Science says THIS is the ultimate hangover cure

[@SophsNotes]

A mate of mine swears that the ultimate hangover cure is a pack of BBQ Hula Hoops and a bottle of Lucozade (not #spon I promise). What are yours?

[@sheaedwards1999]

An odd one but the gym (only for a mild hangover though, i think if i was properly hungover my body would give up) a fry is my usual go to

[@SophsNotes]

A solid pair here. I feel like exercise works as a distraction more than anything, so I stop feeling so sorry for myself 😅

[@THE-X-Force]

It's important to note (9:15) that ibuprofen (or any medication containing a NSAID) raises the risk of severe stomach bleeding for people who drink 3+ alcoholic drinks per day during the same time that they take the ibuprofen. Just anecdotal, but I find the best way to "cure" a hangover, is too avoid getting one. I stick to clear liquors like vodka, on ice, with usually nothing else.. but you can add lime, seltzer, whatever, but what you're trying to avoid is anything sugary. That goes for all drinks. The sweet liqueurs and mixed drinks with coke etc (Jack & Coke for example: dark booze plus a high sugar mixer) are the recipe for a very bad morning. Along the same lines, for every 2 or 3 drinks you're having, try to get a fresh glass of water in you too .. or some Perrier, Pellegrino, etc. Much better to try to mitigate getting dehydrated, than to suffer and try and rehydrate the next day.

[@mothertrucker1262]

Why haven't you uploaded any video this year? Is everything okay

[@SophsNotes]

@@mothertrucker1262 All fine! I just took January off to do some planning/organise stuff to do with my day job :) New videos coming in Feb

[@jimsbooksreadingandstuff]

I came here from John Green's video, liked what I've seen and subscribed....

[@seanrshivers]

saaame :P

[@braininajar8474]

yup

[@Aris-gf9rq]

me too!

[@maggieo]

As have I!!

[@Corporis]

Veisalgia is such a wonderful science word. Equal parts inspiring, terrifying, and Norweigan

[@corngreaterthanwheat]

I'm a nursing student. I can't wait to drop that word on a patient note to piss off a rude resident lol

[@anna-ne9zk]

so glad john told me about you on vlogbrothers!!! already watched a few of your videos and you're definitely one of my new fav youtubers!! :)

[@brandonhenning9540]

"older and wiser and the pubs are shut" hahaha I laughed out loud.. Anyway, very informative thank you!

[@vgreen1156]

😂😂😂

[@juststeve5542]

1:45 - Don't break the seal! All I've learnt over the years is I can drink good vodka with my Polish friends and bounce back the next morning with little problem, but a few beers with my English mates mean the next day is a write off!

[@bloodgain]

Probably because the beer contains more methanol. That's a possible cause that she left out here that I've heard many times. We have a harder time breaking down methanol, and so it makes us feel like crap.

[@georgeprout42]

"Alcohol" (ethanol) alone can't cause the hangover. I'll happily drink a gallon of 5% Doodle stout (or other real ales) in a session and be absolutely fine. A single 330m bottle of Becks lager though and I'm dead with a thumping headache the following day. Could be the methanol idea, or something similar to allergies. Certainly we all have different reactions to different drinks. No wonder there's no definitive cure.

[@cwharton]

vlogbrothers brought me here! Great video

[@cameronh3756]

Hey me too!

[@C.Y.123]

Same, I subbed

[@cwharton]

@@C.Y.123 yep, me to. This channel is a gem.

[@Aris-gf9rq]

me too!

[@stormd]

The best hangover cure I've found is a hot bowl of Pho. Tons of liquid, salts, just the right amount of grease, presumably casein in the fat brisket I usually get as a meat option, and starchy carbs for a quick energy boost, I've never not felt better after downing that combo after a night of drinking.

[@ItzAzarah]

Waste of time don’t bother wasting time !

[@thebuzzah]

FYI drinking while watching. When I was younger, I actually had brutal hangovers. It's probably moderation by wisdom that they are not so bad lately. I have to say that I have imbibed more in 2020 (thanks, pandemic!) than normal. I haven't had one of those extreme hangovers in quite a while though. Also, I found this channel through John Green/Vlogbrothers. I'm always up for new stuff. I like it so far. Cheers.

[@karasirarichard3358]

From the vlog brothers... Love🔥🔥🔥

[@SophsNotes]

Welcome, and thanks for coming over!

[@alaindeturing62]

Happy holidays soph

[@SophsNotes]

And to you too! ☺️

[@AmosOfSynhome]

Dealcoholized drinks are an excellent hangover preventative! LOL

[@joshuashain5891]

I came here from vlogbrothers, but OMG is that 12tone in your list of Patreons?

[@nickebert1265]

After watching this video, I’m wondering why another popular (although obviously short-lived) hangover cure is to *continue drinking*. Any thoughts?

[@AllFloofAndNoThoughts]

Disclaimer this is an educated guess. Hangover is almost certainly more than just one cause. Continuing to drink gives your body some water which in the morning we need anyways. Alcohol is a drug so we do experience withdrawal symptoms so continuing to drink can mitigate that effect. Alcohol has a numbing effect so that probably doesn’t hurt either.

[@corngreaterthanwheat]

For the longest time, the treatment for mental illness was getting hammered. If you felt hungover from dealing with your depression, you could just start dosing again. Helps deal with the anxiety of sobering up too (Soph has another great video on that!)

[@clayz1]

That’s not really a cure. It’s just putting it off. On the other hand, if you are going to drink again, everything you do is just putting it off.

[@ErickandDerrick]

Great video! I'm with you, I thought hangovers were caused by dehydration. Thanks for the information, can't wait to watch more of your videos.

[@SophsNotes]

I'm glad it wasn't just me! Thanks for watching ☺️

[@Jesse__H]

I'm thinking tho ... the statement "hangovers are not caused by dehydration" is not the same as the statement "drinking lots of water before my drunk ass goes to bed will not help." Because that's what I do, and when I skip it I always feel worse 🤷‍♂️. Also it's not something I do _while_ drinking, so I don't think it's decreasing my overall booze intake as mentioned in the video...

[@unicornep1818]

Vimto and Fry's Turkish Delight, the best hangover cure in the world. Have a happy mid-winter festival of your choice, and a merry new year.

[@luisdanielmoreno5717]

Just discovered your amazing channel, keep up the good work 👌

[@guffaw1711]

I take Ibuprofen after too much drinking, so far it has always helped very well with the headaches, drowsiness and most of the nausea. However I still get slight feelings of imbalance but it's managable. I've read that its ability to mitigate the effects of a hangover was already known to its inventor Stewart Adams. Alcohol also degrades the quality of sleep quite drastically, so parts of its symptons should come from severe sleep deprevation. If you are a regular coffee drinker the coffeine withdrawal symptons will also be worse during a hangover, so don't forget to take your Ibuprofen with your morning coffee.

[@bsidethebox]

As a person who has battled chronic insomnia, I'd definitely agree that a lot of "hangover symptoms" align with the gross feelings following a bout of insomnia. I can't compare for sure as I hate alcohol and have only managed to down enough to get tipsy once in my life (where I found out intoxication just makes me want to sleep on the table so screw that) Stay up much later than usual (ain't no party like a can't sleep party) and sleep poorly whilst teetotaling and you'll still likely enjoy a queasy tummy, puffy face, slow brain, slowed reflexes, headache, dry mouth, etc.

[@johnnash2815]

A roll and bacon is hard to stomach when you are hungover? I think I found the problem here, you are not drunk, you are high!

[@daniellim8964]

Oily food is not so good for the gastrointestinal tract after getting seriously drunk.

[@Max-ph5in]

N-acetyl cysteine is great. Also a sneaky weapon in drinking games ;)

[@corngreaterthanwheat]

Do you supplement your way to victory in beer pong? *Slow claps*

[@yourtypicalwokestoner8117]

@@corngreaterthanwheat So messed up for the opponent though 😂😂😂😂😂😭

[@corngreaterthanwheat]

@@yourtypicalwokestoner8117 if you ain't cheatin' you ain't competin'! 🤣

[@yourtypicalwokestoner8117]

@@corngreaterthanwheat LMFAO

[@imapiraaate]

David Nutt’s research is so fascinating! Glad you mentioned it in the video :)

[@acidstrummer]

Thank you for not letting Tom Scott win that numbers card game in the pub

[@rosemarychadi7734]

Here from vlogbrother's video. subscribed!

[@JamieTheMime]

aren't you not supposed to take things like ibuprofen when you've had alcohol?

[@mattwill2643]

Magnesium works for me. I'd usually take 1 pill a day but when im hungover bump that up to 4

[@steffennylenna8889]

kveis or bakrus are norwegian words for hangover....greeting from the arctic circle

[@petronellataube2986]

Bakrus! Kul. Är det "rus" och bakrus sagen efter?

[@steffennylenna8889]

@@petronellataube2986 rus means something like (alcohol/drug) rush/high....and bak just means after

[@rptbr]

My cure (least what my body craves) is a big spoon of peanut butter, a pint of cold milk and something with sugar: et voila! Speaking of, interesting that sugar wasn't mentioned in this. I always thought as you're intaking a massive amount of "sugars" while drinking, then immediately stopping - felt it could be an overactive pancreas in the routine of processing this sugar, that by morning ends up mimicks a diabetic "low" (lethargic, depressive thoughts, feeling ill) - be interesting to see the glycemic index of the night before / morning after. #theoryforthemixer

[@SophsNotes]

Ah yes the sugar theory is another one I came across! I was squeezed on time so didn’t put it in but it definitely seems to have a part to play, and it’s interesting to look at how the components of different alcoholic drinks impact hangovers (with sugar being a big un). I’ll have to try that cure! Sounds like a good one.

[@mLyonJE]

I've long thought it wasn't really dehydration[*] and periodically consume interesting material on the many ideas, theories, and so forth -- like you say, all still a work in progress on many fronts. ONE thing though is how much it seems to help downing a pint or two of tap-water before going to bed after a night out. My hunch about this is that you're literally handing the body the very "vehicle" it utilises for doing so much of its regular work; and so, whatever it does to "process" toxins etc., it can do quicker and more easily with a quick top-up of the materials (water) it needs to operate. It's not actually dehydrated, it just makes everything going more easily and more quickly to have a surplus slosh into the system at that point. [*] Don't even get me started about everyone thinking we need 2.5 litres of water a day because everyone forgot it was the bottled water companies who told us that in recent decades!! I looked up the scientific paper from which the water companies seem to have drawn this information -- yes, 2.5 litres, followed immediately by a comment that 70% of said water arrives in the food we eat during the day... Yup, more like 0.75 litres of actual water during the day and if you have a glass of orange juice with breakfast, a cuppa or two here and there, a glass of water with tea, you're totally good to go. Not a single overpriced bottle of water in environmentally damaging packaging to be seen! #petpeeve Great video btw :)

[@levishaun8334]

Huh, this is interesting. Where I'm from, I don't think I have ever met a person who thought that hangover is caused by dehydration. I have extensive history of drinking with tons of different folks (kind of happens naturally when you only drink at a bar, but very often) so hangover as a topic have been brought up quite a lot. Literally everyone I ever talked to about it has said something along the lines of it having something to do with alcohol decay doing something or other in the brain. I haven't been drinking with your average alcoholic, but not all of them had degrees either.

[@JohnTaylor-xg4jn]

vlogbrothers sent me here. You have been chosen.

[@bloodgain]

One possible cause I've heard many times that you didn't cover is ethanol vs methanol. We break down ethanol first and have a harder time breaking down methanol, so we feel bad if we get a lot of methanol. So, at least in theory, the more methanol in the drinks (e.g. beer and wine instead of, say, vodka), the more we're likely to feel bad.

[@elijambu]

i was going to say this exact thing. I was surprised it wasn't even mentioned? maybe it was deemed irrelevant or unsubstantiated? Any comment Soph?

[@sparkdaniel]

Keep drinking, no hangover. Nice cold beer is a great cure

[@British_Rogue]

Dry mouth would be caused by the alcohol itself. Limits saliva production.

[@ArashiKorosu]

@vlogbrothers thank you for the recommendation, one more channel to watch regularly

[@JohnRochford]

The brilliance in timing for this video isn’t lost on me as I lay in bed on Boxing Day morning contemplating what to eat

[@stevebell9339]

Activated charcoal or more booze

[@rfldss89]

Professor nutt's work seems like some 'brave new world' shit and I'm not sure how I feel about it 😳

[@MrSagru]

A few liters of water before and after sleep + a handfull of ibuprofen and I am always up and running by noon

[@adamogilvie6951]

Eggs. Trust me. Lol!

[@eliannam.5700]

helloooooo! here from vlogbrothers

[@DeadlyMouse2024]

Facts and fun, fun fact.

[@caryrodda]

I seldom drink any more but I still enjoyed watching this. You make science very entertaining and easy to absorb.

[@corngreaterthanwheat]

Hangover Devil Sophie is 💯. Please make her a recurring character if possible. Also, when I drank, I'd also chain smoke. Since those are similar chemicals, was I making my hangover worse? (I eventually stopped drinking after chucking in an Uber and losing a day to self induced sickness)

[@SophsNotes]

Oh yeah I reckon that was like double layering your hangover Ryan hahah 😅 and I’m not going to tell the story that meant I cut down on drinking 😬

[@corngreaterthanwheat]

@@SophsNotes I left out the part where I walk 8miles up a mountain shirtless at 3am... You were a college student in London. I can make some assumptions lol.

[@TroopsofDoom666]

Im watching this video during hangover now....dafuq!! help me help me!!!

[@psa110]

Fryop? Fry up? Yes, was able to figure it out but... Jacob's Join? A full English? You've got to remember a lot of your fans are not British (I'm a Yank). BTW, maybe you could do a video on Desert Mouth. 😝

[@jerseylionesses]

I was hung over really bad i made soup broth just chicken bouillon salt pepper and Italian seasoning.. I boiled it and drank slowly it was great

[@FeintMotion]

MANGU

[@matthewdragomir2261]

Typing in "kveis" in google translate doesn't net any results yet go to wiki and it gives the exact same info as you presented here. I guess if the internet says it, it must be true? 🤨

[@DamnedM]

My body is a temple... ...to Grease

[@Matowix]

Also if u have a fatal drunk car accident u can avoid the hangover

[@NotKyleChicago]

7:32 - Was that "lowkey" or "Loki" in regards to the idiocy? 😉

[@tajusn4044]

Lass sounds like Captain Kidd from assassin's creed black flag

[@bigman5125]

I have found exercise definely works, though really not something you want to do when hungover.

[@roserands]

Well done Soph 😘

[@reddragon3132]

What causes the whole "breaking the seal" effect? Is there actually a biological cause for it or is it purely psychological?

[@matthiassteegmans8469]

your references are a bit outdated (1976; 2008; 2010). but i do think the subject is interesting indeed!

[@SophsNotes]

Yep I agree! We need some fresh research on the topic

[@TravisGilbert]

What does broken the seal mean in this context?

[@SophsNotes]

When you go for your first wee after drinking alcohol! After that it’s so much harder to hold anything in 😅

[@gravelrhoads]

I usually watch you on Nebula, but I had to come over to KZbin to make this comment: You are a wonderful fount of knowledge and your accent, tone of voice, and turn of phrase makes it even easier to absorb that knowledge. And yes, I have asked Nebula if they were working on a comment system and they told me, basically that it was still early days.

[@SophsNotes]

I've just seen this, thank you so much!! What a lovely comment, I really appreciate it :)

[@TheDarthReagan]

A buddy of mine's mom makes a snack mix that my friend group has begun calling the "Hangover Mix". Just eat a bunch of it before bed, and you'll be just fine!

[@SophsNotes]

Scale up the manufacturing and you'll make a killing!

[@ekaterinashum3024]

Ok and what is it????

[@Ajwontpay]

Did you encounter any research on hair-of-the-dog cures? They seem to be reasonably popular hangover cures (re: this comment section) but my first instinct is that it doesn't seem to make a lot of sense since it'd compound the issues already at play (whether dehydration or acetaldehyde or inflammation)

[@SophsNotes]

Yeah I had a short bit on it but cut it out ! Basically saying that the only reason they work is that they’re putting off the eventual hangover aka recovery of your body. So ultimately it makes things worse!

[@cheminlee37]

I live for that “probably” call out 😂

[@quefixxer2455]

Great content ... subd !!

[@karansaulakh8979]

Just don't drink

[@seanrshivers]

Lol, my grandfather is the guy who discovered Acetaldehyde... Dr. Richard Dietrich.

[@seanrshivers]

They may have allegedly used alcohol dehydrogenase (the enzyme which breaks down Acetaldehyde) in order to eliminate their hangovers :P in unapproved experiments ...

[@SophsNotes]

No way! That’s so cool. Hahah I was thinking as I made this I need to get hold of some alcohol dehydrogenase ...

[@seanrshivers]

@@SophsNotes If he was still alive i'd ask him how effective it was. :P

[@cameroncook3863]

Good job on the research girl 👍 All Makes sense to me

[@daniellim8964]

Oily food is not so good for the gastrointestinal tract after getting seriously drunk.

[@cameroncook3863]

@@daniellim8964 Hey you should do a review for Cheers. After drinking.

[@CraftDayFriends]

awesome!!

[@protocol6]

Nothing about hair of the dog?

[@SophsNotes]

I actually had a bit in but cut it out to keep the video sleeker. It was just the typical ‘you’re not letting your body recover and it’s a bad idea!’ response 🐕

[@aisekaisebc]

Works. Just not the most feasible method.

[@MrMessiah2013]

One chemical I can attest to from personal experience that has "alcohol mimicking effects" is Phenibut HCL. As far as hangover cures, I have also heard that Turmeric is good. Apparently there is a drink in Japan that is drunk prior to going on a bender that is essentially just a Turmeric shake and is very good for that from what I've heard.

[@GeoffCanyon]

The book Life Extension, by Durk Pearson and Sandy Shaw, recommended B1, C, and cysteine for hangovers 40 years ago. Unscientific, but it worked for my friends back then.

[@love1orhate1boxingnewsupda61]

Speaking from experience Water is the best one you feel yourself getting back to normal slowly but surely And no not no damn water bottle You need a jug or maybe 2 no 🧢 Great video btw

[@deathscythe767]

Drinking lots of water immediately after ditching the party people and possibly throwing up some of the alcohol if I had gone too far to wake up without a hangover usually does the trick for me. It's not a pretty answer but works. Also, barfing on command only happens when I get really smashed. Any other time that super power goes away lol