Histones

[@johnpaul4940]

the way you explain, makes all nonsense stuff and complicated study into simple and understandable education, is really amazing the way you teach us. thank you so much i had followed your clips since my GCSE

[@lutalemetruthkaselampao9199]

Every time I'm going through my medical genetics lectures I have your page open on a tab. This is so helpful, thank you so much!!

[@courtnie1783]

this is a great explanation! I just spent 2 hours trying to read a chapter of a textbook on this but you cleared it up in 13 minutes :)

[@shomusbiologyofficial]

Thank you so much for appreciating my efforts

[@ashutoshmandal6611]

I am a class nine student and was in a trouble to realize it but now I have gotten full concept. Thanks a lot.

[@shomusbiologyofficial]

You're welcome

[@jayaprakashc.a2941]

Amazing capacity you have to handle the classes. I am 63 yrs, but still enjoying your class. Best wishes

[@shomusbiologyofficial]

I am glad to hear that you're getting benefit from my lectures

[@tanushajaitly3169]

The way you explain the difficult topics is amazing.. I admire your way of teaching.. Simply awesome

[@RubberDuckie00]

everytime I'm lost and confused this guy saves me okay. THANK YOU VERY MUCH!!!!!!!!!!1 YOUR VIDEOS ARE SIMPLY SO HELPFUL THANK YOU VERY MUCH

[@ramyababy1618]

TQ TQ TQ TQ sooo much for all ur vedioes we are blessed to c u in KZbin brother becouse from last 3 semister iam following ur vedioes only very detailed information I hard from u I dint written in nodes also directly i attempted I am getting 80% from last 3 sems TQ bro

[@shomusbiologyofficial]

Thank you so much for appreciating my efforts

[@lamispjm4135]

THANK YOU ! YOU'RE THE DISCOVERY OF THE DAY IG ! 13 min felt like 2 min ❣️

[@temple2infinity]

Amazing how you make these sometimes complex mechanism relatable and fun...good job!

[@shomusbiologyofficial]

+temple2infinity thank you. Glad you liked my lectures

[@fazalrehman1227]

Omg..it is an amazing lecture...I was so confused for the concept of histones but now I am cleared very well....keep it up sir👍👍

[@shomusbiologyofficial]

You're welcome. Glad to hear that you're getting benefit from my lectures

[@vikram-jg9kf]

Good job Shomu! You have incredible passion for teaching.

[@lihanou]

For months I auto-skipped all of this guy's videos due to the accent. Then I watched one out of desperation, and it's extremely good wtf. I missed out.

[@shomusbiologyofficial]

Thank you so much for appreciating my efforts

[@giftokeyo1053]

Thanks... Amazing, simple, brief, clear and well explained

[@shomusbiologyofficial]

You're welcome. Glad to hear that you're getting benefit from my lectures

[@Hydra572HQ]

What you say at 5 minutes 50 seconds is not true. H2B-H2A dimer and H3-H4 dimer do not first combine to form a tetramer. Instead, two H3-H4 dimers combine to form a tetramer, and then two H2A-H2B dimers combine with the tetramer to form the octamer that will be wrapped in DNA to form a nucleosome.

[@niteshsah7259]

Hydra572HQ exactly you re right dude

[@imposter8345]

Thanks a lot

[@ewelinadabrowska5456]

@Porter Kyng nobody gives a damn bro

[@jedrzejgadua-zawratynski6573]

Thank you a lot ! You make this topic much more accessible for students !

[@trusfrated8222]

This man has a video on every topic I search for and I like it✨✨

[@shomusbiologyofficial]

Thank you so much for appreciating my efforts

[@babitatudu8184]

sir ur teaching skills r amazing. thank u for such kind of videos. 1000 likes for u sir🙂

[@newaveride3396]

This was a great explanation! Thank you!😊

[@shomusbiologyofficial]

You're welcome

[@nguyenvanbao4500]

Thank you so much for your share ! The interpretation is easy to understand.

[@chmuzamilgujjar6060]

Its a really soo helpful ...Bundles of thanks for providing us such an excellent site

[@socceromance8316]

Sir it's absolutely amazing..! The way u Explain everything is just incredible

[@shomusbiologyofficial]

Thank you so much for appreciating my efforts

[@anamikaseduspace4448]

really awesome kind of job u r doing ...otherwise students like us would have been in a huge problem. thanks for providing such a good lecture

[@shomusbiologyofficial]

Glad to hear that you are getting benefit from the videos

[@sananawaz5862]

your knowledge and specially method of teaching is really amazing ...

[@shomusbiologyofficial]

+Sana Rani thank you. Glad you liked my lectures

[@svadivu]

Very nice n simple way to explain. Keep up the gud work

[@shomusbiologyofficial]

Thank you. Glad you liked my lectures

[@rajanikumari248]

Your videos are awesome to understand and easy....

[@shomusbiologyofficial]

Thank you. Glad you liked my lectures

[@sinthyiaahmed5234]

Your teaching skill is amazing!!!.God bless you :)

[@shomusbiologyofficial]

Thank you. Glad you liked my lectures

[@farsanamj1281]

Thank you sir Your classes are very helpful🙌

[@shomusbiologyofficial]

You're welcome

[@mariajemimah2390]

Simple and direct into the point... amazing❤❤

[@shomusbiologyofficial]

Thank you for appreciating my efforts

[@juliagipson6129]

You have great energy. You make learning fun!

[@shomusbiologyofficial]

Thank you. Glad you liked my lectures

[@WaleedAlHarbi7]

0.6 mm is too long for the condense form to package inside the nucleus . But your way of information titling is wonderful .

[@arjunjichkar]

Pls teach us biology for NEET as well But in detail like this 🙏🏼 Amazing teacher

[@shomusbiologyofficial]

Thank you so much for appreciating my efforts

[@toyinkazeem8875]

thanks for this explicit and concise video

[@salomegob8532]

Hello ! It's not two tetramere of histones that make an octamere. It's one tetramere of H3-H4 + two dimere of H2A-H2B. I am not sure you said that in your video. Sorry if I made grammar mistakes I am not an english speaker.

[@arclliquid615]

Really?

[@krishnabaruah7185]

I m preparing for csir net Dec 2018 by watching yr vdos.. hopefully I'll let u knw about my positive result...

[@shomusbiologyofficial]

Thank you. Glad you liked my lectures

[@TheSUTI86]

WOW...Awesome Teaching Man...

[@ChandrachurMukherjee96]

Please make some video on non histone proteins as well (like the HMG proteins). Thank you, this video was awesome!!

[@rashmik671]

Very informative

[@shomusbiologyofficial]

You're welcome

[@ujalaabbas1861]

Nice explanation sir, thanks a lot... really I'm very grateful to you

[@shomusbiologyofficial]

Thank you. Glad you liked my lectures

[@AnitaYadav-wf7ee]

tnx sir literally ur way of teaching is amazing

[@sushmitasingho641]

Thank you so much for this lecture!🤗♥️

[@shomusbiologyofficial]

You're welcome

[@bokachagol]

thank you for sharing the knowledge

[@shomusbiologyofficial]

You're welcome

[@arclliquid615]

Shomu bhaiya tnk u ...

[@shomusbiologyofficial]

You're welcome

[@drahaskell1]

Thank you very much.... is there a video that explains the DNA in the mitochondria which do not have histones and how they become compacted as in the nucleus?

[@jaiyadav8205]

becose mit dna circle form

[@khurshaidanwar1580]

The cell size is 10 to 100μm in diameter and the .6mm makes 600μm, kindly clarify. Thanks. By the way your way of explaining is amazing.

[@unknown-mn9wo]

my final exam is tomorrow I hope that I get the highest score and you explained this very well:)

[@shomusbiologyofficial]

Thank you so much for appreciating my efforts

[@brent7803]

incredible teacher

[@MrCoolio1985]

Thanks, mate. fantastic explanation.

[@nirmala3187]

very interesting, induce me to learn more thank you

[@kulsoomjaved1164]

Can't believe this video is 6 year old, and i am watching it now.. people are taking advantage form six years

[@shomusbiologyofficial]

You're welcome

[@snowminnnn5021]

Hello sir! I think the best way to describe the way the histones and the DNA strand are arranged is called "beads on a string" Hope this helps! 😊

[@shomusbiologyofficial]

Yes

[@chibeniezung8037]

Thank you .it's really good n easy to understand.

[@shomusbiologyofficial]

+Chibeni Ezung thank you. Glad you liked my lectures

[@SamsungGalaxy-qb8xw]

sir, what is the function of Histone (H1) beside linking?? (if any)

[@bhuvanashreenagaraja5568]

wonderfully explained. thanku

[@shummu1458]

very nice shomu sir great explanation👍

[@prachigupta6328]

Thnq for the knowledge u share..

[@shomusbiologyofficial]

You're welcome

[@lameaahmed1580]

thanx a lot..amazing exlanation

[@priyayadav1935]

sir euchromatin lecture is very good thank you

[@zeroeightmadeline]

Well Explained

[@shomusbiologyofficial]

Thank you

[@poonamdixit321]

great video sir.plz make some video on colligative properties

[@shomusbiologyofficial]

+Poonam Dixit surely do

[@SnehaKumthekar]

Please help: Are the nucleosomes at regular distance from each other? If not what is the reason?

[@sandichi2749]

so helpful. thank you

[@shomusbiologyofficial]

You're welcome

[@ompalsingh3129]

Thank you so much bhai😭

[@shomusbiologyofficial]

You're welcome

[@ijazkhan8419]

you are doing a great job at such a young age, kudos. I am your student if you accept.

[@privalgondaliya2628]

2 questions.... why some receptors are stable at cell membrane & why other are at cytoplasm ? what is novel mechanism of stability of protein?

[@Diogenesthedog0]

My Knowledge is kind of Naive but it has something with Hydrophobic and Hydrophilicity of Proteins associated with the Receptors.

[@ankitasingh2820]

Thnku sir for this lesson ☺️

[@shomusbiologyofficial]

You're welcome

[@ahsankhan-bl6yu]

amazing.....

[@shomusbiologyofficial]

You're welcome

[@VishalJoshi_Dani]

Just becouse of you i complet my msc without attending classes... Thank you so much...

[@shomusbiologyofficial]

+Vishal Joshi glad you liked my lectures

[@HarshPandey-rn2nu]

Don't tell huge lie like it.

[@erannoor]

Excellent!!!!!!!!

[@_atifch]

well done sir, keep it up

[@shomusbiologyofficial]

You're welcome

[@AnitaYadav-wf7ee]

sir plz tell me where is methylation or acetylation occur at c or N terminal

[@pratikkumarsinha1296]

Tq sir for your efforts

[@shomusbiologyofficial]

You're welcome

[@shivamssw937]

Really helpful

[@_charmeow9378]

what are non histones and its functions?

[@VijayKumar-kz5qg]

Bhaiya what is this N tail... Could please explain me i am in class 10 that's why I am not getting it

[@ashwaqkhalil655]

thanks for simple explanation :)

[@betulseyhan5968]

Hi. Can ı ask your something? where is the Histon1?Video is sucsessful.

[@aritribhattacharyya]

Sir what about the H1 histone protein?It does not form a part of the nucleosome but it forms a part of the histone family.

[@reshmasamanta4845]

thank you so much

[@shomusbiologyofficial]

+Reshma Samanta you're welcome

[@TheLaur113]

Thank you so much!

[@soumyakundu1811]

No sir, I think h3,h4 formed a tetramer, then it bound to the DNA, recruits two copies of h2a h2b dimer and completes the octamer in this way. but u said that the (h3 h34 h2a h2b formed a tetramer)*2.

[@shomusbiologyofficial]

I said that all these 4 subunits formed octamer presenting 2 times each. I didn't cment on the sequence of their arrangement

[@soumyakundu1811]

@@shomusbiologyofficialBiology ok sir, got it.

[@MohamedIbrahim-rg7dh]

You are so F so smart!

[@kanaksethi8124]

sir ye feet wala data kaha se leya mujhe dout h ye wrong h

[@botanywale]

Sir, what is the ratio of protein and DNA amount in chromatin?

[@addisalemtesfaye4592]

thank you too

[@shomusbiologyofficial]

You're welcome

[@jiyathakkar8456]

What is the angle DNA form during entering the histone octamer?

[@SumanSharma-wl3ld]

Here u mentioned that H2A and H2B are exist near entry and exit site while in your histone and nucleosome video from chapter 7 , you explained that H3 and H4 are near entry and exit site.🙄

[@majibarrahaman8987]

Sir...why histones are highly conserved ??

[@MUHAMMADAWAIS-se1yo]

Thank u so much .Your videos are helping me a lot

[@deepanshuadhikari4724]

what is that exit site sir..?

[@kudzaimatukeni4778]

Man.. U just awesome!!

[@shomusbiologyofficial]

Thank you. Glad you liked my lectures

[@luckygupta6519]

Somu bhai ke jai ho

[@shomusbiologyofficial]

Thank you

[@ladyinred396]

What about H1 type of histone? Should be 5 types

[@muhammedyousafk4115]

Thankyou sir❤

[@shomusbiologyofficial]

You're welcome

[@nazia2737]

Please do a video on dna packaging sir...

[@simranpareta9807]

Sir Is Every time histone protein will be dissociate after the modification process ?

[@am_rk02]

Thank's dr💙💙💙

[@shomusbiologyofficial]

You're welcome

[@isratmim3302]

Gd teaching sir

[@shomusbiologyofficial]

Thank you. Glad you liked my lectures

[@dattashinde7775]

Excellent information, l but there is a need of explanation speed should be slow, it is to much fast.

[@aakubhandari9699]

Perfect sir ❤️💯💯

[@shomusbiologyofficial]

Thank you