Psychedelics: Exploring the Brain | David Erritzøe | TEDxAarhus

In his talk, David introduces us to psychedelics and his research on how they might be a key to solve the problems with mental illness.
David Erritzoe is a medical doctor and clinical psychiatrist. In the years after finishing medical school at Copenhagen University in 2001, he trained under Professor Marc Laruelle at Columbia University in New York City, and later under Professor Gitte Moos Knudsen in the Center for Integrated Molecular Brain Imaging (CIMBI) in Copenhagen. The subject was molecular and functional brain imaging.
In 2009 he completed his PhD on serotonergic neurotransmission and subsequently moved to Imperial College London to conduct post-doc addiction research under the mentorship of Professors Anne Lingford-Hughes and David Nutt. At Imperial, David has been involved in psychopharmacological and brain imaging research, mainly investigating dopaminergic and opioid neurotransmission in addiction. In addition to that, he is part of a research programme together with Professor Nutt and Dr Carhart-Harris conducting research in neurobiology and the treatment potential of MDMA and classic psychedelics.
This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at www.ted.com/tedx

[@anthonydunn729]

Remember, if you're gonna try psychedelics, make sure you're not gonna be around strangers or anything else you might be uncomfortable with when really high. Do your research and have a kickass, potentially life changing time.

[@scottkennethjones]

Anthony Dunn sweet profile pic

[@catgirljourney4593]

go be in nature and don’t look in mirrors!

[@keshy5756]

@@catgirljourney4593 idk why tho, looked into them on shrooms, on acid too, literally nothing more interesting than looking at pics or outside.

[@Zer0TheProdigy]

I've been getting interested in Psychadelics after dropping LSD about a month ago. I'm glad this along with Marijuana has been a hot topic among people around the world. Everyone is taking a step back like "Hold on. The government has been lying about weed for several decades now, now what other beneficial Schedule 1 drugs have they been lying about"

[@solidaritytime3650]

Hey! Have you tripped in the year it's been since you commented this?

[@Julzchomovitch00]

@@solidaritytime3650 We'll never know

[@askalice7222]

@@solidaritytime3650 and oh no! A clipboard!

[@mayapatuel1459]

Psychedelics imo are the very best healers n teachers life offers!

[@guilhermepimentel2744]

Are we gonna ignore the fact that his boots are cool

[@Fedor526]

It is was very important to him that we notice his boots haha. Great talk though

[@vickielawson3114]

Are we gonna ignore the fact that his pant legs are messed up?

[@mulecemrun3639]

He is absolutely right that we should monitor psychedelics administration in clients in order to get desired outcomes, if otherwise it would be similar to destruction and split of personality! so they should be administered by expert and not by individuals! A very serious Ted Talk!

[@wakkowarner8810]

Muhammad Imran Ghallow if they didn’t follow safety procedures they’d be members of the CIA and not doctors

[@askalice7222]

oh for the love of all that's good and holy!! Willl you science type people quit rambling on about the rest of us being blithering, cowering idiots!!!

[@usdjxavi]

Can i sign up for this experiment?

[@vickielawson3114]

That cathedral at 5:57 is absolutely stunningly beautiful.

[@looseunit9180]

Wonderful

[@alexullrich5694]

Wow Mark Ruffalo really got into this role

[@kiracarinamckeague3651]

OMG I thought that too! LOL

[@tiluriso]

9:15 - OK, but one does get a child-like-curiosity-feeling while on LSD - I did, many times.

[@gama6749]

Earnin app easily most hated ads on KZbin

[@zbanch123]

Theun Mares books may help in such situations also. They contain technics to cope with painful memories.

[@witwisniewski2280]

Why are experiments now and in the past done in what looks like a hospital setting? It seems to me that interaction of the subject with the environment may be a huge factor in what the treatment will realize, and humans can interact with enormously complex environments, so why the austerity?

[@TheSpoonwood]

Who did the sound on this?

[@jopmens6960]

I think part of the therapeutic effects are from downregulation of 5-HT2A. Lower activity of this receptor is associated with lowered stress, better sleep and many other things. I agree though that the experience itself can also be transformative, priming, and one of the things which apparently can be helpful is the breaking of cramped and rusty thought patterns. However this potential can probably be utilized for very positive but also negative change depending on the quality of the experience, which much like meditation is a way of brainwashing without necessarily the negative connotation. An LSD experience actually bears a lot of similarity to a week-long meditation retreat in my experience. I think this should serve as a hint to do research on similar therapeutic effects meditation has found to have with psychedelics to see which ones can be confirmed.

[@mr.mojorisin2547]

Jop Mens I believe you’re right, psychedelics seem to break unhealthy thought patterns. So does meditation, but meditation requires a lot of self control which some people with these problems do not have. I think a profound psychedelic experience paired with meditation is the answer.

[@wakkowarner8810]

Jop Mens meditation takes a long time, some people need the quick action of psychedelics to get the benefits so that they can then be taught how to meditate to maintain the benefits.

[@infestedfetus]

imagine if ADAM & EVE tooks Magic Mushroom instead of apple...

[@shaic.8406]

Kim Jong Un some religions believe it was a magic mushroom not an apple and that’s why their mind expanding so much.

[@avantelevine6313]

What if the mushroom was the apple...? That's why we try to find our way back.

[@koistya]

Apple was never mentioned in Adam & Eve story.

[@sallymasterson-matychowiak6262]

that would have been awesome!

[@vickielawson3114]

@@protoxus Apes are sentient (able to think and feel things). You mean sapient (ability to know things and reason with that knowledge).

[@witwisniewski2280]

We hear "expand your consciousness", but we lack a meaningful explanation of what that means. Expand exactly how? Expand into what? We need to be more precise in describing and measuring what happens in these highs. It seems that we don't even have language to describe the experiences and impacts.

[@aaronawoodard]

Take some more psychodelics until you realize spave exploration is as important as the exploration of our own conciousness. They are actually rather similar, the way the universe looks and the neural mapping of a brain that is...

[@vanfl9911]

What if magic mushrooms and other psychedelics are illegal bc our ancestors succeeded so much with these "drugs" and were getting ahead of their time bc of these items so the government wanted to make all the "big changes" and are selfish about growing as a country and or species?

[@randomrangoon5476]

It was closed down because no money is made from a cure. Too many closed minded people that carry a lifetime of stigma as well I think it's that simple.

[@williamdburton-xl9hk]

Unrestrained Cognition!

[@prasenwaikar5761]

this video is osum

[@MrSchweppes]

“Psychedelics are illegal not because a loving government is concerned that you may jump out of a third story window. Psychedelics are illegal because they dissolve opinion structures and culturally laid down models of behaviour and information processing. They open you up to the possibility that everything you know is wrong.” ― Terence McKenna

[@hezuikn]

historic reasons?

[@sanjuansteve]

I think I may have a near total cross hallucinogenic tolerance. I've only had (other than weed) LSD twice and mushrooms twice, but I predicted the 1st time with LSD would have little affect and so took 3 tabs of what were said to be double dose (600 mu) tabs and they had quite little affect on me. My next time with LSD and 2 times with mushrooms were all also supposedly similarly heavy doses, all from totally different sources and all with nearly no affects. I look forward to really diving in to this mushroom season coming next month and my first chance with ayahuasca, but I have zero faith that they have the capacity at virtually any dose to confuse my brain. lol Someone should add me to some study, if remotely, because I think it's a rare thing and so it would be interesting data.

[@ynysmones3816]

thats pretty strange. does weed effect you?

[@phillipadams6735]

I bet you won't have any questions after Ayahuasca. Be prepared. The more you look for positive experience, the more you will have.

[@toddstracener9897]

Sometimes you need a trigger, some good chill music or some music videos with some nice visuals can do the trick.

[@sanjuansteve]

Y2K, Weed used to affect me like normal, then I built-up my weed tolerance over a few years to the point where one day, I literally could not get "high" from weed at any dose either. I also lost the ability to get the munchies that day and felt like / predicted that I lost the ability to feel anxiety, fear, anger or envy, which have proven true so far and that was 5 years ago. I moved to Washington state in 2015 and lived in a house that made dabs that were better than the 87%> THC medical dispensary dabs. I had only smoked regular street weed before but predicted the dabs would make no difference, and it proved true also.

[@wadada2522]

What are you actually looking for?

[@montesa9136]

So, if you suffer from severe depression you have to keep taking Psychedelics every few months?

[@smackpointgsps1476]

For many it's a one and done fix. For some, it's helpful to "top up" occasionally, be that at 3,6 or 12 month intervals. It all comes down to the individual and their own issues. For myself, I top up every so often as I have been using it to work through complex mental and physical issues. But each time the interval gets longer and longer. And it will not be a long term necessity, like the other meds I have been on for almost 30 years.

[@montesa9136]

@@smackpointgsps1476 @Smackpoint GSPs - Thanks for the information. Any chance we could talk?

[@montesa9136]

@@smackpointgsps1476 @Smackpoint GSPs - you mean you can just take one dose & it can cure your depression permanently? How big a dose would that be?

[@smackpointgsps1476]

@@montesa9136 absolutely

[@smackpointgsps1476]

@@montesa9136 yes, for many people, one dose is all it takes. I have had great success using 2gms per session, currently every 3 months. For me, I'm working on CPTSD from child abuse, depression, anxiety, neuropathy and dissociative identify disorder. I'm using it as I pull the mental threads on my childhood, to try to change the way I react to things. So for me it is an ongoing process. But after the very first dose, that internal, negative voice was silenced and I no longer thought about suicide, which was a serious daily struggle for me. It has, and is changing my life.

[@infestedfetus]

how i wish Magic Mushroom is planted at Garden of Eden long time ago. not an apple.

[@greatghost469]

you are awesome sir

[@smackpointgsps1476]

Many believe that it was.

[@gamercatsz5441]

Bro, the apple was laced with water, Pure simple water, Mixed with lsd.

[@briangard951]

The fruit of the Tree of Knowledge either Amanita muscaria of a psilocybin mushroom - prolly - though Adam and Eve never existed.

[@elokubano]

Harsh comment loading: 'How to turn an endlessly fascinating topic into a coma inducing talk'

[@askalice7222]

Well done! I love it! Are you from the UK by chance? ( The sense of humour)

[@sedunk7511]

Love this stuff but just can’t get down with this guy.

[@humanyoda]

If David weren't a psychiatrist focused on drugs, he'd know that there are transformational psychological processes that allow people to quickly let go of their depressions, phobias, anxieties, etc. He'd also be less confused about how psychedelics do what they do.

[@patrickfoster4586]

humanyoda "let go of their depression quickly". Are you kidding? If psychiatry offered a quick cure for depression how is it their are millions of Americans suffering from it currently? I can tell you that SSRI's and blabbering on a couch do NOTHING for actual major depression. In reality they have nothing useful to offer the patient who suffers from depression, not to mention "treatment resistant" depression.

[@groob33]

Please enlighten us.... I would love to hear more about these transformational psychological processes. Seriously.

[@laurenbriscoe6547]

Please know psychedelics can trigger psychosis can mean terrrifying mental images, flashbacks, being unable to speak or eat or drink, deranged behavior, violence, inability to work and function, loss of intelligence, creative skills, cognitive skills, extreme depression, loss of identity, inability to parent, suicide, delusions, paranoia, auditory and visual hallucinations, loss of job, hospitalization, and possibly homelessness. The depression afterwards can be severe and take years to recover from. Many people have suffered. I’m not exaggerating.

[@gamercatsz5441]

Yes you are exaggerating, and also spreading false information!

[@jameshadfield5624]

It sure sounds like more than an exaggeration. fantasy maybe, reefer madness -like

[@laurenbriscoe6547]

@@gamercatsz5441 It can't be false when this is literally happening to people. You don't have to do much research or look to far to find these cases. These substances affect the brain and some people have psychotic breaks.

[@laurenbriscoe6547]

@@jameshadfield5624 Not at all an exaggeration. I've talked to people to have had this happen and found more cases of this upon researching. Research things fully before stating what something "sounds like."

[@jameshadfield5624]

@@laurenbriscoe6547 well you can keep talking to your zombie acquaintances, I'm talking about personal experiences. nothing ventured, nothing gained! it's snooty sheeple like you that keep society stuck.a closed mind is a terrible thing to have, even worse when it spores nonsense and heresay. Peace

[@zzid9110]

This guy shouldn't talk in front of an audience.

[@jaanaunapuu5910]

But... why?

[@humanyoda]

Because he can barely utter words.

[@masonm2684]

He had some rough spots, but it added personality and made it more enjoyable to listen to.

[@mr.mojorisin2547]

In the description it says he studied at the Copenhagen university, so I would believe English is not his first language. Give him a break

[@Peteru69]

Most Danes speak pretty fluent English, at least the younger generations. This guy just has a really thick accent, if you can't understand what he's saying that's on you. Perhaps you should work on yourself instead of projecting.

[@majortom642]

As interesting as this guy diction is painful. Had to stop...