Thank you for sharing this webinar! I'm stage 3b T3N2 (4 lymph nodes), and my Signatera came back negative post-surgery. I know ctDNA is guiding ACT treatment decisions for Stage 2/low-risk 3 ; but for us in the high-risk stage 3 category, what prognostic impact does a negative Signatera really have? For me, it gave me the confidence to do only 3 months of CAPOX and continue the Capecitabine for the full 6 months. I'm on my fourth month right now, and anxiously awaiting my next Signatera result. I guess what I'm asking is: does the confidence in a negative Signatera post-surgery hold any weight for the high-risk stage 3 patients like myself? Thank you for your time!🙏