"Pill in Pocket" - Anticoagulation for Atrial Fibrillation (Drs. Rod Passman, Miguel Valderrabano)

[@charlenebutler9076]

BRAVO for the exemplary scientific thinking and openness to challenging the status quo. PLUS the high quality evidence based research. Your presentation answers all the questions I have been having and unable to get any doctor to engage with.

[@Mark_Ocain]

Excellent presentation. I will share this with my Cardiologist (an A/Professor at our regional Uni) I think he'll enjoy this too. I think he is already aware of these strands of thought.

[@starbucksk2]

Very concerned that this has not received more attention and comments. The new digital wearables and devices can finally answer a lot of questions about afib tratment. This Doctor needs strong support for completing his study which is based on the most up to date thought.

[@CathyBInAGaddaDaVegan]

this describes me, no stroke risk but am on anticoagulants daily after one 6 hour event, four months ago. have a kardia card and fitbit and havent seen a single event since. meanwhile the anticoagulant prevents me from taking NSAIDS for arthritis so im in pain. im only 58. i dont wear a raincoat all the time just because it rains sometimes. very frustrated.

[@dougcoleburn1579]

Agree I’m 52 male with a score of zero and Dr wants me on Eliquis 24/7.

[@carolinem.9800]

in my city, those with a CHADv of 2 or 3 are being rx d both an anticoagulant and a beta blocker 'for life'--even if the a fib is asymptomatic and of short 1/2 hour duration 1x a year. . I anxiously await the result of your study because I hate the notion of being on anticoacs and b1 blockers for life when I could take anticoags only for 30 days.

[@michelehyde3991]

Thank you for sharing

[@billv4072]

If the majority of cardio induced stroke risk originates in the right atrial appendage, why isn't that the focus of afib stroke prevention? Watchman device implanted through the leg or appendage clip to clamp it off through minimally invasive surgery? I'm in persistent afib with a zero Chads score and have a Wolf Mini Maze surgery scheduled for October. Fix the problem, don't just "treat" it. NOACs are expensive and have life threatening side effects. IMHO more young cardiac surgeons should be waiting in line to train under Dr. Wolf while he is still operating on patients.

[@starbucksk2]

This approach could eliminate the risk of the watchman procedure and almost eliminate the noac risk by reducing the need for it

[@billv4072]

@@starbucksk2 Maybe for periodic episodes of afib phone/watch/NOACs could work? I was in the original Apple watch Afib monitoring trails (because I have constant Afib). With my Afib the phone would be alerting me 24/7, so I'm going to have Dr. Wolf clamp the appendage off and work his "magic" on my nerve bundles on the outside of my heart.

[@starbucksk2]

@@billv4072 I wish you well with that and hope you somehow can keep people like me in the loop. I had a transthoracic aortic valve done which seems to have caused some afib and arrythmias. I am on Eliquis noac and a beta blocker. I make a concerted effort to avoid the suspected causes and have a low chads score and very seldom have episodes of afib but a lot of arrythmias. I have a watch and a ecg interpeter service online. The medical science seems to have difficulty with this whole area probably because of the intermittant nature of afib. If I get what you have I would be interested in the Maze procedure as well. This pill in the pocket based on digital analyses finally looks like modern medicine to me. Take care

[@robertporter1429]

Billy….I agree totally…I am at thi moment trying to get in Dr Wolfs pipeline….I am 100% behind his approach!

[@JKerr-iy2jr]

Samsung produces a smartwatch that offers Android users most of the same data as the Apple Watch. I check my AFIB/ heart rate data several times a day so there isn’t necessarily a digital divide between Apple/Android users. The main obstacles to much of this technology is FDA approval, not technical development by the tech firms.

[@josephbuser4403]

Regarding the study, do you have any estimates on when it will conclude? thank you

[@RodPassman]

2027

[@josephbuser4403]

My cardiologist made me aware of this study. I'm really excited to hear how it goes. In the meantime, could someone tell me what app participants are using to monitor for AFib? I use the apple watch v8 that has a montoring app but if this group is using a different app I would like to get it and use it for my own monitoring. Thanks

[@RodPassman]

The AF detection algorithm used in React-Af is customized for this study and is not commercially available.

[@omhhola8844]

What about if the patient has a synthetic valve?

[@KimWentworth-y8e]

24 hours over what time period. Need that factor. Is it 24 your of afib in a week, month or year.

[@gusmath1001]

Is the apple app used for monitoring the study participant available to non participants. If not, why not?

[@josephbuser4403]

Great question. If it runs on the iwatch, it should be in their app store. Does anyone know the name of the app that's being used in the study?

[@KimWentworth-y8e]

Again you need to define the time period. Less than 24 hours of AFIB in a year, month. There are missing parameters.

[@davidmarilley6060]

So you are at Debakey, the home of MINIMAZE and you talk about not having afib efficacy? Lol