Absolutely fascinating. Imagine me, a plumber, knowing all this amazing stuff haha 😂 Love your videos Professor Dave!
@jwb9323 жыл бұрын
I feel llke our congressional representatives who believe in Jewish space lasers and shifting the orbit of the Earth need to start watching Professor Dave's videos.
@WanderTheNomad3 жыл бұрын
I think they would just get angry because they don't understand what's being taught, and then double down on their previous stances. Because that's their safe place where their brains don't have to worry about being exerted.
@santicruz40123 жыл бұрын
Its been a year since you inspired me to study biochemistry and Im loving every second of it. Thanks professor Dave
@toddc27073 жыл бұрын
As a 9th Grade Science teacher, I absolutely love this channel. There is so much that I steal for my classes. I feel we have all been cheated that he has had to dedicate so much of his time to debunk so much pseudoscience, instead of making educational content about real science because Dave is the best Science communicator on the web. I’m a big fan. Your hard work is much appreciated Professor Dave. Thank you.
@mhutflash55126 ай бұрын
With you. It's a wonderfull break down for me to see that I grasped my 3 years research in signaling cascades up to this point in following the Bilayer and RAS-RAF-MEK-ERK-MAPkkk/kk/k-pathway.
@joeisdude3 жыл бұрын
Hey Dave, sorry that this is off topic. I have 2 questions... why did you create this amazing channel? What was your goal? If there is one, have you completed that goal?
@ProfessorDaveExplains3 жыл бұрын
Well I was just looking for some passive income, so yes that was definitely achieved! And now I'm motivated to create a huge database of educational content, so that will be in progress for some time.
@joeisdude3 жыл бұрын
@@ProfessorDaveExplains that’s awesome! I can’t wait for the new videos!
@Blubb50003 жыл бұрын
Very educational video about complicated scientific topics: 1432 views Flat Earth debunk video: 241783 views A single 8 second video of a cat falling of a table: *54 million views*
@sciencenerd76393 жыл бұрын
His science tutorials do accumulate views over time though. Some of his older tutorials about chemistry, anatomy, astronomy, etc do have more than a million views. The important thing is it's a valuable free educational resource that people around the world can use whenever they need it.
@WanderTheNomad3 жыл бұрын
This^
@teresakaw12703 жыл бұрын
Why I don't understand this topic???😭😭😭😭 I'm not bright enough to get it?? 😭😭
@ProfessorDaveExplains3 жыл бұрын
Well you need to know some things about biochemistry and biology first. Check out my playlists on those topics!
@frankchen42293 жыл бұрын
Do computer science!
@Marytere83 жыл бұрын
‼️😱 WAOOOOO ‼️👏👏👏👏👏
@emmanuelweinman96733 жыл бұрын
the complexity of everything is just amazing. too bad I can’t remember everything...
Super cool, Professor Dave! You bring out the best informed nerdiness in all of us! Looking forward to the continuation of this series. Being a civil engineer, rather than a microbiologist, I've always wanted to understand the actual mechanisms of cell function. I can break down a rocket propulsion system, a squirrel-cage induction motor, or an internal combustion engine - each complicated in their own way - but I'm going to need your help to break down how a cell works. Should be a fun trip!
@sciencewolf77753 жыл бұрын
As someone who’s studying the immune system and microbiology, thank you
@cynthiad_3 жыл бұрын
I love love love this video 💯❤Thank you for sharing this 🙏❤
@palantir1353 жыл бұрын
Nice refreshing of what I studied a long time ago.
@josue25 Жыл бұрын
Great content. After dropping out of college years ago, I decided to reenter school January of this year. My first semester back involved studying diligently and wrapping everything with your videos. It's fair to say that I was the top student in my anatomy & physiology, chemistry, and Microbiology courses. You're good at simplifying all the technical stuff. You should get a 'teacher of the Year' award. 😊🎉🎉🎉🎉🎉🎉🎉
@windigo0003 жыл бұрын
interesting indeed 👍
@kaustavmitra42103 жыл бұрын
Sir it's really awesome, that you are finally making videos on biology....a teacher like you who makes chemistry a cake walk,is surely going to destroy biology.. looking forward sir... thank you very much
@venkatachengalvala42893 жыл бұрын
Well, chemistry and biochemistry affects (nearly dictates) biology.
@kaustavmitra42103 жыл бұрын
@@venkatachengalvala4289 absolutely sorry...i meant to say awesome...but my autocorrect made it awkward...
@backstreetfan28873 жыл бұрын
Signal transduction has always fascinated me. The graphics in this video are amazing. Keep up the good work, thank you for all you do.
@lynxica21333 жыл бұрын
day 1 of asking professor dave to make a music playlist where he teaches us to make music
@ProfessorDaveExplains3 жыл бұрын
One day I will do music theory as well as piano and drum instruction!
@lynxica21333 жыл бұрын
@@ProfessorDaveExplains ty!
@glennpearson93483 жыл бұрын
In the meantime, if you haven't already, go check out Professor Dave's other channel. There is some really cool music-related content from his earlier days.
@deathnote41713 жыл бұрын
@@ProfessorDaveExplains professor Will you Make a Series on Debunking All the scientific , philosophical and Mathematical Allegations and arguments against Evolution in Future? Also if you dubbed your Debunking videos in your other languages Channels you may find more subscribers and also make Debunking videos on hot topic which is famous among other languages speakers it will give you Audience in your other languages Channels
@MaxDiscere3 жыл бұрын
I study Bioinformatics. I don't even need to know this but when you explain it it instantly gets interesting😅
@Tntpker3 жыл бұрын
Depends on what topic youre studying. You need to understand this for structural biology
@mxy75823 жыл бұрын
Cool
@garimaa53113 жыл бұрын
❤️❤️❤️❤️
@Marytere83 жыл бұрын
Thank you very much for transforming the difficult into easy to understand, congratulations, a big hug👏👏👏👏
@James-Lee-Smith3 жыл бұрын
Professor Dave is a handsome man. I'm not flirting; I'm just a straight guy who is confident enough to admit when a man is handsome.
@mhutflash55126 ай бұрын
Q: What do you get if you penetrate the membrane in a way alterating charge and lipidstructure when receptors directly affected by that preconditions? Narf: Get your next booster and figure out how you messed up with PI3K (PtDins-cyclus), MAPk as part of the activation and all the nice crosstalks in this network?
@stephaniegreige6013 жыл бұрын
Hi Pr Dave! Do you have any recommendation on protein extraction procedure from liquid and solid phase of waste feeds (whey, alfa and poultry slaughterhouse)? thank you
@aftermath73 жыл бұрын
The opening is lit😂🔥
@Logan8003 жыл бұрын
bro I'm thumbing this video down this looks nasty don't show me this again it looks really disgusting and creepy
@lc17773 жыл бұрын
Professor Dave, in this world of increasing ignorance and conspiracy, there dosent seem the point for me to pursue science(and mathematics) anymore, because more and more people will just say it is all lies, then what's the point of studying mathematics and science when at some point people are going to lose complete trust on it? They reject mathematics as the descriptor of reality, reject the scientific method, which renders their position as unfalsible, do you think this ignorance will increase or decrease in the future?
@j.d.martin66783 жыл бұрын
Naw man, that's just the vocal minority you are seeing. Magical thinking is on the downswing in the later generations. The old guard is seeing their influence waning so they are lashing out more and more is all.
@ProfessorDaveExplains3 жыл бұрын
Don't focus on the cult of ignorance, focus on the potential of mankind, and your ability to contribute to progress. Leave the idiots to me.
@lc17773 жыл бұрын
@@ProfessorDaveExplains that's very encouraging and gives hope this period of ignorance will end and a new dawn will began , thanks for educating me as well, i have learnt a lot from you and your channel.
@northernskies863 жыл бұрын
The culprit mainly responsible for the cult of prideful ignorance is social media echo chambers of misinformation. If only social media companies would be more strict on misinformation, the problem of ignorance can be tamed because hoaxes and conspiracy theories spread like wildfire on social media if left untreated. Don't let the minority of idiots ruin your potential to do great things. There are plenty of very smart people on this planet and karma will weed out the few prideful idiots.
@VaughanMcCue3 жыл бұрын
@@ProfessorDaveExplains. Saint Dave is hereby appointed The Idiot Slayer. Accoutrements. White lab coat Confabulating god goggles to blur reality DEATHascope across your shoulders. :)
@wjrasmussen6663 жыл бұрын
That was a mouthful!
@JoakimKanon3 жыл бұрын
I feel like a dog listening to humans speaking.
@aj-uo3uh Жыл бұрын
Not so clear. First gtpase is discussed then g- proteins. Not clear if they are the same. I see that gtp is coverted to gdp but not who is doing that.
@WilliamSmith-gx8ed3 жыл бұрын
What does red star on cap mean? Bill
@jalapenoandbanana3 жыл бұрын
I have no knowledge of immune cells ☹️
@sciencenerd76393 жыл бұрын
You can check out the earlier installments of this series if you would like! Immune cells are pretty amazing!
@Avatarlifeplays6 ай бұрын
5:14
@AbdulHannanAbdulMatheen3 жыл бұрын
👏🙂
@RobertAugustine-w6e7 ай бұрын
thanks Dave, what a W
@gurudevice3 жыл бұрын
Great😊
@BlueLizardKing3 жыл бұрын
Dr. Professor Dave: I understand absolutely none of this, but I like listening to you explain it.
@CIS8613 жыл бұрын
Hello Prof, Please do you have a video on nano chemistry?
@andreigas3 жыл бұрын
this man looks like critikal if he finally got a haircut
@problemsolutionbysujan28033 жыл бұрын
How to graph pedal equation points please from nepal
@sciencenerd76393 жыл бұрын
This is great stuff
@TheInspiry2 жыл бұрын
Thanks Prof. Dave a lot ^^
@frankmccampbell33773 жыл бұрын
We Kick Butt Everyday, Yeah
@venkatachengalvala42893 жыл бұрын
Nice work! :)
@ashwina53173 жыл бұрын
Malayali like adikk
@xeneg12393 жыл бұрын
👍
@aj-uo3uh2 жыл бұрын
Very good!
@WanderTheNomad3 жыл бұрын
Ligand > Receptor > Conformational Change > activated Kinase Enzyme > Phosphorylation > Amino Acid > Changes in Protein Phosphatase Enzymes can reverse phosphorylation and toggle the changes in protein. (On-off switch)
@WanderTheNomad3 жыл бұрын
G protein coupled receptor > binds to ligand > summons G protein heterotrimer with GDP attached > GDP converts to GTP > G protein heterotrimer becomes activated > activates multiple pathways in cell(causing changes) GTPase converts GTP back into GDP, deactivating the G protein heterotrimer(on-off switch) Edit: Is the G protein heterotrimer the same as the large GTPases? 🤔
@WanderTheNomad3 жыл бұрын
T cell receptors without attached kinases > ligands attach to T cell receptors & coreceptors(friends) > receptors & coreceptors cluster within cell membrane > intracellular tails form docking sites for kinases Kinase Enzyme > Phosphorylation > Amino Acid > Changes in protein Do the docking sites perform the same role as the conformational change in the receptors with attached kinases? 🤔
@WanderTheNomad3 жыл бұрын
Small monomeric GTPases anchored to inner side of cell membrane, remains inactive when bound to GDP Ex: Ras/Rac/Rho 🤔 Are the small GTPases normally bound to GDP? Ligand > Receptor > adaptor proteins localize to cytoplasmic(intracellular?) tails > recruits G-N exchange factors(GEF) > swaps bound GDP to GTP > activates small GTPase > launches cell signaling cascade(activates multiple pathways in cells?)
@WanderTheNomad3 жыл бұрын
Cell response to ligands depends on 1) ligand concentration 2) receptor expression levels(density/concentration/prevalence/frequency?) 3) combination of activated receptors 4) order of receptor activation
@lmtrevino73 жыл бұрын
I can't believe this is new! I literally need this for my biotech lab course. Do you have more content on practice Master in Biology questions? Would you create one or maybe neuroscience
@ProfessorDaveExplains3 жыл бұрын
Check my biopsychology playlist!
@lmtrevino73 жыл бұрын
@@ProfessorDaveExplains thank you
@mhutflash55126 ай бұрын
What I can't believe: The same guy told you how great a 100 percentage N1-methlyated.pseudo-U-mod-RNA is and didn't even question the strange codon mods in the 3'UTR, 5'UTR and Poly-A and tells you: No worry if you pack it into a LNP-formulation penetrating your cell surface?! Stupid, sick, or payed?! Or just didn't grasp PtDins-cyclus?! Wanna talk about 8k+ alterated Genexpressions? See Ndeupen et al.?
@Bristol-MyersSquibb3 жыл бұрын
So you’ve literally seen what your teaching happen… doubt it… def not a professor