Why is detector wavelength considered, when it is not allowed to change?
@sanketdalvi29422 жыл бұрын
thanks sir...❤️
@PharmaPill2 жыл бұрын
Most welcome
@trendbizz2743 Жыл бұрын
Why need to adjust these parameters means in which situations need to do this
@PharmaPill Жыл бұрын
because exact methods mentioned in monographs are not able to give results… so we need to optimise our method within mentioned limits of USP621
@manojmodi414 Жыл бұрын
New chang
@rahulchaudhari2023 Жыл бұрын
Partical size no increase this point not highlighted in USP chapter
@ajitjadhav6072 жыл бұрын
Dear sir, if in HPLC method gives dual wavelength detection, for IMP 3 at 210 nm & for IMP 1 & 2 at 230 nm. For purity, single imp and total imp no specific wavelength (210 nm or 230 nm) given. Then at which wavelength we can calculate purity, single imp & how we can calculate total imp? Pl guide sir
@PharmaPill2 жыл бұрын
don’t know
@chinnabotta3988 Жыл бұрын
You have extract standard and impurity respective same wavelength then calculate
@ajitjadhav6072 жыл бұрын
sir If we adjust the chromatographic parameters then it affects in RT which is mentioned on pharmacopeia then how we can put a remark on it ?
@PharmaPill2 жыл бұрын
ideally their should be a note point in your STP as well related adjustment whichever you are going to do.
@manojmodi414 Жыл бұрын
Sir, request for New change 621 USP
@ajitjadhav6072 жыл бұрын
Is any chromatographic parameters adjustments are given in EP or BP. Kindly share as well as share general chapter no. for references.
@PharmaPill2 жыл бұрын
okay
@harshalchaudhari94882 жыл бұрын
Younot mention the mobile phase ratio adjustment for ternery mixture