Pharmacist Reacts to NileRed: Making Prescription Drug For Another 21 Minutes (PART 2)

[@InaYu2024]

This is my first EVER sponsored video and I am beyond thankful to each and every one of you. I am so grateful that I get to make content that not only makes me happy, but that you enjoy watching as well. My goal has always been to make entertaining and educational videos about medicine and I am trying my best everyday to improve on my skills. It has honestly given me a renewed sense of purpose and it feels really great to be striving for this goal. Appreciate you for being here

[@gh0st6762]

👏

[@BelleBell-k6u]

wow congratulations!!!!

[@psqlm457]

You deserve it! Congrats !!

[@RenVem]

Congratulations!

[@VihMelchior]

"Maybe someday i can do my first drug tier-list" oh my hahaha hey, I HIGHLY ADVISE you do not name thr video "drug tier list " 😂😂😂 omg I need that video

[@InaYu2024]

Yes that would make it incredibly sus 🤣

[@RonaldDonald-m7v]

​@@InaYu2024 but people would totally click on it 😅

[@yuningsun6914]

@@InaYu2024a KZbinr by the name ThatChemist does chemical tier lists that you may find interesting

[@xiaoyuhong8445]

I LOVE THIS INCREDIBLE IDEA HAHAHA

[@joelhahn2501]

Have you seen Derek Lowe's "Things I Won't Work With" series, on his "In the Pipeline" blog? It's all text, so is not very conducive to a YT reaction vid, but he's a medicinal chemist with a very dry sense of humor--and some of the eyebrow-raising stuff he describes makes anything NileRed does look like child's play. In particular, look for "Sand Won't Save You This Time"...

[@CrysResan]

"and prevent the formation of Phosgene." That is about the most alarming thing I have heard in my life said in the most monotone bored manner ever.

[@Simon-ho6ly]

phosgene pops up pretty often in organic chemisty, ive had about 40g of it cooled to a liquid in a reaction vessel before.. its scary yes but thats why handling and containment procedures exist

[@Refertech101]

Phosgene is pretty harmless compared to some of the stuff we have in our labs, like death powder.

[@The_Keeper]

@@Refertech101 **sigh** Alright, guess I'm gonna have to be the one to ask; What is "Death Powder"?

[@tadferd4340]

If you can reuse the glassware, the reaction is tame. When I worked in a petro chem analysis lab, there were definitely times where a sample was violently on fire. We just calmly extinguished it, and then checked if it was salvageable or if we needed a new sample. The worst incident was when a client took a gasoline sample. We didn't like clients taking samples themselves except for a few locations where we knew they knew what they were doing, and this incident demonstrated why. The sample gets delivered to us in the usual brown glass 1L bottles. There were about 12 bottles. We immediately notice that they are very full. To the cap or very close. This is very bad and 3 of us immediately start unscrewing the caps. Unfortunately one of the bottles shatters before we get to it. This was not in the fume hood. Fortunately it was near a back entrance. Gasoline has a high vapour pressure. Containers should not be filled more than 80%.

[@Zachary_Roemmich]

As a student who is starting an undergrad chemistry degree in the fall, I 100% agree with NileRed that Chromyl Chloride has the fun properties. The boring properties include colours, no boom, and stable. We like the dangerous stuff.

[@InaYu2024]

😳 never knew chemists were such thrill seekers until I discovered KZbin…!

[@C0lon0]

Nothing better than azydes

[@waltarb8573]

@@InaYu2024 Im just a hobby chemist but saw like actual chemists making tier lists of nerve agents so yeah...... wild people but amazing :')

[@kvikende]

"That Chemist" has some fun tier lists including some pharmacy and medicine related ones, like ranking carcinogens.

[@InaYu2024]

Thank you for recommending!

[@SylviusTheMad]

My Dad always kept a jug of diethyl ether in the garage. He used it to clean oil spots off the driveway (it would dissolve the oil and then the resulting stain was easily flammable and he could burn it off with a propane torch).

[@InaYu2024]

What a useful chemical, knocks people out AND cleans tough spots 😆

[@VihMelchior]

Already have sponsors? WOW! Congratulations! Your channel will be huge

[@InaYu2024]

THANKS FOR YOUR SUPPORT!! ❤️

[@Flamewarden_Honoushugoshin]

The mud/oil bath healing scene with Baron Harkonnen was actually new to the movies, and was Villeneuve's idea to imply the he was still severely injured by the poisoning attempt despite having escaped the worst of the gas by hovering near the ceiling with his suspensors (one of the attendant's mentions "he's still healing" when Raban goes to see the Baron after the assassination attempt). It was mostly done for the symbolic imagery though, combining the intimidating element of the Baron lurking beneath the mud's surface with the sickly substance with the appearance of black rot being metaphorically parallel to the stagnant conservative decay and oppressive nature of Harkonnen rule.

[@patheddles4004]

Fun example of a non-tame reaction on a watch glass. Can't remember the chemicals offhand, but it was two liquid reagents to make a compound that was being investigated as a potential rocket fuel (early days of US space program). One small drop of reagent A on the watch glass, one small drop of reagent B near it, and then the two were combined by remotely tilting the watch glass. The "remotely" part is important, because the reaction product immediately detonated and reduced the watch glass to a fine powder. (story paraphrased from the book "Ignition!", which is full of stuff like that from the early days of the US space program)

[@castform57]

9:54 Nigel described his pee as "nice golden liquid". This reminded me of a neat riddle in the game Noita. In that game there are a huge amount of different liquids and materials that react with each other, and a mysterious ancient group of people known as the alchemists. In some of the alchemists notes they describe "our gold", which turns out to be urine.

[@gh0st6762]

Surgery without anesthesia sounds like torture😨

[@InaYu2024]

It sure does 🥲 would not want to go through that

[@h.1699]

even after anesthesia were commonly used, in wartimes (or after huge natural disasters) sometimes there wasn't enough of it to use on soldiers and injured civilians, leading to surgical shortcuts (pun not intended) like rather quick amputations where in theory the limp could have been saved with a more extensive surgery to reduce the time operating and thus the potential for patients to go into pain induced shock and die. sure, it wasn't the only reason for it, but it is/was a common reason.

[@bandana_girl6507]

Surgery before anesthesia also ended up trying to be as quick as possible most times, with some surgeons being renowned for their speed (which reduced risk of other complications). Granted, that does also rely on good prep for the surgery, which was infamously an issue with one particular amputation performed by Dr. Robert Liston, "the fastest knife in the West End". He performed a leg amputation in under 2-and-a-half minutes but had also accidentally amputated his assistant's fingers. In addition, he slashed through the coat tails of a spectator. Both individuals who had received amputations died from gangrene (because it was also pre-Listerian) while the spectator died of fear-induced shock. So one patient, three deaths.

[@DeathBean89]

@@bandana_girl6507 this feels like the quintessential classic engineering dilemma: Fast, Cheap, and Good -- pick 2

[@afrog2666]

@@bandana_girl6507 Heh, I remember that story, pretty crazy stuff. "fear-induced shock" = heart attack I assume..

[@ranid0072]

0:19 it's from mock-up channel, who recreate Nigel's voice through AI and.... I think that video originally not available, but reuploads exsists

[@De_Vliegende_Hollander]

In my country the first anesthesized surgeries were done in the early 1600’s so way before chloroform and diethylether. Guess what they used as a sedative? A big bottle of alcohol… and if you were rich you could get Chinese opium. So no, the first surgeries were done waaaay before you Americans have learned. I imagine the Chinese and Persians doing it way before the Dutch. So Europeans weren’t the first to do so. Even the ancient Persians are supposed to have done surgeries like removing arrows from brains and other organs with the help of the papaver somnium/somnifera. Aka good old opium.

[@ChibiQilin]

It's really interesting, having watched these videos before, to rewatch it again but getting commentary and explanations like this. Love the work.

[@wyvren_]

I'd honestly binge watch a tierlist, this is really good content and it honestly is always fun to watch your videos!

[@InaYu2024]

Thanks for your support!!! ❤️

[@chrisp33]

It was mild. The watch glass even stayed intact.

[@DimiDzi]

knowing what he does "tame" is a good description for that reaction

[@devinnewbyart]

EVERYBODY WAKE UP! New Ina Yu video just dropped! Yay! Love all your videos! Nilered is great, but I love all of your educational add ons. They're always so informative and entertaining! Oh and congrats on your first sponsor!!! Keep up the good work!

[@InaYu2024]

Thank you so much for your support!!! ❤️

[@etchatails]

This is my new favourite channel

[@InaYu2024]

Welcome! 🤗

[@RandomGuy0987]

Actually I don't see the sponsor link in the description. Old nilered videos are nostalgic, you can see how much better he got at making videos. :)

[@InaYu2024]

Oh no I am the worst 😭 it’s there now thanks for the reminder!

[@RandomGuy0987]

@@InaYu2024 I bought the manta sleep mask, my first impression is works, total blackout and it's not a cheap piece of garbage. Nice sponsor.

[@Merrsharr]

Actually, medieval surgeons used opium as anesthetic long before the invention of the surgical theatre. This had a high risks for the patient, so they rarely used it. Diethyl ether may have been known as early as the 8th century, but apparently hasn't been discovered to be analgesic until the 16th century.

[@Naztash]

I would argue that the most famous non-anaesthetic surgery, was the one done in the early 1800s by Robert Liston, which had a 300% mortality rate. He amputated a leg in under two and a half minutes, but due to the speed he also cut into the fingers of one assistant(who died from gangrene), and a cut through the clothes of a spectator(who fainted and apparently died of shock(or potentially hitting his head from the fall)), the patient also died from gangrene.

[@hamzacanyavuz]

Great video as always

[@InaYu2024]

Glad you enjoy it 😃

[@TarnishedTom]

Why do I feel like sleeping on your couch wasn't a bit for the ad? xD

[@InaYu2024]

I’m just a REALLY good actor 🙃

[@BDFireFist]

violent chemical making huh, I've seen 3 German chemists make potassium in bulk, ya it was entertaining to watch the chaos unfold.

[@alfimelfissa]

Yes please. Make a drug tierlist video! :D

[@canmex9422]

ya, his older videos were a lot more adventurous; quite the dedicatio to unearth a medical journal from 1875, and yeah i think chloroform is quite hard to dose so a lot of related deaths. Strange that the population still sees chloroform mostly as a knock out drug, simply because its portraied in movies this way

[@h.1699]

especially as it can take MINUTES for a WILLING patient to lose consciousness using chloroform... and even when dosed perfectly has some nasty side effects... using chloroform to knock out anyone struggling against it or actively trying to not breathe in the stuff is not a viable route, purely a hollywood myth like exploding cars...

[@InaYu2024]

Yeah the history was so fascinating!

[@blondejohn25]

20:44 "what's considered violent in his books?" my guess is the tsar bomba

[@Telogor]

"It's toxic, carcinogenic, highly corrosive, and potentially explosive." Of course that's what a chemist means by "fun properties".

[@Barty.Crowell]

"and urea... dangerous compounds" and yet I legally have to fill up my car with urea

[@Kenjuudo]

8:09 "Living organisms are fundamentally different from *non-living organisms*" Riiight... 😄

[@rockdc132]

Love you're vids and the hard work you put in to them and work a full time job witch has inspire me to seek more help with health things to be able to do what I love doing and start to live a better life but im sooo down to see that sus drug tier list one day hahahaha.

[@InaYu2024]

Thank you for your support!! ❤️

[@FireTrye]

Just found this channel! Amazing!

[@MSPaintRose]

Your reactions and commentary are the best it has ever been. Keep up the good work

[@InaYu2024]

Hehe thank you!! ☺️

[@dudexx4317]

10:37 omg did you pause here on purpose 😩😩

[@InaYu2024]

Not on purpose!!!! 🤣

[@thedeadmoneyallstars]

Ask a chemist to describe TNT exploding and it'll probably start with "vigorous exothermic reaction" 😂 I'm pretty sure it's a conspiracy to make it sound like a boring subject while they keep all the fun reactions for themselves!

[@Janayoonie98]

I really like watching your videos !❤

[@InaYu2024]

Glad you enjoy them!! ❤️

[@marshmallowblaster]

When are you going to fly to Montreal to collab with Nigel? Y'all need to make some common drugs together.

[@InaYu2024]

Omggg that sounds like it’d be fun!! 😆

[@marshmallowblaster]

@@InaYu2024 y'all could make some really terrifying poison and then make the antidote 🤣

[@BelleBell-k6u]

Drug tierlist video would be great 👍 ❤

[@wizardfelix4962]

As a pharmacist do you have any other tips or recommendations like the hydrogen peroxide one. I’m not so good at taking care of myself 😅

[@h.1699]

schedule routine checkups with your general physician... get to know your body's default temperature, pulse, etc to have a baseline to reference, when something feels off, and with routine in taking those measurements you reduce the influence of taking them on the final measurements... don't use duct tape on wounds...

[@InaYu2024]

The number one tip is go talk to your pharmacist they know a lot! 😃

[@crashmatrix]

Oh heck yeah, a drug tier list would be welcome very much

[@autohmae]

7:14 this reminds me of early ways to diagnose diabetes, etc.

[@konekoray9323]

i would love to see a reaction to the follow-up video where he did the cleanup after the chromyl chloride

[@2Cerealbox]

There is a chemist who ranked his favorite nerve agents.

[@MysteryKar]

if you want to see a violent reaction i recommend the video "NCl3: a terrifying yellow abomination" by Explosions&Fire, which incidentally also has nilered in it near the end to answer some urine related questions so it is a spiritual sequel in a sense

[@h.1699]

it basically just produced a flame, that's pretty tame for a potentially explosive reaction

[@jovazquez6102]

I love your Dune references btw! Definitely looked like a pile of melange 😁

[@InaYu2024]

YAH I’m glad you think so too! 😆

[@theoakun3635]

for a less tame chemical reaction i wouls reccomend his: This chemical really doesn't want to exist.

[@autohmae]

I've seen eating lots of red beets also turns pee color red, so yeah, probably ask that too 🙂

[@albertcanda9181]

I was actually thinking that he would try to taste that 😅

[@Refertech101]

Nitroglycerin is a fun one, especially when you taste that pleasant ethereal sweetness on the lip from a random drip flung off some how, And to the espresso machine I go to make the strongest coffe humanly possible then proceed to turn off any thing that makes noise and or light and settle down for a very miserable night!

[@andrearaimondi882]

You should definitely make a collab with Nile, he’s in Canada as well!

[@InaYu2024]

That sounds like it’d be so cool 😆

[@LinkageAX]

20:00 - this song reminds me of the ys soundtrack

[@Sujiyaru]

" nice golden liquid " ^^

[@InaYu2024]

^^|||

[@stonent]

Another group of chemicals with all the fun properties are Mercury Fulminate and Silver Fulminate. They're as toxic as cyanides and explosive that can go off under the pressure of their own weight in some cases.

[@jchan2888]

I'd like to get your take on Nile "Making the stinkest chemical known to man"

[@CyanDumBell_MC]

20:42 he did made a chemical that explode/combust on any contact once it dried I forgot what the chemical called

[@NKG416]

speaking of chloroform, my college classmate actually tried to sniff it. she had nasty headache and went to the infirmary

[@Konnor-LesleyOmijie]

Hey, I know this isn't something you can contrtol since they're auto generated for your video, but the captions when you say Nigel say the old fashioned N word, you might want to look at maybe creating you're own subtitles for videos so that ppl don't get the wrong idea, anyways, love your videos, keep up the good work!

[@NumbGeek]

Ever thought about watching some of Hamilton's Pharmacopeia episodes? They're incredibly fascinating

[@hugofriberg3445]

You should invite Nile to work a day in the pharmacy (almost like uncle rogers food truck video) 😅

[@InaYu2024]

HAHA that’d be so funny 😆

[@air9227]

you should watch styropyros video on an old chemistry book 😭 could be very interesting

[@stuntmonkey00]

It's hard to describe the struggle of modern floor to ceiling condo windows, crummy blinds and the really late sundown times in Canadian summers....

[@InaYu2024]

Yes the blinds basically do nothing 🥲

[@nokinirus]

Gosh I deal with alot of Chromium at work... I wonder how much of it is in my blood.

[@bknesheim]

Plastic can be converted to candy. 🙂

[@Refertech101]

they are not that dangerous, I make a lot of those things regularly in my lab as well, I use calcium Hypochlorite though as way less fluid volume to deal with. It is post processing is a pain due tot he washing stages to purify it, then distill and stabilize with 1% methanol. I use amber glass, I have 500ml of it, did have 1L but used a good bit of it.

[@windhelmguard5295]

ÎIRC the standard procedure for surgeries was to just get the patient drunk enough to pass out.

[@jacobyoung7018]

Wait, she didn't show the final urea product. Only the dried proteins and minerals from the urine.

[@lexitadeo]

wow!!! i love nilered

[@InaYu2024]

☺️☺️

[@dacomputernerd4096]

If I recall correctly, the liquid the Baron was in in Dune was some sort of healing bath to help the Baron recover from the poison the Duke blew at him while captured

[@InaYu2024]

Oh right!! Haha I feel like he was just in the bath 85% of the movie 😅

[@dacomputernerd4096]

@@InaYu2024 he was in the book, too. The first scene I recall him being described as out of it is the final palace scenes

[@Xnoob545]

5:58 phosgene is insane

[@tsume_akuma8321]

I know this is a bit rude, but I actually used to have a similar issue regarding my sleep. The way I fixed it was with a BDSM Blindfold though.

[@atzincastellanos6778]

girl is a giant fan of NileRed and doesn't want us to find out....but you do seem to get a kick in views but your ensight is so good, thank you

[@InaYu2024]

HAHAH 🫣

[@firefly618]

Thank you for the video, it was fun and informative! Nigel (NileRed) is very passionate about chemistry and he seems to have an intuitive, innate understanding of it and of the safety limits of the substances he handles. That probably comes from studying and experimenting with chemistry since he was a kid. That being said, I'm always mindful of giving attention and views to people doing dangerous things online. If you think about it, just by watching or sharing a video, you are directly financing that person and signalling them that you would like more of the thing you just watched. If that activity is dangerous or harmful to themselves or others, you are being an indirect accomplice. Not legally, of course, but morally so. This also goes for watching p****graphy and other kinds of exploitative content, whether you are paying for it directly or indirectly through ads/exposure/views. Just something to keep in mind. But NileRed is awesome and seems to know what he is doing, so he's A-ok!

[@InaYu2024]

Thank you!😊

[@nepaligamers8035]

ngl I just came here to watch her see her reaction to pee to urea part

[@dudexx4317]

6:16 could you please make a vid about Cocaine?? I would LOVE to know more about cocaine as anesthesia 😮😮

[@InaYu2024]

I can but KZbin will hate it for sure 😳

[@KrossX]

NileGreen next please.

[@petrsmid54]

4:22 top 5 things that never happened

[@AxionSmurf]

You like looking at old medical books too? My favorite is from the late 1700s to the late 1800s. I use Google Books to find them. It's like actual monkeys were doing medicine back then. I don't get caught up in the suffering people must have endured for a very silly treatment. I think it's funny that these people were considered doctors but they really had no idea what the hell they were doing.

[@InaYu2024]

Yeah I love reading old medical practices cuz they are just SO unimaginable bizarre 😅 it’s a completely different belief system back then

[@Jake-fq6ir]

here have some leeches your humors are off

[@tsingtak642]

16:13 My favorous medicine is thalidomide

[@InaYu2024]

We actually use these to treat cancer.. 😳

[@tsingtak642]

@@InaYu2024 this drug plays both roles of devil and angel

[@marsrevolutionary]

Built in closed captions on a platform that includes closed captioning? This isn't TikTok. Don't bake it into the video.

[@aligasgc694]

I like you please keep going ❤❤❤❤

[@blstcblender190]

congrats on the sponsor, well deserved

[@InaYu2024]

Thank you so much! 😊

[@xxxxxxxxxx9496]

Reached 10k🎉

[@InaYu2024]

YAAAS thank you!! ☺️

[@FinancewithXibaobao]

Mah drug de….I mean Pharmacist.

[@InaYu2024]

😆

[@fusion1203]

Do you actually have a real medical licence?

[@h.1699]

depending on the country pharmacists could count as having a type of medical license or be completely seperate from it. where i live pharmacology is studied the same way as medicine but it's not identical, significantly more practical chemistry and less anatomy/autopsy. in addition there are professions around those fields that do not require an university degree for example in drug production or nursing or several forms of technical assistance.

[@zachariahstovall1744]

have you ever thought about body building? you have a good build for it?

[@InaYu2024]

I haven’t! 🤔

[@zachariahstovall1744]

@@InaYu2024 you have a perfect foundation for it and it's amazing for long term health! it's a perfect hobby. you learn a lot about yourself in the gym.

[@Asdayasman]

Aren't ALL anæsthesias incredibly dangerous and put you on death's doorstep? Hence anæsthesiologists making the big bucks.

[@KaitouKaiju]

Yeah nobody wants the anesthesiologist to have a stressful day and slip a little bit too much in

[@goldenfish5390]

In 1 year: Reacting to NileRed making uranium cream and testing it.

[@InaYu2024]

That sounds like it’ll melt my skin 🥲

[@kramermccabe8601]

Kidney stones can make your urine red too.

[@voidseeker4394]

That would also be blood from the irritation and scratches from the stones. But yeah, if kidneys leak enough blood to make pee visibly fed, i'd call it urgent medical condition that requires medical help.

[@bobbycool2815]

be honest are u an industry plant