Guyton and Hall Medical Physiology (Chapter 27) REVIEW Glomerular Filtration (GFR) || Study This!

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[@levi4328]

3:23 as an important note, this text on minimal change nephropathy has been extensively changed in the 14th edition and no longer mentions the "loss of negative charge" as a central mechanism of this pathology.

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[@tomriddle8780]

Hey, why does the vasoconstriction of the afferent arteriole decrease the glomerular hydrostatic pressure? Vasoconstriction will increase the resistance which will increase the pressure right? For example in baroreceptor mechanism, when low blood pressure detected, our brain will send signals to vasoconstrict vessels to increase resistance which increases blood pressure. Why not the same mechanism, what's the difference here?

[@Kishin15945]

It will decrease the flow going to the glomerulus. like if you press a tube less of the fluid will pass through.

[@tomriddle8780]

@Kishin15945 hahaha I have already passed my exam but that makes sense, thank you for replying!

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