The Body After 2 Gallons Coffee In 3 Hours

[@HemeReview]

Subtitles on ✅!

[@rrezonkrasniqi]

He should have used modafinil!

[@SoumilSahu]

Sounds like Gordon Ramsay saying "Olive oil IN ✅!"

[@dosmastrify]

So what's a HEME?

[@mg8383ffdryhh]

Here's my, likely wrong, two cents. Insulin, glucose and potassium probably functioned to speed up the flow of potassium into the myocardium, quickly correcting decreased intracellular concentrations given her acidemia. I bet her heart would have gotten better over time as the leak channels slowly did their job, but the insulin euglycemic therapy sped up the process, which was important assuming low perfusion to her kidneys made it harder to correct her underlying acid-base status. BTW I really enjoy your videos. They're so entertaining.

[@gs-nq6mw]

Can you talk about aging and sleep?

[@DemonzSlayer49]

A doctor made 2 videos in one day. This is what happened to his viewers

[@wreckofthehesperas8323]

We are getting wickid smahht!

[@WangleLine]

lol

[@evelyntang9138]

I wish this guy was my professor for physiology in college. Life would be so much better

[@andrewcorbridge6350]

The guy talking or the guy who drank the coffee lmao

[@peetabread171]

Right! I may have gotten higher than a C in a&p 1 and 2 lol

[@taek_flyte]

I feel that's how most of my classes were, I would have learned so much more if things were taught through KZbin videos. Don't understand calculus? Here's a funny and informative KZbin video that teaches you better than I ever could.

[@UrielX1212]

@@taek_flyte Sad thing is of all the college professors I have ever had I could only count maybe 2 or 3 that were not completely worthless. Not many have the ability to actually teach the subject. Many are nothing more than overpaid regurgitators of the textbook.

[@WeatherHappens]

I'm incredibly humbled by the knowledge one must have to be a doctor.

[@Slavyach97]

Watches ChubbyEmu: This guy knows what he's talking about Watches Heme Review: Damn this guy really knows what he's talking about

[@DDE_ADDICT]

It's because he is a neurological toxicologist. he does consult his contemporaries in their specialties to refine the details.

[@blindsniper35]

It's always great when you get qualified people who can explain things in a way that most people can understand.

[@omba2362]

When you don't realize they're the same xd oof me too ;-;

[@nesfan8]

I think this guy knows much more than ChubbyEmu tho

[@OscarGeronimo]

Watches ChubbyEmu: I might have not heard what he's talking about Watches Heme Review: I definitely haven't heard what he's talking about

[@mikkejaksonen]

Damn, I can't even drink 1 gallon of water in the day.

[@xistencestudios8904]

@@reneekatz you could have multiple shots of espresso

[@xistencestudios8904]

@@reneekatz I guess that would happen. I personally rarely drink it so I wouldn't really know

[@TheEssJay]

Seriously lol at most you might drink a gallon of water in 3 hours if you’re dancing or playing basketball/some other type of high intensity sport for that long. But you’re losing fluid at very fast levels so you wouldn’t even notice drinking that much

[@benrosen3004]

KZbin challenge!

[@fernandomescalito5307]

Exercise and you will

[@salutoitoi]

I am not in medicine and don't understand it all, but the way you explain it, with the help of editing, make this very entertaining. Thank you

[@rakvian]

Same thing here, I like medicine and biology but I'm terrible at understanding and he still makes this very entertaining and informative as well, he's a great scientific disseminator IMO

[@dandan7884]

is it even legal to think about the word "mitochondria" without it being automatically followed by "the powerhuose of the cell"?

[@rsrt6910]

Most religions regard it as a sin.

[@mg8383ffdryhh]

Legend has it that this sin can be absolved by mentioning "battery" in the next sentence.

[@zungruitelbitladnaternoche7305]

Powerhouse of the cell? I'm thinking of AA? Right? But the power cell of the mitochondria is actually located in a tiny part of it called ATP... So .000000000AA?

[@Lennythewinner]

Yes, but you might need to go botanical and paraphrase it as "chloroplast... the manufacturer of the cell".

[@bmo14lax]

Is this a meme in the medical field? Because i definitely remember every textbook and teacher calling it the fucking " P O W E R H O U S E O F T H E C E L L "

[@lindseydejesus1877]

this channel is so easy to binge watch omg i could listen to these for hours (with periodic breaks to prevent blood clots in my legs, of course)

[@Ice_type]

Easy lay down while watching

[@thathologuy8299]

@@Ice_type gravity will make your bones and muscles basically shrink.

[@RainbowFlowerCrow]

@@Ice_type laid down and binge-watched Chubby Emu's videos. This is what happened to his muscles.

[@ellenorbjornsdottir1166]

I stand up most of the time.

[@DemonzSlayer49]

@@thathologuy8299 maybe that’s why I’m so short! Damn me being lazy. Not gonna quit tho, as I can’t get COVID this way, so technically in my terms, I’m being healthy.

[@helluhpinoy]

Caffeine be like: "Yo, GABA GABA!"

[@TheHumility101]

haha!

[@iwantmyfriescrispynotburnt3981]

Coco melon

[@samiraperi467]

*oontzoontzoontz*

[@MultiFandom8isFate]

HAHAHAHAHAHA!

[@melwasnevergivenaname]

This is the singular time I've seen the translation used as a joke, good job 👏

[@BrettonFerguson]

I guarantee the doctors thought he did cocaine or meth, maybe adderall, even after he told them he drank gallons of coffee. They thought "Yeah right coffee" and did the drug test on him. In their defense they would have been correct 99% of the time.

[@CJ-xw4tl]

It’s perfectly believable to hospital workers for someone to go to the emergency room because it has caffeine. Someone I know had a similar problem and it caused them to start having attacks and their heart was overworked.

[@nazirulhaqim4612]

Yeah. 99% of young patients I saw coming to ER with such presentation were due to caffeine overdose.

[@jhoughjr1]

nope. Caffeine will jack you up. 1 pill is not 1 cup of coffee. They did a tox screen id imagine as standard.

[@masacatior]

Imagine calling the cops 🤣

[@cheddargoldfishcrakers4591]

I often feel the compulsion to take notes when I watch your videos haha

[@justin487322]

Considering he’s plagiarizing, I wouldn’t take notes. ChubbyEmu Is the real KZbin channel

[@amybaron8285]

@@justin487322 made by the same person, but different levels of information and details.

[@lalunaruna5769]

@@justin487322 they are.... the.. same person...

[@sawc.ma.bals.]

@@justin487322 what? Dude hes the same person

[@Kianiofo]

Love that you made this, cause im a heavy coffee drinker sometimes, this isnt just educational it a major warning for those like many who LOVE coffee

[@paulstelian97]

Of course it was two gallons in 3 hours. That's highly unusual intake.

[@MrCmon113]

If you love coffee, you probably don't chug it so fast and in such quantities that it becomes dangerous.

[@Jack-Surreal_Panes]

I drink a lot of coffee. Think it also has to do with how much and how long one has been drinking it. Some people drink a pot or 2 monsters and nothing. Others have a cup of coffee or tea and all over the place.

[@Billy_bSLAYER]

@@Jack-Surreal_Panes Today is Day 2 with no coffee/caffeine. Recently, the Venti Starbucks getting downed in combination of wearing a mask (yes, I know) while working in public places (network engineer) was giving me super anxiety. Also, I may have been drinking enough throughout the day and night to where the caffeine and other molecules never had a chance to stop fucking with me. This morning I felt awesome, more alert and clear than I ever was with coffee.

[@mistylongo8403]

I agree thank you! After a botched gastric bypass and abdominoplasty and 360° cut and corset cut to remove my apron. They did them a year apart but they did them backwards (the plastic surgery first). For the first two years after I could only still tolerate a liquid diet and I then turned to coffee as I realized at that point something was wrong because I was physically unable to eat even purées or baby food. I was drinking four extra large hot coffees each with two turbo shots at a minimum in a day. I had no idea what it could do. Thanks Doc!

[@JodyBruchon]

I like messing with people by telling them I do the drug 1,3,7-trimethylxanthine. When I tell them what it is, I usually get a minor snork, and that's good enough for me.

[@GuadoGirlX]

Caffeine?

[@JodyBruchon]

@@GuadoGirlX yes.

[@mistylongo8403]

Lol 😂

[@Franglaiso]

I tell them I do heroin.

[@neoschizo]

This was so interesting! I didn't even know half of that.

[@KvatchIsInDanger]

I didn’t even understand half of that!

[@zungruitelbitladnaternoche7305]

I sure learned a lot, but didn't "really" understand 10% of it. I just got a good imagery of the molecular mechanics of it. I don't think this channel is meant for layman but I still enjoyed it.

[@RamseySchaefer]

I didn’t know any of it

[@hyperfruit541]

I didn't understand anything!

[@Firecrackercam]

This was stolen from a channel called chubby emu

[@deyjaacterius9610]

First heme review episode I’ve seen, and I love the academic focus! I definitely want to suggest something like an end card on the main video with VO saying something like “click here to continue this video on my second channel, the Heme Review Podcast”. I know it would disrupt the normal end we know and love, and I wouldn’t know whether to put it before or after “Thank you for watching. Take care of yourself, and be well.” but sometimes all it takes to drive engagement is put something you know they want to see right in front of their face and tell them it’s more of what they’re there for already. Sorry for the rant-thank you very much Dr. Bernard for your work in education and in the medical field, we love you!

[@altheaunertl]

I don't think I've ever heard of high dose insulin therapy like this. I had to rewind when you first said the units/ kg because I wasn't sure I heard that right. And the continued high doses given hourly was also more than I expected. Very informative cast, so thank you!

[@manwellO7]

Watching this after the chubby emu video really shows how much you put into the video and how much is cut. This makes the first video even more interesting for me. You have a very great skill of relaying information and making me feel like I’m learning something. I don’t know what I’m learning but I feel like I am learning.

[@Michael-zg1oh]

I specifically have experienced accidental beta blockade/ unopposed alpha stimulation. I was transitioning off propranolol and on to Catapres. Even understanding the short half life of the beta blocker was not enough to prevent the accidental syndrome. After about 10-15 min of taking the Catapres, my head felt like it was in a vise. I took my blood pressure and it was 183/130ish. I do not recommend this. It took about 15 minutes too come down into the 160/110 region which made me feel better about my chances of stroke. Catapres carries a warning about initial blood pressure spikes that were made worse by beta blockade. I did not continue the medication. Excellent podcast.

[@HemeReview]

Thanks for sharing!! Glad you’re ok now

[@IriaTHaze]

Tell us more about GABA. The more research I do on certain stuff, the more I feel a need to understand what it does and how it interacts with other neurotransmitters.

[@Alethiometer]

As usual, the case was utterly fascinating packed full of vital information medical terminology, I just love learning new stuff & the amount of knowledge packed in this episode was especially important as I have been known to abuse caffeine on occasion, & I'm ashamed to admit to my ignorance as I have said many times "No ones has ever died from drinking coffee, it's safer for you than energy drinks" Yikes! It was so informative & fascinating I watched it twice, okay okay I LIED I watched it twice because I had too much coffee & can't sleep NOT KIDDING

[@tramtruong7433]

*mitochondria is the powerhouse of the cell* I said this to my bio teacher when he asked what's a mitochondria. There was no reaction 😔

[@patrickdemenezes4204]

lol

[@andreagriffiths3512]

😩 how disappointing!

[@loki_cane_corso_italiano7825]

I wonder why i don't get a reaction from my coffee. I drink coffee and then go to bed, fall right asleep. I've seen people drink coffee and act like they are really wired! Why when i drink coffee, even exhausted, it doesn't do anything

[@HemeReview]

It may be the coffee and/or it may be you! Some people are very fast metabolizers of it, while some are very slow!

[@SlimThrull]

NOT a doctor and I have no scientific evidence for the following, so take it with a very large grain of salt. I have a friend who actually gets sleepy after drinking anything with caffeine in it. It's REALLY bizarre to see. Even after one cup of coffee she just kind of dozes off.

[@dragonrer]

SlimThrull This happens to me as well hopefully this channel can bring some insight to that!

[@SujalRajput10]

Same with me

[@TrollHiddenCave]

That means you have ADHD

[@happyundertaker6255]

I still think that Sympathomimetic toxidrome sounds like a really cool nightclub.

[@indoloreveritas]

Reposting here for visibility: As someone who ingested roughly half of BB's dosage (1600 mg) in a similar timeframe (2 hours), may I add the interesting symptom of feeling as though my skin was bunching up into my fingertips? I am proud to say I was able to help troubleshoot my professor's issues with Mathematica in between trips to the bathroom to dry heave into the urinals. Physiological question: the agony was over after 9 hours at which point I enjoyed 12 hours of dreamless sleep The next morning I woke up with a sense of euphoria so profound I walked 3 miles to school and felt great the entirety of the day. Was this just a relative subjective state or was something else going on in my headbones?

[@DasPlayer2]

I experienced a serious bout of hyperkalemia and hyperglycemia from ingesting a wild amount of vitamin fortified orange juice, on top of a weird mystery medical condition that causes me to bleed into my abdominal cavity, causing swelling across my body. In short, it was 14 hours of completely manual breathing and fighting to not pass out, since I would immediately fall into respiratory depression and after two bouts of that, knew that I might not survive more, or accumulate too much brain damage to function. After 14 hours of this, which I can best describe as hellish, I had the same feelings of near euphoria over the smallest and simplest of things, silently crying my eyes out in happiness to any heartfelt song or telling my friends how much they mean to me. It lasted for a day but went away after-so to answer your question, I think it was a subjective state, but I am not a doctor, so I can only rely my experiences.

[@matthewwynn3025]

Interesting, I would say that it was probably more of a "minor" tactile hallucination. Other stimulants in high doses are known to cause "crawling sensations on the skin". Back when I was a kid I took Ritalin and that stuff would make my skin crawl, and other weird skin sensations like tightness

[@wongelfski4681]

You may be in a hallucenation

[@Chris-xs3vu]

I had a headache for 2 weeks after cutting down completely on coffee after drinking it for 3 months daily

[@DemonzSlayer49]

On the last video, he said roughly 1-2 cups of coffee doesnt do much harm. As for your dose, you injested roughly that. For your euphoria, I dont know how the hell you got that. The symptom you are talking about is either tingling, or twitching, or just feeling heavy hands. There is not something else happening in ur headbones.

[@miguelrodriguez1750]

Thanks for putting subtitles on your videos. I wear hearing aids.

[@CaedusDeorum]

Same!!

[@Therealgigabyte]

I am really glad you do a more serious review of cases. Both your OG channel and this new one are good. Keep up the excellent work!

[@omgurheadsgone]

Please upload more videos on this account! Or Damn, upload them on the main channel so they get the views they deserve. These are so incredibly in-depth and educational, I love it. I thought the main channel was interesting but the depth you dive into the medicine and sicknesses on this channel is just fascinating!

[@jcrc1]

I think he's said he wants to keep this channel separate so he can talk about the cases in a more technical way than on his main channel

[@zeromailss]

2:58 "More study time meant a better chance of scoring higher in the exam" As a graduate, I can assure you that this is the worst idea ever, don't do it. Work smarter, not harder. Research the test, the professor habit, and history, ask senior and friends and focus your study to maximize the chance of a higher score (if that is what you want/need, I prefer learning to understand not just memorization of question and answer but there's a time when the score is the priority) Lack of sleep leads to terrible memory hence wasting time and effort. Resting well, and choosing the right time to study is key on top of studying the right thing, this way you can get double the result with half the effort.

[@AMAZINGBEAST6]

Having just finished my first year of medical school, I’m in awe. Please keep these case study videos coming! :)

[@onesummerday9716]

I remember trying to pull an all-nighter by binging on caffeine, about 3x my usual intake. My heart beat as if trying to jump out of my chest, curled up on the floor and thought it was gonna be the end of me. Though damn BB got it way worse

[@griffinguzaitis4572]

A man drank [x] gallons of *Insert substance here*. This is what happened to his [Heart/Brain/Liver/Kidneys/Pride]

[@saikrithiks2870]

Also sometimes, "A man had (had/seen/touched/owned) a (insert a domestic animal/insect) This is what happened to his body"

[@davr1]

At least he's not clickbaiting

[@tylern6420]

A man drank 999 gallons of Natas fluid. This is what happened to Natas.

[@mineown1861]

Friend of mine did an all nighter for one of his engineering finals, took caffeine tablets . Just before the exam, he felt a little tired , so he had a cup of coffee just to get him through . His hands started shaking so much he had to write in 1 inch tall letters to approach something legible , passed the exam but went through a hell of a lot of paper to do it .

[@renkomon.8312]

16x the amount of caffeine is insane! while I understand that the guy was pulling an all nighter, that was over kill. I feel bad for his mom that had to take him to the hospital.

[@davebellamy4867]

11:42. Le Chatelier's Principle! Wow I haven't heard someone else say that since A level chemistry in 1983-1984. I thought it was one of coolest phenomena In chemistry and it kind of applies to some physical processes too.

[@lrwerewolf]

I still don't know how I survived drinking 5 gallons of turkish coffee in less than two hours. When I ran the numbers and realized I'd exceeded the LD50, I was REALLY glad I'm a, as airlines put it, "a gentleman of size." >.< It was nearly three days before I could even manage to attempt to sleep, and four days before I was able to get a significant amount of rest.

[@nugboy420]

0:19 I like the smirk as if he knows sht’s about to go down.

[@loganmunoz7720]

I’m just a high school student but I’m trying to study this on my own. My aunt is a nurse practitioner and I find psychiatry very interesting so I might try to learn both. When I have to study hard I won’t drink 2 gallons of caffeine lol. I watch all your videos btw and I pick up a lot. I’m glad heme review is a thing so I can learn more now. I’m really glad you make videos and want to say thanks for posting these things Dr. Bernard :).

[@dylonbland]

Caffeine be like "Let's make people think they 'bout to fight".

[@RainbowFlowerCrow]

Lol, heartbeat go brrrr

[@MysteriousFuture]

Many people are “fighting” to survive working multiple jobs and gotta stay awake 😂😂😂

[@eryalmario5299]

This channel made concepts in medicine more easier to digest than in nursing school

[@Nellinator23]

I'm a recent chemistry graduate and I generally enjoyed organic chem and biochem more than my other courses. This kind of detail is fantastic and I absolutely love it, even if I still don't fully understand some parts of it. Thank you for going more into greater detail on this channel; I'm definitely going to be keeping up with it!

[@RHill79]

A man clicked a link to a channel recommendation, this is what happened to his afternoon.

[@carabradford6464]

As a nursing student I really enjoy your channel and listen to it for fun

[@AndyDurandal]

My brain did a weird back flip when you said "With anything that is a chemical be careful" because I always think "water is a chemical" when someone talks about chemicals broadly. This was immediately followed by the "tube of clean water in the bowl of salt water" experiment replaying in my head.

[@ethandewicki576]

I really enjoy the medical explanations, because a programmer, I see tons of similarities in how a computer uses variables to trigger and perform various functions and how your body uses neurotransmitters, ion channels, and hormones to produce physiological and mental effects. For example, adrenaline signaling the release of 10,000 other molecules. GABA and Glutamate are so much like bits in a computer which serve as the main on/off signals (0 is off and 1 is on vs GABA is inhibitory and Glutamate is exitatory). The more I learn about how the body works, the more similarities I see between us and the complex machines we use. Cool stuff! Thanks for all the great, mind expanding content! I think even non-medical people like myself can really benefit from learning these things.

[@katieluv8422]

I have always said that these processes are just systems with inputs, actions and outputs. If we can memorize complex computer systems, we can memorize biological systems as well.

[@Sooners84Gaming]

I was watching the other video and saw this, I thought someone just ripped your video lol, keep up the amazing videos man

[@ceciliavis7556]

i love this new channel, im always here for new content by you🥺 i have so much respect for u and the way u explain things like this so easily 🥺🥰

[@kingstaa123]

I know nothing about medicine but always wanted to learn about it but never could I get my head around it, this guy makes it really easy to understand and the way he explains why different things happen is really interesting !!! Just so easy to follow n really interesting at the same time!

[@tdtrecordsmusic]

Man, I love this level of detail. SOOO happy I clicked !!

[@krthk456]

Love it, all the premed stuff I have been absorbing for the past 3 years, finally makes sense.

[@theoldbore6835]

this channel is much more my jam. I know I am late to the party and all, but this feels a lot more my speed

[@garybulin357]

Thank you for taking the time to create these high quality, informationally dense videos. You rock!

[@carolg964]

You are nothing short of a genius my friend. Good health and long life to you.❤️❤️❤️

[@CTimmerman]

I pull all nighters by accident when i'm focused on a task and snacked too late.

[@brainzend]

I have loved your ChubbyEmu channel for a long time now and I really love that you decided to take Chubby farther with this Heme Review. I am always looking for practical application physiology but most sources are attempting to clarify simply biology or they are encrypted and hidden in the bowels of crusty texts which make it as easy to consume as the legalese in your EULA. This is exactly in the bullseye for what I am looking for. Rhonda Patrick's Found my Fitness podcast has been getting me by but, while fascinating too, she is mostly focused on longevity research. Your use of animations and visuals makes this even more digestible. Thank you very much for what you do.

[@zkiphier622]

There should be a law or policy to allow study to get enough rest and learn over a "reasonable amount of time." Could help reduce the suicide rate in medical students.

[@Sonyboj]

Very good video, thank you. Not in medicine at all but the fact that our bodies can take so much damage and recover... with help ofc but still.

[@12q8]

Your second channel is also amazing. Try maybe reminding viewers it exists and you upload new videos by the end of every episode on the main channel.

[@jedimaster91]

I do nuclear stress tests so I’m veeeeeeeery familiar with caffeine’s affinity for adenosine receptors. People’s morning coffee is the bane of my existence sometimes. Fun fact: even decaf tea and coffee have some caffeine still. So does chocolate.

[@sravanbendi8012]

You are really awesome and I am personally a big fan of you and your heme review is very informative than your main channel and definitely deserve a lot more subs please continue the heme review channel

[@lialaie2214]

For the most part...I didn't understand 80% what you were saying but was still glued to watching lol

[@ravennr97]

Man I wish I had this video when I was taking biochemistry. It makes so much more sense when applied to a real life example.

[@debstherottie472]

You remind me of Dr House without all the snark! :) Great video as always!

[@snorkfyren]

how are you even able to drink that much of anything. wouldn't you at some point just puke because your stomach is full??? hooww?? if 2 gallons is about 7.5 litres it's just a wild amount of anything

[@Skiskiski]

I used to drink up to 7 cups of coffee a day. One day my late (wife's) daughter challenged me to get high: I drunk 7 cups of coffee at a buffet in 1 hour. I was high! Just from caffeine. On our way back home, I had to pull over because I could not drive. it took me two hours to be able to get back into the car and drive safely.

[@PaigeLovelace]

In the last week alone I've had 11 pots of coffee

[@purplefn3587]

The bit about the insulin euglycemic therapy and the fact you noticed a line in it contraindicated another researches therapy....brilliant 👏

[@dfbess]

Is this a new channel? I watch Chubby Emu Everytime you post.

[@HemeReview]

Yes, it’s a podcast where I try to talk a little more in depth than Chubbyemu videos

[@exidy-yt]

@@HemeReview I hope you are able to continue because this was even more interesting then the source Chubbyemu vid!

[@Seth-mu3wo]

When I was in the 9th grade, a boy in my gym class took an entire bottle of caffeine tablets at lunch (100 tabs of 200mg each). Nobody knew this at the time, but came out later. He was running about 5 feet in front of me on the track, when he collapsed. I was there within 5 seconds, and began to do CPR within 30 seconds. It was no use, because he was dead before he hit the ground. He had massive heart failure,; it just exploded in his chest. Abusing any drug is no joke, even if it is legal.

[@redbirddeerjazz]

Sorry you went through that, it must have been traumatic.

[@worldview2888]

Love and cheers to this channel and video. Don't forget the limit is 1.5 gallons guys. **EDIT** OK - EVEN AS A COFFEE LOVER. I guess 1 gallon would have been more than enough!! I drank that amount during one of my most stressful days at work (and because the coffee machine was free) and i felt VERY SHAKY after that.

[@JodyBruchon]

👏 👏 Heme Review is my new podcast where I put you through medical school for free.

[@JamesKelly89]

When I was younger I used to drink something like 12 cups of coffee a day and I'd get muscle twitches and flashes in my vision that looked like lightening. My doctor told me to cut back on my caffeine intake. That said this video explains a lot to me about what was going on.

[@BeatsByZ3P0]

Always opt for espresso. It has more useful dissolved solids and less caffeine (a water-soluble chemical) by weight

[@reneliue]

Chubby emu is like Dr house but real and explains the thought

[@Seelensocke]

You know, your shift from making gaming videos to life videos to life improvement videos, finally arriving at toxicology, is a great change indeed. But when I compare this content to your earlier content, I can say with confidence: As much as I would love to see you finish the Soulsborne games, the medical content is what you should be doing. I feel that your star shines the brightest whenever two capital letters present to the emergency room and you're there to explain.

[@golden3008]

Maybe after having 90 minutes of seizures and a heart rate in the upper 180s her cells needed energy. I mean she was running a marathon basically and the insulin + dextrose helped get that energy into her cells. Idk I'm not a doctor, but thoughts?

[@pitzahoot4618]

I was about to google the galon to liter convertion until I saw the description. Thanks.

[@katieluv8422]

I definitely like this medical professional oriented version than the ChubbyEmu version.

[@Ivy20242]

How does someone drink 7+ L of coffee ????

[@princetamrac1180]

Thanks for the description

[@n3k0rrrb]

Anyone else just a regular folk with a GED but this is super interesting and you can't stop watching? Like a hospital show with all the science and none of the bad writing :3

[@chuckdaddyfanfics]

A few years ago, I made myself tremble, have slightly paranoid thoughts, and vomit uncontrollably for the better part of a day by taking too many caffeine pills. And the amount I took was "only" 1.2 grams. Watching this video made me realize I probably dodged a bullet; I can't even imagine how it must have felt to have ingested 7 grams. I'm much more responsible with my caffeine use these days, needless to say.

[@singularity___]

There's some real meme potential at 3:19

[@deadgiveaway-z3i]

I quit caffeinated-coffee because of anxiety, i constantly felt as if i was going to drop dead any second, thanks caffeine.

[@mychannel-lp9iq]

Ughh caffeine OD is the worst feeling ever

[@andrazfrice8599]

I just found your chanel. Hafe of the stuff you we're presenting and explaining I did not cath on do to my lack of medical knowled. Overal it did inform me more about the sience of caffeine. Keep up the up the informative work😄✌🏻

[@TheMrDrMs]

This guy. Er should I say doctor!? Genius, went from student in HS from his first posted videos 10+ years ago, thru MD, and found a solid way to study his material (even if it was only a portion of what he had to learn), share it, and possibly earned a few bucks along the way. Kudos to him! How does he have time to accomplish all this? I feel like such a slacker...

[@zacharytaylor190]

The LD50 for caffeine is approximately 370mg/kg. For a 70kg adult, this amounts to 26 grams of caffeine. This is not to say that 7 grams is safe, quite to the contrary. It can definitely case bodily harm, and is very dangerous. Nothing like when a university accidentally gave volunteers 30g of caffeine in an experiment though. Quite luckily, everyone survived with specific retrograde amnesia.

[@blindsniper35]

Very interesting I hope you keep doing these more in depth explanations. I've always been fascinated by how chemicals interact in the body and caused their effects. Thank you for teaching me something new today.

[@kummdogmillionaire]

Hey Bernard, @8:27 you mentioned that caffeine toxicity from epinephrine causes hypotension because of beta agonism. I’m aware epinephrine decreases peripheral resistance, but I think it is more so due to the alpha 2 agonism inhibiting the baroreflex and CNS. B1 agonism does increases heart rate and cardiac output, but also secretes renin from the kidney to increase blood pressure. Regardless, these videos get me hyped.

[@HemeReview]

Beta agonism also causes vasodilation, as well as bronchodilation (albuterol), so which one’s which?? 😲 easy question to trip up students 😉

[@kummdogmillionaire]

Heme Review Podcast thanks for the correction! You’re totally right. It is the beta 2 agonism mainly causing vasodilation. Gotta brush up on my autonomics.

[@mellorides3379]

Could you do a video on how and why stimulants affect ADHD differently?

[@shivz732]

I'm just happy that I came across this video. When I was in collage I did something similar, drank 5 or 6 cups to stay awake. I was shaking in the end. Nothing happened tho. I guess I was just lucky enough. The pressure schools put on you is stupidly high.

[@patrickdemenezes4204]

i love your heme content please make more

[@CompanyBusinessCards]

Brilliant as always

[@sunkcostfallacy2738]

I once drank an entire pot of coffee before going to work. Nothing bad happened physiologically, but I'm glad I have this information now. I was just hyper-stimulated and probably looked like I was tweaking or something. Someone asked me what was wrong, and I just said I had an entire pot of coffee. Not one of my best decisions, but I'm glad I didn't seize out.

[@skycaptain95]

He might have almost killed himself, but at least it had water in it so he was staying hydrated!

[@WillN2Go1]

It's very easy to (moderately) overdose on caffeine. I don't mean end up in the hospital; just significantly spike your normal caffeine dosage. This happened to me while traveling. I'd order an Americano, 3-4 shots of espresso. At home I drank a pot of drip coffee. Some days I drank a second Americano. To cut back, instead of a Large (grande or whatever they call them) I'd get a medium. Maybe I didn't hear this correctly but the barista said it was same amount of espresso, just less water. (Is this true? Happy these guys aren't selling heroin). One afternoon after a couple of days of sorting this all out I'm pretty sure I experienced a posterior vitreous detachment. I thought I was starting to hallucinate or have a stroke. Then I googled my symptoms. After that I switched to the drip coffee from the shops (which is also higher than what I was drinking at home, but I drank less of it.)

[@LeighPhillips78]

everyone who loves these videos...give (some) medical academic journals a try! I have an arts background, but have some rare diseases like Klippel-Trenaunay Syndrome among other blood disorders. I have read everything. Though I WISH Dr. Bernard was my doctor, my primary care doctor probably would have killed me by now if I didn't have a specialist---one in NYC, and I try to be my own scholar of the vascular system. The deeper you go, the more there is to learn and love about the human body's fragile ecosystem. Why wouldn't you want to learn everything about that which keeps us alive? But I can't imagine life without this channel and Heme Review's "The Future of Medicine" is brilliant.

[@quentingivens4]

Just dropped in to salute a fallen demigod. When I managed a cafe I peaked at 18 cups of coffee per day, and it warped reality in my chest cavity, so I can't imagine what getting a full 2 gallons in less than half that time must have felt like

[@sooweeq123]

Love these vids. Great gem of a vlog

[@austindavis4708]

I nearly had a medical emergency because of caffeine misuse. I had a severe panic attack influenced by multiple different factors including excessive caffeine use (400+ mg per day), low potassium, combination with adderall, lack of sleep, and unusually high stress at work. I remember feeling lightheaded and my vision started going dark so I sat down. I didn’t realize at the time that I was hyperventilating. My supervisor saw me pale and hyperventilating and eventually 911 was called. By the time the paramedics had arrived all my muscles had started cramping because I had over saturated my blood with oxygen. In the emergency room they put me on a potassium IV and ran some other tests. I’m thankful that the people around me were able to get me help before I did permanent damage to myself. Things could’ve gone so much worse.

[@ashukalia6195]

thank god! I found this channel ❤️👌🏼