How to Prepare Pumpkin Puree 👇 Boiling Method: Boil the pumpkin pieces in water for 10 minutes. Blend the boiled pumpkin until smooth. Baking Method: Bake the pumpkin pieces in the oven at 350°F (175°C) for 20 minutes. Blend the baked pumpkin until smooth. Microwave Method: Microwave the pumpkin pieces on high for 4 minutes. Blend the cooked pumpkin until smooth.