Pharmacology - Chemotherapy agents (MOA, Alkalating, antimetabolites, topoisomerase, antimitotic )

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[@ilen3820]

Im too stupid for this

[@dr.chris8]

😂😂

[@Potatocat5]

Same

[@Potatocat5]

Same

[@bushraquadri6974]

😂😂😂

[@perspicacity_impeccable]

Especially one hour before exam

[@preciousogie9852]

You just covered a two hour lecture in 14 mins. God bless you

[@AmruMagdy]

HBB gene 🧬 biological treatment honey 👌🦚🐝😂❤

[@mamiejatukanneh6563]

You have no idea, how many lives of medical students you are saving😊😢🎉🎉

[@haymaroo3577]

Clear to understand.looking forward to more topic about pharmacology .

[@cindyr1980]

I can't thank you enough! Your videos helped me through nursing school 5 years ago, and are now helping me with my Oncology certification, this is clear concise and to the point!

[@tkhan2392]

Hey Armando.. Thanks for the great video! Is there any way I can get a printout of this drawing?

[@Aesthetics.Torres]

Very helpful!! 🙂 Even for the clear and succinct explanation of the cell cycle!! Pay attention people!! 🧐🙏 Great presentation. Thanks!

[@simrakhan5263]

OMG THIS SAVED MY ASS. I’ve exam tom. 😂

[@WinterExplains]

4:44 is when he starts talking about alkylating agents

[@529ash]

Thank you!!

[@aleenazyt]

awesome video to go through before starting a chapter. simple wording explaining all the relevant details. 14 mins and you are done😊💖

[@Aya-sp6xe]

thx brother for beutiful explaination - i ask about the following video which u had remined in the last minute about hormones for treatment of cancer and side effect of drugs can i where find it ?

[@brcarter1111]

In recent years, the discovery of cancer stem cells has revolutionized our understanding of this disease. It has long been known there is incredible heterogeneity in a tumor, and now it seems these dangerous cells that often resemble pluripotent stem cells sit at the top of the hierarchy. It now seems apparent this small subpopulation of cells is crucial to the self proliferation, self renewal, refraction to treatment, and most importantly metastasis that characterize cancer as a disease. Some studies have shown that 1 in 400,000 non-stem cancer cells may undergo EMT and tumorigeneses (metastasis), compared to 1 in 7 of these cancer stem cells. As stem cells, they are incredibly robust cells that are difficult to kill, since their survival is crucial to the survival of our species and are forcing us to rethink our understanding and treatment of cancer. It was shown in one study that this small population of cells are nearly immune to chemotherapeutic treatment and highly resistant to ionizing radiation. As the scientists applied chemotherapeutic treatment to tumors in vivo, the proportion of cancer stem cells that was originally about 2% of the cells in the tumor became over 20%, suggesting that the treatment was killing the "bulk" tumor cells that are incapable of metastasis and selecting for the survival of these far more dangerous cells. They are immunologically privileged, employ drug efflux pumps to remove chemotherapeutic agents, and have constituitively active DNA repair mechanisms (contrary to the believe repair mechanisms fail in all cancer cells) that protect from radiation induced damage. We measure drug efficacy in oncology almost solely upon the principle of tumor remission, or the shrinking of a tumor in size after treatment. Again, evidence is mounting that suggests we are selecting for the survival of these cells and initial remissions represent the death of cancer cells that are not stem cells and therefore largely incapable of metastasis. To all the future physicians, researchers, and oncologists out there reading this, you must be aware of these robust and dangerous cells, and I challenge you to find new ways to specifically target and destroy them.

[@marabanara]

This is incredible! Thank you so much for creating this. I’m struggling through my chemotherapy administration training as a RN, and this really helps get an overview of the modes of action of the major groups. Thanks again!!

[@wonderworksauto]

Thank you Satanic Matrix Awareness for having the Balls to post this video! Kill Chemo Doctors Song 🔥 kzbin.info/www/bejne/g4LJiJaGnqiWmZo

[@humanoftoday1822]

We need teachers like you so that learning is never boring, Thankyou for such amazing videos with great artwork that keeps me motivated through out the time.

[@israkhattab1890]

Your drawings are magic

[@DeTrOiTXX12]

Awesome work, I very much enjoy watching your videos!

[@driffat100]

Hey, Armando, your way of explanation such difficult concepts is superb. indeed very helpful for meds students easy to remember and full of knowledge material appreciated and regards

[@shahifaaudyrahima2794]

thankyouu, this 14-minutes video beats the whole 2 hours of my lecturer explanations!!

[@maryjune2496]

Before I ask anything, your videos have helped me a lot with my essay about chemotherapy, so thank you for that! However, one youtube video isn't much of a source and I find it hard to find good scientific sources who go by the basics before getting specific. I see the link in the descriptions, but do you perhaps have a list with papers/chapters you've used?

[@AshokKumar-kw1hu]

Your diagrams are magical, made understand everything........

[@JP-wx6uh]

Gene therapy is the way to go, but we're so far away still. Using these kinds of highly toxic compounds are really not the best way to treat, but it's all we've got for now.

[@pd28samikshawanare73]

Hey, I am thankful! I cant thank you more. Your vedios really made this difficult topic seem easy. And these drawings provided me a vision to understand concepts and visualize answers during exam. I hope you make a second vedio of this anticancer agents part 2.

[@ماضيهاحنيف]

at 10:46 i almost thought that my laptop hanged up ... 😅 btw your lectures saves us from big thick textbooks revision

[@virnan]

Once again I've come to The Master's Page for succinct and lucid clarification.

[@gufengxu5485]

The best anticancer medicine video!

[@oncotv3779]

Thank you very much. Very useful and necessary information.👍

[@michaelalaimo3169]

I'm already familiar with the categories of chemotherapeutic drugs, but this video does an incredible job of drilling down to the details of the mechanisms of action. Bravo!!

[@amnanisarm.phil.scholardep8493]

Y anticancer drugs do not target normal cells? Like if an alkylating agent is used...y it do not alkylate all DNA of human body?

[@sadiarahim1453]

CRYSTAL CLEAR EXPLANATION OF ANTICANCER AGENTS!💞

[@zulaikharozman29]

I have watched this video at least 15 times. Thanks you so much, excellent explanation. Just wondering if the video on hormonal agents was ever made?

[@the.basicDr.muskan]

Just luv u videos ....So helpful ..Luv from india 💖💖💖

[@tarunkumarpalli7580]

Do this therapy will effect to normal cell which under go cell division, apart from cancer cell

[@aleenamahvish2451]

I have been a subscriber for a long time now,and your work is impressive you are an amazing teacher!!Congratulations for 1M+ subscribers

[@s902532002]

I have to say: Thank you very much.

[@divyajoshi5496]

Does chemotherapy works for actively proliferating cells or does it reduces % of cancerous cells? Hope to see your ans asap

[@airbender9593]

Do you have a full image of what you wrote? At the end of the video, the bottom portion of the image was cut off.

[@Sage-hl5ir]

What an incredible video bro.

[@laurajjthomas]

Do you have this concept map that you are making in this video for sale.

[@kaungsithusett9017]

you say terygoid, not pterygoid. apo-ptosis, but it's pronounced apo-tosis!

[@prakash4491]

Such a beautiful lecture 👏👏loved it

[@sravanabburi8481]

Oh my god 🔥 you are just insane sirr ✨

[@daneliaz1296]

I love your work , we need more courses in oncology like that

[@tovs716]

You helped me so much! Thank you!!! You're so clear and succinct.

[@DrBENISA]

Sir god bless you with all its glory 😂 For real, so much made sense to me after watching this

[@ranveerkashyap6459]

Very clear and doubtfree video on Chemotherapy.

[@kanchanbhamare899]

It's a trually an amazing vdo with literally simple and very understanding concept ....Thanku so much for making it interesting...

[@charafeddine7095]

You're one of a kind, thanks your video really helped me a lot to understand many things in my lesson

[@JUrb1000]

little correction: Adenine, Guanine,.... are not nucleotides, they are bases. AMP, GMP,... are the nucleotides.

[@attibarizwan8994]

Always You have a solution for confusions MaShaAllah. Continue your work . Best of luck for future. InShAllah you will get best reward

[@islamadel9507]

Wooow thanks for that effort. Its impressive ❤️🌹

[@spiritual594]

One of the best pharmacology video I ever seen ty so much...

[@donovanlucibello379]

More of that, please! Anyway to download that graphic that you made over the video? Thanks in advance

[@zakendi8244]

I was wondering If a cell is replicating, does it (the cell) do its other jobs like producing proteins and hormones and receptors. Or does it just stop in all the fields ??? thank you very much for this video Armando

[@BabblingForever]

I think the cell pauses all of it's "normal" functions during mitosis. Interphase is the period where a cell continues with acquisition of nutrients, metabolism etc. The majority of a cell's life is spent in interphase.

[@readmails3033]

Thank you, you are an amazing teacher and a brilliant illustrator.

[@khashayarmastoori]

IT COULDN'T BE MORE CLEAR

[@dawoodibrahim287]

Easy to understand and clearly explained

[@PeaceNinja007]

Did you really draw all that? .. it's really good

[@adityapandhare1484]

Very help ful video 📹 thank you ❤

[@Noo7aNemo]

Thank much!!! You don't know how much you facilitate the process for us, please going (Y)

[@vishwarajdeoda1510]

The video was too fast... 😢

[@SlanderMonkey]

The link in all your descriptions (/dig) still doesnt work: "It looks like the page you are looking for does not exist."

[@Rahul31102]

👍

[@mharmhee2560]

Thank you so much. I’m a new grad nurse and assigned in Oncology, this saved me a lot.

[@rukiee.b.ovwigho5709]

Very clear and wonderful video. Thanks a lot Armando 👏👏👏👏

[@putrivenn1446]

THANKYOU SO MUCH! IT'S REALLY HEPLINGFULL

[@snehamotavar6664]

Best one! Thankyou 😊

[@franca6543]

Thank you so much...Waiting to see how these haters will teach us one day for free... be grateful for once gosh😯

[@thurraiyahahmed9074]

Thank you soooo much🫶🏽🫶🏽🫶🏽❤❤❤

[@th3awsom3]

GREAT VIDEO! THANKS :)

[@priyankapatil1543]

Thank you for clarifying mechanism of action within short period of time.

[@Iamspoorthiii]

This helped a lot for understanding antineoplastic agents. Thankyou ✨

[@supriyashukla2321]

Thankyou so much for making it so easy. :)

[@mandardeodhar400]

Very well explained. Thank you very much

[@rashidfarhath8967]

Bro make little bit slow..why so much speed

[@sukhendupramanick1661]

Totally helpful... But, I think small mistake is there, it's alkylating agents not alkalating...thank you.

[@dr.amw11]

Thank you so much sir!

[@ajayunagar907]

Thank you so much .... it's video making ..in all steps clear to understands...and succinctly

[@poonamsohu7883]

Thank you so much....it really helped 😊

[@dr.bhagyshrilandage74]

Very nicely explained .. it's very difficult topic but u cleared all concepts thanks a lot.

[@aayushiborkar3213]

Thank you universe

[@muhammadfasieh4757]

Online classes suck but this here cleared my concepts😀❤️❤️

[@jabu003]

Thanks , it would very usefulll for many of us if you can kake a video on CLL

[@Artem_Shipov]

3:32 Damn. This is hard to comprehend 😕 But, the presentation is awesome 👍

[@joitatonchanga1308]

Thank you very very much.

[@IsabelRodriguez-nv2ue]

Amazing presentation! Thanks for creating it. Truly helpful!

[@charlesmanakpalah7773]

This video is very amazing and easy to understand.

[@meghasa8416]

Wow! I finally understood these :) Thank you so much :) Your videos are amazing 💜

[@dr.rameanasibaranind3549]

Very helpful. Thank you so much!😍

[@redlips1309]

This is really helpful. BIG THANKS!

[@hanaineu]

Excuse me, I dont get the function of methylene THF. To make dTMP, its only need thymidylate synthase, right?

[@souadachtouk1452]

THANKKK YOOUU SOO MUUCHH

[@BigBossHuntelaar]

Is the video about chemotherapy side effects still to come? I haven't found it between your YT content

[@hdh2179]

thank you great job

[@htoonandar6557]

it's so easy to understand...thz u so much

[@sravanabburi8481]

Love from india ❤️

[@IsabelRodriguez-nv2ue]

Great video & illustrations that really help in understanding these complex concepts. Thanks a million!!!!

[@michellebutterchew3678]

This is wonderful. Thank you!

[@summernilo7358]

Thank you! Your illustrations are always great and you speak clearly that's easy to understand!

[@TasnimAnwar]

Great video. Thank you.

[@nandinichahal2537]

Great video, thank you!