Sliding Filament Theory Of Muscle Contraction Explained

Sliding filament theory explains how muscles contract at a cellular level. Learn more and test yourself with our quizzes here:
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[@sairajacob4535]

2hr lecture in 2minutes! Thank you💞

[@W_Incognito]

How did it go ?

[@asmookypooky]

@@W_Incognito lmfaoooo

[@swap_agrawal]

That's call crystal clear explanation 🔥🔥

[@paramanandbalara3602]

Keep in mind that acetylcholine do not enter in the sarcomere , it remains at neuromuscular junction or motor end plate. SOURCE - NCERT

[@swap_agrawal]

@@paramanandbalara3602 Thanks man for your information 😊... I've passed out but I'll keep it in mind for my current first year physiology lectures on NMJ and during tricky exams

[@MESSI-IS-THE-GOAT610]

​@@paramanandbalara3602Yes

[@kushagraverma3697]

​@@paramanandbalara3602 Ca++ karta hai sarcoplasmic reticulum me

[@FIFANATICS]

So much info condensed in a digestible formulation! Thanks

[@ijazaliijazali6510]

Explained very well thank you very much now my concepts are clear

[@r2fteachpe]

Glad it helped

[@trevandrea8909]

Thank you for this video Very, very helpful I literally watched this video to prep for the upcoming Biology test tomorrow...

[@langrisvaude9298]

Same...

[@hayamalik5716]

Same here

[@anonymousxd6310]

@@langrisvaude9298 Hiiii jungkook 😁 How are you?

[@razok2125]

Mine is in 45 minutes :)

[@rankitabhuyan7079]

Just helped me out for my exam . Amazing explanation 👍

[@pepitobenegas]

So easy and well explained

[@trevandrea8909]

I know right

[@kylelewis-sinclair278]

Shes really not Trynna catch her breath going hella fast🤦🏽‍♂️

[@alyciaani]

Slow the video down

[@factualminds_tamil6572]

you can change playback speed

[@underherdomain1361]

I'm viewing with 0.75x

[@Mr3dTube]

Extremely well explained and illustrated. Is there a complementary video for eccentric contraction?

[@abigailadebambi3750]

Very helpful... My assignment is done🙏

[@WaytoDeen561]

Toughest concept made easy 😊 thank you 😇

[@abdullahrashid2314]

I swear by god this thing helped me more than anything else.

[@kellyfrances9435]

Actin is basically crowd-surfing on myosin. Thank you for explaining! I could not understand my professor's lecture at all.

[@ebrelus7687]

Brilliant. Nature is brilliant. Wiser than whole humanity combined will ever be.

[@hoperoy]

Thank you very much to make a video on this vary topic..It was indeed very helpful ❤️

[@creativeniqabi4847]

Really really helpful. Clear cut visualization. Thanks alot. Stay blesséd💕

[@mahathidamam806]

Veryy clearly explained..good✌️

[@MEmaanAlam]

R u a medical student?

[@jjlatinopedia]

This 2 minute video was a 3.5 hour lecture in the Army's ICU course.

[@miraculer4.012]

Nice explanation but little bit it is fast . Please slow your speed of explanation. Otherwise it is the best one ✅

[@LD67117]

How does the myosin head pull the actin inwards? Is there some conformational change in a protein leading to shortening or something?

[@hydrothermalworm7778]

The myosin motor domain is what's doing the ATP hydrolysis. Myosin with no ATP bound is locked to the actin filament. ATP binds the myosin head, causes conformational change in both the head and lever arm, releasing the head from the filament and swinging it forward. ATP is hydrolyzed into ADP + Pi, which causes another conformational change in the head, increasing its affinity for actin, causing it to bind to the actin filament again, this time forward from where it was at the beginning. Pi is released, which causes the lever arm to return to its original position, pulling on the actin filament as it does so. ADP is then released, and another ATP binds the myosin head to release it and start the cycle over.

[@_HOLLOW_-ll7dj]

Who else revising the day before 🙏 🔥🔥🔥

[@xxFR12]

im going to nail this exam

[@jasminemirza5608]

Smooth explaination. satisfied😊

[@maari5011]

A long lesson withing few minutes 😍 Thank you so much❤️ Can you please explain slowly. because of This is fast for beginers 🤗

[@dannichols6261]

I feel your pain, but did you know that you can make the video play more slowly? If you click on the gear shaped icon under the video, it will give you a choice of speeds to play at. You can also turn on closed captions, and turn the voice off if you wish.

[@Kjk172]

Great video, still super confused though im gonna have to watch a few times lol

[@alonzosesay5457]

So amazing my 2 hours lectures explain in 2 minute

[@alokalliyanage7022]

Crystal clear explanation 👏

[@Hello-xz9yr]

Thank you! Very helpful

[@musicminds-official3174]

This video would be very good for revision

[@sunidhimalakar2764]

Very well understood....🙏🙏🙏

[@muhammadbaqir8895]

Thanks you clear my confusion...

[@eddyjabez5874]

Thanks 😊 that lady is crystal clear 😊

[@komal_potterhead7611]

I was always that ATP break before cross bridge formation or after crossbridge formation...now it's crystal clear.. Thank you😌😊

[@Pricelesspeace-w5s]

Mjhay sarcomere samjh n araha kya hai

[@SaraAli-cg3qj]

​@@Pricelesspeace-w5s area between two Z lines

[@ahadzx8875]

@@SaraAli-cg3qj so technically sliding filament actually occurs in sacromere right?

[@dannichols6261]

@@ahadzx8875 I think you are correct, and multiple sarcomeres are then stacked and connected one after another within the myofibrils, as far as I know so far.

[@ishan9924]

Can someone explain this to Me If we strap our hand to a machine which helps us move our hand move in and out and we let loose of it then how is it moving because we aren't sending neuro signals meaning the sites of bonding are still closed how is the muscle still contracting then??????

[@veerendraveerendra5080]

Thank you

[@jamesmungania8214]

Soooo clear!!

[@arpitsingh8711]

Thanks a lot for explanation.

[@freefirelovers-pw3wq]

Interesting video

[@HYPESQUAD-vj1ml]

Oscar winning legend ❤❤❤❤❤❤

[@sagarmb7222]

thank you so much ❤️

[@amnashaikh-sl1qi]

thank you so much!

[@chloelp6761]

Bro.

[@W_Incognito]

This topic is fucked up LOL, by far the hardest 😅

[@meiakkash0750]

i now really understood thank you

[@nakibh3823]

0:53

[@shamskabra]

We talking about all types of muscle in the body or specific muscles, like heart muscle. Asking because Troponin is found in the muscles of the heart.

[@rachel2953]

Brilliant amazing spectacular 🥰

[@MP4N876]

Perfectly condensed love it

[@r2fteachpe]

Thank you! It was the toughest one I have done but worth the effort. Wish I had time to do many more.

[@adhithyaajayakumar398]

Thank you for this

[@halambagetharindi5219]

Very good explanation 🙂

[@JAYGURUDEVDATT]

धन्यवाद माऊली🙏

[@mohammadmalahim8660]

Thanks 👍

[@nimasabri4000]

Great Video

[@HYPESQUAD-vj1ml]

Amazing

[@hindutvadj8082]

Nice yrr maja aagaya 👍

[@bibhuranjannath2534]

Well explain

[@hirrajamshaid3540]

Nice lecture

[@sarahmckil1900]

thank you sooo much

[@beabedonia8665]

Thank you!

[@nicocoscarelli3306]

Thank You! :)

[@thesudarsanmitra]

loved it

[@abigailmaag2426]

Does magnesium have a role in this?

[@HarshSharma-ns5ip]

Thanks

[@neelimapradeep9313]

Thank u sooo much 🥰🥰

[@dilan5188]

good job

[@r2fteachpe]

Thanks

[@sibaivan972]

Finally!! Peace ✌

[@komaldiptianandmaisuriya4301]

Ty

[@zenogarr481]

Amen.

[@verycd]

0:58 wrong spelling, "acetylcholine", not "acetylecholine".

[@redwingbasil]

Sorry this vid was really slow; try 2x speed Much better

[@ramrigoutofficial5984]

Any personal training students here?😂🤣😂

[@Mallu_runner]

😂

[@naidunaidu4115]

Better very little slowly......

[@vidyaharan.pramothayan6834]

2:00 Ca2+

[@midhunmk71]

💖

[@玛卡巴卡-p5e]

The myosin looks so cute

[@mskreidlerphysics3950]

Ca 2+ not Ca +. Acetylcholine = uh see - tul or uh-see-tl. Named after the acetyl groups in Chemistry. Not ass-e-til. Excellent illustrations + a few corrections in the voiceover = perfect.

[@nevracket3000]

ACTUALLY i THINK you'll find it's Ca TWO PLUS, not Ca PLUS. i think lol

[@chandanas-b9q]

Mam from where atp molecule bind to myosin during relaxation of muscle mam

[@user-hu9kt3ou5v]

ATPase (where ATP binding site is present) that is present on myosin head

[@RM-ng7mk]

Thnqq

[@manimubi7352]

👌👌💛

[@Tylanjamison96]

It's ca+2

[@angenaagenor458]

Thank you! I peeped that and scrolled to see if anyone corrected her in the comments...

[@nithyac5723]

Good

[@roshandontknow]

I never get the atp part

[@chasstone5048]

There at the end..my muscles are not able to relax back. It's hell. On any activity when I finally get loose (usually in water floating and stretching) it takes only a few minutes and i get super tight again. I had t9t10 damage in spinal. Got one leg paralyzed but I was, am able to get that leg working after 3.5 years. My muscles in legs an glute are so tight, but I get them loose with hours of work and water..yet to feel them get so tight I can't walk after 100 yards. My Drs are clueless and really don't give a dam..

[@MS-vx1xt]

That sounds horrible Chas. Hopefully the Drs will figure out a solution for you soon. Wishing you all the best, stay strong.

[@DrIsrarAhmadnew]

I don't understand a little bit.

[@JamshaidWaqasLodhi]

best

[@juancheto0177]

Acetilcolina o calcio?

[@mina2005]

من طرف استاذ احمد على 👍

[@drx.aazamanasri3081]

Kon kon meenakshi mam k batane prr aya h yha 🥰

[@MOONLIGHT-nu3ks]

What I was imagining seems to be completely wrong. 😂

[@sidology1.0]

holy cow

[@vaishnavi8180]

Who all saw this video in 1.75 speed

[@ebrelus7687]

Not sucko but saRco.

[@qtkeiran1383]

cap!

[@anweshahazarika8073]

What d hell just happened

[@tryouts]

Isse mera kya fayeda mei tho commerce student hu🗿

[@carlosp6787]

I knew this video was going to be ratchet :D get it? I'll see myself out...

[@shifanathpkm182]

*IDK WHO MADE THIS BUT IT WAS ALL WORTH THAN 3HR LECTURES* 🥹🫶🏻❤️

[@ashleyshepard6032]

Thank you so much for this

[@deepapudasaini7629]

❤️