Synthesis of ATP (2018) Drew Berry and Franc Tétaz

[@aisutistoto5771]

The music Synched with the turning of the molecule is epic as hell.

[@devinseth6805]

It feels like doomsday is approaching and the mitochondrion being the bringer of it

[@armoredfight]

Its like lightning in a bottle! 🌩

[@Java_RAM]

Mitochondria is the best guy I have ever seen

[@thommyamnesiac]

with every video, I am humbled and my mind is completely blown apart. I'm a visual learner and this series has been nothing more than a miracle. Thanks!!!

[@bestryfulhd2102]

It not a miracle, a creator created .. very simple . But it can be a miracle if it just came without a creator .m that would be crazy 😱

[@MrSupasonik]

​@@bestryfulhd2102 Then who created the creator? This only shifts the miracle up the chain of creation.

[@bestryfulhd2102]

@@MrSupasonik nobody created the creator . Creator is perfection of everything, independent and self sufficient that's why he eternal . Matter is dependent so it can't be eternal cause it depends in someone to make it exists . But we are going to die and we will see hell and paradise ..

[@weltschmerzistofthaufig2440]

@@bestryfulhd2102 That makes no sense whatsoever. According to you, humans need a creator, but the creator of humans does not need a creator.

[@DepletedUrbranium]

@@weltschmerzistofthaufig2440 just because you can kick a can down the road does not mean feet don't exist silly. Every other cause you accept is proximal, but you don't deny it just because you don't know the ultimate cause. Start here, "I think, therefore I am". It does get harder, but if you deny that you exist just because you don't know your ultimate cause, then you can't even begin to start thinking.

[@musicalBurr]

These animations always blow my mind, they really let me think about biology in ways that I never would have before and I think help my understanding beyond just watching stuff move around. Wonderful work!!

[@xtldc]

The 3-dimensional structures of each of those moving parts in these animation were figured out in labs by scientists who specialize in a field called structural biology. It’s really cool stuff, you should read up on it if this kind of stuff interests you.

[@musicalBurr]

@@xtldc Thank you, I will!

[@delq]

I cant imagine how life finds order amidst this seemingly uncontrollable chaos. Brilliant animation !

[@xtldc]

A lot of processes in biology (and chemistry) come down to 2 major factors - electric charge (opposites attract and like repels like) and physical size/shape (complimentary shapes fit together like a key in a keyhole - if a key is too big, it won’t fit in a keyhole - if a key is the wrong shape, it won’t fit in a keyhole).

[@Mohtellawi]

It is one of the reasons why my belief in God strengthened while studying medicine. "and consider the creation of the heavens and the earth, (and say): Our Lord! Thou createdst not this in vain. Glory be to Thee!"

[@odraz0101]

And if you dare to study evolution itself instead of just medicine your belief would be gone, because of how little it takes to start accumulating complexity at an insane rate, in this systems, and you would be wondering why it took life so long to come up with intelligence.

[@delq]

@@odraz0101 i do understand that complexity is inevitable for sophostication and intelligent processes but one cannot stop but end up personifying this intelligence clearly because its different from other forms of random complex activity that is complex but not so interesting as life. And the fact that we differentiate life from other equally complex activity shows that we value it for its inherent beauty. Everything is complex and much of everything is described by mathematics and other sciences. But that doesnt make the underlying structure any less worthy of appreciation for their beauty. Complexity allows for intelligent and interesting phenomena. But the intelligence and interest is an attribute of the respective processes not of complexity.

[@RickyPollo]

@@xtldc Physics is fundamental! This is why our HS science department teaches physics before biology, so that students can try to understand the interplay between charge, shape, and function. We're working on getting chemistry to come after physics, so that we can teach these things in the order in which they are best understood: 9th grade physics, 10th grade chem, 11th grade bio, and then an applied science elective in 12th grade: biotech, earth science, vertebrate zoology, etc etc.

[@CombustiveVideo]

This is an absolutely superb combination of art and science. An amazing skill and effort to represent something complex so clearly, eloquently, and most significantly, faithfully. Thank you!

[@WEHImovies]

Thank you so much 😀

[@TOKRocK84]

The Art comes from the creator. this is actually "just" good science, enabling us to see what is not visible (because of light, no'one's fault! :) and we like to look at it, of course!

[@TMtheScratcher]

Our cells are really basically some complex machines made of many "simple" machines. It is really interesting to see, that not all action on a molecular level comes from chemical reactions, but from mechanics as we know it from our macro world as well. Great animation!

[@RickyPollo]

I have to say, ATP synthase does not look like a simple machine to me!!

[@electricity2703]

@@RickyPollo Absolutely

[@bretth4988]

g o d bible truth

[@davidaugustofc2574]

Lies in the replies ​@@bretth4988

[@Gelatinocyte2]

@@RickyPollo really? It's basically like a turbine and generator. The top part being the generator, and the bottom part being the turbine with the flow of protons making it spin.

[@AlexMadinger]

Incredible animations - keep them coming!

[@NiMz849]

Drew Berry, thank you! There are not many videos of this kind on the internet. That makes your works so valuable.

[@TOKRocK84]

and he got 7 min on Ted xD

[@Gelatinocyte2]

@@TOKRocK84 the guy clearly didn't waste his time making his presentation longer than necessary; he kept it simple.

[@victorianunezbaron1536]

The animation, the explanation and the music...Biology is so fantastic, a masterpiece.

[@PasseScience]

This one gave me shivers (good choice of music).

[@dgk2m9]

Amazing! Crazy how the real life protein complex is rotating a hundred times a second, and there are trillions and trillions of these running in my body right now.

[@aslassin]

ABSOLUTELY FANTASTIC VIDEO. You have brought something that looks boring on paper and shown it in it's life trough an amazing animation. Thank you so much my test is in 2 days!!

[@luisfeliperomera8104]

This kind of quality and precision changes the image that we have of microscopical events in our mind. As a biology undergraduate, i am very thankfull for the animation, it really helps us understand the biomolecular world better

[@gus..611]

The best channel for animations on molecular biology ever!

[@TOKRocK84]

I sthere another one of this sort?? :)

[@claudiorassouli1240]

The best video on ATP synthesis. This is beautifully done in terms of animation to audio with narration.

[@gelatinocyte6270]

As soon as the video shows the inside of the mitochondrion, the quality settings went down to 240p. This video is high quality; that's what I love!

[@mrvzhao]

And the music... it's just awe inspiring.

[@BD-bditw]

Sorry to disagree, but the dreadful music ruins the whole presentation. What we are after in these types of uploads is information, clear and concise information, not some head- banging music which those who like such a thing can find plenty of here on KZbin. All the best documentaries do not drown out the speech with awful drumming and incompatible 'music'.

[@BD-bditw]

With all respect, most people surely watch these amazing uploads to see the scientific content and learn about these natural wonders, they are not here to listen to this dreadful background 'noise' as I call it. This upload is ruined by the so called music and masks the narration. Just look at all the great documentaries like Planet Earth, Walking with Dinosaurs, etc., the sound on which is suitable for the subject matter. Anyone seeking this dreadful kind of background sound can find plenty on KZbin without having to suffer it here. I hate to have to say it but it does seem to be far worse on US programmes.

[@TheHeartOfTheHour1]

@@BD-bditw You want all the scientific information but can't "behold!" any of it. And even this comment doesn't make sense to you as you seriously lack experience of life itself.

[@zefellowbud5970]

​@@BD-bditw like it or not experience and entertainment has a big effect on how we learn things. this makes these stuff stick to memory alot better than just leaving it bland. also i dont see how the music on this one is bad. it deafen the speech at all. and the sync of the music to the rhythm of the molecular motor is pretty neat as well. its mindset like that that makes science in itself hard for the general public to get into. why is there alot of wackjobs like flat earthers anti vaxers that reject science? its cause of stuff like this that try to make it as clinically un fun as humanly possible.

[@user-sz5slm]

Simulation like this helps to look at biochemical processes from a different point of view. An incredibly efficient and beautiful synthesis process! Great animations!

[@fearlesswee5036]

These animations are visually stunning and very great learning tools, but lets give props to the amazing sound design too!

[@ViceZone]

I love how the rotation of that thing is in sync with the music.

[@katbrown1449]

I LOVE THIS. I WNAT THIS DONE WITH CHEMISTYR TESTBOOKS TOO. MAYBE AM INTERWCTIVE GAME ? LETTING YOUNG PEOPLE MIX CHEMICALS AND WATCH THIS WAY??? THE TEACHING POTENTIAL..... INSTEA DOF REAIDNGA ND INAGINING ALL THIS... I M SO SO HAPPY TO SE EIT . ITS ABOUT TIME!! WELL DONE!!

[@rajaeazizi5830]

Such incredible videos make me wonder how hard your team is working to make them. Im so greatful, thank you.

[@DavidTJames-yq9dr]

Omfg. Please more! What is ur patreon account?! You are hereby ethically and academicly obligated to produce much more of this content.

[@2662Mia]

Okay maybe the edict about ethical and moral obligation is a bit much, but I do align with the author’s intent 😊

[@vinesthemonkey]

these videos are made by the WEHI organization. sponsor them

[@kiharapata]

I remember that back in school I had hadn't realized that ATP was part of the building blocks for DNA and RNA (just like GDP). With this in mind, plus the fact that ribosomes are mostly RNA, the RNA world hypothesis becomes almost obvious in hindsight -- RNA was the genes, the proteins and their means of energy exchange. It would be fascinating to discover that these tiny RNA creatures (if they could be called that) still live among us!

[@JohnDlugosz]

The "A" is also used by RNA and DNA, when connected to another large piece that's common to all 4 bases. Here, it has attached a chain if 3 phosphates (when charged) or 2 phosphates (when discharged).

[@gelatinocyte6270]

The ”A” in ATP is the same ”A” code/building block (A, C, G and T/U) in nucleic acids, I get it. There's also CTP, GTP and UTP which were also (rarely) used as source of energy.

[@spolo123]

Looks like life as we know it had to rely on a Swiss knife kind of chemistry, self unfolding. Makes actually lots of sense.

[@philsmith7398]

Brilliant! So many thanks for your hard work! It's easy to forget the dynamism when you're studying the pathways!

[@MrEzystreet]

This has to be one of the most amazing things you can see on YT!

[@BULLTRONHERO]

This music is nearly _exactly_ what I hear when I use DXM. My impression when I first started hearing it was that it was the chorus of countless microscopic entities (cells), the Song of Flourishing Life. That was seven years ago, and now, here I am, with exactly that playing out in this video before my very eyes. Incredible. What a profoundly, inexplicably beautiful world we live in.

[@markhaus]

These animations are so cool. Biochemistry is absolutely bonkers. But there’s something so creepy about how these molecules look when animated

[@isadorah4969]

It is so mesmerizing and scary to realize the molecules have no thought, just energy, and evolution made it into more and more complex and energetic favorable mechanisms omg

[@eki-eki-eki]

Fantastic! Such a powerful vibe.

[@supersonictumbleweed]

This answers the question of what would happen if you put a dynamo on each hole if a sieve or a strainer

[@kalkidanayele1886]

I am awed! Thank you for making this type of quality video available!

[@p33kin89]

Amazing. Before I began taking many science courses for my undergrad, I had a friend who told me that the human body was a messy, makeshift thing, randomly pieced together in order to function at the most basic level. I knew he was wrong then and I am glad to now be able to explain to him why he is so very wrong.

[@Apchenail]

I cried.. Nice soundtrack. I love how she repeats the sentences as if they were lyrics, or mantras, to be repeated as an hymn. "ATP drives biochemical activity inside your living cells, and is a key building block of DNA, and RNA"... "ATP drives biochemical activity inside your living cells, and is a key building block of DNA, and RNA"... "ATP drives biochemical activity inside your living cells, and is a key building block of DNA, and RNA".

[@gelatinocyte6270]

I love the addition of music in this video

[@RoverT65536]

I love these videos. I wonder what the time scale is.

[@dacsus]

it's in real time...

[@rickandelon9374]

it takes months(5-6) to create a final ready to ship animation of 10 minute length at this detail

[@LivingEpistles444]

This is actually in real time :) fascinating!

[@TOKRocK84]

Yea, Real-Time stuff, that'*s what makes it awesome! Try it as background videos of techno music... or any music... it's just ...cosmic!

[@Aexorzist]

@@dacsus It's not. ATP synthase rotates around ~100 per second in real cells.

[@kirbyvontraumland9447]

What a lovely animation about our organism's analogy to turbine and charging up batteries keep working on this brilliant animations

[@CellRus]

Can we just simply fucking appreaciate the beauty of this animation and the skills it takes to make such thing rather than entering a fucking debate about God and creationism, please? Why do people need to bring God into every fucking things that they can't comprehend?

[@regulate.artificer_g23.mdctlsk]

It's caveman brain, plain and simple. I feel you, so deeply. I don't understand why they feel the need to bring up their religion - and specifically over science stuff like this one. All I can honestly say is that it's probably some evangelization agenda.

[@SwanOnChips]

If you are so sure of yourself, explain how this process got started. Did you realize the creators of this failed to mention the cyclically dependent nature of ATP generation. ATP is required to manufacture the inputs to the molecular machine (ATP synthase) which manufactures the ATP. Maybe the reason this is conveniently left out here and everywhere is that it defies an evolutionary explanation. Oh, and 'it just happened' or 'it just evolved that way' is NOT an explanation. ✅ Actually, God did to it. That's why evolutionists conveniently leave out the full facts.

[@Gelatinocyte2]

@@SwanOnChips ATP occurs naturally in the universe. We don't know how, exactly, but they do. There are a bunch of proposed/hypothesized mechanisms on how they could form naturally, I suggest looking them up.

[@donross7820]

Beautiful graphics! Kudos to the creator

[@DepletedUrbranium]

which one?😇

[@nailyasadykova515]

Speechless! Thank you so much for your videos!

[@priyams7620]

Mind bogging awesome animated video ,tonnes of knowledge in just 2 mintues

[@millionsofsand]

absolutely love you for making this!

[@HibernonJunior]

Cheguei aqui por dica do @oatila. Obrigado Atila Iamarino. Por tudo.

[@richardhall5489]

beautiful work. I liked the audio too.

[@rochelimit55555]

I'm groovin with the ATP music

[@theconqueror_007]

These videos are far better than the sci-fi movies.....🔥🔥🔥🔥...just awesome 👍🏻👍🏻👍🏻👍🏻👍🏻

[@jamesascher8147]

beautiful animations. sadly youtube compression removes a lot of detail

[@thewssystem1471]

Who is the sound designer and/or composer of these animations? Edit it was within in the end

[@ericbrown2336]

Heaping glowing praise ! Top notch videos!

[@kevinc233]

I’ve learned this stuff years ago but it still amazes me when I watch media like this. It’s insane how much is going on in a cell simultaneously. This perfect little factories inside each cell. It’s amazing how with everything going on and flying around, things still function as they should. I’m sorry, but when I watch this, I have to think the purpose of the universe is to create life. Our cells are more complex than the processes in the universe. Although we are part of the universe, the macro universe is less complex than the micro. I have to think this universe was created with specific laws with the primary goal to allow complex life to form.

[@canrex7540]

Drew Barry you absolute madman!

[@kekero540]

People really have hundreds of superpowers all working together so we don’t collapse on the ground

[@SeaJay_Oceans]

Respect for the Brownian Motion that allows all of it to function . . .

[@joshpenn5473]

Excellent visualization!! Bravo 👏👏

[@MrShadedmoon]

Mind blown. Mezmirising and astonishing new learning.

[@supermememerch8872]

best animations I have ever seen

[@MolecularAnimationsoftheCell]

Drew Berry work is awesome, so accurate and perfect.

[@jakobweinzoedl3302]

Amazing simulation

[@MercifulArchitect]

I've rediscovered the meaning of having your mind blown... thank you 🤯

[@poojitha5273]

the video is at ultimate level... Lively feeling

[@yoursoulisforever]

Question: Would the molecular/subatomic process be so fast, as to appear a blur in real-time? Like a high revving motor?

[@regulate.artificer_g23.mdctlsk]

Yes, actually.

[@margueriteoreilly2168]

I absolutely love this Vt...the music sets the grounds for wild Wondering and Pondering......remembering why i absolutely love this channel....Belfast Ireland 🇮🇪 ❤❤❤❤❤❤❤❤❤❤❤❤❤❤❤❤❤❤❤❤❤❤❤❤

[@femto2]

Beautiful. Magnificently beautiful.

[@WEHImovies]

Thank you very much!

[@TheNasaDude]

The animation is fantastic, but the commentary is so succinct and simple that I don't feel like I've learned much. I think an hour long lecture could be made diving deep in this animation. How does the pump work? What are its parts? How do they interact? How is the pump made and how does it move to its intended spot? Why is there a difference in proton concentration?

[@WEHImovies]

More on Cell Respiration kzbin.info/aero/PL04jnTG4d1nZuxdfgL85V27NPjFTl025Y Free science education visit wehi.tv and biointeractive.org

[@SwanOnChips]

The creators of this failed to mention the cyclically dependent nature of ATP generation. ATP is required to manufacture the inputs to the molecular machine (ATP synthase) which manufactures the ATP. Maybe the reason this is conveniently left out here and everywhere is that it defies an evolutionary explanation. Oh, and 'it just happened' or 'it just evolved that way' is NOT an explanation. ✅

[@Chaos------]

These animations are a beautiful thing.

[@mohammad_mahdiii]

its more beautifull than what i imagined .

[@igordemelo4128]

my heart was synched to the beating. i am amazed!

[@absolutabsolem6494]

The most epic thing I've seen so far. A hell of a ride. 😅

[@hansmack6792]

I love the artistic value of your videos!

[@bokchoiman]

I wonder if we'll come up with a more efficient method of atp synthesis

[@vijayvaddi2282]

Are you shitting me? THIS IS THE BEST FUCKING SHIT EVER!!! I've been watching physics videos all my life but this blew my mind away to the next dimension. MOOOORRRRRRRRRREEEEEEEEEEEE!!!!!!!!!!!!!

[@williamwixon]

LOL! so true. It’s funny there are so many responses like this, WEHI knows they were blowing peoples minds.

[@MW-cx3sb]

Something to note is that ATP isn't the only way that the process can happen but it is the way life on earth has formed.

[@ytrew9717]

I wonder if one day we ll manage to engineer totally new machine made of such incredible nanomachine/mechanism. Evolution is so awesome.

[@aminulislam7823]

everything was amazing, but the music is the cherry on top. PEAK CINEMA

[@rebootukology1014]

This is amazing! Thank you.

[@marthamacias9332]

How the body work a lot to obtein the energy to made differents movements is so amazing, and watch by way of this animation is more easly to understand.

[@shinkano_]

Your videos rise my reverence for live!

[@eostre812]

Subscribing because I'm gearing up for food biochemistry course next semester!

[@landryprichard6778]

The motorized glory of it all. ❤️🔥

[@ShadeMeadows]

Our body is SO WEIRD. I LOVE IT.

[@SimonsAstronomy]

Thanks molecule ❤🎉

[@pietroscarpa2384]

Unbelievable that this is happening in our body's. It's a miracle.

[@SwanOnChips]

The creators of this failed to mention the cyclically dependent nature of ATP generation. ATP is required to manufacture the inputs to the molecular machine (ATP synthase) which manufactures the ATP. Maybe the reason this is conveniently left out here and everywhere is that it defies an evolutionary explanation. Oh, and 'it just happened' or 'it just evolved that way' is NOT an explanation. ✅

[@qwe123337]

these are awe inspiring

[@gugunovaes]

UAU, essa simulação ficou muito incrivel

[@shrik3090]

Are the software or the programs to show such animations available for download ? OpenSource ?

[@MrMikkyn]

Its kind of beautiful. We’re all a bunch of chemical robots with consciousness that arises from these tiny little chemical mechanism interactions. Its like all in some kind of weird complex mysterious order which we don’t fully understand yet, but that we do understand to only a partial extent. Only some of the knowledge to understand all these mysterious yet chemically determined interactions.

[@SwanOnChips]

Actually not. Neither chemistry or electronics can create consciousness. That's the spirit that is within humans.

[@ДмитроПрищепа-д3я]

@@SwanOnChips cool, where's your peer reviewed paper on proving said spirit exists and quantifying its effects? Oh, you don't have one? What a shame, guess we'll have to assume that spirits are still a fairy tale and have nothing to do with the real world.

[@hardik373]

this is so cinematic WOW

[@DepletedUrbranium]

Love how when you get to the deepest parts of science... instead of 1 creationist for every 20 evolutionists it's more like 50/50. Interesting trend. Continue on.

[@dima1353]

what ? Good luck finding creationists among microbiologists.

[@GuardianSoulkeeper]

Nope. Weird lie. Are you just hoping some gullible rubes will simply take your word for it?

[@DepletedUrbranium]

@@dima1353 the first man I ever met is both of those things, so I'm obviously biased against you :D

[@medicalbiochemistry_]

Beautiful and excellent work

[@aduxvemus6534]

Best channel on YT

[@fratermunky4336]

This is amazing, more please🙏🙏🙏🙏

[@feiipeballesteros2309]

muchas gracias

[@fawzibriedj4441]

This is very well done, thank you very much...

[@jimrutin]

What an awesome depiction! Thank you!

[@truthfulplanet8767]

the field of consciousness drives everything and creates electricity, amazing video... amazing. The scientific method will have to ponder that one forever

[@gelatinocyte6270]

The scientific method is what made this animation possible. There's nothing more for it to ponder and the animation represents all there is to know (to some extent) about the ATP synthase. Watching molecules do their thing is mesmerising.

[@shrik3090]

Consciousness is self Aware and it knew you would find this video and it showed you this video.

[@marahiperez4146]

This is now my favorite video

[@farhadzada3162]

The work is amazing. Thank you

[@zettelkastendev3760]

thank you mitochondria, thank you so so much.

[@josephgotto2572]

Drew Berry, more!!

[@JackQuark]

These amazing nano-machines.

[@SwanOnChips]

The creators of this failed to mention the cyclically dependent nature of ATP generation. ATP is required to manufacture the inputs to the molecular machine (ATP synthase) which manufactures the ATP. Maybe the reason this is conveniently left out here and everywhere is that it defies an evolutionary explanation. Oh, and 'it just happened' or 'it just evolved that way' is NOT an explanation. ✅