Research update on vitamin B3 & glaucoma | Live Q&A with Dr Flora Hui | Glaucoma Australia

In this Live Q&A event, clinical scientist Dr Flora Hui Dr Hui provides a research update on vitamin B3 and glaucoma.
Please note to Glaucoma Australia’s knowledge, the Vitamin B3 trial mentioned in the video is no longer taking new participants as they have moved to the next stage. However, if you wish to find out more about the vitamin B3 trial or participating in any future clinical research related to eyes, please contact the Centre of Eye Research Australia at www.cera.org.au
#GlaucomaAustralia #SavingSight

[@a12bbad1]

The best and easy to understand explanation of Nicotinamide B3 i have seen, even when to take it and the dosage roughly.THANK YOU from the UK You should be proud of yourself

[@robp2282]

Important info: I had been taking nicotinamide since February 2022. When the results of this trial were published, I upped the dosage to 3g from 500mg, taking 3 am/3 pm although the times differed. whilst i noticed significant improvement in my vision it caused a big problem..... Continuing to take them, after 14-16 days I noticed I was struggling to pee. Then, I couldn’t pee at all- went to hospital and had to have a catheter fitted!!!! The doctors did not know what caused it, blood test was fine and no sign of a urine infection. They also couldn’t find any evidence it was related to nicotinamide!!!! So 2 months later, i started taking nicotinamide again. however i was more conscious on the timing, taking 2 am 2m lunchtime and 2 in the evening. Again, after 14-17 days, i struggled to pass urine without going into full retention- this continued for a full month. all tests have came back fine. i can only add that a 3g intake of nicotinamide caused a psychological problem where i felt the URGENT need to pass urine even though my bladder was virtually empty. I ended up causing trauma to my bladder where i have to pass urine several times a night- but at least im not straining to go now. my advice is don’t copy the trial until more information is released! I hope cera and dr hui can use this information and be alert for patients in their care! Bottom line- leave it to the experts!

[@paulvictor7814]

I have watched again ... very informative and very helpful. Thank you so much for sharing!

[@abubakarsharif6332]

Thank Dr Flora for these tips. I am now sufficiently informed on some of the challenges of the disease.

[@pamwren6866]

Thank you so much for the interesting and clear explanation! Great presentation! Natural and authentic!

[@tony-id1xp]

thanks very much, very informative.nothing more important than trying to help someone with vision!

[@wadap0]

Thank you!! You are doing God's work!

[@suewhite9477]

Thank you so much Dr. Flora. A fantastic presentation which I enjoyed very much and gained a lot of helpful information. The questions were really good and you answered them in a way which was very clear and easy to understand. I am very grateful to you for sharing your extensive knowledge and for conducting this Vitamin B3 study, which could help so many. Thank you.

[@Tinesj63]

Thank you for sharing this study!

[@kellydon2294]

Amazingly informative video Dr. Hui. One of the most succinct while still being brief health videos I have ever viewed! Thank you very much.

[@Simone-lb8zr]

Very informative video for glaucoma patients, funny fact I started being curious about boosting NAD+ a month ago (NR) after reading about benefits on nerve cells, and now I find this video. Dr Flora top speaker, perfect presentation. Please keep us updated.

[@paintedportraits3037]

Very good chat and answers well done

[@marissanavera4528]

Hello doctor just now I encounter and watch your video.. thank you for this information. I am suffering from glaucoma for almost one and a half year now

[@veenakrishna2198]

Thank you for the information

[@chimambahaotu167]

Dr Flora, I love your update it is a sound concept. Keep up the good work! I love you❤❤❤❤ Chima Mbahaotu of Nigeria

[@advsudipto]

I am taking vitamin b3 ( Nicotinamide ) after watching this video. I am 43 and lost most of my vision in both eyes due to glaucoma . I am taking the b3 almost a month . Please making another video for us regarding latest update and progress about the research. Thanks in advance Dr Flora Hui .

[@blackwulf8793]

How many mg are you taking?

[@ochudonobodo]

Has your vision stabilised or improved ? I also have glaucoma and need to know. Thanks 😊

[@georgeee5447]

Thank you so much Dr Flora Hui for your very educational, informative and inspiring session on this new glaucoma treatment discovery. May God bless you and your fellow researchers in this new discovery which could save the lives of millions of glaucoma patients. 🙏🙏🙏👏👏👏

[@DIABETESHEALTHS]

Thanks

[@patman888]

Hi Dr Flora Hui, does your dosage of nicotinamide have an adverse effect on patients with chronic kidney disease, eGFR around 55?

[@user-zp7bi4hk5f]

Thank you. Very informative. Must look for the supplement, nicotinamide, locally.

[@MsMyra22]

Thank you. Once I start with Niacinamide will should I continue for the rest of my life? I have Glaucoma. I live in Canada and am South Asian.How can I participate in your study

[@gilbertabdo8813]

can someone please recommend what brand you recommend- i went on iherb and most brands are expensive and have low mg not even close to 500mg - thank you

[@asimmoon53]

Very informative plus can I take nicotinamide with mild Uric acid age 36 male OHT patient

[@dr.amitabhamukherjee3601]

What is the dose being prescribed in the ongoing trial?

[@aperson1181]

If you cannot consume nicotinamide, what other B3 form do you suggest?

[@zdreamin]

is non flush ok? IS IV infusion NAD better?

[@maggiec8756]

I amvery interested to learn more. I am currently working with doctors to have an iridotomy so my eyes can drain better.

[@GlaucomaAustralia]

Hi @maggiec8756,if you would like any more information about the study, you can contact the Centre for Eye Research directly on Phone: [phone] or Email: [e-mail] Thank you, SA

[@carmelitasabellano5993]

Thank you very much for all the information. If you have the time to review this video, notice if your pushing up your oversize eye glasses almost every 5 minutes in not destructive 😮. So that's loose as well.

[@jocs8824]

what about exfoliative glaucoma? high homocysteine is found in eye regions and high dose b3 increases blood homocysteine. Has the study included those with this form of glaucoma? Maybe the low B3 in blood of glaucoma patients is a reflection of low B6 as it is needed for the conversion to b3 of tryptophan. B6 has homocysteine lowering property and used with b3 is safer maybe? is the study including other Bs with B3?

[@GlaucomaAustralia]

Hi @jocs8824, if you would like any more information about the study, you can contact the Centre for Eye Research directly on Phone: [phone] or Email: [e-mail] Thank you, SA

[@rredding]

Hi, this may be interesting to you.. Before a beginning glaucoma was detected, I did blood and DNA tests. As I am over 60, I have a yearly blood check, quite broad. My homocysteine is on the upper allowed limit and in my DNA there's a faulty MTTR gene (connected to the MTFHR). This results in poor methylation. In the past I learned that applied kinesiology can be a very fast, holistic way to find and treat issues in body and mind and in my country there's a very good, wise woman where I go to. She found that I have a methylation problem and prescribed me vitamin B2 (riboflavin). I looked it up in medical literature and indeed, B2 may help methylation. She tested me yesterday and told me also here a methylation issue is at play and I need to take 2 pills l-cysteine (bonusan) at least 30 minutes before a meal at for the next two months. This dose may not be combined with other supplements at the same time. I looked is up in medical literature, and indeed, homocysteine and l-cysteine are mentioned in relation to glaucoma. She also gave me some mental advice. Besides the l-cysteine, I already took NAC after getting out of bed and I should continue that.

[@jocs8824]

@@rredding Thank you. I think my case of POAG is low estrogen causation. It gets tricky because methylation removes estrogen.

[@rosem5060]

@@rreddingI have the pseudo exfoliation type of glaucoma. Have severe loss of sight in one eye. I am very interested in learning more about your treatment regime and the health practitioner you are seeing.

[@rredding]

@@rosem5060 hello, I am very sorry for you, this must have been a shocking experience! I live in the Netherlands and that is where she lives and works also. I know her for some 40 years. Touch for Health (TFH) or applied kinesiology is an alternative testing and healing method and I expect that she is one of the best TFH practitioners these days. I assume that you are not familiar with the TFH method and I will give you an example how I helped me. I have been high in triglycerides and low in HDL for tens of years. I can test my own lipid panel at home (Acon, Mission cholesterol testing 3:1) and I do this occasionally. I only realized recently that I should tell her about my values and when I did, she tested me and prescribed some supplements (chromium, vitamin E complex, beta 1,3 1,6 glucane, vit B2). Within a week after starting using these, my values improved greatly. I trust her capabilities and always follow her advice. Now my glaucoma is in the very early stage where I experience some very minimal blurring in the periphery of my left eye. Eye pressure is in the 19-20 range. During a test in the University hospital a beginning glaucoma was diagnosed. I did not get any advice and was told to return after 1 year. I do not like this approach and want to do what I can to improve my situation. My TFH therapist tested me and prescribed me with NAC and l-cysteine. In the past I lived very unhealthy. I already changed my diet a few years ago at 60 y/o to low carb, very low sugar, no vegetable oils, no margarine (I use real butter, virgin olive oil), no packaged food products, high omega 3 (fatty fish, fish oil capsules with EPA, DHA), no bread, no fried products and no artificial sweeteners, no sweet fruits, but a lot of black berries, blue berries, rasp berries, straw berries and lemons. Supplements: vitamins C, D3, K2, minerals Zinc/Copper, Iodine, Selenium, Boron. I do not know where you live or what to advise you. Probably you should contact a Touch for Health organization in your country (touchforhealth.us/) if you are interested. I hope you'll find good support! 🙏🏻💚

[@injungchang]

Could you provide brand name of the nicotinamide supplements used for the trial? I see several products such as True Nigen, Thorn Research, etc. But, not sure which one to get.

[@lightliz7834]

This gives us hope but 3g each day seems a very high dose - is this safe for long term use? Plus my BMI is only 19 and I weigh just 57 kg so would I need less Niacinamide?

[@GlaucomaAustralia]

Hi @lightliz7834, Participants in the study consume a higher dose (3grams) of vitamin B3 under strict clinical supervision. We would strongly recommend for you to stay with the recommended dose as instructed on the bottle/packaging for the product. To start a higher dose, you would need the okay to do so by a qualified doctor. This can be your GP or your eye specialist. Consuming a high dose of vitamins and supplement can have unwanted side effects. If in doubt, we would advise for you to consult your GP or pharmacist to discuss your suitability to vitamin B3. Thanks, GA Orthoptist.

[@lightliz7834]

@@GlaucomaAustralia Thank you - that is very good advice. I will discuss this issue with my doctors.

[@teddytca861]

is that NMN

[@ronihana9164]

Thank you very much Dr Flora Hui. in your study 3000mg per day only for 12 weeks and then you have to stop?

[@GlaucomaAustralia]

Hi @ronihana9164, if you would like any more information about the study, you can contact the Centre for Eye Research directly on Phone: [phone] or Email: [e-mail] Thank you, SA

[@risenshine2783]

Listen to it again! She tells you

[@hareshramnani]

Dear Professor thank you for your most informative video. My question was whether there is any evidence to combine Nicotinamide 3gr with Calcium Pyruvate 1.5gr for greater efficacy ?

[@GlaucomaAustralia]

Hi @hareshramnani, please contact research institutes such as Centre for Eye Research Australia to check on any past or upcoming studies in your area of interest. You can contact the Centre for Eye Research directly on Phone: [phone] or Email: [e-mail] Thank you, SA

[@mballer]

8:40 what dose was that?

[@olilumgbalu5653]

Why not take NAD directly instead of nicotinamide?

[@GlaucomaAustralia]

Hi @olilumgbalu5653, we recommend contacting the researchers at Centre for Eye Research directly as they are best placed to answer your questions. Please Phone: [phone] or Email: [e-mail] Thank you, SA

[@MixtrisUFOimages]

NAD molecule is too large and difficult to absorb by the body This is why precursors are used

[@richardbannerman4204]

Can someone with liver or kidney disease take Vitamin B3?

[@GlaucomaAustralia]

Hi @richardbannerman4204, We advise you to please discuss this question with your GP. They will be able to better advise you of your suitability to Vitamin B3. Thank you, GA Orthoptist.

[@peggyharriage2127]

Is this vitamin every where

[@mnayak9348]

Which food rich in NAD

[@GlaucomaAustralia]

Hi @mnayak9348, we recommend contacting the researchers at Centre for Eye Research directly as they are best placed to answer your questions. Please Phone: [phone] or Email: [e-mail] Thank you, SA

[@MixtrisUFOimages]

Any food containing vitamin b3

[@stevenorton1881]

Can you use this for pets too?

[@GlaucomaAustralia]

Hi @stevenorton1881, we do not have any information on Vitamin B3 and pets. It would be discouraged to give the vitamins to your pet without a discussion with the vet. - Thanks, SA

[@lightliz7834]

You could certainly increase your pets vitamin B3 rich food, especially if it is a dog or cat - give it fresh chicken and fish when you can afford it!

[@susannelarsen8089]

Give Cbd oil to your 🐕

[@nelsonpangilinan1116]

there are to many naiacin available but not the nicotinamide

[@roxyiconoclast]

It’s usually called niacinamide in supplement form.

[@nelsonpangilinan1116]

@@roxyiconoclast oh thanks a lot~~

[@petervafeades4095]

they all get converted to nicotinamide in the gut, no worries

[@lightliz7834]

1.5 grams each day for 6 weeks and then 3 grams per day.

[@GlaucomaAustralia]

Hi @lightliz7834, Participants in the study consume a higher dose (3grams) of vitamin B3 under strict clinical supervision, we would strongly recommend for you to stay with the recommended dose as instructed on the bottle/packaging for the product. To start a higher dose, you would need the okay to do so by a qualified doctor. This can be your GP or your eye specialist. Consuming a high dose of vitamins and supplement can have unwanted side effects. Thanks, GA Orthoptist

[@lightliz7834]

@@GlaucomaAustralia Thank you very much for your reply. I appreciate your advice and when I start taking Niacinamide I will take the recommended dose of 500mg per day. I will also discuss this with my eye doctor and my GP.

[@susannelarsen8089]

I take 3000 mg a day . My number is now 21 . It was 37.

[@patman888]

@@susannelarsen8089 What number is this? Eye pressure?

[@susannelarsen8089]

@@patman888 Yeas

[@mballer]

Woke young lady.

[@patman888]

Does this dosage of Nicotinamide lower IOP as suggested by@susannelarsen8089 below?

[@GlaucomaAustralia]

Hi @patman888, if you would like any more information about the study, you can contact the Centre for Eye Research directly on Phone: [phone] or Email: [e-mail] Thank you, SA

[@susannelarsen8089]

Yeas , remember with food