Parkinson's Disease Drugs

[@smoovlatino]

I am speechless at how gifted you are in teaching. We must protect this man.

[@HarshPatel-he2vh]

From whom? no one hates him😭

[@aneesazafar9646]

You are remarkable, I have never met a teacher like you.

[@silviamontisci6399]

Italian medical student here! I'm glad I found you on YT, you're such a life-saver. Thank you for sharing your passion for these subjects, you're amazing man! (and your staff too, of course)

[@deerfashion]

Starting an assignment on PD meds for my pharmacology class today! SO perfect!😍

[@Aahana1511]

Keeping coming back to this channel and im never disappointed

[@iNeverRez]

I am always fascinated watching Zacks lectures. It always blows my mind how we humans are able to figure this all out. How!?!?! Its amazing and thank you for sharing!

[@ella-meow1116]

please please continue making pharmacology videos ,as pharmacy student i find these so helpful thank you for your effort

[@tanveerabdullah3297]

Kindly make videos on antidepressents and anxiolytics ...plz

[@niharikasaraf3506]

I never bothered learning WHY we used COMT and MAO B inhibitors before this video, damn thank you!!

[@francescacovre7526]

You are my saver for any exam preparation

[@sadiajafar5792]

I love the way you you teach I think your are the bestest teacher in this whole world 🌍

[@AnnMulvihill-lt9qz]

You are Excellent. Great teacher. Thanks from retired RNBSN with Parkin sons. Still with thrist for knowledge to understand. Thanks.

[@bachaspatisubedi9854]

I recently cleared my post graduation, all the basics that u taught was like never been taught or studied my me.. Thank you.. You are just awesome.. Heartly gratitude 😊

[@jis2937]

I’m grateful for your existence, you do matter & we appreciate u

[@faisalqasmi9543]

Be healthy sir 🙏 we really need you

[@direxsama258]

didnt watch this yet but without doubtes i know it will be a BANGER Thank you Dr

[@SH-eh6wx]

God bless you in the ways you do not even imagine!

[@khalilahd.]

So helpful. Thank you! ❤

[@HollyBoyer-j4q]

Your videos are absolutely saving me so I can pass pathophysiology and pharmacology in my NP classes. After I watched your videos, every topic made sense to me. Thank you for what you do.

[@Lotus-iz3ic]

Actually I've been struggling with Parkinson's drugs and mechanisms as I used to hate pharmacology the first medical year in college but this video definitely make it way too easier , I am really feeling grateful, thank you a lot ❤❤❤❤ you are the greatest 💪🏻

[@biybimaryamjoldasbaeva506]

Thanks a lot for the perfect lecture!

[@leticiadermith9832]

You have a gift and I am so grateful for your existence on this earth and time.

[@Yousef-tn1kh]

i passed my exam cuz of you, OG

[@faiza.m9974]

Amazing this video save me, I spend many days to read textbooks and watching my lectures and I feel so dumb but now this video is totally make sense to me and put everything I’ve read together, thank you so much 🎉

[@ayanafrancis6294]

You are a saviour .Thank you zach🔥

[@mmsah30]

i love u man, u made it easy on me to understand the topics

[@mariakara4848]

the best teacher ever🌹

[@mohamedkhyrat7372]

Thank you so much for everything❤

[@madisonwatt329]

Your videos are amazing! Clears up so much information left out by professors! Thank you for everything you do.

[@louyjarbouah]

thanks a lot for the way of informations 😘😘😘😘😘😘

[@user-sb7rs4tp2l]

we need more pharmacology videos

[@chinnyogbonna6506]

I love your passion and teaching, always amazed. Thank you very much.

[@ranlove47]

As always another great video. Wife recently diagnosed with Parkinson’s. Been doin a deep dive into high does of B1 (thiamine) for treatment. After adding it to the treatment made a huge improvement over the meds (Rytary $$$$$). Would love to see a deep dive into why/how this mechanism might work. Most doctors don’t know or haven’t heard of this treatment. Obviously no money to be made on a vitamin. Thanks again for you dedication.

[@steveh1460]

That would be a great topic to cover!

[@fallenangel8785]

you are a great human being

[@yvonnevillalba7722]

You truly are the best teacher ever! Thank you for this video.

[@ladydeebigandcute2681]

Let this man open his university ❤

[@nazaninshahnahad837]

wish i had a teacher like you in my med school, your are amazinggg😍

[@obvankinndy7063]

Antiparkinson's drugs and hypnotics vids are on time, if only the antipsychotic drugs are on the list it would have been just geeat

[@ricardor2166]

Great quality

[@zainabfarooq5263]

I comment for you before I watch the lesson because I’m sure you are great

[@you---can---do---it---23]

Hey guys,i have a question and i would appreciate any help. The cholinergic neurons ultimately have an inhibitory effect on the motor activity of both the direct and indirect pathways. In the video, Ninja Nerd mentions that a tremor arises from overlapping activity of the direct and indirect pathways. However, if both pathways reduce motor activity, it doesn't seem like there would be a contraction of the agonistic and antagonistic muscle, which is what would lead to a tremor. Do you understand what I mean? So do you know if I may have misunderstood something, or how else does tremor occur? Also, Rigor would be illogical if motor activity were reduced, but we do have Rigor, just like Tremor, in Parkinson's disease. Thank you! Best wishes from Germany

[@raeblair6166]

Always so beneficial when learning complicated concepts.

[@naantube2073]

You are amazing at teaching, can’t believe my luck at coming across your channel. Thank you for sharing your expertise 🎉 truly remarkable 🎉

[@Whales-needustocare]

I love your memory and your passion! ROCK STAR!

[@robinkaczanowski7970]

Love this❤❤❤❤Need more! Excellent Teacher.

[@katarinatysse6086]

Thank you so much!!

[@chipochuumpu6602]

Thank you!

[@lizechard]

omg wow bc of you this made so much sense and ur repetitiveness did burn a hole in my brain so now I know the normal system of the tyrine turning lvdopa into dopamine etc etc. Thank you soo much for this , ur the best

[@eashaanwar9834]

Just awesome and time saving❤

[@mariapereiramd7173]

Thank you for this video!

[@GetvasTube-el5bl]

Ninja is the one of 21c scientist...♥♥♥♥♥♥♥♥♥♥

[@steveh1460]

Love your passion for teaching! Thank you!

[@moloreanm1657]

Nice vid! Now one about Huntington’s 😊

[@jessicasmith6873]

I remember voting for pharmacology videos many months ago. I don't want to complain but I relied heavily on you to passing anatomy and now that I'm in pharmacology I'm gonna need you to hurry up 😜 . We did Parkinson medications last week 😞

[@rajejyo]

A quick question...does ADR's in brain happens due to excess dopamine? as dopamine cannot cross BBB and if yes, then how does ADR's happens in mesolimbic pathway

[@NinjaNerdOfficial]

Great question. Any drug that increases synthesis of dopamine, prevents breakdown of dopamine can be utilized in dopaminergic pathways in the brain i.e mesocortical or Mesolimbic pathway etc

[@amine6005]

You are the best of all the time in saving med students life we are craving for more pharmacology

[@ashutoshsahoo1013]

Finally All concept clear 😌Salute to your Passion and Strength. Love from Odisha.

[@sangsenglay9989]

thank you so much sir, may god bless u

[@michaelibrahim7190]

The reason i will be a Pharmacist will be bc you exist! You are much loved in England

[@hadisehazizi3696]

Thank you helping me with my pharma exam😭😭😭😭😭😭❤❤❤

[@StellaJaeR]

very informative video, you are helping so many students and professionals

[@stephanieslay2976]

I can't thank you enough for this video 🙏 You're just awesome ❤

[@kirandeepkaur6265]

Great teaching process👍🏻👍🏻👍🏻👍🏻

[@hamsakm915]

Your amazing !! Love and prayers from India 😊

[@virginiabruno624]

You are intelligent you go deep into it

[@buombothmut]

A great scientist ever❤

[@solomebihon2218]

you are great God bless you the best teacher ever am medical student in east Africa Ethiopia

[@shreyaverma1699]

you are just LEGENDARY

[@norasaf7838]

The best Ph of medicine

[@NaseemBajwa-u1o]

Great video, very informative!

[@Abdullah_DS]

You know Zach that your vids are kind of entertainment!

[@ellionorader3219]

Thank uuuuu best teacher ever I used to follow You when the channel has some 70k so soproud that you ve reached the M You deserve mooooore

[@alishka0109]

love you zachy

[@kda-2672]

Thank you so much ninja nerd❤ you're a life saver

[@sianavassileva403]

great person truly

[@owaisahmed7653]

outstanding all the time best teacher❤

[@oscarpaz6162]

thank u so much for this video zach 🥰

[@laureenl6840]

Great video! It answered almost all of my questions. The only question remaining is, why is it so important for Parkinson’s disease drugs to be giving at specific times with little to no goodwill time? Does it have to do with the effective time?

[@monkearmy2216]

I really like these videos, hope you get more recognition

[@malikihamski4265]

Sir I appreciate your work Thank you so much A love from TANZANIA.......!

[@maryamzafar3379]

Hi, excellent video! single handedly getting students through medical school no doubt! I did just have a question: at 52:10 you said those dyskinesia side effects arose because you are causing too much stimulation of the indirect pathway, but since the indirect pathway inhibits unwanted motor movements, wouldn't INHIBITION rather than stimulation of this pathway pose problems? I really appreciate you answering:; thank you

[@sajiruddinsk8129]

Guru dev, Thank you so much, Jarur, Murshidabad WB India🇮🇳.

[@dindaire]

Omg thank you!! I take my PANCE in a few weeks and your videos are so good

[@s_l_m__]

Extraordinarily well made video. Thank you, Zach

[@NassebGo]

great as always ❤

[@enalakarim8589]

We love u here in zambia

[@brandoncoleman9576]

Absolutely love your work and appreciate what you do, I am an avid watcher of your paid site while I’m in FNP school. I would like to mention one thing, please find some other marker or remove the tops before you begin and stop clicking them on and off. It happens right at your mic and it becomes very annoying and distracting from your lectures which are so very important and would be amazing with less distraction like the caps constantly screeching….thanks!

[@goosey1055]

Excellent video.

[@jamiefootball2409]

cutest tutor out there xx

[@sumeraqasim7197]

Please make a video on anyipsychotic and anyidepressants

[@emacroitor1053]

thank you for your help! I am grateful! 😇

[@a5th_r]

Thank you very good doctor zach. But you didnt explain what ins the particular cause of tremor by acetylcholine... Where glutamate is desirable for increse desirable movement .. But why acetylcholine increase indesirable movement..athough the final pathway ot the movement in the cortex is decreased.. So how acetylcholine increase the undesirable movement?

[@doctor9410]

Man you are the only hope ❤️🤲

[@Chi-fk8gi]

You are incredible!

[@dailydoseofmedicinee]

Thanks

[@NishitaKinger-hr4ec]

Great Work!

[@uleeamadhila3419]

Dermatology sessions pls pls

[@AbeerEsam-p8k]

Amazing🎉🎉 Thanks 🎉🎉🎉

[@Astonishingmedico619]

Really amazing ❤❤!!

[@tolika7979]

Hello, I admire your job well done, it is very helpful for all of us! I watch you regularly and learn new things! Thanks! I'm doing a doctorate! I am looking for a connection between impaired understanding of human language, more precisely decoding, in patients with Parkinson's syndrome! What can it be, and where does it come from? Help!!! Be healthy and happy 🙂