Thank you Dr Grob for this fascinating, informative, and comprehensive overview. Your clinical, scientific, and ethnographic experience is well grounded in data and matched with your wisdom in importance to attending to appropriate care. I also share your concern and honor your opinion that the therapeutic use of these potentially healing substances should be safely guarded from profit enterprises. As our understanding of neuropharmacology expands I applaud your tenacity in academically pursuing your research despite cultural and political obstacles. Your work has been a bridge to the future and if done wisely as you suggest can be transformative for many.