Should You Take Weight Loss Drugs?

[@lightningq61]

I really love how compassionate and persuasive Mike’s takes are. He mentions his interest sometimes in principles of logic and debate, and it genuinely really shines especially in videos like this where he manages to come off as sympathetic to any given side of the topic while thoroughly disagreeing with their conclusion and presenting extremely well thought out arguments. I feel like he does a great job modeling professionalism and I’ve learned a ton from this content both in terms of the direct information and like just being a better citizen in a sense

[@RenaissancePeriodization]

Thank you so much! I'm trying! - Dr. Mike

[@jacerajkowski9330]

i was just going to say that he's awesome cause i wasn't sure how to put that into words ^^ but yeah!

[@gabesaenz9837]

He seems like a genuinely decent human being, and I get the impression that even when the camera isn’t there, this is him

[@Naanofurbusiness]

Damn that really changed my perspective on things. So I guess I’m a bit of a hater of people who use these drugs. That said, would love to hear more rants.

[@springsteen-games5134]

@@RenaissancePeriodizationI just want to say you are the reason I’ve been able to loose 80 pounds of fat. And I am still on my journey another 30-40 pounds to go.

[@alincristianoprea9636]

We need more philosophy, more rants, more of this style of Dr. Mike. The main videos are amazing, but this is the cherry on the cake for me. +++The new set-up is so casual! Love it!

[@olevam1]

Agreed!

[@jeremyhelbing]

I very much agree!

[@coledriescher9401]

As much as I love fitness my love for intelligent individuals like Dr. Mike to discuss complex topics is a huge part of the reason why I subscribe to Renaissance Periodization!

[@user-yk8vj2bd9y]

Definitely more philosophy...Dr Mike you are straight up a genius

[@ogzachyg3979]

how you 5 hours ahead

[@OwlScowling]

Hot take: If we can help people without creating additional problems for them, then we should. I lost weight and got in shape the hard way. If someone else can't do it, I'd love for them to have an easier option.

[@williamhauser3686]

The world needs more people like you, Ryan.

[@qwertziop0]

Honestly, I was "blessed" with a very high appetite, I dieted down from 120kg down to 85, now after a couple bulks back up to 100-105 (currently lots of sickness and work stress so I'm not taking it as serious atm), probably a good 10kg of that is fat. While I was bulking I was eating very clean (95%+) and could actually rely on hunger to make me gain weight at .5 pound/week, that's how high my appetite is. While cutting I did 20 min cardio around my workouts, + one 2h cardio session per week (for endurance) and took a leisure walk 30-60 minutes every evening. Just to keep hunger at bay and increase my metabolic rate. This drug would be a blessing and a life saver for me, it would also enable me to work harder towards the part of the sport im passionate about (lifting for hypertrophy), I like endurance work but 20 min sets of liss cardio every day just to maintain gets tiring real quick and isn't fun to me

[@throbbinwoodofcoxley6830]

@@qwertziop0I’d just feel like I hit up up down down left right left right b a b a start on Contra…aka cheating. I’m doing it a second time the hard way, and I’d have it no other way.

[@roy7o9]

@@williamhauser3686yeah, more people that do it the HARD WAY

[@robertt9342]

Just pointing out, if people accept others taking drugs to gain muscle mass, something people do NOT NEED to do, then it shouldn’t be a big deal for people to to take drugs to lose weight, something many people NEED to do. To me it shouldn’t be a first resort.

[@brianmiljevich826]

I spent my entire 20's overweight, ultimately ending up at 525 pounds by the time I was 32. At that point, I started slowly figuring out how to manage my hunger and lose weight, now at 37 I am down to 320 pounds and still dropping. If I could go back and address my issues at 22 with medication and have an actual life instead of spending 6 years learning would I do it? Absolutely.

[@colinjensen]

The learning is the thing. Doctors don't seem to understand that I don't want to learn microbiology. Just tell me what to do, don't give me the tools to go find out myself. I know that doesn't work on some people, but it does for me. Why oh why in a room full of doctors and nutritionists do they always ask me to make the call (besides liability), why do they ask ME to go home and google medicines to decide which one I want? Ugh. I partially love RP because it simply says "eat these many carbs," not "pay attention to how you feel at 35g vs 30g and report back to us." Shut up, plug me into a tricorder and do your job, Doctor! Okay, ;)

[@75Veritas]

I was overweight in my mid 20's as well from Antidepressants. I got off them when I discovered exercise. Man, if only life had an instruction book but I try not to have regrets for things I can't change. Peace!

[@AngryOscillator]

@@75Veritas The irony of that is beautiful.... bro, that sucks

[@danielalexander8402]

As someone on Ozempic I’d like to throw in some anecdotes. 1) yes, eating healthier is important and I have always striven to that but after marriage and having to cook and feed people who refuse to eat healthy food that has been near impossible. I’ve spent a decade gaining weight and declining health in part due to dietary constraints placed on me by others. Having a doctor prescribe me Ozempic has helped this in two ways. The obvious way is that I can eat less and not feel hungry. That’s a huge win. Eating a small bowl of food twice a day and feeling full and happy is a great experience. The other way it has helped is that it served as a wake up call to other people that all my nutritional and medical citations I made about what we eat aren’t wrong because a doctor backed them up. 2) Having a narrow amount of food that I want to eat per day encourages me to eat nutritionally dense food and track my macros. Some of Dr Mike’s books have actually come in handy for that. So thank you. 3) I’ve always had a ravenous hunger that turns into crippling pain when I don’t eat above a certain volume of food. The doctors have never seen anything wrong with this, which has always seemed odd to me. Ozempic has neutralized this. I’m no longer in constant intestinal distress and I devote almost no time worrying about what and when I can eat next to soothe the pain. 4) I’ve always had severe social anxiety, which I think is attributable to hormones. Overnight after starting Ozempic that decreased and has decreased significantly over time. It’s a huge win and has helped me out significantly in my professional life and in the gym because I’m less afraid to ask for help and make contact with people. For the first several months I leaned on it as a crutch to just eat less. Over time the results were enough to help convince myself to push back more for eating healthier and to get others to chime in supporting me, which is something I’ve never managed on my own. That extends beyond family. Friends, co-workers, and acquaintances have all become more supportive of healthier eating habits and lifestyle choices because of the weight they’ve seen me drop. Whereas before they’d almost universally written me off or openly mocked me when I’d discuss why I was as obese as I was. Ozempic has been a new lease on life for me, but that’s my anecdote. I understand that many people will just use it as a quick fix. That’s their right. I hope they use it as a jumping off point for greater lifestyle changes.

[@RenaissancePeriodization]

Thank you for sharing your story! - Dr. Mike

[@Pdotta1]

Goof for you, take control of your life any ways you can.

[@elischrock5356]

I lost 80 pounds over the last two years, while my wife and kids ate cake, ice cream, chips, and restaurant food every day. I feel your pain, and I'm glad you found something that helps. I honestly wish I had done it with medication. I was miserable, and I made others miserable. I feel like I could convince more people in my life to "get healthier" if I didn't have to tell them in all honesty that dropping weight means being hungry ALL THE TIME... at least until you establish a new homeostasis. Wish you the best out there.

[@intersectedimplication]

I feel like a maniac,TLDR?

[@danielalexander8402]

@@intersectedimplication if you’re asking for a tldr The drug fixed several long term issues that I had while providing pathways for me to actually start eating healthy. There’s a lot more nuance to it but that’s what’s most important to know.

[@Rh92887]

I lost 100lbs on ozempic over 2 years. I'm currently at year 3 and have since hired a bodybuilding coach and have caught the bodybuilding bug. I learned how to eat, how to lift, how to meal prep, and how to count macros. I used my time on the drug to learn to change my habits and have been off the drug and totally fine and loving my bodybuilding lifestyle. Now that I know how to eat I'm never hungry but if I didn't have the help in the beginning I don't know if I would've learned what I know now. Thanks for this vid Dr. Mike.

[@merrieleiderman1885]

This is the way. It really bothers me that people are being told they need to stay on the drug forever to maintain a healthy body weight.

[@seansull]

Hell yeah! Proud of you👍

[@looli1327]

Thanks for sharing your story. This is how I’m using the drug now as a training wheels as I change my diet. Once I’m done losing the weight, my plan is to stop taking it and by that time I feel I’ll have all the habits locked in. I don’t think I would be this successful on my current fitness program without it. At least not without my mental health intact.

[@howardfairbanks6965]

I forget how wide Dr Mike's delts are with the usual lecture black background. The new set has obliterated my forgetfulness.

[@billyelliot4141]

He reminds me of a polly bull I had in 1986 😢. He used to get stuck in a gate. 🐄 🐮 miss u fred

[@kevinnistor1954]

​@@billyelliot4141rip Fred 🙏

[@rm06c]

Damn, this set looks like Dr Mike is bringing you in for an interrogation followed by some HIIT waterboarding.

[@giuliam2531]

😂😂😂

[@mrvee5395]

Future video

[@diversitydeliverer7094]

Mr Olympia Guantanamo bay

[@RenaissancePeriodization]

"HOW MANY SETS OF BACK DID YOU DO LAST WEEK?!" "Fuck, hit him again." - Dr. Mike

[@douglasauruss]

With an emphasis when they're pouring the water: "SLOW. SLOW." Get those eccentric gains.

[@MailmanMuscle]

About 2-3 years ago, my wife was prescribed Ozempic for the diabetes. The appetite suppression was unexpected, and turned out to be a godsend. In the past 2 years, she has lost 68 pounds. If there are any side effects, neither of us have noticed. That stuff works.

[@RenaissancePeriodization]

Holy crap that is amazing!! - Dr. Mike

[@StrokeofWellness]

Thanks Dr. Mike! Still on the journey ❤ (Mailman Muscle’s Wife)

[@joyhumble7768]

As someone with messed up hunger signaling, I appreciate the empathy displayed in this video. I spend loads of time every day hungry and wishing I could eat just to maintain my weight.

[@alexcorrigan3304]

It’s nice to see that mike has successfully mugged enough people to finally afford a background lamp

[@alatheus3443]

Thank you so much for the mature take Dr Mike. I work full time as a Data Scientist at a Hospital at the same time as studying for a Masters. I hit the gym 3 times a week, I swim the other 4 days a week. The ability to work hard isn't an issue for me. But I am overweight because my body is constantly craving food. Even when I'm eating healthily the amount of food it takes to feel satiated (and to be clear I mean satiated, not full and fully realize there is a difference) puts me in a calorie surplus. These drugs have been a gamechanger for me and it's nice to see a more mature, evidence based opinion.

[@kfreps5750]

So what are these drugs?

[@alatheus3443]

@@kfreps5750 well there are a variety and the video uses ozempic as an example and it's the most common one. Where I am in Australia there is actually an ozempic shortage due to a surge in use for appetite control so I'm using one called Metformin. But there are a few different drugs that have proven promising in this space so which one is right for your circumstances is probably a discussion to have with your doctor.

[@rickysmith6041]

I don't think there's a difference between full and satiated. Are you eating low calorie dense foods? Many healthy foods are high calorie dense like nuts and avocados.

[@rickysmith6041]

also, I thought you needed a master's to be a data scientist? I just got my bachelor's in math and physics and was trying to find a job, from my research a data analyst requires a bachelor's but a data scientist is very advanced and requires a master's. I suck at computers so I didn't get a job in anything I ended up going back to school as non matriculating.

[@AshBuddha]

@@rickysmith6041there is definitely a difference between the two. Being full makes you lethargic, being satiated means while you know you can eat more- you don’t need to.

[@v0idbit69]

You guys either have a really good comment moderator here, or you've somehow fostered a community in the fitness space that's not plagued with fat shaming and fat people hate. I'm going to go ahead and guess it's comment moderation. Great work, mods!

[@RavingKats]

It's so refreshing to read the comments on his videos. I fully second your comment!

[@mattwilson7443]

I think if you regularly digest Dr Mike’s videos your IQ is probably a tad bit higher than the standard internet dweller which in turn creates a healthier comment section

[@sirbrdfrd]

Great video Dr. Mike! I lost 75 pounds the "hard" way and still struggle to maintain because food is basically always on my mind. I use an app. to track daily calories/macros just to maintain because I know I can't just eat as I want as I basically always feel hungry. My wife is the exact opposite genetically. She does nothing to track what she eats and can maintain a healthy weight without any effort. Right now these drugs aren't approved for me because I no longer meet the obesity requirements, but hopefully someday they'll be made more available.

[@mcfarvo]

Same! 185cm tall 35yo man, formerly obese as high as ~124kg, now spent years "bulking and cutting" 79-99kg, always hungry, I eat 4 meals a day 95% of my year that are basically lean protein source + veggies + some fruit, e.g. Meal 1 egg whites + celery + tomatoes, Meal 2 fish/shrimp + spinach spring mix + pear, Meal 3 chicken + asparagus + cauliflower + broccoli + carrots, Meal 4 Greek yogurt + whey powder + berries. I am always hungry. I can eat 8-10 plates of food at a buffet where a normie would stop at 4 "feeling stuffed, thought of eating makes me sick." Only by God's will and long-suffering have I made it to the point where this week I shared a Twix candy bar with two other people and that was it (with black coffee, as my pre-workout) and it didn't lead to a hyperhagia episode; I could easily eat a Family/Party size bag of candy bars for Halloween or whatever and still hunger for more food. I have to be a monk when it comes to food and activity to simply be in a "normal" body mass range.

[@mcfarvo]

Oh, and my wife who has had our 2 kids and she doesn't lift or do cardio like me, she easily "intuitively" eats stuff like pizza, pasta, drinks beer, coffee with creamers, etc. She stays about 59kg.

[@panchita0476]

Former obese child here. It's actually nice to see I'm not the only one who struggles with hunger. No matter how healthy I eat, I know I'm eventually gonna get to a point where I can't resist the need to eat big amounts of food. I constantly have to be aware of the quality and quantity I eat. It would be nice to feel normal around food, I hope those drugs will be more available on the future...

[@elischrock5356]

same

[@boshirahmed]

​@@mcfarvo they did research, people with high metabolism, under 24 hour CCTV were found to constantly move their bodies, they do boring things like walking or sleeping with constant small movements that's why they burn more calories. Think of how much a baby moves and how much a senior citizen moves.

[@Kane6676]

I love that you say someone’s hunger is genetic! Almost never see people who are in shape talk about this. My brain is constantly telling me to eat eat and then eat some more. It’s a non stop fucking battle

[@kevinandres346]

I like your analogy of the “problem pile.” I think the myth of “getting rid of problems makes you a pussy” is spread by grumpy old people. Like the ones who say “they walked uphill both ways to school.”

[@praguevara]

Great video. I'm at 32 BMI and been dieting and taking semaglutide 0.25 for 3 weeks, and even though it's not supposed to be a clinically effective dose, I can tell it's made dieting much easier. I no longer have serious hunger, and sometimes even struggle to eat 2000 calories. I'm even afraid of upping the dose since it's so effective lol. This really makes me feel like obesity will be a solved problem when more people got on it.

[@charlies8282]

On it’s own it’s super powerful agreed. I think if then people can combine it with lifestyle modifications it will be rocket fuel to change their health. Glad to see you had a good experience to add to the overall anecdotal data and experience

[@Yupppi]

Good luck and hopefully you get to enjoy your goals!

[@Marc-ip4ii]

A higher dose may cause more nausea. I find as they increased my dosages it got really interesting. Still struggle to lose weight even do I’m not hungry 80% of the time. Keep at it for f it works for you

[@praguevara]

Thanks guys!

[@arihaviv8510]

But you know what they say, there's always room for dessert. Billions of dollars is invested in developing and marketing food that people will want to eat even if they are no longer hungry.

[@gamblestyle7337]

If the media and pharm companies would present and market these drugs this way, they would not get nearly as much pushback. As always the croc master Dr. Mike beings us the real fair and balanced perspective. Much love Doc!!💪🏻

[@Conformist55]

This is probably the most well rounded take on these drugs I’ve seen yet.

[@nikola3058]

Dude, 30% of my mental power is spent on supressing the urge to eat. If I could keep my current form (roughly 13% bf) by taking a pill, give me that stuff right now. More pretty girls around, everyone is looking good and lean like it was intended, I'm all for it.

[@Klake-bk2dp]

Something that is not mentioned either is the monetary and environmental benefits this drugs has.

[@Bertziethegreat]

I'm all for it. I started with weight lifting. When I reached my weightlifting goals, it spurred me into trying weight loss. When I hit my weight loss goal, it spurred me into doing cardio. What will happen when I reach my cardio goals? No idea, but I bet it'll be interesting.

[@PornEqualsHappiness]

If you find the same path as me once you're done with cardio goals you'll stick with fitness for the mental benefits but you'll find a new passion unrelated to physical fitness. Good luck either way!

[@benkse2010]

I agree with you 100% on the feeling of being "empowered". I didn't know or believe I could ever be in good shape, I was at a minimum chubby my whole life and at my worst clinically obese (36%) body fat. It wasn't until I grinded and dropped over 50 pounds while lifting to try and build/keep some muscle that I really felt, wow man you CAN do this. I still am not anything to look at, but from where I came? Its night and day, seeing myself at low 20% BF now is all the motivation I need to keep going. Its built into me now, I know I can do it, I just want to keep improving. The pill could have had this same effect on me, or can on someone else.

[@StuntMug]

As always your perspectives are so much more measured and deeper than almost anyone else, it's greately appreciated.

[@jimhollywood2763]

Ozempic has helped me greatly. This was started due to my diabetes. I still eat healthy but this has helped me drop weight which is important. Ozempic is not a replacement for eating properly and exercising. It is in addition to. Your point is correct with me. I am more encouraged to eat better and lift more because I get a better bang for the effort. I am down to 240 from 280. I need to get under 200. This is helping. You nailed this.

[@briansteagall350]

I like your rants and takes and such, not only because you are highly educated and experienced so you provide good insight, but you are also just genuinely funny and entertaining to listen to. I'm excited to see what you are considering that has you asking this question!

[@oklibrarian]

I'm watching this video (and all of RP's videos) because I want to gain more lean muscle mass so I can live a healthier and more active life. I want to gain more lean Muscle Mass because I recently lost 100 pounds and am no longer obese for the first time since college. I recently lost 100 pounds because I had gastric sleeve surgery. I had gastric sleeve surgery because for some reason the same willpower that got me a PhD, a great career in leadership, and many other huge life achievements wasn't enough to allow me to ignore my hunger. The surgery didn't solve all my problems, and it sure as hell wasn't the easy way out (nor is Ozempic). What the surgery did is reduce both my stomach capacity and my hunger hormones enough to give me the ability and bandwidth to take on a higher class of health problem than simply white-knuckling my steering wheel as I drove past Wendy's on the way home. Problems like whether I can eventually squat my body weight one of these fine days. :-)

[@RenaissancePeriodization]

Thank you for sharing! - Dr. Mike

[@oklibrarian]

@@RenaissancePeriodization And thank you for your unique combination of dark humor and data-driven fitness advice! Your maintenance video from the fat loss series was very useful for me when I hit goal and was at a bit of a loss for next steps.

[@kimdecker8901]

I welcome more rants! They're factually informed and both cogently and convincingly presented--which is to say, they're valuable. I thank you, Dr. Mike!

[@MrMetaMeme]

I’ve been binge watching RP for a couple weeks now and I genuinely appreciated how compassionate Dr Mike is around people who want to lose weight. I started on Ozempic and I’m now on trizeptide, it’s helped me lose 30 kilos and improve other aspects of my life. The food hunger which felt like such a fucking shackle for my whole life is now so manageable that everything is better, healthy food tastes better, going to the gym is more rewarding, life in general is just easier being on the medication. Thank you Dr Mike and Scott the Video guy

[@gbpBrett]

I very much enjoy the way you portray every topic I have heard you speak on. You develop arguments and counter-arguments in a very easy to follow manner while still interjecting comedic relief. If you would have been my teacher/professor for every class in my life, I would have had no fear in going for a doctorate.

[@joshhaddock88]

This is a really encouraging take. I really struggle with cravings whenever I'm on a fat loss phase, it makes it unbearable and I've never been able to keep the weight off. Been looking into these drugs lately and wanted Dr. Mike's take, and his thorough and empathetic position really helped ease my mind.

[@donnaryan71]

I'm convinced type of food has a lot to do with hunger signalling. Years ago I was a live-in Nanny to 3 kids. For 5 days a week I was responsible for their breakfast, lunch and dinner. On the weekends, their (junk-food addicted) Dad took over. I fed the kids mainly home made meals from scratch, nothing fancy but food mostly in its natural form. For lunches I made them wholegrain sandwiches to take to school; protein, some salad veggies, some fruit, and nuts and dried fruit or cheese for snacks. They always came home with energy. On the days their Dad fed them - mostly Maccers for lunch, they were coming to me an hour after lunch complaining of hunger, asking for a sandwich or a banana. I knew what they had eaten was double, two and a half times the calories of the lunches I made them, but they were hungry anyway. Unfortunately I was not allowed to feed them because I was 'off' on weekends (and it was heart-breaking) but their hunger after fast food was apparent, compared to the more natural, higher fibre, lower sugar food I fed them. This highlighted for me how a lot of junk food simply isn't satisfying long enough, and hunger kicks in too soon. So of course, people buy more because they're still hungry.

[@awsomeshadowdude11]

Dr Mike you are just a godsend in this world of misinformation, poor education, dry humor, and gym bro science. You one by one body slam, choke hold and RKO all these issues and tackle things I feel I’ve heard all my life and you’ve done it with verifiable data that has improved my fitness journey not only physically but mentally and I really just wish that more people could find you. Everyone needs a Dr Mike in their life, thank you for everything

[@CalebAAvery]

Great setup, definitely not the old layout with the background, but I like this more. Definitely ramble on more with whatever else you'd like to talk about, as well.

[@Exercise4CheatMeals]

Thank you for making this. So many people are thinking 1 step ahead instead of thinking 5 steps ahead. Mike summed it up pretty much perfectly.

[@ShovelChef]

I don't know if you anticipated how applicable this lecture would be to areas outside of fitness, but it totally is, even when you were just talking about the drugs. I didn't even see the last 3rd coming, but keep em coming! 💪😄👍

[@factualgiblet]

Anecdotally, modafinil is great for appetite suppression, but tolerance does build over a few months and can disrupt sleep significantly. It didn't work well for me.

[@Seeves1982]

I know this is a year old video, but you asked if we’d like more content. Yes I would. I’ve been binge watching your videos for over two months now. I found you through researching TRT. Which I’ve decided to do after weighing your options of if it’s worth it or not. Labs came back at under 250 and I was starting to notice cognitive and emotional changes. Starting TRT has reinvigorated me to get back into the gym.. Watching your videos has shown me a lot of the mistakes I made when I was younger. This week I’m going to get the RP diet app. I’ve always “attempted” to take care of myself best I could, but never researched any details. I was convinced to do the KETO diet, which I was able to stick with for almost two years and decreased my weight from 305 down to 230. I felt myself starting to rebound and couldn’t get back into KETO because (honestly after awhile it just sucks.) As a staple it suited me well, but when carb cravings it was two easy to hit a snickers bar instead of some fruit because I had deprived myself for so long. As part of making my 40s and beyond the best part of my life I wanted to find a responsible way to have a balanced diet and I’m convinced that periodization is the right way. I’m following the steps you’ve outlined. Scheduling my meals and eating Whole Foods consistently for two weeks which has gotten me down to 240, but keto not being a calorie restricted diet (mentally). I’m not sure I could have combated the hunger cravings without the help of semaglutide. So I really appreciate this video in particular. I never struggled with willpower the junk food thing only came after keto. My carb of choice has always been rice and mashed potatoes. But mentally I’ve always over eaten and struggle to feel satiated. Ozempic for me is a crutch to not get discouraged while I’m learning new skills in diet and reinvigorating my enthusiasm for the gym. Honestly I’m all in on the RP culture if that is a thing. I found FitBod before I found RP and already paid for the year, but as soon as that’s up I plan on switching to the hypertrophy app and am currently applying the principles for periodization into the workouts provided by that app. With the information your company gives out for free it’s honestly made FitBod obsolete. At this point it’s mostly just inspiration for tricking myself into progressive overload when my mind says I’m not ready yet. Please continue with the great content.

[@selfsacrafice]

I just subbed and I'm binge watching. I started my weightloss journey in 2014? I think. I was 325 -330 and struggled horribly with appetite. I would go from under eating to over eating for years trying to figure it out. I'm 250 ..... yeah. Still working through appetite issues but I think I'm finally getting the hang of it. I failed so many times I kinda wish this existed back in 2014. Anyways love your videos. Learning some new information and hopefully buy the end of this year I'll be 220 which was my goal back in 2014.

[@wowandrss]

A weekly or biweekly rant/philosophy/getting to know Dr. Mike would be absolutely... lovely. Thanks for all you do.

[@deegreen4692]

Love hearing your perspectives on aspects of life as you seem to make pretty reasonable and rational takes on most things imo…. Much respect Dr. Mike 🤘🏽

[@anthonyedwards6409]

As someone who has been on Mounjaro for 5 months and just watched this video, Mike is 100% on the money as usual. For me once the food noise disappeared I found myself more drawn to healthier well balanced meals. Am not saying I eat healthier all the time but there is definitely something about lack of food urges and junk food and it is a game changer. I’ve lost 1-2 pounds per week on average, nothing crazy but am now 3 stone down and into a normal bmi range. As Mike suggests am now closing on looking what the next step is, again completely on the money about the increased desire to increase activity and build muscle. If Mike does read this comment, please please can you do a video on his view on next steps as there is a lack of good advice. For me I know I have lost some muscle mass, I know I’ll likely rebound if I come off completely, ideally I want to reduce to a maintenance dose which encompasses a starting foundation of muscle gain without further weight loss. Any advice would be amazing.

[@davidking7858]

I always listen to Dr. Mike as his intelligence and attention to detail is off the charts!! Thanks again brother this is great info

[@JasperDD]

I recently discovered this channel, I basically signed up for lectures, comedy, and actual enlightenment. Ty!

[@seborbie]

Love the new set, looks amazing and makes Dr Mike look even more jacked that he already is.

[@JaihindhReddy]

This is my 2nd favorite video on this channel, second only to the one where Dr Mike explained the 6 constructs of adherence ("Getting motivated to lose fat through dieting"). Also, yes. Ranting about life, philosophy and other stuff would be highly appreciated.

[@johnfvick]

Yes, more philosophy, more rants. Everything you put out is high quality.

[@Kamemom]

This is by far the best explanation I've heard of what GLP1 drugs are, and how they can be beneficial. Thank you! I've been on the fence about starting them, after spending a decade steadily gaining weight despite every conventional intervention. This is exactly what I needed to hear.

[@Mzamojali963]

I'm interested in your rants Mike, great video as always

[@hellzbellz272]

I Sped here when I saw Dr Mike has done an opinion piece on the new weightloss drugs. As a layperson in the fitness industry, but with a background in science, I find it particularly daunting just how little scientific material on weightloss and excercise is readily available to laypeople. Its either people who may have some training in fitness but not enough in my opinion for me to feel comfortable trusting their data or thesis, or just straight up misinformation. This was honestly the biggest struggle for me to first start loosing weight and exercising. I will admit, I have been on the fence with my opinion about weightloss drugs, not thar they are applicable to me, but I just hadnt gathered enough informed information to form an opinion yet. I really love these videos and generally hearing an actual proffessor discuss peer reviewed studies and research present his findings and am so glad I stumbled upon you. Please do more videos like this!

[@ibrahimtastekin275]

Why would people be upset about obese people finally having an easier time getting healthy? These people deserve what it feels like to be at a normal weight and happy with their body. Making it easier to improve other people's quality of life is one of the best things sciencs can do.

[@cavaIorn]

I don't always comment on your videos but I watch them all. This was one of my absolute favorites since you cover what I always thought about progress and life. There's always the next problem to solve.

[@shaneallen1192]

I started out in the “ Just use willpower camp.” By the end of the video you brought me around to your way of thinking. If it can help people stay at a healthier weight, that’s a good thing. I’ve seen so many folks at the gym that are overweight and give up. They work soooo hard and don’t see results. I can’t imagine how disheartening that must be.

[@julianzacconievas]

Bro. The value in listening to this. Dr Mike, you magnificent beast.

[@WaknUpDed]

I love the rants!

[@user-ps4ky5jk8w]

I used rp and my coach through them since 2015 when I got diagnosed with hashimotos it has felt almost impossible to get a pound off due to inflammation. I’m now on tirzepatide and using my coaches templates and weight is moving easily and my body inflammation is almost gone. Autoimmune stinks but RP rocks !

[@Mapople1]

The argument on "if we had robots do our chores for us, we could could focus our time on higher value add activites" hit home. Heard a story from my girlfriends dad. They asked his grandmother who was born in like 1890 or something what the greatest technological advancement she lived through was. They thought maybe electricity, or improved plumbing or cars etc. Without skipping a beat "indoor heat" was her #1. It immediately solved the heating problem. Prior to this a ton of time in the day was spent collecting wood/fuel, splitting/preparing fuel and stoking the furnace. That ~2-3 hours a day was just given back to everyone and now its completely taken for granted.

[@cysecgnz]

I really don't want to because I feel like a failure, but I feel this is something that would help me a lot. I am definitely working on getting my nutrition together; I'm finding healthy recipes that I can meal prep and going to be using the RP Diet App. That said, I still get really hungry and when I do, I'm going to grab what is easiest to grab and quickly eat, which is junk food. I also tend to binge when I get hungry. It's not an ideal situation, but I do feel like it could be a game-changer for me.

[@mitochondriac5946]

No matter how much you dress it up, there’s always a trade off.

[@kylepagel9360]

I love how people with genetic advantages talk down to people who consider using drugs to close the gap. They have no idea how much easier they have it. Thanks Dr. Mike for being a rational and compassionate voice, the two are not mutually exclusive

[@VelosportTaylor]

My dad has struggled with disordered eating for as long as I’ve been alive. The last few years he’s tried really hard to eat in what he believes is the healthiest way possible for his goals. A few months ago, he started taking senaglutide. I have watched as he has lost all hunger, lost the little bit of muscle he has had, and gain fat because he only eats garbage because “nothing tastes good” when he’s not hungry.

[@RenaissancePeriodization]

I'm really sorry about that. I think it's probably wise to discuss dosage reduction with his doctor, as well as getting him to commit to healthier eating. - Dr. Mike

[@deborahanderson7510]

Rant more! You are NOT stupid, you are highly intelligent and hugely entertaining. Any subject, always more on nutrition tho, all day long!

[@charles3727]

A couple of counterpoints I’m not sure you answered that I’ve heard from some other fitness types are: 1. The side effects are non-negligible for some people, so they’ll feel awful whilst losing weight 2. Once they stop taking it then the hunger returns, so they have to take it forever (and then see point 1 above) Any thoughts on these?

[@pablov1323]

Yes. I heard too of nasty side effects mainly nauseas

[@Ryan_DeWitt]

@@pablov1323 That is how the drug reduces appetite, or most of how it does it. Nausea, even if mild is a great appetite killer.

[@pablov1323]

​@@Ryan_DeWitt yeah, that is the point. Obese people will still have to choose between managing high hunger levels or dealing with continuous nausea...not sure what will be worst in the long term... you will eventually be sick of feeling like crap and abandon the medication

[@RenaissancePeriodization]

1.) Yep, but most of those are due to too high a dose or poor eating habits carried over from before the drug. 2.) Yes, probably. I'd view these drugs similarly to blood pressure drugs: chronic intake. - Dr. Mike

[@charles3727]

@@RenaissancePeriodization Dr Mike, cheers for the response - gives a lot to think about. Ps keep up the rants

[@donaldwindland]

I am first hand proof that you can do it both ways. Trizepitide is wonderful and killed the insulin resistance that made it so hard to loose weight the first time I did it. Thank you for your reasonable response and not loosing sight that it is a stepping stone to something else better.

[@danielkanewske8473]

Genetic boost? Yes, please!

[@ringokid12]

Hey Dr Mike :) I have become a loyal subscriber of your channel for about 4 months. I have really enjoyed it and learned so much! thank you!! I have worked out since university (with my on and offs, usually summers off, where I bike and golf, and walk more). I have always struggled with keeping the weight down. It is a huge battle for me and I do believe it is largely my genetics. Lots of people assume I am stuffing three cheeseburgers down my gullet when they are not looking but the simply isn't the case. I would hardly eat anything all day, and I may body would still hang on to fat. I think my body thought it was starving. So after trying everything else I thought Would try your more scientific approach and started your 12 week fat loss plan three months ago and I lost 24 lbs in 12 weeks. that's 2 lbs a week, which I am super stoked about. I have plateaued here at this weight for a month now but I was also kinda taking a break from being as strict as I was the previous three months. I am now on Ozempic and Metformin and I hope they can help me lose another 24 lbs! but I am a little worried it will not work for me, and here is why. It is related to the comments you made regarding watching skinny people eat. I have often noticed that the thin guys, who are sometimes muscular as well (but not always muscular), eat like gorillas and lions and will not gain weight (fat). They will have three huge plate fulls and one dinner, to my one (and they will have desert and I will not). And to add to the torture, they will be a healthy 170-190 lbs (5'11-6-2'2) and I am 260 at 6'3. Our activity levels are also the same, and mine are actually probably higher. This has always seemed to be unfair to me... So I don't think that skinny people just eat less. That may be the case with women, but definitely not with the men I have been around. there is something different going on in their metabolism and genetics. I would say my will power is far greater than theirs too, as I also eat healthier food. I wonder if you could surmise a reason to this?

[@jacobhaley5387]

I've been on semaglutide since the end of November and have lost 22 lbs. I completely agree with all the points in this video.

[@ontcaperchic]

Did you have side effects?

[@jacobhaley5387]

Mild waves of nausea and constipation when I went from .25mg per week to .5mg per week. Not enough to dissuade me from it.

[@kylerichard1285]

The bandwidth point is so critical. Im taking semiglutide as i write this. Hunger is like a yawn. You can fight it, and you can win that fight... For a time... But the war is another matter. Calorie dense food calls to me. It is a distraction. Fighting that leaves less patience and bandwidth to do other healthy things. I have the patience to cook now without snacking while i do that. It helps. It really does.

[@aaronjosephs2560]

I think this is a GREAT video, but I also think you significantly underplayed the side effects of these drugs. They are incredibly powerful and useful, but they certainly do have serious side effects for many people.

[@RenaissancePeriodization]

Almost all of the side effects are from people taking too high of doses or from still trying to eat the same way as they did before the drug, I think? - Dr. Mike

[@aaronjosephs2560]

@@RenaissancePeriodization maybe this is true for ppl taking it exclusively for appetite control, but it does other things--i know someone taking it because their cortisol system is very disregulated, and it has been immensely beneficial but also has had serious side effects (that are worth it, but I certainly wouldn't want)

[@chrisbrookerd]

I couldn't agree more with your take on Semiglutide. I have been taking it for about 8 months and have gone from 283 to currently 218. I have recently decided to take my transformation to the next level and finally go after visible abs for the first time. This interest is what made me find your channel.

[@pitviper346]

I’ve been a healthy eater (for the most part) and exerciser for 20 years. I am RIGHT on the edge of a healthy and ‘overweight’ BMI and I’m more concerned about weight than I’ve ever been . At 55 (& going through those woman hormone changes 😒) it’s such a struggle just to maintain, let alone lose weight. I tried a semiglutide for 2 months and lost 10 lbs., but also lost muscle and energy. I loved that I didn’t obsess about food, wasn’t hungry and didn’t eat as much, but damn, I was SOOO fatigued all of the time and the lack of energy stressed me out even more because I had terrible work outs or didn’t exercise at all. Sure, the drug is working, but you don’t get the (mental or physical) benefit of real exercise. Anyone who’s been exercising for a long time knows how you’re affected mentally when you DON’T exercise. The drug is like a mental MINDFU#K. As with anything that modifies your body using medical assistance, you sacrifice SOMEthing 😢. I wish I had a Dr. Mike in my life to guide me on where to go next!

[@nrgmom77]

I have been struggling for months w overeating even when I’m 80/20 or better healthy/unhealthy - pretty much 95/5 if you count protein shakes as healthy haha - and just signed up for compounded semaglutide through my doctor. I watched this fresh on the heels of Dr. Lustig’s nearly 180-degrees-of-difference take.. I respect Dr. Lustig highly but I think I’ll take this super jacked bodybuilder’s positive and awe-affirming take, because yes this is pretty much a goddang miracle. Also, he made me whoop with laughter a couple times and yes, love the sociopolitical commentary sir :) …want to add that if these drugs had been around even 10 years ago maybe my mom could have been a grandma to my four kids. She passed away in 2015 from complications of overeating for decades.

[@rthiago1]

Dr. Mike, you make me see hope in humanity. Thanks.

[@MartinTreurnicht]

As someone who has lost 50lbs in the past 2 years, it's hard work but the hardest for me by far was fighting the hunger cravings when on a weight loss phase, and i would consider myself someone with a lot of willpower. This would be something that even i could have benefited from. I think this is great

[@mitchdermer4359]

If you put out a regular podcast with you ranting I would 100% be in. I would also love a video on how to water cut for fights safely and effectively - I do bjj with same-day weigh-ins typically - water load? Salt load? Glycogen? Should I stop taking creatine? Please help, I can’t win fights at my natural weight and might lose less badly if I can go down a division.

[@Maxaldojo]

Thanks for this Dr. Mike. I came to you and RP through Adam Ragusea. Adam and other Internet chefs have helped me improve my cooking skills to make healthier food choices. I've gone through the weight management mill for most of my life. I crushed my BMI from 45 to 35 to qualify for hip surgery and ballooned back up when my right foot collapsed. I learned how to wrap my foot with athletic tape to allow me to walk (which is part of my job as a land steward for a land trust in Ohio). I needed something to help with my appetite and Ozempic is helping. Reduced hunger, reduced portions, and weight loss. Not to say there haven't been uncomfortable side effects, cuz there have been, but in general manageable. I appreciate your discussion on the topic and will continue along this weight management journey.

[@MaskedManMikeMD]

I was prescribed Saxenda in an effort to get leaner with my diet and exercise regimen. My issue hasn't been so much unhealthy choices in meals, but unhealthy choices in SNACKS. And so far it works REALLY well getting rid of the snack cravings. As long as breakfast lunch and dinner choices are healthy, then I see this as a GREAT option to help with fat loss, especially if the meals consist of good protein.

[@minimalsheep8900]

I thought this was really beautiful. I have really always despised the mentality "we have it so easy nowadays". That's not a bad thing! As old problems are solved, new and unforseen ones arise. We will never run out of things to solve. Now I have a more concrete basis from which to argue that point. I really respect you and what you do and the way that you think about things. Sincerely thank you. And I would love to see similar things like this.

[@MadBenStyke]

l love a good Dr. Mike Rant, would definitely listen to more. also if you don't already have any videos out on basic gym/fitness terms and etiquette (myo reps, meso cycle, don't curl in the squat rack etc.) would love to see that for beginners such as myself.

[@douglasauruss]

Stellar breakdown and perfect conclusions. Mike Israetel is a truth-seeker and a pragmatic gentleman and scholar. As evidenced by being a libertarian, a fan of Steven Pinker, behavior genetics, understanding the ethical arguments for eating less meat, and using calorie density to eat well. And to top it off you don't like poodles. Yes. Yes.

[@juanpablogonzalezobando8678]

You second all my feelings and toughts, like an obese person like me, people dont understand the depression, blames and feelings behind this massive body. Thanks for sharing this

[@colemansmith4704]

I like the rants, interesting perspectives

[@thebluedogILU]

What Dr. Mike said at 12:38 & 12:29 is EXACTLY what happened to me. Sure this is anecdotal evidence to support the hypothesis, and I didn't start taking a weight loss drug per-say (more switched to a medication that allowed me to feel my hunger cues again rather than just being bottomless) but after about a year, lowering my portions and losing 30lbs, I suddenly had this flash: like holy shit wait a second I can totally start working out and genuinely, eventually, become lean. So I did! And working out made me want to eat healthier foods so the whole thing snowballed to creating a healthier, happier lifestyle. One thing allowed for me to feel motivated and empowered to make the changes I needed. Without that first step I don't think I'd be where I am today.

[@rikmcrae]

Yes, more philosophical commentary please. We have Philosophical Friday at work, where everyone has some comment or question for discussion like “Your stomach thinks that all potatoes are mashed.” Or “If cats had wings they’d probably still just fucking lay there.” Great fun and occasionally educational.

[@ToraJutsu01]

I would love to see more videos “arguing to convince” style on different topics linked to sports science, future tech, philosophy & economics. You do such a good job of steel manning opposing arguments and picking them apart that often times you will articulate things I’ve felt for years but could never quite put into words. Makes us all better thinkers.

[@floriancazacu4504]

My only criticism if that hunger isn't the only reason people eat, they also eat because of anxiety and stress and stuff. Which is, I would hypothesize, the main reason people overeat, not because they're hungry after eating 3000 calories that day. But maybe less hunger sort of helps with that too, in that it makes it clearer for people it's not the hunger that's making them eat cause we just squashed that, and they're still eating too much so they are more likely to go "oh ok, there may be something else here" and spend some energy getting help for that. Other than that the fact we can now fix the hunger part is amazing.

[@institches2750]

Great points, and I hope we see them become reality in the future. Some points I have noticed within my own family: 1) The Ozempic craze has reached a point that there's a shortage impacting those with diabetes, which is what the drug was designed and marketed to treat. 2) Family members are sharing it among themselves without a prescription or medical guidance. Is that safe? No idea! 3) Family members are...fudging the truth to their doctors hoping to get it prescribed, or to get their insurances to approve it. 4) Apparently it can cause nausea. 5) Anecdotally, the efficacy seems to depend on the injection site. Arm vs stomach, for example. Hopefully, that kind of thing will work itself out as production ramps up and it becomes more accepted. But I'm a little uneasy watching it unfold in the short-term.

[@gifridge]

I've struggled my entire life with my weight, and there isn't a time when food is not on my mind. I've had lots of ups and downs and yo-yo dieted, but I've never considered taking medication. I always thought that I can lose weight through sheer determination and will power. However, this video has really enlightened me made me curious about these alternative avenues to becoming healthier. Dude, I love your side stories, comments, and general overall sense of humor. I can't tell you how many times I've laughed out loud during your lectures. Keep it up. I say more philosophy is great, but please stay away from politics. It's such divisive topic as it is. Can't we just let health and fitness be the one guiding topic that unites all of us who watch and subscribe to your channel?

[@lowlyloop]

Loved your take on all of this Dr. Mike. I also get super excited when thinking about all the progress and advances we have been able to make on all fronts of technology and pharmacology. I think one trap even well-meaning people can fall into is conflating the idea that "overcoming adversity is good for you" with "all adversity is good". But sometimes, there really is just needless suffering, and the more of those problems we can solve, the better! I'm excited to continue to work towards paradise!

[@stevedoidge-harrison2337]

I've been fitness for over 30 years and I've learned more from Dr. Mike than any degree or course! An amazing fountain of knowledge, a great communicator, and, no joke, the funniest guy on the internet! Regarding these drugs, is there not a potential issue, if the patients are not active, that there will be a drastic loss in muscle as well as fat?

[@tideofmayo3880]

What an amazing video and amazing perspective. So respectful, thoughtful, well delivered, and down to earth way to look at this situation. If only more people could be so wonderfully adapted to working with and accepting, and redelivering information in ways like this. Absolutely amazing.

[@jessicamatthews8141]

I am a frontline primary care clinician in south Mississippi. I would love to hear some commentary on the phenomenon of weight GAIN on max dose semaglutide or tirzepatide. I regularly prescribe these for DM II. The only thing I can imagine is that patients are so confident in the quality weight loss potential of the medication their behaviors significantly worsen or they are eating more calorie dense foods. This is the same phenomenon seen with patients who fail to lose weight after bariatric surgery. I also think a lot of binge eating behaviors go unnoticed. I agree with everything you said in this video. The other issue we face in the south right now is actual supply of GLP-1/GIP RA even though insurance coverage is expanding.

[@myatkhineoo95]

Love this Mike. I couldn't agree more. I was obese in my early 20s and cravings were the toughest to get over. Thankfully, the doctor recommended a hunger suppressant and dialled me in. Lost weight so fast, got me into the gym and everything. Once off, I did bounce back but not much, since I enjoyed the energy from low weight and just going to gym by then.

[@samiqoo1711]

I’ve been overweight since I was very little, and I would always feel hungry even when full. Always had cravings for sweets and unhealthy foods. Didn’t matter what I was eating, and I would do my best to eat healthy but especially as an adult I found that the pain of hunger would stop me from making healthier food that by nature needs more preparation than something prepackaged. Taking semaglutide not only has helped me with portion control, but I don’t feel pain from being hungry and have more energy that I’ve put into making healthier food as well as getting regular exercise. Almost 3 months in I’ve lost almost 20 lbs and I still have energy and feel great.

[@shmuckling]

I would absolutely love to hear you talk about life, philosophy, global politics and other topics not related to fitness.

[@Luke-ef9ft]

Would really like to see you rant more Dr Mike!

[@SajaStoica]

I come to your channel for the expert opinions you offer. I feel like there are plenty of places to get political rants, but less places to get the kind of reliable information you provide.

[@bernhardotto9201]

Thank you so much. I found your speech realy encouraging.

[@asdfasdfasdfasdeff]

Absolute game changer for me, and if you're able to switch from Semaglutide to Tirzepatide then it's even better. I don't give a shit what people think, some will offer their opinions (usually online when they're hiding behind a mask) but in the end do what is right for you. I've never felt better. Everyones bodies are different just like in the body building domain.

[@Yolandow]

I really have appreciated your channel and the info you share. I have to say that I have been dismissive of this new drug and the desire to “take the easy way out”, HOWEVER the way you shared your view point was very informative and it’s actually helped me to see a better way to look at this and it feels more compassionate. Thank you for your approach. Please keep sharing.

[@SuperNiels91]

Always want to hear more of you Dr Mike, on any subject!