RNA modifications: 5 prime cap

[@AnimeUni-versed]

You are very knowledgeable and your explanations are super clear. Thank you for the dedication ! Have a blessed day !

[@shomusbiologyofficial]

Glad to hear that you are getting benefit from the videos

[@manviaggarwal5358]

Thank you so much Sir..... It's my pleasure I have u as a tutor ...when I needed.,...

[@shomusbiologyofficial]

Thank you. Glad u liked my lectures. Stay subscribed!

[@nadjalapoint8336]

incredible explanation thanks so much for posting!! very concise and easy to follow, maybe I'll actually pass this mol bio exam haha

[@shomusbiologyofficial]

You're welcome

[@aabhaghoradkar6453]

I m read this topic since last 2 hours in my book but i can't understand anything from book as soon as i see ur explaination my topic is very clear within 20 min thank u for always there for us sir😊

[@shomusbiologyofficial]

Glad to hear that you're getting benefit from my lectures

[@mashallahtube3084]

are VITian? I mean VIT university??????

[@aabhaghoradkar6453]

@@mashallahtube3084 no i m from Nagpur University

[@rizwanullah6467]

What is the name of that book plz tell ....

[@ayyuen]

I prefer your videos in this style which are more clearer than the picture ones.

[@prabirsbiology8220]

Why guanine is used in capping in m RNA besides other. Plz reply. It is very helpful to me.

[@m.sc.partiibiotechnologysi1546]

mol bio should be taught like this .... brilliant work !!!

[@shomusbiologyofficial]

+MSc Part 1 thank you.

[@exploringworld5860]

Shomu's Biology this is very old vdio..maybe when you were a beginner but still ur skills of teaching was very nice.and now it became best.u r doing ur job in very smart way. thank you so much sir.

[@nooriyajameel8035]

Can you please tell me that why capping is only done with guanine?? Why not with other nucleotides?? I have searched enough but didn't get any answer to this

[@Ashishsingh-ls6zh]

Hope i had teacher like u sir...u explained well..

[@shomusbiologyofficial]

You're welcome. Glad to hear that you're getting benefit from my lectures

[@chaschassasafras8700]

You don't explain how the first base in 5' in mRNA loses one phosphate group. The 5'-5' linkage contains one phosphate from the GTP and 2 from the base in mRNA. However, this base originally contains 3 phosphate groups. How does it lose the third phosphate group?

[@ahmadal_shanqeety802]

By an enzyme "RNA triphosphatase" which cleaves the third P of the growing RNA leaving only diphosphate

[@rkcraft2550]

Why there is used only GTP not any other for capping?

[@swarnabhasarkar8702]

Sir... I've a question... The α phosphate of the incoming dGTP and the α and β phosphate of the 5' RNA end is getting attached... Right?

[@angrybird1432]

U r great sir u clear all concept so we don't have any doubts 👍👍 thanks again 🙏

[@shomusbiologyofficial]

You're welcome. Glad to hear that you're getting benefit from my lectures

[@muhammadwaqar648]

sir by adding 5cap to messenger RNA we can only protect from exonuclease but how can we protect RNA from endonuclease at the middle cleavag

[@stephaniemanganello2139]

Thank you so much. Your explanation was so helpful!

[@shomusbiologyofficial]

You're welcome

[@dikshaapadhi1285]

Hello! Could you kindly make a video on the Role of RNA modifications in cancer. It will be really helpful.

[@biologicalresearch5836]

I am yr old fan, no word cn justify yr work.

[@shomusbiologyofficial]

Thank you

[@manibashar2739]

THANK YOU !! That was amazingly explained !

[@shomusbiologyofficial]

Thank you for watching the lecture

[@omniamohamed404]

Why do the original nucleotide of 5 prime end have 2 phosphate groups? 13:02

[@lonesurvivor5214]

Sir u r inspiration for us 🙏🏻

[@shomusbiologyofficial]

Thank you

[@ElafTaleb]

Didn't think I'd actually find a good explanation on this.. Thank you!!

[@moahhed121]

Powerful explanation!

[@binduu19]

hello sir.I have a doubt in synthesis of eukaryotic mRNAs by RNA poly 2 I don't understand.. I just understand d process of termination...will u pls explain the process before termination...that is initiation and elongation....

[@sheeezashoukat6068]

Amazingly explained .. Thnku

[@shomusbiologyofficial]

You're welcome

[@princessjui5087]

i am glad that i subscribed this channel and having such an amazing tutor like you . God bless you brother :)

[@mampidutta327]

Princess Jui

[@gopikrishangaur1867]

The way u silent ur family members is quite...interesting...🤣😂

[@patitpaban5542]

Why G is only used in capping?

[@sikhapanigrahi826]

Sir sometimes two guanosine residues are added instead of one.. Please explain it.

[@hillapeernissan3963]

wowww you are the best teacher ever !!! thanxxxx

[@sikhapanigrahi826]

Sir, you told two phosphates are released. But in the book,it is given that one phosphate is removed by the enzyme phosphohydrolase.

[@rizwanullah6467]

What is the name of that book plz tell

[@markjuanico9540]

you really helped me a lot man! thanks

[@hamsinikaruturi4653]

Then where does that third phosphate go or how it is released from first base of m.rna ?

[@Banilicious89]

thank you so much, your explanation was very good and i understood everything whereas in class i was lost and i read the textbook and re-read my notes but didn't make sense. thank you

[@kochutheresaa]

why G is used in capping?

[@omniamohamed404]

What is the difference between Guanine and Guanosine?

[@duebelknuebel]

Thank you very much! Very helpful and on the point. greets from Germany

[@brakstrongarm9551]

This was really good thx. Just found your video's I am off to check some more out now and subscribe:)

[@shomusbiologyofficial]

Thank you. Glad you liked my lectures

[@EarthC1_37]

Great sir🙌🏼🙌🏼

[@shomusbiologyofficial]

Thank you

[@samerghanem599]

very precise, great explanation

[@michellewong3813]

thanks! your lectures are really useful!

[@alfredomunoz8791]

Is this addition of a 5’ cap modificationfor eukaryotes prokaryotes or both?

[@shomusbiologyofficial]

Eukaryotes only

[@valeriefernandez7628]

Thank you so much! Very helpful

[@shomusbiologyofficial]

Thank you. Glad you like my lectures. Do subscribe.

[@Vishal5171]

Sir capping process is cotranscriptional...

[@jyotichandan01]

Thanku sir ....it was really vv helpful...amazing

[@shomusbiologyofficial]

+Jyoti Chandan you're welcome

[@kishan1851]

Apart from the hilarious accent and your mom's intrusion, this was actually very informative. Thanks a lot!

[@juliawocyrus7577]

Great explanation....thanks

[@kpriya7186]

Plz vedio on biochemistry of methanogens with there reaction tnd steps

[@chatpatabullet...3172]

Nice explanation😊

[@MXS1412]

Thank you! It was so helpful :')

[@ولدالجنوب07-ب1و]

ياميمو ممكن من وقتك بضع دقايق

[@hasankuliyev4211]

is in Base 1 initially three phosphates instead of two that u said

[@Divyajyoti__]

Thank you sir🙏

[@shomusbiologyofficial]

You're welcome

[@SharonKu626]

3:45

[@geparada88]

Nice! But mRNA capping is not post-transcriptional, but rather co-transcriptional.

[@dianagh8812]

best video ever

[@shomusbiologyofficial]

Thank you

[@lenakanaaan570]

Please add caption subtitle

[@sayanidas170]

Thank you sir

[@shomusbiologyofficial]

You're welcome

[@justafangirl3902]

Thank you so much sir🙏

[@mampidutta327]

it helped a lot. .. suman

[@saurabhpachauridlp7290]

Please sir hindi me bhi video send keeya kro plz plz plz plz. Sir

[@siniduzegeye5556]

gr8 job. an love it tnxs a lot

[@nirvana2172]

fabulous! very detailed ! thankyou!

[@ajithkumarvs8819]

Super classs.....

[@meerpeya5139]

thank you sir....

[@shomusbiologyofficial]

+Parveen Akther you're welcome

[@ayaqz3144]

thank youuuuuu

[@shomusbiologyofficial]

You're welcome

[@22rnd]

amazing !!! congratulations!!!!!

[@creativitybybee7047]

Good work 👍🏻 👍🏻 👍🏻 from 🇵🇰

[@shomusbiologyofficial]

Thabk you

[@raginirajput2348]

what is exonucleus?

[@biologicalresearch5836]

Ability of polymerise enzyme to remove the wrongly incorportaed nucleotide .

[@tasbeehashraf1810]

Thanku soo much

[@shomusbiologyofficial]

You're welcome

[@priyak6945]

Thanks sir

[@shomusbiologyofficial]

You're welcome

[@subhramaniyamswami3893]

Great sir

[@asinjitdas3113]

So nice yarrr

[@muhammadtahir-bf9lp]

good sir

[@sreenivasareddyavula5624]

nice and super

[@Barfijalebi]

🤫🤫 koi enter kra room me..🤭🤭

[@danieleiann6175]

great

[@christophp.861]

Super!

[@Nirupama-tp1jp]

Thank you sir

[@shomusbiologyofficial]

You're welcome

[@harmeetsingh7894]

Thank you sir