Ovarian cancer: new preventive measures and recent data challenging decades of medical practice

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This clip is from episode 317 ‒ Reforming medicine: uncovering blind spots, challenging the norm, and embracing innovation with Marty Makary, M.D., M.P.H.
In this clip, they discuss:
- Can ovarian cancer originate in the fallopian tubes
- Preventive salpingectomy
- Resistances to adoption of new preventative measures for ovarian cancer
- And more
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The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 90 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more.
Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan.
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[@CallyNoon]

Women's medicine has been such a disappointment. Hopefully we are turning a corner now.

[@fuzzy7766]

"How was that not understood?" Answer: it only affects women (plus what he said)

[@keithinwr]

As someone who’s married to a five times Ovarian Cancer survivor I wish experts like this knew more about how important diet, exercise and certain supplements are in surviving Ovarian Cancer. I’ve learned a lot since her first diagnosis of level 3C in 1999.

[@andrewjohnstone7700]

Very interesting and potentially game-changing information, however the comment that 'damaging an ovary in a premenopausal woman' would be a 'disaster' might be a bit of an overstatement, particularly if we are counterbalancing the other risk being a cancer one in 80 women get that had a 50% mortality. Given that a fair number of physicians agree that postmenopausal bioidentical hormone replacement should be the default for most women, even if BOTH ovaries were to be damaged beyond repair, the consequence would essentially be starting BHRT perhaps at age 40 rather than 50. Not sure that 20-40 years of BHRT vs 10-30 years is a huge deal versus potential benefits of salpingectomy if the patient is already having elective abdominal or pelvic surgery.

[@daviddrake8742]

I am a gynecologist and trained under one of the greatest gyn oncologists and also trained under a great gyn pathologist. This information came out and the British Columbia studies occurred late in my career. It was an amazing observation and it instantly was a light being turned on. Wow! It did explain so much. Our practice turned toward the light. Great video!

[@davidmangen1912]

Gerson Therapy, wheat grass powder, moringa powder, matcha powder, apricot seeds(B-17), Essiac Tea, ivermectin and fenbendazole.

[@Hinz2005]

I lost my Grandmother to OC on 2/14/2024. She was a lovely human.

[@RosarioEmanueleDistefano]

This is not new! The precursor of ovarian cancer, known as STIC, has been recognized for a while. But if you remove just the tubes there is still a possibility that you can have ovarian cancer.

[@wendyhutchinson5820]

I live in East Tennessee and in 2017 I went in for a tubal ligation. My gynecologist recommended back then for me to go ahead and have the fallopian tubes removed altogether. I did and am happy with the decision. If they’re doing this in little ol’ Maryville Tennessee, why is this being recommended everywhere?

[@Hinz2005]

Same here in Alabama! Went for tubal but Dr. Miklic suggested removal.

[@perserverance333]

Pete is one of those outliers who looks good without hair.

[@natalierice6528]

This was fascinating. But how about a follow up on how we can prevent fallopian tube cancer (besides surgery) and what signs to look for at its earliest stages?

[@mcourbron]

Im a BRCA2 carrier and had a preventive salpingectomy 3yrs ago at 39. Did my own research and did not want to get a oopherectomy. Will be getting my ovaries removed closer to 50 at menopause. My OBGYN agreed this was a great risk reducing option for me given my age. Im on Vancouver island in Canada

[@Hinz2005]

I am non-BRCA, but lost my Grandmother to OC on 2/14/24. Soul crushing. Prior to her DX in 2019, I had elective salpingectomy in 2017. I asked to have tubal ligation, and my OB/GYN suggested salpingectomy to truly ensure sterilization. We had no idea what a gift this was!

[@mcourbron]

Good for you. I wasn't offered. Genetic counselor said double mastectomy 35-40 and oopherectomy/salpingectomy 40-45. I ended up doing my own research and falling upon these new findings that most ovarian C start in the tubes. It was a no-brainer for me. I called my family doctor and she hooked me up with OBGYN. I was fine with the DMX, not so much with dropping my ovaries b4 45yld

[@lorrilewis2178]

In 2020, an ultrasound showed my left ovary had multiple cysts and was blown up the size of a small cantaloupe and there was some issue with the fallopian tube. I then experienced ovarian torsion and was sent to an oncologist gynecologist. He knew immediately that I didn't have cancer, but the ovary had to come out. He said he was taking both fallopian tubes because ovarian cancer begins in the fallopian tubes. I was so shocked to find that out and immediately wished I'd had them taken out instead of the tubal ligation I'd had in the 1990s. I am curious about one thing though. There is an unofficial term "tubal ligation syndrome" and I definitely had it. I used to have heavy periods (high estrogen/low progesterone), but after I got the tubal ligation, they became even heavier and unbearably painful. I then got an endometrial ablation, which helped some. I've met other women who had the same side effect afterwards. I wonder if having the fallopian tubes removed would cause the same side effect as tubal ligation .

[@Hinz2005]

I experienced zero change in menstruation after salpingectomy.

[@lorrilewis2178]

@@Hinz2005 I don't think most people have issues after tubal ligation, but a sizeable number do. I just wondered if there would be a difference. I'm post-menopause, so thank goodness it's all over.

[@karlakay]

Um Wait. Were you saying that a 67yo W who WANTS to have her fallopian tubes Removed would Not be offered the procedure; couldn't get the removal as a way to reduce her risk of "Ovarian" cancer?? 😮 "After that the benefit diminishes" 13:10 WHY? If that is when Ovarian cancer is most common? Did you intend to say a hysterectomy is the 'standard of care' after a certain age, instead of removal of Only fallopian tubes ??

[@dawnwright8422]

So what causes fallopian tube cancer?

[@ruthannwhite6799]

THANK YOU for talking about this. It seems a subject no one wants to even touch. SO important for women to be aware of.

[@user-tv3vp8ji9e]

It was said that most people don’t know they have ovarian/fallopian cancer which is why it is deadly but if caught early there is a better chance at surviving. How would a person know if they are developing cancer? What are the signs or symptoms? I frequently have some pain in the left ovary area but gynecologist’s don’t seem concerned. Is it because there is no way to test for it and rather a wait and see approach which equates to imminent death? How long does it take for ovarian/fallopisn tube cancer to become deadly?

[@daveweil6767]

Very helpful information to share, thank you! Curious what you make of the literature on previous chlamydia infections, PID, and ovarian cancer risk.

[@appl314]

Very good information to know!

[@treehugger0105]

Shilling for Bill,pathetic.

[@JesusSaves7012]

?

[@blee3ee]

New rule: most crazy ideas are wrong

[@1timbarrett]

Which crazy idea do you have in mind…? 🤔

[@trtony-xe4cl]

Removing ovaries doesn't have to be a disaster, my 43 year old wife had this done & yes she badly suffered from immediate hot flashes/night sweats,/ bone pain,/ memory loss,but with daily berberine,curcumin,green tea,no carbs,high protein diet, B complex,vitamin d3 & k2,all symptoms subsided within 6 months

[@teodorakis309]

I have done salpingectomy for a while