Rheumatoid Factor (RF) - Rheumatoid Arthritis (RA) - Joint disease- Rheumatology series

😍🖼Animated Mnemonics (Picmonic): www.picmonic.com/viphookup/me...
- With Picmonic, get your life back by studying less and remembering more. Medical and Nursing students say that Picmonic is the most comprehensive and effective way to bridge learning and test prep...
Disclaimer: I use affiliate links....
►👨‍🏫💊Antibiotics Lectures: www.medicosisperfectionalis.c... ... Check out my brand new "Electrolytes" course at www.medicosisperfectionalis.c... and use the PROMO code: ELECTROLYTES50 to get a 50% discount. Rheumatoid factor (RF) is an IgM autoantibody against the Fc portion of IgG. "an antibody against an antibody".
Rheumatoid factor (RF) is present in 80% of patients with rheumatoid arthritis (RA), which makes this test 80% sensitive.
Rheumatoid factor (RF) is not specific, because it can be seropositive in many diseases including rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), sjögren syndrome, interstitial pulmonary fibrosis, hepatitis B infection, essential mixed cryoglobulinemia, infective endocarditis (subacute bacterial endocarditis or SABE), tuberculosis, infectious mononucleosis (mono) and hematological malignancies...This, by definition, is non-specific.
Anti-neutrophilic cytoplasmic antibodies (ANCA) are IgG autoantibodies against the cytoplasm of the neutrophils and monocytes.
This is different from antinuclear antibodies (ANA) which are antibodies against the nucleus.
Anti-neutrophilic cytoplasmic antibodies (ANCA) have several patterns; the most important two being the cytoplasmic ANCA (c-ANCA) and the perinuclear ANCA (p-ANCA).
Anti-neutrophilic cytoplasmic antibodies (ANCA) are associated with vasculitis, such as granulomatosis with polyangiitis (Wegener granulomatosis), microscopic polyangiitis, eosinophilic granulomatosis with polyangiitis (Churg-Strauss), rapidly-progressive glomerulonephritis (RPGN), anti-glomerular basement membrane antibodies (ant-GBM or Goodpasture's syndrome), as well as inflammatory bowel disease-associated. vasculitis.
Get my 50 hematology cases at / medicosis
For mnemonics, try this www.picmonic.com/referrals/JK...
Sign up for Dropbox here: db.tt/IIlB8ejxWe
Books that I recommend: www.amazon.com/shop/medicosis...
To sum up, rheumatoid factor (RF) is an ​IgM antibody against IgG, associated with rheumatoid arthritis, SLE, and others. If you like my videos, please consider leaving a tip at www.paypal.me/perfectionalis/
► Visit my website: www.medicosisperfectionalis.com/ My Favorite Productivity App: airtable.com/invite/r/2zH40fus/ 📱Save on your mobile phone bill: fbuy.me/q6bMj 🏦 Qbank (TrueLearn): truelearn.referralrock.com/l/...

[@MedicosisPerfectionalis]

Get my 50 hematology 💉 cases at www.patreon.com/medicosis/

[@minedfield]

My friend, you're creating a real video-encyclopedia of medicine here. Brilliant work, keep going! 👏👏

[@MedicosisPerfectionalis]

Thanks, man 😊

[@mariacojocaru4080]

I left education at 16 and now I'm studying microbiology at university. I never heard of any of these things, but I need to know them so I can write about how parasites can suppress autoimmune diseases. I understood everything, you explain it all perfectly.

[@MedicosisPerfectionalis]

Wow! Thank you 🙏

[@Rebecca-zn8cz]

You are a perfect mixture of dry humor and essential information! I really enjoyed that little lecture❤️

[@MedicosisPerfectionalis]

Thanks, dear :) I am honored! Can you please help me by sharing?

[@rosh6369]

"oh my god I'm so deep" I lol'd in the library, thanks for that :P

[@MedicosisPerfectionalis]

My great students are known for laughing 😂 in libraries and during exams 😄

[@whiteguyplays6229]

5:20 "how I memorized everything in medical school" thats so trueeeee man!! 😂

[@MedicosisPerfectionalis]

Haha 😂

[@meriemdjouini8545]

Thank you very much , your video is more valuable than those expensive books and some specialty providers .

[@MedicosisPerfectionalis]

Thanks a lot, dear :) That’s the best comment I’ve had in a while 😊

[@donpiedro5085]

Increidable charisma)) Continue doing what you do, man, your videos are awesome and they're a great help. Subscribed right away)

[@Marvindorfler1]

Is it possible to have RA and not display signs of swelling in the early stages. I have been really stiff for the past 4 months or so and wrote it off. Until I began getting shooting pains in my fingers, bad fatigue, then pains in my toes and a sore heel. Went for a blood test and it came back with high rheumatoid factor. However I think I have caught onto this in its early stages and I dont think much damage showed up on the ultrasound and I dont seem to suffer swelling yet. Could this still possibly be RA without the obvious swelling ???? I got the impression the dr wasnt convinced, but I feel I have just identified it really early and there may not be much joint damage on display yet. Can you offer an opinion?

[@lostSempaiWissame]

Everything I wanted to understand for years now in one play list ❤️

[@MedicosisPerfectionalis]

Thank you 😊

[@LottoScratchin]

Can you go from RF Positive to RF Negative? Can meds like Enbrel change the RF from positive to negative after years of being injected?

[@caitlynkocher9572]

Perfect! Thank you for explaining this so easily

[@MedicosisPerfectionalis]

Glad it was helpful!

[@Roon864]

It’s my favorite channel 😍

[@suzannas.mathai6359]

3:33 "And baby you are on fire 🔥 " 😂😂😂

[@jenniferuller9852]

you, sir, are my hero thank you so much!

[@lindalolly6318]

I had 51 Rheumatoid factor after blood test, and doctor already said you have arthritis. They gave me midication and not helping, I ended up getting alkaline powder and thr pain is getting better, when its cold it's bad

[@andrewrood9200]

my rf is blank on my medical results so i dont know if ive got rf but my both knees are sore and ive got to limp when walking

[@sararose7812]

So happy to discover this magnific channel Thanks a lot Mzy god bless u

[@MedicosisPerfectionalis]

Thanks a lot for your kind words:)

[@DrMarwa-wq5oy]

Very big like am Very thankful for descovering your channel

[@MedicosisPerfectionalis]

and I am honored 😊

[@eyasalashi8876]

SERIOUSLY BRILLLLIANT ,PLEASE DON'T STOPPPP

[@MedicosisPerfectionalis]

I won’t! Thank you 😊

[@mohammedal-hammadi5085]

Your video is so good, but you explained the subject quickly and you passed several points

[@MedicosisPerfectionalis]

Like what?

[@mohammedal-hammadi5085]

for example "you are on fire disease", the disease may occurs because of releasing chemicals called cytokines which attack the cells of the synovial for example, and then synovial cells release another chemicals and then we get an inflammation

[@imadodeh1893]

Very nice way to explain this topic. I just have one comment : I know that ANA correlate with disease activity in lupus arthritis! So what do you mean in the last slide that ANA not correlate with disease activity????? Thank you so much

[@hananbasheer7720]

Your lectures just like piece of academic art

[@MedicosisPerfectionalis]

🖼 + 🧪 = Medicosis 😍😂😆

[@hananbasheer7720]

@@MedicosisPerfectionalis really nice really but please keep these videos free for the seek of god ... may god bless u

[@MedicosisPerfectionalis]

Thanks, dear...I will try my best.

[@julianfalciola5237]

Thank you for posting this video. I am in Australia. I have Rheumatoid Factor of 598 !! I have done an anti CCP test to check for Arthritis which came back from the lab with a score of less than 1 which excludes Arthritis. I am now entering my 3rd year of Chronic Fatigue Syndrome. No Doctor knows why I have this powerful fatigue for so long. The only thing really that they found was my FR being this highest anyone has ever seen. Does a highly elevated RF score cause Chronic Fatigue? If so how an I lower my RF?

[@shruthiaerroju4790]

Is this a big problem in married life?

[@julianfalciola5237]

Is Rheumatoid Factor elevated high in some one that has Mulitple Myeloma?

[@rare-gp8qq]

its realy cool when u said omg i am so good😂

[@subhenduberaa]

What is the rheumatic factor range which is negetive

[@unibrow9384]

Can rheumatoid factor be lowered?

[@prajaktaapte2521]

What if clinical presentation is of non inflammatory RA but ESR is elevated. No other inflammatory process is going on at least symptomatically.

[@eyasalashi8876]

YOU ARE AMAZING I LOVE YOUR CHANNEL , SO LOVELY WAY OF EXPLAINING

[@MedicosisPerfectionalis]

I appreciate you!

[@yannychiou282]

5:18 oh my gosh i watch those videos.... xD true they're mostly unhelpful haha! medicosis u really helped me improve so much in my class and i scored full marks two times this semester, and got 90+/100 in almost all other exams ! it wowed everybody (i used to be at the bottom of the class, failed 5 courses last year including hematology, but now I AM ENLIGHTENED!!! thank u so much medicosis, this is a lovely thing that you're doing!

[@yannychiou282]

i'm studying for medical lab science and biotech btw! and you have a video on every topic I come across...! it just makes me tear up when I struggle then see your video on my topic!

[@MedicosisPerfectionalis]

I am so proud of you 👏

[@yannychiou282]

@@MedicosisPerfectionalis :))))!! I will keep going!!

[@akshtshenoy2251]

my dad 74 year old.he has 124.0 in blood test ..can it reduce if take treatment?

[@submitteddtrofzion8096]

My Rheumatoid factor is +1400 and that’s as High as the test can go. This has been confirmed twice ont test. My PCP and rheumatologist both said I have the highest rheumatoid factor they’ve ever seen in their careers.

[@unibrow9384]

How are you doing now?

[@submitteddtrofzion8096]

@@unibrow9384 doing great. Stopped ALL their meds, refused anymore chemo. Take all natural remedies. Went from barely able to walk to Actually driving tractor trailer With my husband now.

[@unibrow9384]

My comments are being deleted.

[@unibrow9384]

@@submitteddtrofzion8096 Hey, idk why my comments are being deleted. I have added my m a i l in one of my most recently posted video's description. Could you please contact me?

[@Carlos-fh8wk]

@@submitteddtrofzion8096 amazing !!! Covid seems to have triggered my Rheumatoid arthritis. Never had this before. What did you take (natural remedies) to make it so much better. I’m in constant pain. Thanks

[@shruthiaerroju4790]

Any problem to have pregnancy with this health issue? Can you suggest remedies to maintain daily activities.

[@xxamulyaxx]

great content... love from INDIA

[@MedicosisPerfectionalis]

Love ❤️

[@subashkhadka6042]

Your Humor is out of world ... Its too funny!! and content i think i shouldn't talk about such a great thing...

[@MedicosisPerfectionalis]

Thank you so much 😊

[@hannahyost9798]

I’m positive Ana and igm. Trying to learn as much as I can.

[@MedicosisPerfectionalis]

I wish you all the best!

[@rachapudisakuntala5880]

Love you so much sir Really awesome teaching

[@MedicosisPerfectionalis]

Thank you 😊

[@salmael_badry2926]

I'm listening to records of a doctor from Al-Azhar university. He uses another mnemonics for cold and warm antibodies, which are: Cold= مِسَقّعَة (thus it's IgM as the word starts with the letter م) and Warm= جهنم (thus it's IgG as the word starts with the letter ج). 😂

[@MedicosisPerfectionalis]

Haha 😂

[@sanjibdahal254]

Funny entertaining and awesome 👏👏

[@MedicosisPerfectionalis]

Thanks a million 😊

[@wejdanalfahaad7910]

I like it, thank u man🤩

[@MedicosisPerfectionalis]

My pleasure 😇

[@KK-tb9of]

I like you a lot, your perfect way of explanation and funny sweet soul. Am in !

[@MedicosisPerfectionalis]

Thanks a ton!

[@bepilc]

Thank-you for sharing!

[@MedicosisPerfectionalis]

My pleasure 😇

[@oumamaderkaoui6130]

I love your method 😂

[@MedicosisPerfectionalis]

Thanks 😊 Can you please help me by sharing?

[@rittenbrake1613]

0:50 “oh my goodness I m so deep”🤣🤣🤣dead ,yea bro u r so deep

[@MedicosisPerfectionalis]

Thanks 😂😂

[@rockycycle2682]

here's the mnemonic that i heard from Dr Sattar (Pathoma; it's warm in 'G'eorgia and cold in 'M'ichigan

[@MedicosisPerfectionalis]

But it’s also cold in Greenland and warm in Mexico...So...? 🤷‍♂️

[@HA-sk8wh]

Hello Sir, my RF is 56 but all the other tests are negative, i do have pain in my joints but not severe. My appointment is too far and i bit scared.

[@sarahsmith3296]

same. did you end up having RA?

[@mdgp826]

first thanks for this video why dont we then consider TB for example as an autoimmune disease just because RF is positive and according to what you mentioned that is why RA is an autoimmune?

[@MedicosisPerfectionalis]

Positive RF is not the definition of autoimmune disease. Also in TB, we know the cause, it’s a bacteria (myobacterium tuberculosis) that triggers the immune system.

[@giamariecacocortez7402]

I KNEW I HAD TO CLICK THAT SUBSCRIBE BUTTON WHEN U MENTIONED MEMORIZING!!! T_T

[@MedicosisPerfectionalis]

Thank you :)

[@lilianajimenez3357]

Why ANA titer has to be 1:80 to be considered as positive?

[@MedicosisPerfectionalis]

High enough to be clinically significant

[@mdmahmudulhasan2303]

Very informative

[@MedicosisPerfectionalis]

Thank you so much!

[@dragosionutbratosin3291]

thank you!

[@MedicosisPerfectionalis]

My pleasure 😇

[@potatolover5778]

I have been having symptoms of Rheumatoid arthritis. I go to the doctor sometime this week and I'm really scared. I'll update you guys after I see the doctor.

[@MedicosisPerfectionalis]

Sure! Good luck! Please don’t be scared.

[@manvis6046]

How are you doing now. I hope you are good

[@potatolover5778]

@@manvis6046 I haven't gone to the doctors yet but I will soon. My joints really hurt though

[@ambarfeliciano5395]

What test is done to determine if there is rheumatoid factor?

[@MedicosisPerfectionalis]

A blood test.

[@ambarfeliciano5395]

Elisa test? Ana?

[@muhiyodinali2426]

Thank you

[@MedicosisPerfectionalis]

My pleasure 😇

[@sarahjanelinden]

if you have Gout will it show in RF test?

[@MedicosisPerfectionalis]

It might, but a positive RF is not a confirmatory test for gout.

[@dinoclasher4129]

Why is it made in the first place ?

[@dudesayHEY]

I had a blood test done and Rheumatoid Factor is 17.3 :/

[@kabitamitra9142]

Mine 20

[@KK-tb9of]

Last month only i suddenly got very high RF = 400 !!!! with sudden joint pain..... Am a doctor. Am shock ! And very very sad and afraid !

[@MedicosisPerfectionalis]

Talk to your doctor

[@ANURAGSAINI31OCT]

Sir my RA factor = 119 Sir can you please tell me what should i do So that it should not increase further Plzzz reply sir 🙏🙏🙏🙏🙏🙏

[@MedicosisPerfectionalis]

No one can diagnose you based on 1 lab test. You need to see a good doctor who can take a history, perform a physical exam and order lab tests to see the whole picture and know the cause of high rheumatoid factor. I wish you the best!

[@ANURAGSAINI31OCT]

Medicosis Perfectionalis thanks for the reply sir 🙏🙏 Sir but i have 1 more question = what is the normal value of RA factor in a normal human being ? Plzzz reply sir

[@jaspreetkaur8209]

@@ANURAGSAINI31OCT 20

[@ANURAGSAINI31OCT]

Jaspreet Kaur what do you mean by 20 ?

[@ramniwaskumawat28]

Hello anurag Same problem here What I do suggest me plz

[@gamaltaher9714]

Thanks

[@user-ig1ho9it7o]

Execuse me, why their is no videos for explanation of SLE?!

[@MedicosisPerfectionalis]

Coming soon

[@ambrishgok]

Can Vitamin D level of 10.7 and Vitamin B12 level of 102 lead to An Increased RF to 82? please answer

[@MedicosisPerfectionalis]

I have never heard of that!

[@ramniwaskumawat28]

Hello sir NAMASTE I AM FROM INDIA my rumetoid arthritis value is 1.82 What I do Pain in finger joint Please suggest me .

[@MedicosisPerfectionalis]

What do you mean by “rheumatoid arthritis value”??

[@ramniwaskumawat28]

@@MedicosisPerfectionalis I chake my blood sample for Rheumatoid arthritis ,the diagnosis describe.... Bio chemistry 1. Rheumatoid Arthritis- 1.82 IU/ML 2. C.R.P. (QUANTITATIVE)- 1.4 MG/L HEMATOLOGY EXAMINATION 1. ERYTHROCYTE SEDIMENTATION(ESR- WESTERGREN METHOD)- 62mm fall 1st hr. Please suggest me what I do.

[@tim9144]

Wtf causes high RF?

[@tesfalem9566]

Please am sick but we teak medicine indomethacin capsules use 25mg

[@tesfalem9566]

Can you tell me another medicine

[@nargizsafarova6595]

so rude... trotzdem ich liebe deine Videos....ich finde die hilfreich. Jede Tag versuche ich, ein oder zwei von ihnen zu schauen und überlegen und erinneren.

[@VJPILANIA]

Any Madison for RF POSITIVE SIR

[@MedicosisPerfectionalis]

????

[@ThatsWhy-]

What is psoriatic and rheumatic arthritis? Please

[@MedicosisPerfectionalis]

I have videos about them in my “Rheumatology” playlist.

[@ThatsWhy-]

@@MedicosisPerfectionalis i do not know the meaning of psoraisis? As aword in arabic it means sadafia or sodaf or sadaf!! What is this word?!

[@farisalmiqdad7146]

Watching a dog chase its tail IS fun

[@MedicosisPerfectionalis]

☺️☺️

[@hughhandy5407]

youve got some video in between your ads sir

[@docjey2em508]

Can you kindly send me your references on this? Thank you in advance

[@MedicosisPerfectionalis]

I use Harrison’s and Goldman-Cecil textbooks

[@docjey2em508]

Thank you

[@MedicosisPerfectionalis]

My pleasure 😇

[@nurannisanatsircaronge2360]

lowkey giggling because of your dad's jokes

[@MedicosisPerfectionalis]

:)

[@sakhilasudarsan858]

Luv dis vdio

[@MedicosisPerfectionalis]

Thank you so much 😊

[@madhavipakhale6622]

If it is negetive and esr is raised

[@MedicosisPerfectionalis]

The doctor will decide. No one can diagnose you over the internet using 2 lab results. Stay safe! Good luck

[@ramniwaskumawat28]

Hello dear Sister Same problem here. What you do please suggest me

[@samuraijack7745]

🥰🥰🥰

[@MedicosisPerfectionalis]

:)

[@codrut913]

😻

[@MedicosisPerfectionalis]

Thank you 😊

[@JeanAbdo]

Seriously, 3 ads on a 12 minute video (which was great, granted) why not put in 7 more? Just sayin' :)

[@courtney453]

0:48 omg im so deep!

[@hg-yj4hv]

Lol "No honey you didn't"

[@MedicosisPerfectionalis]

Exactly 😉

[@vijaysimms4759]

"oh my goodness im so deep"

[@TechKnowlogee]

All newly graduated pharmacists are doctors. Physicians aren't pharmacists and pharmacists aren't physicians. It is good to consult with many specialties whenever the opportunity is present. Not a good idea to throw shade at the pharmacist.

[@MedicosisPerfectionalis]

I was joking 🙃 I make fun of doctors, and dentists as well in many of my videos!

[@soniatee8458]

you're funny. i like you

[@MedicosisPerfectionalis]

Thank you ☺️

[@user-rl5tz1kf7n]

your definition for sensitivity is wrong !!!

[@allamalik4209]

God help u💔😂 Ur just cute

[@allisonjohnson4606]

There were definitely less extremely rude ways to say that a pharmacist/lab technician shouldn't diagnose you but ok. As a pharmacy student, I know that diagnosis isn't our expertise, but "GOD HELP YOU" was unnecessary :(

[@MedicosisPerfectionalis]

I was joking 🙃 I like pharmacists!

[@madjdabouglam189]

OMG I’m so deep 😂😂😂

[@MedicosisPerfectionalis]

Haha 😂

[@codrut913]

[@tiffanyh282]

Yeah...you just lost me at "not a pharmacist, God help you". I'm a pharmacist. Maybe you should call out one single name of a pharmacist who you know for a fact that's done that instead of all of us. Otherwise, you'd just be one of those "idiot doctors" that we also hear about.

[@MedicosisPerfectionalis]

I was joking 🙃

[@tiffanyh282]

@@MedicosisPerfectionalis oh. were you? So was I. No I wasn't. You're hilarious. 🙄

[@yoshtisune]

Cringe

[@chingatumadregoogle1344]

Dammed I am not even studying medicine i just want to be a medical interpreter but hell you make it so clear and complete. Best underrated channel. 😂

[@MedicosisPerfectionalis]

Thank you so much!