John Ioannidis: The role of bias in nutritional research

[@teddayer6523]

This man should receive the Nobel prize. It’s ridiculous how researchers (which I was) are so touchy about their work. Especially once it’s published. Publication and peer review is NOT a guarantee of correctness.

[@Max10294]

Professor Ioannidis .Your are courageous and passionate about spreading the message of good nutrition .I want to express my gratitude to you and hundreds of visionaries for using your scientific knowledge that is available today in the field of nutrition .And the recent Covid Pandemic

[@teddayer6523]

Prof. Ioannidis, my Dr colleagues start to wake up thanks to you.

[@reinerwilhelms-tricarico344]

Professor Ioonnadis should write a health cook book merely based on what he can believe is healthy - and make it public domain. I trust he would avoid most known mistakes.

[@HeyYall398]

Love this! Thank you dear for sharing.

[@larisaconstantinou]

It sounds like situation in nutrition science is doom and gloom.

[@bjorn2fly]

Unfortunately I also have the same impression, that its more or less impossible to get any meaningfull data out of our current research. Me personally think that if the scientist could answer a single key questions, it would be enough. How to eat if you have insulin resistance would be that key question. If this question could be answered, and people followed the advise, decieses such as diabeted, overweight, heart and arteries decies and altzheimer would also go away, since they have all been shown to depend on insulin resistance.

[@EricM93]

That question is answered. A no carb diet/keto diet solves insulin resistance and type II D in a matter of weeks to months.

[@MrBlaxjax]

The ridiculous thing is that the NHS in the UK advocates consumption of starchy vegetables , sugary fruit and grains even to people suffering from diabetes. This is dangerously ludicrous. Essentially we have had 40 years of dietary mumbo jumbo. Surely given the total mess that is dietary advice it might be best to stop giving advice. In the UK we used to be skinnier with apparently better metabolic health back in the day when we basically ate bacon and eggs for breakfast and pork chops peas and boiled potatoes for lunch. The switch to fruit fruit juices pizza pasta loads of bread and low fat everything has been an unmitigated disaster and just needs to stop immediately. We have 10 year old with fatty liver disease. Current dietary advice is a nonsense.

[@alansyoutubechanneluk]

"We need more data sharing", "Studies are not published", This surely is criminal that we don't share everything. I thought that was the whole point of the scientific method?

[@Caladcholg]

Really top-roped that last question asker, didn't he.

[@nicmart]

I wonder why debunkers don't take on the absurdities of psychiatry. There's not a single psychiatric diagnosis that can be validate by an anatomical or physiochemical test, yet it's still accepted as a science. Frankly, it does not better than chiropractic. I'm afraid that faith in the religion of mental health is so strong that barely anyone gives it a second thought. At best they ask, "Do antidepressant drugs work?" But what is depression?

[@hazynpeterson4083]

at red meat, eggs, cheese. No bread, pasta, potatoes, oxalate heavy vegetables ( spinache ) SUGAR,, SEED OILS . Humans do not need carbohydrates

[@nicmart]

You apparently have no idea how foolish your post seems under this video.

[@IronJohn755]

The biggest problem with nutritional research is the need for "science" meaning randomized control studies, etc. The effects of food on health take too long to manifest, and nobody will follow the design of the study. Most published papers on nutrition are too narrowly-focused and amount to the 5 blind men groping at an elephant. A perfect example is the role of insulin resistance in type 2 diabetes. Is it caused by some mysterious process like "adipose inflammation"? Is it caused by excess glucose in the bloodstream? It's a very simple question to answer - it's caused by dietary fat clogging the endothelium. But the interests vitiating against a criticism of dietary fat (ie the meat & dairy lobbies and people who love to eat fried chicken) make sure to never ask the question. There are three tools we have to figure out what to eat: 1) epidemiology - what are the outcomes in large, stable groups of people with different cultural dietary trends? 2) Comparative anatomy - looking at what apes and other animals eat in the wild and trying to draw some conclusions about the ideal human diet. 3) Anthropology - what did people eat in the past? You really don't have to be a genius to determine that humans are designed to eat plants - primarily storage organs like tubers, roots, grains, legumes, seeds, etc. Meat is simply too hard to catch, to prone to spoilage, and too likely to cause death without the advantage of fairly modern technology, freezing cold climates, storage innovations like smoking, etc. We are not lions who can run down a gazelle and eat it before it gets colonized by parasites. Surely humans ate any meat they could find (turtles, crayfish, bugs, an occasional large mammal) but it is not a reliable survival strategy. This observation is aligned with the epidemiology (ie the China Study), the comparative anatomy (chimps & gorillas are 95% frugivorous, and we have more amylase enzymes), and the anthropology (ie pre-Columbian native Americans primarily ate acorns, lotus seeds, wapato, goosefoot and other widely distributed plants.) It also elegantly explains every chronic disease (like the diabetes example above) as the result of eating a diet our body is not equipped to metabolize. I'm glad Prof. Ioannidis even dared raise this question. The truth is obvious, but people prefer to hear good news about their bad habits.

[@msinbalony]

Yet again, another comment full of bias on a video talking about why there is so much bias in nutritional science. Yes, I was repeating all these like a parrot in the 5 years I was a vegan. Then my body woke me up. We cannot flourish long term on plants alone, and it is enough to look at quite a few long term vegans and see that for your own eyes. Stop seeing nutrition as a cult and ideology. Stop committing to nutrition plans like it's a love relationship. Just listen to your body and be open to hear everything, because science itself is struggling, so you for sure should not think in black and white. This is my take, that I've learned first hand on my body.

[@mfloyd1556]

@@msinbalony Listen to your body. So true.

[@tohopes]

"the biggest problem is the need for SCIENCE. gah! *i already KNOW what everyone needs to do." lol

[@nicmart]

We found our true believer.

[@nicmart]

@@mfloyd1556 Almost every body says, "eat potato chips."