Pharmacology - ANTIEPILEPTIC DRUGS (MADE EASY)

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Antiepileptic drugs, also referred to as anticonvulsants, are a diverse group of medications used in the treatment of epileptic seizures. Antiepileptics work in a number of different ways to inhibit or slow down neuronal firing to prevent seizures from occurring. This pharmacology lecture covers topics such as pathophysiology and classification of seizures, action potential, excitatory and inhibitory neurotransmission (role of glutamate and GABA), voltage-gated sodium and calcium channels, AMPA and NMDA receptors, mechanism of action and side effects of antiepileptic drugs. Drugs mentioned include; Carbamazepine, Oxcarbazepine, Lamotrigine, Phenytoin, Topiramate, Valproic acid, Zonisamide, Gabapentin, Pregabalin, Levetiracetam, Felbamate, Tiagabine, and Vigabatrin.
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0:00 Seizure classification
1:07 Excitatory synapse
2:44 Inhibitory neuron
3:51 Antiepileptics - mechanism of action
7:26 Side effects

[@SpeedPharmacology]

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Huh, this is really interesting! I'm not a pharmacist or anything. I just have Epilepsy, its really cool to learn how my medications work! :)

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What if u took all the pills

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Hey..I have made a mnemonic on Antiepileptic Drugs... it's really convenient...can watch on my channel ↖️

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Stimulating an influx of chloride ions, gaba, delaying an influx of sodium and calcium. Thank you soo much for making it short and straight to the point

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Thank you for helping me understand what is going on in my brain (I take levetiracetam). I’ve always had a slight interest in pharmacology but you’ve pushed me a lot closer to this field.

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Thank you for your thoughtful comment!

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I’d decided to wait for a bit before studying Anti-epileptic Drugs because I knew that your new video would be out soon now. I’m so glad that I took that chance because this video saved so much time and made the concepts crystal clear. Thank you so much for the time that you put into these videos. It’s really hard to make such difficult concepts so simple. Thank you! ♥️

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This video helped me get a clear concept about anti-epileptic drugs and their mechanism of action! Thank you so much for this great video :)

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You made that so much easier to understand than my professor did! As an epileptic individual, thank you for helping me better understand how my medication works!

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Hey..I have made a mnemonic on Antiepileptic Drugs... it's really convenient...can watch on my channel ↖️

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[@exameasy5167]

Hey..I have made a mnemonic on Antiepileptic Drugs... it's really convenient...can watch on my channel ↖️

[@Wizardofaloy]

Thank you for this amazing video. I have epilepsy and take oxcarbazepine but ive never found any information about how it acts on my brain to prevent my seizures. I had no idea it was the sodium channels, i thought it was the chlorine channels. So thank for your great explanation about it

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Wow! Fabulous. Mechanism underlying seizures tied very well to meds. Impressive!

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[@lionsinescanor373]

great summary. Appreciate you!

[@timehunter9467]

This was really cool to see, I’ve taken several of the medications listed here (hated zonisamide) I’m on a mix of Lamotrigine and Levetiracetam at the highest dose my body can tolerate. I’m surprised they both work so differently, I guess my seizures just hard to control so surgery is the answer.

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This is brilliantly explained. Thank you. Very helpful for exams.

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