Statins and CoQ10

In this video I discuss CoQ10 and how that coenzyme relates to statins.
General:
Papers cited and charts presented are licensed under the creative commons license:
creativecommon...
Section 5 of this license is a Disclaimer if Warranties and Limitation of Liability
Mitochondria diagram licensed under creativecommon...
by Kelvinsong; modified by Sowlos
CoQ10 and Aging:
The cited paper entitled "CoQ10 and Aging" is written by Isabella Peixoto de Barcelos and Richard H. Haas, published in Biology June 8, 2019. At the time of this recording, a copy may be found at this URL:
www.ncbi.nlm.n...
Information in this presentation was in part extracted from this paper.
Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license
Diagram of CoQ10 levels in heart tissue by age:
From an article "Coenzyme Q10 supplementation - In ageing and disease, written by Jan Aaseth, Jan ALexander, Urban Alehagen in "Mechanisms of Ageing and Development" July 2021. At the time of this recording, this paper was available at www.sciencedir...
Reference to study showing HDL Increase, Total-C decrease, but no LDL, Triglycerides statistically significant effects was in this article:
"The effects of coenzyume Q10 supplementation on lipid profiles among patients with coronary artery disease: a systematic review and meta-analysis of randomized controlled trials", written by Mohammad Vahid Jorat, Reza Tabrizi, et al and published in "Lipids in Health and Disease."
At the time of this recording, this paper was available at: www.ncbi.nlm.n...
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DISCLAIMER: The following presentation and all presentations in this series are for informational purposes only and should not be used to diagnose or treat any medical condition. Please consult with your personal physician when deciding whether to treat or not treat any condition with pharmaceuticals or by any other treatment or therapy. In particular, never change dosage, stop taking medications, or change a therapy because of something presented in this series without discussing your options with your primary care physician or other health professional.
The author is not a medical professional and is presenting his own story, research, and opinions as they apply to himself, and himself alone.
If you think you may be experiencing a medical emergency, immediately call your doctor or dial 911.
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[@FSCHW]

I asked my cardiologist if it should supplement with CoQ10 when I started taking statins. He said i should not, because it would interfere with the anti coagulant I take (81 mg aspirin). CoQ10 increases coagulation.

[@mystatinfreelife]

This is an important point I was unaware of. If you are working with a cardiologist, I assume you have some identified heart disease. In that case it is prudent to listen to him or her. This applies to Warfarin as well as aspirin and I would think other blood thinners as well..

[@FSCHW]

@@mystatinfreelife yes. I had a valve replaced. But was on statins a for few years prior.

[@FloridaTrailrider]

Thank you for the information Ross. It was helpful. I’m 55 and on a statin which I don’t want to take but is helping me with some alter sclerosis. I appreciate the time put in for this.

[@caahacky]

Thanks. The late Dr. Stephen Sinatra was my intro to this subject.

[@marshcreek4355]

A very nice presemtation. Good information. It would be interesting to know if the PSK9 inhibitors like Rapatha and Praluent reduce CoQ 10 similar to statins. It seems they are becoming a go to alternate for physicians when their patients can't do statins or are diagnosed with hypercholesterolemia. I have a brother who just came off of statins after 20 years and really should have been supplementing with CoQ 10. His cardiologist never even mentioned it. 20 years of statins did a job on him.

[@mystatinfreelife]

Good question on the PSK9 inhibitors; I've never thought of it. I'll have to explore that. Thanks for watching!

[@leboonleboon1638]

Hey Ross great video love your stuff, keep them coming and have a great great weekend. Thank you again for keeping your promise of doing a video on the subject.🎉🎉🎉

[@mystatinfreelife]

Thanks again!

[@sharonnovelpakhare6884]

So what is the recomended dosage of CoQ10/dsy

[@sharonnovelpakhare6884]

Day*

[@mystatinfreelife]

I use the ubiquinol form, and 100 mg/day seems sufficient for me. It is usually well-tolerated (but then again, that's said of statins by some). I've gone as high as 400 mg/day with no issues when I was on statins. I'd suggest starting with the manufacturer's recommended dose.

[@robyn3349]

I did not tolerate the statin well. My cardiologist discontinued it ("For now," he said. "Forever," I thought!) and gave me double dosing of coQ10. I am still not recovered from side effects of the statin. Thank you for the information, I will continue with the coQ10.

[@mystatinfreelife]

It's a rare cardiologist who will at least go that far! Good luck.

[@lisahults3095]

I hope your feeling better .. it took me 5 months before the muscle pain went away … mag oil was an amazing help on my legs every night !

[@marcelruckenwind4563]

Hi, thank you for the video. How about bempedoic acid instead of red yeast rice? My cardiologist suggested to take this rather new drug for one month and have my blood checked afterwards to see if the LDL figure went down. It's still around 100/110 now and he's saying it should get under 60.

[@mystatinfreelife]

I have not heard of Bempedoic acid before. I will take a look at it.

[@mystatinfreelife]

I will be putting out a video on Bempedoic Acid next week. :-)

[@thekam3588]

Recently found your channel and you present a lot of great info. Have you read the ingredients of the bottle you held up?

[@mystatinfreelife]

Didn't read the ingredients, ran out of it and haven't replaced it yet. Will look before I buy more.