Parkinson's Disease (Shaking Palsy) - Clinical Presentation and Pathophysiology

[@armandohasudungan]

🧠 TEST YOUR KNOWLEDGE FROM THIS LECTURE! ✅ youmakr.ai/test-playground/questionnaire/673d42de859b9c170836eeac

[@prem5864]

I am a doctor and I can say , this is by far the best pathophysiology explaination I have heard .

[@sonavarghese7146]

Are u sure this is all correct?

[@lapharmacie98]

I can’t believe it, every single topic in physiology and patho I’ve ever needed some help with Armando has a video on it. What a legend

[@lightblue3747]

Yeah!! He has been helping me throughout my med school! 🥰🥰❤️❤️

[@aribabatony4035]

Thanks you DR Rorpopor Herbal on KZbin for curing my herpes totally God bless you DR Rorpopor Herbal on KZbin contact for any candy of sickness.....💯

[@adrenaline9182]

You can help me out? Though

[@aribabatony4035]

@@adrenaline9182 kzbin.info/door/kZwKW6qES4dXDWzb0YQErA

[@Mosinee565]

👏👏

[@barbarabrennand7016]

I studied neuropsychology in my work with learning disabilities. This is the best information I have seen to explain Parkinson's on a neural level. thank you so much for this info.

[@andresbadilla3220]

You did this 6 years ago, and here I am, getting it clear. You are a blessing.

[@anushakarukola]

I never thought it could be easy to understand such tough topics in a simple manner with less efforts ❤️❤️

[@MaitsaaRihhadatul]

The most clear explanation of Parkinson disease pathophysiology in whole KZbin ❤️

[@MaitsaaRihhadatul]

6:20

[@MaitsaaRihhadatul]

8:20

[@mokhles703]

This only explains the akinesia/bradykinesia, what about the tremors and the hypertonia?

[@iqraahmad2451]

I can't believe you have explained it so well. I have been dwelling on research papers for so long to connect these points.

[@dr.s.choudhury8089]

Not all heroes wear capes. Some make amazing video lectures for med students on youtube. Armando: The true legend! 🥰

[@aleksandrassaraskinas713]

Thank you mister for making easy to study neurological diseases. It really helps me to prepare for exam!

[@doc.jayantsingh9236]

wow really helpfull in understanding the complex biochemical interaction at tissue and cellular level . thanx

[@drtanveerahmed3373]

This guy deserves a Nobel.

[@gloriaakinyode3279]

VERY NICE VIDEO OF Parkinson dz. Never heard anything so CLEAR and detailed of Parkinson

[@c.b.2]

This was absolutely brilliantly explained! Thank you so much! I'll be sure to send all my med school classmates here!

[@Scrubsandscreens]

This is the best I am not kidding . I am shocked how beautifully someone can explain such a complicated topic

[@MaekaElaKimDimayuga-qx9rp]

I subscribed because the information is very detailed. And for a nursing student like me, it helps very much. I will recommend your channel to my classmates...

[@cesarmichaelalvaradoibarra4215]

Amazing explanation, neurology it's one of the most complicatedsubjects in medicine and you make it look so simple. Keep on the good work! (y)

[@robertofernandez7195]

Nice. It is nice to mention that the Striatum naturally produces Acetylcholine, which also over induces the inhibitory pathway contributing to that Bradykinesia seen in Parkinson's. Great job!

[@robertofernandez7195]

Since ACh is a pharmacologic target in Tx Parkinson

[@travisgrenke]

fantastic video. my roommate has parkinson disease. thanks for posting

[@symbyxbiome]

Beautiful illustrations - a great way to teach. Thank-you. Would be good to better understand or explain some of the changes found in the gut microbiome of people living with Parkinson's, not just the brain.

[@net28573]

If I had resources like this video back in 2009 I would have self diagnosed my SSRI-induced-parkinsonism a long time ago. The most helpful point in this video for me is the differentiation of D1 and D2 in this motor circuit. You just saved me hours of research, good sir!

[@Dayv7]

Brilliant as ever! Thought it was going to be a nightmare to remember the dysfunctional pathways involved but this makes it a cinch.

[@IR240474]

Thank you for this, great instructions and I love the pictures, I make mind maps but I will add this to them today for my exam tomorrow.. Thumbs up who is also cramming for exams!

[@christinevakas92]

Wow, I really like in particular how to summarise the whole picture, how you show us the whole picture at the end, so helpful. When I see your video in our class readings, I know I am going to get great grades. Thank you for sharing your knowledge and talent.

[@oliversykez7292]

Thanks for this in a nutshell explanation! Very helpful in the end stages of studying for USMLE!!

[@sdazxcf]

u r amazing to draw such complicated neuroanatomy into clear figures! salute to u

[@ummejoynabhabiba9484]

Thanks for your amazing videos! Love from Bangladesh 🇧🇩

[@essamalielmisherghi9693]

Thank you so much , this was really great Video lecture. Dr.Essam Elmisherghi from Libya.

[@croock3]

This a great video, fantastic for all levels of understanding and with amazing drawings. Really helpful, thanks!

[@laurenjohnstone9765]

You are magic.You make complex concepts seem so simple

[@Greanestbean]

Great video, I only wish it also included treatment

[@Self-actualizer]

Thank you so much for all the efforts for making the concept sooo easy❤❤

[@mariacabreragonzalez2]

I really like to watch these videos for some context before I study my teachers slides, this was great. Thank you!

[@user-fh7lo6si8f]

Four months TRACKING improvement FIRST STEP: a UPDRS test, a push test with video, a walking and turning test with video, a talking test with video and possibly a writing test, standing from seated on hard back chair video with your arms crossed. These videos are kept on file to be used for comparison with future videos. This is a fairly accurate means of documenting improvements over time as it is actually fairly easy for some people to not realize how much they have improved over time.

[@daocherry7014]

it helps a lot for my upcoming board exam. Thank you!!

[@leemouzee]

Thank you so much! you explain so well and clearly, much better teacher than our professor.

[@danjbundrick]

Fantastic lecture. I learned a lot. One request: please throw that yellow marker away.

[@XxwoodyleexX]

+Daniel Bundrick agree.. it's too pale..

[@danjbundrick]

Indeed.

[@danielbedford6539]

are you Yellow?

[@AsgarAli-wh9vl]

Danimal Bunjee hi danimal i have a problem

[@nectarandice]

Another request: please throw the yellow marker at Daniel Bundrick.

[@vishaldesai464]

Thanku so much sir...I understood clearly about Parkinson disease from this video..

[@buzzlair27]

This was really helpful for my next test, thank you so much.

[@alessandrasousa3402]

ozone

[@maryaali9375]

mashaALLAH u have a very best way of teaching weldone sir kindly upload stroke ms hangtinton diesease vestibular disorders

[@abhisheksinha4605]

very concise n informative,thnx for video

[@balukujoseph3714]

So amazing I understood the pathophysiology finally from here

[@ЈованаКијановић]

wow thank you this saved my life literally

[@ju_7114]

Thanks you! You’ve taught me Parkinson’s in 14 minutes when my professors couldn’t teach it in a 2 hour lecture

[@okomosimon9941]

you are very bright. thank you for your share. i have read pathophysiology PD but i was not understanding. Now i understand it

[@mercyngeru3924]

This was very helpful. Thank you so much

[@alexisdaniel3313]

Could you explain why there is no tremors during sleeping? Why tremors start a couple of minutes after awakening ?

[@MrFASSOLY1990]

Little bit complicated 😅 Thank you for your great efforts 👍🏻

[@EduLuminescence]

Armando sir, you are just awesome...I am amazed... beautifully explained...love from India...

[@celestie02]

Great work sir!! 11.48 when you said hope it makes sense, yess

[@Enceladus007]

Have to play this again.

[@bintenur6684]

Very nice and easier presentation. Thanks

[@lupo_mangiafrutta]

hi, do you have other videos on the basal ganglia or the neuro circuits? thanks i love your videos, you're helping so many med students out there :)

[@MPPSVennached-zd7yg]

Nice explanation sir

[@AyushiRai04]

Great Explanation! But how come smoking comes under protective measures?

[@gulnazpathan4868]

how amazing u explain us awesome memory sir u hav u really gorgeous ,,wonder,,fabulous ,,marvelous i really respect u plls make vdu over coma n epilepsy, schizophrenia

[@dr.varsha8810]

Awesome lecture! Easy to remember.thank you

[@anuradhamehta8281]

Thank you soo much sir for putting up this video 👍👍 It's amazing and time saving too !

[@BintyMcBintface]

Thank you so much for all your videos, I find them a fantastic resource!

[@l.g.a.8930]

Excellent presentation. Many thanks :)

[@AaRtI0404i]

Thank you for the video. Can you please do a video on Traumatic brain injury?? Pleaseee....

[@Homoeopathicore]

I am Classical homoeopathic physician Homoeopathy is a science which treats holistically... Basic principle is all individuals are different so every individual is treated and given medicine totally different whether 2 individuals or more suffer from same disease... Not only this any individual who is suffering from one or many diseases at a time only one medicine will b given on the basis of his constitution... During case taking ( His medical history his family history his emotions intellect delusions fears hobbies choices manners sensitivity will power dreams physical general pathogonomic generals and peculiar symptoms and modalities all are taken into consideration to give his contitutional medicine...) Thats why in homoeopathy every disease is curable whether it is genetic auto immune chronic etc...

[@philipmilner9638]

I have many of the symtoms you mention (some of my relitives thing I have Parkinson's disease), but I have many other illnesses including cerebral palsy, epilepsy and others). Should I try and see my doctor?

[@keruanmendonca6220]

Very good explanation

[@tushardesai256]

I watched it over and over..... question 1: why dint the excited glutamatergic neuron in subthalamus which stimulates the gabaergic neuron in GP.Interna , didnt stimulate the gabaergic neuron in the externa ? Quest 2: Why didnt glutamatergic neuron in the striatum , not stimulate the gabaergic neurons ( the one towards the GP.Interna)? Anybody please answer.

[@A4arooj]

i really needed this, thank you so much.

[@raghadsrj3525]

You are literally the best!!!! keep going man and thanks a lot for ur efforts. Much appreciated

[@TheChantelleBell]

perfect timing. csn you do one on alzheimers and cjd

[@almaquejada6893]

It caught me off guard knowing that smoking is actually a protective factor of Parkinson's disease 🤯 and coffee! Could anyone explain it to me? In my ignorance I thought those were actually risk factors.

[@pharmacistkhan5969]

Plz through that yellow marker... good lecture

[@96areejfatima11]

Thanks a lot for all of your videos.

[@srinivasyadavkasraveni7497]

Fantastic explanation sir love you

[@wonderer112]

Thank you for posting very clean explanation.

[@jonathanespach7876]

Still no cure? Why is this such a difficult problem to solve

[@aliabdallah7833]

This was vey helpful, thank you very much!

[@rethnagireeshwar7199]

admire you for this effects and effort . Thank you

[@worldofwaali2750]

Fantastic video!! I have a question though. I can see that the glutatamatergic receptor in the subthalamic nucleus also synapses back with the GABA-ergic receptor in globulus externa. Wouldn't increased glutamatergic input to globulus externa then lead to inactivation of the subthalamic nucleus?

[@eddel.6003]

Can you do one on Alzheimer's diseases and what occurs in the brain when the develop AD.

[@incognito5064]

You are a brilliant and talanted person

[@riaraizada7387]

Amazing content 🤩. Thank you 😊🙌🏻

[@bhargavibk3383]

A very good video sir! Thank you so much!

[@charmedbabe64]

How is smoking a protective factor against Parkinson's? Does the nicotine help somehow?

[@stubbornaneed]

That was part of her name if you didn't notice she chose it, she is proud of it, and that is cool, so let me ask you, was the word "necessary" necessary?

[@stubbornaneed]

ok, hope you got it right.

[@charmedbabe64]

The name is from a Marina and the Diamonds song.

[@DrArjunKataria]

it makes release of dopamine so somehow make it working.. same like ejaculation decreases chances of prostate cancer in men

[@cesusjhrist3913]

Yeah, smoking weed helps as well, it's on youtube btw, look it up, a patient was really stoned but his tremor was absolutely gone. Ofc, it's temporary, but still is a thing.

[@Dreeblet]

Thank you very much, this helped my understanding of parkinson greatly :D

[@Dennis.bergkamp]

Thank you.You help me a lot for my research.

[@fihimefihi]

concise and rich, thank you for the video

[@toyagobhu7242]

Wowww..vry vry beautiful explanation👌

[@Nikomas6885]

Nice information... hopefully i can find how to cure my brain... 👍🏻

[@dineshphysio7462]

awesome lecture sir... keep going on...

[@hoangminhhoang9900]

Thank you so so much. My teacher makes me confusing in this disease when her talks about its pathophysiology. How can I get the HD picture of this lession?

[@Veruvir]

Loving the detailed flow diagram.

[@jaumepp1975]

Brilliant!!!

[@vickiryan7474]

Incredibly Helpful THANK YOU

[@acousticankit4408]

If in a normal person. The last GABA neuron gets inhibited than how the signals are transmitting to thalamas

[@SuperJanni82]

Thank you so, so, so much! Really awesome video!

[@drmannanbajwa8402]

You’re doing amazing work ..Thank you so much 😍😍

[@tinomutasa5371]

Amazing videos all round. Thank you

[@GregSr]

I did not understand any of it, but it was fascinating nonetheless. I came here because I think I have the beginning signs of Parkinson's. I'm 67 years old.

[@ala_education]

kzbin.info/www/bejne/eomTcp-tZsSBsNU watch and follow this

[@fathimafathima4509]

Thank you soo much.. it was a nice explanation❤️

[@ahmadqubo]

came in time ! thanks armando :D

[@nathanvanderbelt3639]

I love my new INBRIJA inhaler. Anytime I feel an off period I just use my inhaler and I’m back on within minutes of using it.