R2. Pre-Steady State and Steady-State Kinetic Methods Applied to Translation

[@peybak]

Wow, this is an eye opening lecture tbh. I've studied enzyme kinetics a few times over my life and have never thought about the questions she is asking. She is a great teacher.

[@llewellynhamiltoniiim.d.1057]

Interesting.

[@ruairidhmcmillan2484]

Hi MIT. Is this an UG or PG level class? Thanks.

[@mitocw]

It's for both. See ocw.mit.edu/5-08JS16 for details. Best wishes on your studies!

[@matthewzhang2629]

Excuse me. Is anyone know what is the name of the essay that student were required to read?

[@mitocw]

The required reading is: Woorhees, R. M., and V. Ramakrishnan. "Structural Basis of the Translational Elongation Cycle." Annual Review of Biochemistry 82 (2013): 203-36. See the Readings section of the course on MIT OpenCourseWare for more details at: ocw.mit.edu/5-08JS16. Best wishes on your studies!

[@matthewzhang2629]

MIT OpenCourseWare Omg that is a Hard essay and have huge amount of details on each section. I am reading it and I already spent more than 4 hours. Thank you for telling me.

[@lucadanieli1995]

@@matthewzhang2629I'm quite confident that they are actually discussing the "T. Pape , W. Wintermeyer, M. Rodnina; Induced fit in initial selection and proofreading of aminoacyl‐tRNA on the ribosome; EMBO J (1999)18:3800-3807" paper

[@Batman-wf1co]

@@mitocw ..it's not a free article... how can we obtain one ? Thank u

[@KS-wt6yg]

@@Batman-wf1co Do u know about Sci hub?

[@prathameshdatar3006]

JoAnne Stubbe teaching enzyme kinetics? The only way you get better than this is if Mo Cleland himself returned from the dead!