Рет қаралды 27,288
00:21 Tissue Damage Activates Fibroblast to release Inteluekin-25 & Interleukin-33
00:30 Inteluekin-25 Activates Type 2 Innate lymphoid cell to Release Inteluekin-13 & AREG
1:05 Complement Pathway Activation.
1:50 Inteluekin-13 Attracts Mast Cells and are activated by Interleukin-33 and Component 5a to release Histamine
2:00 Inflammation
2:25 Staphylococcus Aureus evades the Complement System
3:00 S Aureus Cell Wall Anchored Proteins (Protein A, SasG, Isd, Collagen Adhesin)
3:17 Collagen Adhesin Mechanism
3:51 Phagocytes (Neutrophil & Monocyte)
4:03 Phagocyte Chemotaxis Pathway
4:45 Phagocytosis and Respiratory burst on Phagosomes.
5:40 Neutrophil Extracellular Tramps (NET's)
5:55 Macrophage
6:12 Toll-Like Receptors Activates Macrophages to release Interleukin-6, Interleukin-12 & Interleukin-23.
6:34 Interleukin-23 Activates Type 3 Innate lymphoid cell to release Neutrophil attracting chemokines, Interleukin-17 & Interleukin-22.
6:50 Interleukin-17 Activates Fibroblast to release anti-microbial peptides
7:02 S Aureus Biofilm
7:40 polysaccharide adhesin Synthesis
9:00 Quorum Sensing
10:06 S Aureus Virulent Factors (CHIPS, Hemolysin, Leukocidins)
REFERENCES:
📗 Biochemistry 4th
👨🔬 Donald Voet, Judith G. Voet
-------------------------
📗 Molecular Biology of the Cell 6th
👨🔬 Alberts, Johnson, Lewis, Morgan, Raff, Roberts, Walters
-------------------------
📗 BROCK Biology of Microorganisms 13th
👨🔬 Madigan, Martinko, Stahl, Clark
-------------------------
📗 Netter's Essential Histology 2nd
-------------------------
📗 Introduction to Human Physiology 8th
👨🔬 Lauralee Sherwood
-------------------------
📗 Janeway’s Immunobiology 9th
👨🔬 Kenneth Murphy, Casey Weaver
-------------------------
📗 Robbins Basic Pathology 9th
-------------------------
📰 Adhesion, invasion and evasion: the many functions of the surface proteins of Staphylococcus aureus
📰 Bacterial Two-component and Hetero-heptameric Pore-forming Cytolytic Toxins: Structures, Poreforming Mechanism, and Organization of the Genes.
📰 Commensal StaphylococciInfluence Staphylococcus aureus Skin Colonization and Disease
📰 Innate Immunity to Staphylococcus aureus: Evolving Paradigms in Soft Tissue and Invasive Infections
I use Painter Corel to do the drawings and After Effects to Animate the scenes.