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In this video, Dr Kamal Singh speaks about Vasopressin hormone, also known as Anti-diuretic hormone, its role in body, clinical uses etc.
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Vasopressin, also known as antidiuretic hormone (ADH) or arginine vasopressin (AVP), is a naturally occurring hormone crucial for regulating various bodily functions, particularly in maintaining the volume of water within the extracellular fluid surrounding cells. Originating from nerve cells in the hypothalamus at the base of the brain, vasopressin is transported to the pituitary gland, which releases it into the bloodstream.
The primary role of vasopressin is to facilitate water reabsorption in the renal tubules of the kidneys, thereby promoting water retention and reducing dehydration. Additionally, it contributes to increasing blood pressure through vasoconstriction and augmenting blood volume.
Beyond its physiological functions, vasopressin regulates the circadian rhythm and helps maintain the body's internal temperature. Psychologically, it influences cognitive processes such as attention, learning, memory formation, and emotion regulation, while also modulating social behaviors, particularly in males.
Various stimuli, including pain, stress, certain diseases, and specific drugs like narcotics, can trigger the release of vasopressin. When vasopressin reaches the kidneys, it signals them to conserve water, resulting in the production of concentrated urine. This water retention affects the body by diluting blood, lowering blood osmolality, increasing blood volume, and consequently raising blood pressure. Thirst is also stimulated as a supplementary mechanism to restore water balance.
Disruptions in vasopressin levels can lead to health conditions such as diabetes insipidus and syndrome of inappropriate antidiuretic hormone (SIADH). Diabetes insipidus manifests as excessive thirst, frequent urination, and dehydration due to inadequate ADH production or kidney insensitivity to ADH. In contrast, SIADH results from excess ADH secretion, causing water retention, dilution of blood, and low sodium concentration.
Treatment for these conditions involves fluid restriction, hypertonic saline, diuretics, or vasopressin receptor antagonists like tolvaptan. In severe cases, surgery may be necessary, especially if a tumor is the underlying cause. Synthetic vasopressin is also used clinically to manage conditions such as diabetes insipidus, bleeding disorders, esophageal variceal hemorrhage, asystolic cardiac arrest, and septic shock.
ADH हार्मोन का दूसरा नाम क्या है?
vasopressin इंजेक्शन किसके लिए प्रयोग किया जाता है?
ADH हार्मोन कौन स्रावित करता है?
वैसोप्रीसीन हार्मोन की कमी से होने वाला रोग कौन सा है?
वैसोप्रेसिन हार्मोन की अधिकता से रोग?
वैसोप्रेसिन हार्मोन का कार्य क्या है?
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