Seroquel (Quetiapine)

Dr. Pagnani of Rittenhouse Psychiatric Associates discusses Seroquel (quetiapine) a second generation antipsychotic (SGA) that is FDA approved to treat anxiety, bipolar depression, bipolar mania and schizophrenia. It can be a very effective medication but also can have several side effects, some of which are discussed in this video.
Dr. Pagnani is the founder and medical director of Rittenhouse Psychiatric Associates, an Instructor at The Johns Hopkins Hospital for the Department of Psychiatry, he supervises psychiatric residents at Jefferson Hospital, he serves on the Young Professional Board of Uplift, the Center for Grieving Children and he maintains a private practice of Psychiatry in Philadelphia where he sees patients for one-time psychiatric evaluations and second opinions. He is a licensed physician and surgeon in NJ, PA, NY, MD, DE, FL and CA and can provide consultations to individuals via HIPAA compliant Telehealth visits living in these locations.
Rittenhouse Psychiatric Associates is a private practice of psychiatry consisting of about 25 psychiatrists, psychiatric nurse practitioners and psychotherapists with physical locations in Philadelphia and Paoli, PA and serving all of PA, NJ, NY and FL virtually via HIPAA compliant tele-psychiatry. Individuals seeking not only evaluations but long-term psychiatric care, can contact Rittenhouse Psychiatric Associates directly.
These videos aim to increase awareness and discussion of mental health topics and to encourage struggling individuals to schedule an appointment directly with a mental health provider. Mental health needs to be normalized, and simply speaking about mental health topics openly, is an important first step.
Dr. Pagnani and Rittenhouse Psychiatric Associates are NOT advocating for or against the use of any mentioned psychiatric medications for any specific individual. Additionally, any side effects mentioned are not a complete list of potential side effects or contraindications to taking any mentioned medications, and all risks and benefits of a medication should be discussed with an individual’s provider at an appointment, before starting, stopping or making changes to a medication regimen.
This video is INFORMATIVE ONLY - NOT MEDICAL ADVICE.
If you are researching a specific topic, please view our KZbin channel, click all videos and use the search function. Please also visit and follow us on instagram and FB: @RittenhousePsych.
www.RittenhousePA.com
www.ChrisPagnaniMD.com

[@messengerdestroyer1856]

I am on 200mg for bipolar 2. For side effect, I have blocked nose. No worries..just use nasal spray. Best part of this med is that I sleep peacefully. I am less irritable, angry and more self aware. 3 years now. Better quality of life and self determination. My 2 cents worth.

[@kira_x-ray]

You can but use nasal spray longer than a week, then you should stop or you’ll become addicted to its effects.

[@KirkAl-lq7tc]

@@kira_x-raythat’s Afrin

[@Royalfaction]

I can listen to you talk all day

[@DNYS8N]

I am taking 150 mg extended release and here’s my deal. Sedated 24:7, very poor motivation, (zombie shuffle), increase appetite, weight gain. The sedating effects has little wear off through our day. Improved my mental health issue Basically killed my motivation to do fun stuff. Barely if ever play music or do hobbies anymore It’s like I have a why bother attitude for anything other than work or grandkids. Barely walk the dogs, it’s not a fun life but it’s calm

[@garynelson9538]

Wow I didn’t know there was an extended release prescription. I need that one.

[@cgx11g21]

Lol hello Just lower it to 25 mg is tons...! I used to break a 25mg in half! And could feel 15mg Even.. helped with sleep. Your zombie for a Reason. Don't be stupid. Try 50mg or better yet 25 mg.

[@wandahaas7935]

If you take it in the morning, that's your fault for being dumb

[@joyfullone3968]

I take Seroquel for Bipolar 1 and it has been a life saver and kept me out of the hospital. I have gained weight though.

[@gabriellerivera9424]

I am not gaining weight. I'm trying to reach 120lb for 4.1 ft.

[@gabriellerivera9424]

I'm 115lb and 56 years old

[@EnricoTurco-xy7jk]

Thankyou.

[@tatyanasmith855]

Doctor my stepdad is 67 he took this and he didn’t sleep. He was agitated and aggressive towards my mom and wanted to hurt someone. He is in the hospital now for evaluation. Why did this happen?

[@davidmayhew8083]

I have a friend with bipolar disorder who was recently taken off of lithium after that had worked for years. They did this because of a heart issue that developed. His anxiety level skyrocketed. He was put on Seroquel and propolanolil and Ativan. The Dr. stopped his Ativan and is now allowing him extra Seroquel mid day to quel his anxiety. But he's taking more than suggested to stop the anxiety. He's now taking 50mil at night and 25mil mid day. Is this too much? Wiki has no dose info. He can't ride out the anxiety. Should he be put on a Benzo for anxiety? We know it's addictive. But he's 70 years old. Perhaps it would be ok to manage a Benzo carefully. I'm afraid of this keeps up he will kill himself.

[@karlasnyder645]

Seroquel gave me a psychosis. Scary experience.

[@TreCayUltimateLife]

please share your experience

[@karlasnyder645]

@@TreCayUltimateLife my doctor recommended for me to take seroquel at bedtime with my sleep med because that would also make me feel “sleepy” and “drowsy”… well i took it at night. I was walking in my kitchen when suddenly i start to see patterns. I knew they werent real but i didnt know what was happening. I went outside and sae the same patterns on the floor, i looked up and saw bugs crawling. I knew everything wasnt real but it was shocking and scary. I didnt know what to do and was thinking why would this happen… i didnt want to call 911. I then forced myself to throw up in the bathroom. I took a joint from that i had purchased from the smoke shop to calm me down. I was smoking it and called a friend and told him to stay on the phone with me and if i stopped talking to call 911. It took some time to wear off but it made me so scared. When walking i kept looking forward because i didnt want to even see more from the sides. I was extrnely terrified and in shock. I will never touch seroquel.

[@yasirpanezai5690]

Not possible

[@karlasnyder645]

possible because it happened, do your research.@@yasirpanezai5690

[@aaronlawson6551]

It's not right for everyone, but it helps me sleep and it really can be a Godsend.

[@GriffyP-qo4xs]

On 25mg 2 times a day , does anyone have insomnia at night and night terrors? And groggyness during the day (probably from lack of sleep)

[@yasirpanezai5690]

Seroquel is the best drug for drug addiction and stimulant psycosis

[@crystalmcculloch9083]

Hopefully this doctor sees my question. I take 50 mg xr for sleep. I wanna xome off of it been on it for 4 years. Why cant u cut the seroquel xr in half. I get that it has a coatimg for extwnded release but if you cut it iant it like being on the immwdiate release version? Ive tried the immediate release veraion and i enedes up having a panic attack. Od rather cut the xr. My psychiatrist has told me just to stop the 50 mg because its the lowest dose. But I want to wean. And id rather cut the xr version. Why is it dangerous if i just want to wean. I feel tired the next day from the xr even though its only 50 mg. She also said she doeant know if you can cut it and if a pharmacist said I could then go for it. But what am I in fo rif i cut seroquel xr 50 mg. Anything. ? I dont care if it turns into immediate release. Its a pill I know and would rather do that then take the actual immediate release because of my experience in tje past with IR.

[@wildgeraas7187]

12 days ago I reduced the quetiapine dose from 100 to 75 mg., 3 x 25mg per day I couldn't sleep for 6 days and had constant anxiety. Now every time I take the medication I start to feel anxious, restless and agitated after an hour. When the medication reaches its half-life after 5 to 6 hours, I become calm again. How can it be that This is logically part of the withdrawal symptoms!? Shouldn't the symptoms be the other way around.!?

[@garynelson9538]

Are you taking it during the day time or night before bed??

[@ryantimm9748]

I take 300mg once a day at night and it has absolutely been a life saver. I have bipolar 1 and pretty bad anxiety so sleep is very elusive to me, and seroquel not only has treated my insomnia and let me get a good 8+ hours of sleep, it helps regulate my bipolar. I don’t have very many episodes of mania or severe depression but maybe 2 times a year. The ONLY side effect I’ve had is that is affects my ability to regulate body temperature so I can become overheated very easily and feel like I’m going to faint if I overdo it physically. Taking all that into consideration the benefits that I receive from the medication absolutely outweighs the one side effect I have. I have also tried rexulti and Abilify but had terrible weight gain and cravings. So seroquel has been a game changer for me that treats SO many symptoms I was experiencing. 10/10 would recommend for anyone with bipolar 1, moderate to severe anxiety, and insomnia.

For me was a disgrace. From 300 mg then 200, 100, 50, 25 and 6 mg. Worsens my blood pressure among converted me in a sleepy Zombie. Tragic experiencia. Saludos desde Patagonia Argentina

[@fruitbunnii]

Reviews online said it was “life changing”. But the comments here make me nervous to take. Anyone had a positive experience on 50mg?

[@harun1529]

More or less, you will sleep well but feel drowsy, i gained some weight but thats no prob for me since i was slightly underweight anyway, now I've tapered down to 12 mg and it wasn't scary, can sleep still ( 3 yo user)

[@David-m8i]

yes

[@yousefmohammad8534]

I've used this for a month 50mg 45 mins before sleep now it's day 4 for me trying to sleep without it

[@maxwellrankin917]

People with bad experiences are more likely to comment than people with good experiences. Same thing with people who leave reviews, usually you’re more inclined if you were left unhappy. Also these are missing a lot of context.

[@amandalove2657]

I just lost my husband a few weeks ago from complications of kidney disease. It wasnt expected and very tramatic. My doctor has prescribed me Seroquel and I'm terrified to take it. I am worried what it's going to make me feel like. Is Seroquel something that's normal to give somebody when they've been through a tramatic event, for sleep?

[@robanderson5921]

it helped me sleep so much and calm me. It saved me

To me was an horrid experience. To me...

[@GabiGulost]

for me it has helped allot.

[@user-be2yk7bq5q]

Hi, i am suffering with MDD since 20 years and also diabetic DM2 on Insulin, how safe is to take this medicine?

[@hoosierbaddy3052]

Shouldn’t be asking for medical advice on KZbin

[@user-be2yk7bq5q]

@hoosierbaddy3052 sometimes it will help

[@seanothepop4638]

People should be able to afford to get healthcare, they can't. Get ready to accept many people have to turn to media like this. Please be kind to the poor who do.

[@garynelson9538]

I was prescribed 300mg at night. Once it kicked in, I couldn’t walk up the stairs into the bead room. I went to 150mg and it also was hard to walk up the stairs, but with both doses the sleep was/is great.

[@j-uk2189]

What are your credentials, doctor?

[@brandonm8131]

25 MG for sleep is good? I was just prescribed today for insomnia.

[@edgarcardenas7303]

It was very good for me I sleep like a baby

[@GabiGulost]

I was prescribed 25MG for sleep. I tried 25MG and it did nothing, then I took 100MG the day after and fell asleep after 30minutes or something. but my doctor strictly told me not to go higher, so you should talk to your doctor first or something idk. now I use 100MG every night :) just a couple side effects

[@endyalfonso9801]

It’s not good it’s great!! 👍

[@brandonm8131]

@@endyalfonso9801 I think its dangerous. I was slurring, had vertigo, headaches etc

[@yoyoyo8011]

This drug almost killed my 86 (at the time of event) year old mother. It affected her heart critically. She ended up having the equivalent of a heart attack. She was standing in the living room blacked out because her heart malfunctioned and from a standing position fell over full force and hit the floor with her head so hard the whole side of her head was blue for a month (blue bruise started next day). I picked her up put her on the couch let her sit for 5 minutes and thought she ok. I told her to come into the kitchen and have breakfast I prepared for her. She came into the kitchen sat down and almost fell over again while sitting. I had to grab her to steady her. That’s when I called 911. Do your research online for this drug you’ll find it is “cardio toxic” and the death rate due to random cardio events is high.

[@gustavocarvalho1346]

Typically, older people need lower doses of medication in terms of risk-benefit ratio. Immediate-release quetiapine can be extremely uncomfortable in relation to the heartbeat. I'm young and had fall while going to the bathroom before sleep

[@blairsterling6141]

Doctor.. please answer questions. 1. Does the drug cause Tardive Dyskinesia ? 2. Does the drug cause NMS ,? 3. Does the drug cause akathisia? 4. Does the drug lead to diabetes? 5. Does the drug cause constipation 6. Does the drug cause abnormal movements permanently ? 7. Does the drug cause high cholesterol ? 8. Does the drug cause Ataxia ? 9. Does the drug render a person unable to speak ? 10.. Does the drug cause twitching of hands, feet, and other neurological destruction ? Thank you for answering. My husband needs to know these answers. Thank you.

[@florenceflorence6899]

You forgot the breast in men and lactation, losing g your teeth and hair and foolish pee smell very attractive for a better self esteem and well being indeed ,you forgot as well cognitive retardation ,because that's what everyone's needs to feel better of course and total loss of libido or pleasure which is all you need to feel a,waste of space and kill yourself, feeling constantly between the flu and a hangover state is not a life its torture that's disgusting actually deteriorate someone as such without any remorse ...who prescribes these are the guilty ones indeed

[@RittenhousePsych]

Seroquel (quetiapine) similar to all neuroleptics, potentially could cause tardive dyskinesia (although it likely has a much lower risk than most first generation (and many second generation) neuroleptics. It tends to be well tolerated, but it can potentially cause several of the side effects that you mention (such as increased glucose and higher risk of diabetes, constipation, and changes in lipids). Many of these side effects can be easily monitored with labs. If someone is concerned about possible side effects, I recommend speaking directly with their (or your husband's) provider to discuss risks and benefits of trialing the medication. Thank you for your question! - Dr. Pagnani

[@blairsterling6141]

@@RittenhousePsych Thank you. These devastating side effects are mentioned in one if the best books written about Psychiatry. Written by Dr. Peter Breggin, " Toxic Psychiatry " spells out the multitude of problems with any psychiatric drug. We LOVE 💜💙 Breggin for being truthful. We hate Psychiatry that is hiding truths, lying, and full of misinformation and false information. Again, we love Breggin. We suggest people begin to follow the truth tellers.

[@j-uk2189]

Yes, potentially all of these can happen.!

[@blairsterling6141]

@@j-uk2189 ..then. why not strictly follow the Hippocratic Oath !!! ??? 😡😡😡😡😡😡😡😡😡😡😡😡😡😡😡😡😡😡😡😡😡😡😡😡😡😡😡😡😡😡😡😡😡😡 "First, DO NO HARM !!" 😡😡😡😡😡😡😡😡😡😡😡😡😡😡😡😡😡😡😡😡😡😡😡😡😡😡😡😡😡😡😡😡😡😡😡😡😡😡😡😡😡😡😡😡

[@Ohkeh640]

Started 12.5mg quetiapine today twice a day for anxiety and panic attacks. Then will see if my Dr wants me on the full 25mg tablet… 1 week on mirtrazipine 15mg at night and today dr upped it to 30mg for sleep depression anxiety I’m worried this combo will make me gain weight! I’ll try eat how I do now. Not that often etc.

[@nenadcubric2663]

Does it help with Anxiety?

[@robanderson5921]

yes it does very much

[@louisegardenia7674]

I started lactating and lost my period and was incredibly itchy. It turned out that the tiny dose I took for sleep gave me a pituitary gland tumour that gave me menopause at 30, the endocrinologist said I had the hormones of an 80 year old. I had to take Dostinex to shrink the tumour and spent every weekend in bed throwing up from it. The first time I took seroquel I fainted in the shower, I was 22 and I phoned the doctor saying I don’t want to take this stuff. She told me I had to so I did what she said. She also put me on Effexor 150 and that eventually gave me seizures. Then Lexapro and that gave me seizures too. I now take a tiny dose of CBD and feel great and I sleep

[@shaniacoronado259]

WOW omg I hope you are okay, what alternatives did you use? I use it at night time to help me with thoughts and sleep well

[@louisegardenia7674]

@@shaniacoronado259 thanks I’m ok now. I went on Mirtazipine for six years but it has caused me histamine issues so I won’t take anymore psych meds. CBD is helping but I think acceptance regarding insomnia has been the best thing for me.

[@shaheennayfeh17]

Does it cause weight gain

[@Jessica.771]

It did with me but I need the medicine to function. I’m on 800 mg.

[@RittenhousePsych]

For some individuals Seroquel causes weight gain, but not for others. Typically if I assess that a patient may benefit from the medication, I may start it low and increase slowly, while monitoring for side effects. I do not know how you would respond, but this is certainly something to discuss with your provider. Best, - Dr. Pagnani

[@user-rh7zy1tj4m]

How much to take for depression

[@Letmebestupidpls]

If You’re not talking about bipolar depression than try antidepressants (sertraline, fluoxetine etc.) instead of

[@user-rh7zy1tj4m]

@Letmebestupidpls I have tried antidepressants but they don't work I am going to try Hrt

[@Letmebestupidpls]

@@user-rh7zy1tj4m Oh ok I really hope it works out for you!! This illness sucks

[@davidmayhew8083]

Or anxiety!

[@notme5909]

I know a lady that weighs 130lbs and her doctor gives her 300milligrams a day..

[@garynelson9538]

I weigh 280lbs and 300mg was too much for me.

[@gtrdk8205]

I have insomnia My doctor gives me seroquel 25mg. I slept better than benzodiazepines but I was constantly dizzy and changed my mood and personality. The withdrawal was like a horror story. Now I have 200% insomnia no sleeping at all 😢

[@RittenhousePsych]

Thank you for sharing, and I'm sorry to hear about your experience. Sincerely, - Dr. Pagnani

[@Ohkeh640]

Oh no how are you now ? Did you find anything that helped

[@theheaterguyryan5052]

Really!!! l experinced this also

[@Johnnash4678]

Are you Italian? Doctor

[@aigaoliveira3278]

???

[@blade8424]

Dr wants me on 25mg as a Mood Stabilizer and Generalized Anxiety Disorder and Panic Attacks. Last time I took it years ago was on a higher dose I think? That was back in 2011. He wants me on it for social anxiety, panic attacks and mood disorder. All it did was made me feel like a zombie. Didn't mess with my Mania at all. Just zombie mode and tired. How often does the zombie effect wear off? I took it during the day so he wants me to take it at night this time. I heard good reviews for anxiety disorders and it was given a 7.4 star rating. Hopefully it'll help my GAD, PTSD, Social Anxiety, etc. I have a hard time sleeping at night. Had a bad experience with Celexa. :( I hope this works better. All Dr told me it would make me tired and hungry. Sick of these panic attacks. I want to feel normal again. Anyone had any success with panic attacks??? Taking it tonight. Wish me luck. 🙏

[@Prathamjot__]

So nobody talking about the f*cking hallucinations?

[@j-uk2189]

Whats this doctors Credentials. I want evidence or gmc number? I will give you mine. I’m absolutely shocked that you’re promoting this drug for sleep issues. I would happily come on and debate this stupidity (risk vs reward) etc.

[@Gothgalactica]

Lmfao you’re freaking out over nothing. Seroquel was pxd for me for my sleep troubles. Literally I’m fine. You’re paranoid dude chill out and get a hobby

[@victoria653]

He is simply talking about the uses, not so much promoting?

[@adhamah1138]

experiment

[@adhamah1138]

mkultra