_nyanko]

can you tell me the term in full? how do you pronounce and write it? when I typed 'WEHI' on google it doesn't appear.

[@mrmust2780]

@@ichigo_nyanko Vahiy

[@KucingAhong]

Maha besar Allah atas ciptaannya yang sempurna

[@Zmax15]

Lol whut?

[@terozak4140]

This is nothing but a program ...