Polycystic Ovarian Syndrome (PCOS) - Pathophysiology, Symptoms, Treatment

This video thoroughly discusses the pathophysiology of PCOS and also includes manifestations and treatment. It can cause a vicious cycle with increased androgens and increased insulin/insulin resistance.

[@ImNotFromThisPlanet]

Amazing how you got Pedro Pascal to narrate this video. All jokes aside, amazing explanation and video.

[@rayanyassin2371]

Thank you so much I've lost count of how many times I tried to understand PCOS and it finally makes sense thanks to you! ❤

[@gemstonerose4648]

For sth that has been happening to my own body for over half my life, its amazing to finally understand the exact reasons of it. Thank you!

[@debigdogk9563]

ONLY A GENIUS like you can deliver such an extraordinary teaching skills. GOD BLESS YOU FOR THIS WONDER JOB. ❤❤❤❤❤

[@physiopathopharmaco4190]

Wow, thank you

[@labs2798]

I was struggling to understand this topic so much. This video made it super easy! Great work

[@Niyati_sankhe]

You made it so easy for me to understand...thanks a lot for such great explaination & video too ♥️

[@iialxvc]

We’re goin to medical school with this one 🗣🗣🗣‼️‼️‼️

[@vaishnavikhare8596]

i m no med student, i just came here to understand whats happening in body. Thanks sir !

[@pfvxuxu]

Best video about Pcos and IR available in you tube. Thank you!

[@nastarannazari5062]

I love your channel!!! We have to pay for college and then come back to KZbin for understanding the concept totally.

[@vanshajchandra8031]

Such an underrated video ,you deserve more views

[@debigdogk9563]

I never thought I could understand this topic, but you made it so simple to understand. Thank you, thank you, and thank you. God bless you for teaching ❤❤❤❤❤

[@Mariamfa_]

Thank you so much for creating this video I truly appreciate it. It's so informative, organized and saved me tons of time to understand and review it.

[@physiopathopharmaco4190]

Glad it was helpful!

[@lalobojasper2412]

More denovo pathophysiology of PCOS! Excellent Elucidation! You’re spot on !

[@thewholehealthlab]

really love the short quiz with explanations at the end!

[@readybride6838]

Precise and concise explanation. Thank you

[@blacktongs]

Best video yet, goes really well with your estrogen and progesterone production video! subscribed! Thank you :)

[@abalanslife2723]

The chicken and egg comment was on point, I have been looking for it without finding any references for this process

[@syedafiya687]

Very helpful ! Keep up the good work🎉

[@italogabriele7721]

Excellent expanlation. Very graphic. Thank You !

[@adegokeadewumi5390]

Best explanation ever😭Thank youuuu

[@kashishganglani2237]

Phenomenal work......you have made easy to learn and time saving lesson. Waiting for more such videos.

[@makeeasy3891]

Highly recommended this video 👍👍 Thank you guys who made this..❤️❤️

[@sindhsaiyam]

Wow what an explanation plz tell us how we can get rid of PCOS

[@Dr.PraveenyaMahanthi]

Excellent excellent no Great textbooks have explained this way

[@ifrahakbar5462]

People like you are blessing to this world ❤️

[@nghiapham1644]

Best explanation yet!

[@ahmedbasim7368]

Sir you are amazing 👏

[@lukenelson6027]

Excellent explanation

[@fdejvbhtjc4927]

Great explanation👏 thank you very much

[@parinaverma8984]

thankyou for the great explanation! it cleared all my doubts😀😀

[@ghazalmohseni5935]

Great👍🏽

[@roo8ro847]

Amazing explanation ! Thank you 🤍

[@physiopathopharmaco4190]

Glad it was helpful!

[@euniceowusuansah8685]

Best video

[@divyavanipanneru9046]

Superb👏

[@Qamarali1]

Thanks for sharing Very informative

[@dingdong436.]

Superb explanation. Thank you very much!🤩

[@Pratikshashelke-m8f]

Soo good. And detail information .thanks

[@tuannguyenuc395]

Thank you so much for this explanation!

[@physiopathopharmaco4190]

You're very welcome!

[@eliseeidem9092]

Amazing video, thank you!

[@makyd6275]

thank you so much!! amazing ♥

[@yasersibai6595]

Very useful. Thanks alot

[@ranifaizagul8558]

Wow explanation

[@poolking2857]

Thank you so much

[@lisak6343]

excellent

[@dilafruzkhamidova_]

Great explanation 👏

[@dashimansu]

very nice explanation..THANK YOU !!!

[@JosyJosy-x6q]

very good explanation, thank you so much

[@dr.nitikasingh4564]

What an amazing explanation 😃

[@dailydoseofmedicinee]

Good explanation 👍

[@tanyayusuf5022]

Thanks alot ❤

[@MoustafaElattar1]

Great explanation, thank you 🙏🏻

[@MrAndyroni]

Excellent.. 👏 👏 👏

[@rechardwarlson7066]

Thank you , excellent illustrations

[@laurenhoffmann7978]

this is AMAZING

[@georgebacon4720]

Fantastic video - brilliant explanation! Thank you :)

[@mariamoghimi7713]

Thank you for this video! Brilliant explanation :)

[@obayrafi2632]

Very greatly explained, thank u

[@mohammedmatar2705]

Thank you so much doc ❤️❤️

[@olvembeb7024]

amazing

[@Ibhazeblessing]

I have PCOS and I remember how I felt when the doctor told me it would be hard for me to conceive I now have 4 children very successful pregnancies. God blessed me! with use of herbs 🌿

[@50naflanoorin41]

😍😍nice explanation

[@Ultrman97]

Great explanation thank you

[@ghostintheshell1431]

Awesome video, thank you🍀

[@dianajamous6644]

wonderful

[@dayfly1066]

thank you soooo much!

[@yasminkhattab3473]

Thank you This is very helpful

[@cleopaschisanga5355]

Best explanation man

[@Dear-Est-Her]

Thanks for the video, however I do have a question. 3:19 What is the basis for the production of the insulin by the pancreas and what makes it abnormal and different from a patient without PCOS?

[@safurabano8212]

Awesome

[@suhafares373]

Great explanations thanks

[@esraaabdel_shakoor6609]

V helpful ✨ 👌

[@nonyeonochie3250]

Greatttt🙌🏽🙌🏽

[@harworld4947]

you are amazing 👏🏻👏🏻

[@MichaelAlanAlien]

Is this a dangerous situation for my lady. Thank you

[@PsychicReadingUsaFacebookGroup]

Definitely wasn’t planned with pcos at least not so soon and ended up with twins. We’re both happy though

[@abhisheksuraj4992]

Thank you.. Great explanation

[@prasannabharathi2019]

Supperbb❤️ explanation 🙏

[@fathimamohamedali5267]

Both ovaries are bulky and shows multiple peripherally arranged follicles with echogenic stroma_ POLYCYSTIC OVARIES

[@DeponsiaYrn-go6yh]

When young I have had a lower back xray after a road accident where they checked if my spine was fine. Years later I have cysts and irregular periods. and I'm wondering if the xrays are the source. Especially since no one in my family has the irregular periods

[@MsPearl_]

Hello , Can you please explain, what does it mean on the diagram " ...past failed ovulation events" ??? What does this mean someone tell me please . Thank you

[@Cryptokite019]

Sir have a que ,if progesterone comes after ovulation and from carpos luteum ,then then how it will be the cause for gnrh high frequency ,as in pcos the follical doesn't ovulate. The how progesterone will come to cause this. Please tell🙏🙏 Is it occurs in next cycle?

[@nadiabehlouli2403]

Thank you

[@nadinethart]

Thank you for the video! I just had one question: what if you have diabetes type 1 and PCOS?

[@Cryptokite019]

If you understand then can you clear up my doubt

[@Cryptokite019]

have a que ,if progesterone comes after ovulation and from carpos luteum ,then then how it will be the cause for gnrh high frequency ,as in pcos the follical doesn't ovulate. The how progesterone will come to cause this. Please tell🙏🙏 Is it occurs in next cycle?

[@shujiafzal2187]

@@Cryptokite019 In the normal menstrual cycle, when the graffian (antral) follicle ovulates, the egg is sucked up into the fallopian tubes whilst the remainder of the follicle at the ovary becomes the corpus luteum. Normally, the corpus luteum produces progesterone which exerts negative feedback on the hypothalamus such that GnRH pulsatility is decreased to reduce LH/FSH levels and prevent further ovulation. However in PCOS, the follicle does not ovulate such that the corpus luteum is not produced - the follicle remains as an arrested pre-ovulatory follicle in the ovary thereby owing to the polyCYSTIC aspect of PCOS. As there is no corpus luteum, there is NO progesterone produced to negatively feedback on the hypothalamus - as a result GnRH pulsatility increases. As fast GnRH pulses favours LH production, there is a high LH:FSH ratio. The high LH leads to increased androgen production via theca cells which cause hirsutism and acne, alongside insulin resistance which also amplifies further androgen production as it has co-stimulatory effects with LH. On the other hand, low FSH prevents complete follicle maturation as there is no inter-cycle rise/fall such that there is no selection of a dominant follicle. This is why PCOS women present with irregular menstrual cycles and anovulation.

[@miruuish]

Hi and thank you for your compelling video about this condition! I have one question, please. If low progesterone (due to lack of corpus luteus genesis) is the cause of the increased frequency of GnRH secretion through the physiological negative feedback, doesn't that already imply ovulation not happening? I think I didn't get the primum movens of this vicious cycle correctly. Is it the hyperinsulinism? Thanks :D

[@daisyy2126]

Perhaps that’s why it’s thought to be a chicken and egg scenario as doctors aren’t sure what causes it. I’m not sure though I’m not a doctor

[@RFN871]

Great 💚

[@sephoraahsan577]

As read by the mandalorian

[@aliabduljaleel4295]

Thank you !!

[@xyzpeace7814]

❤️❤️❤️❤️

[@aquachik18]

thank youuuuuu

[@Medicalblocker]

Why The FSH don’t rise too?

[@ahmedaziz8725]

Gòod job

[@hindujag4948]

Master

[@emilybaker760]

Metformin really helps!!!

[@jay5281]

Yeah, do you have anything else to say about the drug other than that?

[@sirapobpotjanapimol5148]

God’s EXPLANATION

[@bliza9220]

hey yo, you are amazing

[@Imhosanna]

You sound exactly like Pedro pascal

[@maryanngelia9309]

👏👏

[@Cryptokite019]

Please tell

[@opaloakley]

I have a perfectly regular period every 29 days. Does that mean I ovulate?

[@luciramos8526]

Same here !?????

[@ryanlwan]

Highly likely , however , some have periods without ovulating , gynecologists can test for this though.