The end of genetic disease | Jacob Corn | TEDxBerkeley

What if humans could be edited to run faster, jump higher, and think bigger? What if disease could be eradicated before it ever came to be? These are the questions that no longer belong in just comic books, but in the laboratory of the Innovative Genomics Institute’s Scientific Director, Jacob Corn. In this talk, he explores the future and ethics of CRISPR/Cas-9 genome editing.
[AV and event video provided by repertoireproductions.com].
Jacob Corn is the Managing Director and Scientific Director of the Innovative Genomics Initiative and faculty at UC Berkeley in the department of Molecular & Cell Biology. Jacob’s research generally bridges reductionist mechanism with cell biology, with the overarching goal of understanding how biophysical properties interact within the cellular environment to shape signaling behavior and how disease arises when these properties go awry. As the director of the IGI, Jacob is committed to pushing the boundaries of next-generation genome editing for transformative insights into fundamental biologies and to laying the groundwork for clinical and commercial applications of the technology.
This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at ted.com/tedx

[@snehasisdutta3406]

He explained the whole basic things in a very lucid way...Expecting more videos and more deep concept in future.

[@markpeterson1837]

This genetic editing is truly amazing and a great break through in modern medicine. There may be some back lash with the idea of the treatment like being God from editing a person's chemical make up, but the diseases that can be cured will help hundreds of thousands of people if not more. Corn mentioned the expanse of things that genetic editing can attribute to, but what is the full extent of the changes that genetic editing can do for a person and how many health fields can this new technology impact. I think that genetic editing can go beyond just genetic diseases and possibly finding a way to re-engineer viruses to fight other diseases. What makes me question the editing is what if they replace the wrong gene and cause more health problem as an effect. There needs to be a lot more testing but as the future draws near and genetic editing is perfected, this will become one of the biggest breakthrough in medicine since vaccines.

[@hitoyoshizofa]

I sure do hope they proceed fast and well with this technology too. It can do wonders for people living with constant pain or other debilitating diseases and that too all purely because they were born unlucky. It can offer a normal life for those people who have had nothing but pain and sickness all their lives. And about the God stuff, I too am christian and have grown up in a christian community but I don't feel this is about going against god or anything or being our own 'gods'. If it can give relief to people who have been in pain all their lives then go for it. They say god works in any and all mysterious ways so why not through the works and advancements made by our own fellow human beings as well.

[@jjk2one]

You are not being told the whole story and they know you will not even look.

[@ManishKumar-xx7ny]

We started this journey of becoming God a long time ago.

[@rajurockss]

Is there any treatment for CAH my one month old son is diagnosed with CAH

[@ManishKumar-xx7ny]

Welcome to the Future

[@ExhaustedPenguin]

Very nicely explained and paced.

[@arash4712]

Very interesting

[@Vinkush2]

Sir , please help me, my child 8 years age , till now she is not able to recognise the parents, not able to talk , not able to go urinals of her own. Doctors are saying there is no medicine for this . Please help me to find any soln.

[@hipfire1920]

I am so sorry

[@biswaranjansahoo34030]

What about hereditary spherocytosis, it can be cure?

[@Gobberfisch]

So CAS9 is like crtl + F for us computer science guys? awesome!

[@demetronix]

not really. It is more like sequencing is ctrl+F, Cas9 is ctrl+X and homologous directed repair (and a piece of DNA you want to insert) is ctrl+V. All these technologies are applied in these types of experiments.

[@geckoyacht]

You don’t need to be a computer scientist to know keyboard shortcuts lmao

[@varshabajaj9]

I am from India how we get casper cas9 please tell me my son suffer from dmd

[@SupernalOne]

it's not ready yet, it's only in the developmental stages - very sorry; but keep watching out, China may solve the problem first.

[@edreyes894]

Berkley is in a patent battle over tech our tax dollars funded. Greed will destroy or control the direction of this tech also. Thanks for the content.

[@kirankarpe31]

I am suffering from duchene muscular dystrophy is there any cur3

[@andypuns151]

Yes there is! I forgot the name but they are still testing the drug out.

[@cutekuddi9125]

​@@andypuns151 plz lemme know

[@kailuaelbub2689]

There’s treatment for icthyosis???please answer me😢😢😢😢

[@opcom64]

try spend 10 minutes under sunlight after 4pm..

[@kirankarpe31]

I am sanchit akhade suffering from duchene muscular dystrophy can it be cured

[@hugomiller7087]

HELLO SANCHIT I HAVE THE CURE, GVE ME YOUR 13 GOATS AND WILL EMAIL THE CURE TO YOU

[@alikhokan786]

Hugo Miller Are u dr.

[@christosantonopoulos2018]

maybe talk about companies asking professional benevolent scientists in military intelligence before implementing things or new ideas and invensions in life.

[@antoniomartin5417]

GENE EDITING 35000 VIEWS START WITH WHY 26 MILLION WTF?

[@sudipaich7617]

Any treatment of genetic dark circles 😭😭😭

[@vaccinefraud5570]

You can make a surgical cut and paste of a particular gene to 'edit' it. Pay no attention to the 100 mutations that it made downstream of the target.

[@higreentj]

We need to remove all these identified damaging mutations within our species.

[@howmathematicianscreatemat9226]

Tj Green ; do you think we could remove autism and Down syndrome with it too?

[@kobki66]

@@howmathematicianscreatemat9226 of course!! i'm wondering why it isn't happening right now?

[@howmathematicianscreatemat9226]

@@kobki66 ; really confident? :O but how? Do we know the exact genes and is it really generaliseable to other humans?

[@zerothehero123]

I really want my mthfr and serotonin receptor genes changed! Everyone in the world needs free acces to a better genome. No more mediating symptoms! No more depression! No more suffering caused by suboptimal health!

[@ArcticZombie]

@@howmathematicianscreatemat9226 Maybe in a few decades we'll be able to remove certain genetic diseases. We might even be able to prevent cancer.

[@dragonore2009]

Wow great, this is good news, now all we have to do is wait 50 years for FDA approval. Don't you just love government?

[@whiskey4930]

love how they mention only the good parts. no what if x went wrong and now the patient doesnt have essential bodily functions and dies horribly. but still amazing technology i cant wait to see what advances we see soon

[@dayanandshinde8832]

Please Hailey Hailey diseases for information

[@snowy9764]

Jacob Corn... I hate the Cro-Magnons about how they treat Neanderthals today..

[@opcom64]

we don't fix the causes of these defects instead learning to engineer it out from another defective mind... is that how scientifically we decide to evolve? I learnt the hard lesson from my son, he has a genetic condition - the problem is not him (at all!), it it guy like me or Jacob Corn telling that they are the problem to be fixed. I learn allot from my son about our life, he is changing our life for good. You want to fix him?

[@ManishKumar-xx7ny]

you are selfish

[@vaccinefraud5570]

Attached and detached earlobes??!! like the two different actors that play Joe Biden?

[@varshabajaj9]

I am from India how we get casper cas9 please tell me my son suffer from dmd

[@Chloeeeeeex]

Varsha, I'm sorry to hear about your son. There have been some great improvements with CRISPR/Cas9 technology, including preliminary correction of duchenne muscular dystrophy. A cure is on the way; however, it will be a few more years (at least) until it is available. I have attached a link to a promising article published in Cell from earlier this year. Wishing you and your son the best. www.cell.com/cell-stem-cell/abstract/S1934-5909(16)00022-9