Hyperinsulinemia causes by Benjamin Bikman

What are the causes of hyperinsulinemia? Benjamin T. Bikman, Professor of Cell Biology and Physiology at Brigham Young University, explains what insulin resistance is and why it's relevant. Up to 46% of adults worldwide have metabolic syndrome, also called insulin resistance syndrome. It connects every non-communicable chronic disease, from the big ones like heart disease, diabetes and cancer to scary ones like migraines and dementia to less lethal but still very relevant ones, such as fertility problems. All are a derivative of one common problem: insulin resistance.
@bbikman1 explains insulin resistance as the failure of some cells to respond fully to insulin, leaving insulin levels high. There are three primary causes of insulin resistance: stress, inflammation and hyperinsulinemia. Stress is defined by elevated levels of the hormones cortisol and epinephrine, both of which want to increase your body's blood glucose, making them antagonistic to insulin. Sleep deprivation is the most common cause of stress. Inflammation is caused by cytokines, which occur with an infection, illness, autoimmune disorders, air pollution - including cigarette smoke - and enlarged fat cells. Hyperinsulinemia happens when there is too much insulin in the body and the body starts to become resistant to it. The body is conditioned to resist any constant stimulus.
Hyperinsulinemia is a cause and a consequence of insulin resistance, Bikman says. Watch the video to learn what insulin does and why hyperinsulinemia has become so common. Bikman's talk is followed by a Q&A.
Bikman earned his Ph.D. in Bioenergetics and was a postdoctoral fellow with the Duke-National University of Singapore in metabolic disorders. Currently, his professional focus is to better understand the role of elevated insulin and nutrient metabolism in regulating obesity, diabetes and dementia.
🥗💡 This talk was presented at the recent "Food for Thought 2023: Rising to the challenge of obesity and diabetes" conference held by Swiss Re Institute and @TheBMJ. Learn more: www.swissre.com/institute/con...
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#health #diabetes #insulinresistance #stress #sleepdeprivation #metabolicsyndrome #carbohydratemetabolism

[@user-gv5mo1rd2p]

I wish I could go back in time and make myself watch this talk. Stress and bad eating is never worth it.

[@saxgirlhornboy6458]

Amen. 🏆

[@kostar500]

You can’t do that but what you can do is everything from now on

[@dahof2789]

Bikman for the head of the FDA! Imagine the panic from big food and pharma. They would systematically destroy him!

[@m.esmeraldacaceres3171]

And I wouldn't even be surprised if his life would be in danger... It's so bad!

[@jelizabethpetrie6656]

Dr. B is one of the canaries in the coal mine. Unfortunately the govt.’s will never let the honest and helpful make the world healthier.

[@yvonnekiwior9633]

🎉🎉Brilliant Man!❤ I celebrate this MAN! A gift to humanity 💝

[@jackfournier2003]

Bro is killing it in that blue sweater. I love Dr. Bikman!!

[@szghasem]

Knowledge is truly power. Thank you Dr. Bikman for educating and empowering all of us, including many physicians that are willing to learn!

[@laraii1]

❤😮😅😊

[@schigara]

"Stop pouring carbohydrates down your stupid neck!!" ~professor Bart Kay~

[@wocket42]

@@MajesticArtimus almonds are the worst. They are not food for humans! I'm zero carb, but I'd rather have the pure glucose than the almonds.

[@iremkayan3298]

​@@wocket42 why?

[@OIOnaut]

This is signifficant. Not Ben talking here. I have been following all, yes all the names dropped plus 100 x more for ten years, reaped all the benefits too. So what is so significant here? An insurance company of insurers hosting this conference. That is progress.

[@kenpumford754]

What a different world it would be in terms of the burden of chronic disease on population health, and on government and private healthcare expenditures, if this was common knowledge!

[@eugeniebreida1583]

You said it!

[@murraypooley9199]

I think this is largely common knowledge. What point is there telling a herion addict to stop useing herion because it will harm them? People are addicted to their health problems. How often do I hear it said "my arthritis" or " my ( fill in the blank)". We humans are comfortable with our problems, we own them. Once the subconcious mind is programmed the conscious mind does not easily regain control.

[@ArdGeal]

@@murraypooley9199 Spot on- My brother smokes, and is an alcoholic and (poly using) heroin addict despite being on PRESCRIBED methadone, pregabalin and diazepam....he's a wreck but he loves being the victim and it's all societies fault that he's that way.... state dependent emotionally immature pr*ck....

[@Ge1Ri4]

​@@murraypooley9199 the addiction comes from our food supply, which is deliberately manipulated by manufacturers to provoke addiction. Why? Profit, of course! And this profit model dovetails nicely with the manufacturers of pharmaceuticals that treat symptoms without treating the cause. Why? Lifelong profitable customers, of course!

[@calista1280]

Our gov has created a population of weak complaining victims... A far cry from the Greatest Generation of WW2 Survivors and Thrivers! If only they had been focused on our actual health and well-being instead of greed and profits! 📈 The SUGAR & GRAIN CORPS LOBBIED GOV & THE FOOD INDUSTRY WAS ALLOWED TO LIE TO US!!! If only we knew that SUGAR, REFINED CARBS & PROCESSED FOODS ARE BAD FOR US... The truth is that ☆FAT is GOOD: chicken skin, meat fats, lard, butter etc are GOOD FOR OUR BRAIN, NERVE AND MUSCLE HEALTH! SPREAD THE WORD, GET BACK TO BASIC WHOLE, ORGANIC FOODS! ☆IF:Intermittent Fasting helps detox the system and jumpstart the weight loss journey. We would be a healthy, pain-free society without refined carbs & processed foods... 😢 I have almost eliminated my Fibromyalgia & arthritic pains, low energy, brain fog and sleep issues! Rebuilding my body back into my healthy, happy, active and quick minded youthful self again!!! 🎉😂

[@kathybaughman109]

I don’t give drs a pass but from my own family experience many would rather eat the jelly donut and reach for the insulin later than to give up jelly donuts. Some of us have this entitlement to eat poorly and expect the dr to give us an rx to get through the short term. The standard of care will continue to support those who insist on that standard through their own addictions and lack of personal accountability.

[@melissal3383]

100% agree…. They’d rather pop a pill. science is now proving that those pills don’t do much of anything. Sadly, the public would rather believe that a magic pill will come save them one day. Buy stock in Eli Lilly Ozempic or wegovy manufacturer. I don’t think it will be the magic pill but the public sure seems to believe it

[@thomashughes4859]

14:38 - This is when "the silence" will become deafening because the children are invariably doing something very dangerous. Be happy with lots of noise because the kiddos are just fine. ❤️

[@carolinelewis952]

I messed up last night and ate tortilla chips at a restaurant and this morning a horrible migraine woke me up and I threw up many times. No more deviation for me!

[@AnneAlready]

Excellent presentation. Thanks for sharing.

[@martinzero3726]

Great stuff!

[@milantoth2045]

Amazing presentation, thanks a lot 🙏

[@roadhousepress]

Question: acute pancreatitis. Why doesn’t anyone talk about this? Pancreas produces insulin. I wish you would discuss this. So many of us have no real answers about how to fix pancreatitis.

[@christianvelez7295]

Hello, anyone know where I can find the other talk. Or the other lecture?

[@zenzenzenx]

What about in addition to those unhealthy, sedentary lifestyle; muscle loss due to aging (sarcopenia) will surely cause a situation where less cells are receptive to insulin/glucose? What would the correlation to fatty liver/pancreas accumulated over many years and resultant in hyperinsulinemia in aging individuals? These fatty liver/pancreas would surely grow so large/numerous to result in higher chronic inflammation?

[@rustymorning431]

Would surely.... is yet to be tested.

[@HaHaroni]

I think I'll have some seed oil. What could go wrong?

[@dahof2789]

Spontaneous Human Combustion!! 😂

[@Nju1]

Is there medication for hyperinsulenemia?

[@chrisconklin2981]

Thank you, I think Dr. Bikman has improved his game. I have always wondered about the causes of insulin insensitivity and felt that his explanations were insufficient. A lot of low carbers wish to demonize carbs and I think that Binman has moved to a better understanding of the process. This time he recognized lipotoxicity and talked about glycemic levels. He used the term "Overeating Carbohydrates" which is good. He touched on hyper processed foods and showed charts of high multiple short duration spikes. There is a lot of fear mongering about insulin spikes. The danger is prolonged spikes. Using the glycemic index one is able to moderated spikes while avoiding over processed foods.

[@eugeniebreida1583]

I would love for you to timestamp the ‘lipotoxicity’ reference. I missed it, listening again, but would appreciate a pointer. YES finally a Bikman talk which was not focused on low-carb, but the tragically Multitude of factors causing Insulin Resistance/HyperInsulemia.

[@chrisconklin2981]

@@eugeniebreida1583 My point is that Bikman is coming close to the Lipotoxicity hypothesis . At TM 15:50 Bikman begins to talk about Ceramides(a lipid). At TM 17:00 he presents strange statements about the blocking of insulin and the result of insulin. I am afraid I do not follow his train of thought. My belief is that intracellular excessive dietary fat interferes with cell membrane insulin receptors.

[@saxgirlhornboy6458]

The danger is *prolonged* spikes 🤔 Reference?

[@chrisconklin2981]

@@saxgirlhornboy6458 Why don't you lead off and tell me your position - with references?

[@wocket42]

The best way to use the glycemic index is to only eat food where the glycemic index value can't be measured. If this sounds strange to you, you may not have understood yet how the values are measured.

[@anonymoususer7606]

20:29 I am an individual that responds to protein. Glucagon? I suppose that will be next area of research can anyone point me in the right direction. My mental health symptoms after an eating too much protein can be worse than those from eating any carbs

[@zanna660]

can the beta cells die making reversing insulinresistens impossible ?

[@goldstar846]

My dr refuses to give me a fasting insulin test because I pass my sugar fasting. laughed at me mentioning hyperinsulinemia an insulin resistance, not a chance of getting a1c checked he said...welcome to australia.

[@susangrande8142]

At least in the U.S., you can get your blood labs tested by an independent company. Maybe in Australia too? 🤷‍♀️ I hope you find a way around this problem. Can you go to a different doctor?

[@goldstar846]

@@susangrande8142 hi susan yes! I did indeed thank you .but most people dont realise they can .

[@dalialovesdoggies4361]

many docs dont even know what this test is all about. CHANGE DOCS. LOL

[@AnHourOfWolves]

To be fair, he grossly misrepresents macro nutrients. When he says 'carbohydrates' he's specifically referring to ultra-processed carbohydrates, and not whole grains, beans, fruit, and vegetables.

[@rustymorning431]

No, he referred to carbohydrate. There are only carbohydrate, “fat“ and “protein“ in maco. Whatelse?

[@AnHourOfWolves]

@@rustymorning431 In the video at 19:07 he explicitly states that the carbohydrates he's referring to are ultra-processed foods "this is not fruits and vegetables", "highly-refined starches and sugars". The research clearly shows that whole, intact plant foods - including fruit, grains, and beans - are associated with reduced chronic health risk (and reduced diabetes, and those foods are also low in fat and excluded from his analysis. The whole carbs/fat/protein concept isn't that simple, there's a night-and-day different between refined sugar and whole sweet potatoes or whole oats. The fact that he doesn't even acknowledge the health-promoting role of plants makes me think that his arguments are based on something other than the scientific evidence.

[@sorrykay3450]

@@AnHourOfWolves But he does say he's not talking about greens or roughage in the 70 percent carb that most people eat

[@barblacy619]

I was oxalate poisoned from superfoods and any amount of wheat gives me nocturnal anxiety. One raw kidney bean can kill you. Carbohydrates? None are essential and no thank you. Focusing on a steady diet of essential fatty acids and essential amino acids has made me healthy, strong and no longer inflamed. My joints are flexible and no longer hurt. Plants want to kill you with toxins check out Dr Anthony Chaffee.

[@simonwiltshire7089]

Nope. He means carbs. Pears and bananas are full of carbs for example.

[@OIOnaut]

All the problem foods here are less deuterium depleated, also this combines his stress and hyper insulemia as different causes. Leptin melano cortin and POMC STORY. It is light issue ans foos is a solar radiation barcode if any.

[@KenJackson_US]

Does meat have a lower percentage of heavy water than starchy foods? By what mechanism?

[@wocket42]

@@KenJackson_US yes, meat and fat are lower in deuterium. With plants it differs largely, depending on plant and water source. I think higher/lower is just how the plants/the animal cells do accumulate it or not and maybe a bit the water source (high altitude mountain water or not). In the end, the solution is simple. Just eat fatty red meat and you and your mitochondria will probably fine.

[@KenJackson_US]

@@wocket42 I _do_ eat plenty of fatty red meat. Though I'm skeptical about any mechanism that reduces deuterium.

[@starparik]

Query - How do we co-relate these findings to the French Paradox?

[@melissal3383]

@@starpariki saw a French woman talking about that paradox. She said French women are extremely vain. They will basically fast if they gain weight. If they are insulin sensitive then this approach will work just fine. BUT if a person has high insulin levels or is insulin resistant then the human brain cannot access the energy from fat cells. And the drive to eat CANNOT be ignored. Ben Bikman says “Hunger ALWAYS wins”. He explains this in a different video. We have to become insulin sensitive FIRST in order for our bodies to utilize our fat stores. This makes it VERY obvious to understand why a heavy or obese person fails over & over on the recommendation to “eat less & move more”. Or even a carbohydrate addict. Ultimate failure protocol that we see happening everywhere.

[@unitedintraditions]

I did Atkins diet most of my life. Developed high Uric Acid (gout) and Hyperinsulinemia 316 pmol/L. What most don't know is that meat raises your insulin as much as some carbs. When I switched to a whole plant based diet (whole grains, legumes, fruit) with some fish and chicken, I no longer take Berberine and Allopurinol for my uric acid. My fasting insilin is down to 110 pmol/L. Look up Low Carb and Insulin Resistance. Bikman talks about OVEREATING carbohydrates how it affects fasting Insulin. OVEREATING of anything affects your insulin. OVEREATING meat raises your insulin.