The Gillett Health Podcast: Tongkat Ali & Fadogia Agrestis

Welcome to the Gillett Health Podcast! In this episode, Kyle Gillett and James O’Hara discuss Tongkat Ali and Fadogia Agrestis.
0:00 Start
0:45 What is tongkat ali?
1:45 Is tongkat ali safe?
3:55 Tongkat ali and testosterone?
4:45 Rats on TRT and tongkat ali
6:00 Side effects of tongkat ali
7:05 What is fadogia agrestis?
9:55 Actions of insulin vs. metformin on androgen production
11:15 Theoretical clinical applications
13:30 Testicular toxicity and risk mitigation
17:00 Fadogia agrestis and luteinizing hormone
19:30 Female athletes and androgen levels
21:10 Talk to your healthcare provider
22:55 Gorilla Mind Sigma
26:35 Lifestyle for optimizing testosterone
33:55 Fenugreek
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For 10% off Gorilla Mind products including SIGMA: Use code “GH10”
►gorillamind.com/kyle

[@emmanuelramirez6593]

Here from the Huberman Lab Podcast - loved the level of detail that was presented and had to come over to this channel. I’m immeasurably grateful for content like this available for free. Looking forward to more from you soon!

[@MichaelLinggardjati]

SUCH A VALUEABLE INFORMATION

[@adamhopper1831]

great video, thank you, i started on tongkat ali recently, considering fadogia, but more inclined to stay away from it given the risks,

[@TypeJack]

I listened to this twice, once again, loved it

[@wolfingphysique3820]

Great conversation!

[@SCP-SAM]

Same..here from the Huberman Lab, great share on today's podcast

[@jesuschristislord7754]

Excellent information. Subscribed.

[@SwedenStreetWalks]

Hi From the Humberman Lab podcast, thank you it was really informative

[@doloresguertin9601]

Hi Kyle, Hi James, I too would like let you know your time with Andrew Huberman was very interesting and greatly appreciated and well divvied out in terms of female and male issues. I'm 65 and have been taking various forms and doses of BHRT progesterone for over 25 yrs, I've had to stop the biest and test, just cant handle it esp estro. I appreciate you vast functional knowledge about how hormones and amino acids and neurotransmitters work together or not, on so many shared pathways. Recently I have increased my taurine to 9-12 g/day to help with crohns, colitis and celiac and severe and extreme oxalate dumping (almost 3 yrs). I also take 1 capsule of TUDCA/day for liver dysregulation. The taurine is esp making a difference so I dont want to decrease or stop it. Like progesterone, it is a swiss army knife. This brings me to progesterone (currently on 320gm/night), sublingual, quick dissolve. More recently my sleep was suffering, followed by 4 days on no sleep, not even for 5 min. It felt like the GABA pathway was getting jammed up or overladed with either too much taurine or too much progesterone or both, resulting in what felt like this amino acid and hormone took the Glutamate pathway instead, leaving me feeling very unlike myself and excitedly toxic. I followed by taking a sauna every day for 7 days and I'm feeling and sleeping better, but I'm nervous to resume taking the progesterone. I have gone on pubmed, and reached out to various functional drs and also 3 different compounding pharmacists (the chemical engineers of medicine). One CP suggested progesterone resistance (I dont think I have PCOS which is closely assoc) and I need to stop it for a while then pulse it; the next CP, who filled the prescription, suggested to stop taking the taurine but he had no scientific reason; and the other suggested thyroid storm (which I am familiar with and did not feel like that is what it was). I would very much like to continue taking both the progesterone and taurine, but need to know how to proceed and if they are safe to take together. The prescribing dr does not know either, and she would prefer me to take the progesterone over the taurine, but that could have something to do with her being a prescribing dr. Thank you in advance for any thoughts or suggestions. I'll keep an eye out for you as look forward to learning more from you

[@jayv7933]

Hey guys, great Job on the info. I'm sure your podcast will do great, tons of us are coming over from the interviews you did with huberman... Just one piece of feedback, for those of us who don't understand the doctor linggo very well, it would really help to put your conclusions in simpler language. Anyway, keep it up!

[@daveduren5263]

Just came over and subscribed after hearing Dr. Gillett on Huberman Lab podcast ! Great information!!! I was wondering, what is the best way to find out the source of my TongKat Ali? I’ve been taking that and Boron since hearing about them on a previous Huberman podcast….and my testosterone DID in fact increase.

[@ethimself5064]

Just found your channel via Huberman channel👍👍Rock on

[@drp89]

Thanks Dr.Gillett. Could you also talk about how to lower estrogen in men?

[@lkpnda287]

Iʻve been having my hubby take tong for over a year because I live Dragon herbs and did my research and talk to their consultants they have and occassiinally iʻll tske it for a few months. We Love it and when Andrew H., mentioned about he was gonna talk more about it On an upcoming youtube I was stoked! But interesting as it was, The consultants I comversed with had much more information although I know he had other stuff to discuss with you on that episode. Thanks for the i fo though and noce to know this is getting some recognition in the western world as itʻs not well known in the United states as it is elswhere unless your expised to it like the holistic and acupuncture world. 👍

[@Anna-yf4gt]

Another Huberman referral… Looking forward to your content! :)

[@sydneymerunka4140]

Great information! Any Boron supplement recommendations (or Boron type)? What would be a good range to aim at for males, regarding Total and Free Testosterone? What parameters should we be looking at to determine if it is worth trying out Tongkat Ali?

[@GoldenGoat888]

I hoped this would better address the role of these supplements on Estrogen, specifically reducing estrogen levels to improve endometriosis and heavy periods. But, alas everything revolves around testosterone. Can you please suggest a podcast or resource on the topic of balancing female hormones?

[@pablopeleikis7110]

Great Episode. Is there any benefit to adding a HIIT protocol when already doing resistance training in termes of hormone production?

[@joaoamstalden6321]

Excellent content! Just wondering what is the best time to take these supplements...

[@manicmuns]

Great info, thanks! What dosages of Fenugreek and NAC would you recommend to take alongside Sigma?

[@YMESYDT]

You had me at "sexually vigorous rats"

[@robmagz]

New subscriber! What would be a recommended dosage for both those two types of herbs?

[@diamondmeeple]

Question: What a balance of carbs, prots and fat you recommend (in %)? It is important to keep the insulin low whatever foodplan yes?

[@fitlifeconrad]

What levels do you normally like to see? And also what’s your best way to drop sbgh?

[@Kikwatz]

Coincidence there was a long Nootropics Depot podcast about the same topics just 1 day before? Nevertheless, good information!

[@kurtcasablancas3453]

Make a vid about Tadalafil

[@TypeJack]

Hey guys, really enjoyed this content. I've gone through a lot of KZbin content regarding these compounds. This content was easily digestible and I would put it up there with more plates or hubermann. My question is, would you take these compounds?

[@gilletthealth]

We are not currently on these compounds. However, Dr. Gillett plans to take 1-2 capsule of sigma (with 150-300mg fadogia) some time this summer, for one month.

[@TypeJack]

@@gilletthealth cheers for the reply! You smashed it on the hubermann podcast!

[@informative_walrus]

@@gilletthealth I have some data I am willing to share. Reach out if interested.

[@singaporechickenrice2484]

what are the doses for fadogia per kg in humans? and whats the safest way to cycle it?

[@BANGbucketHEAD]

I've been taking tongkat Ali with fadogia agrestis and I feel really good on it

[@anguslean4058]

Do you cycle it ?

[@BANGbucketHEAD]

@@anguslean4058 yes I just quit taking both about a week ago I'm going to wait like 3 weeks and then start taking them again.

[@anguslean4058]

@@BANGbucketHEAD is it working ?

[@BANGbucketHEAD]

@@anguslean4058 yes they worked for me

[@JohnAbuklau]

what time do you take it everyday? whats the best time to take it during the day?

[@Andytenholder]

Adding my anecdotal heads up on Fadogia Agrestis. I tried the Barlowe's brand mentioned by Andrew Huberman on one of his Podcasts. After about a week of 600mg daily, I noticed that I had a constant urge to pee. Even after emptying my bladder, I still felt like I needed to pee. I stopped taking it after about 2 weeks and the feeling reduced to more tolerable levels, but it took months for things to return to normal. I did go to my PCP a week or two after stopping it, they tested me for a bladder infection and took blood. Nothing showed up as out of the ordinary. If things didn't improve they said I should make an appointment with a urologist. I didn't end up going to the urologist, mostly because I didn't want to get a finger up my butt. I suspect that the Fadogia Agrestis affected the size of my prostate, but not really sure.

[@gilletthealth]

Thank you for the anecdote! Your assessment seems correct, theoretically it can certainly affect the size of your prostate. As mentioned in the video, for most, we don't recommend more than 150mg or 300mg, if the patient is a candidate. Cycling it would likely help give the prostate/bladder a rest as well. We made sure that 1 capsule of Sigma "only" has 150mg in it.

[@darrenraphael]

Eat a lot of broccoli, pumpkin and pineaple. Your bladder should return to normal.

[@jonathandavistennrealtor]

I've had similar results with fadogia

[@krix0043]

@@gilletthealth thank you for the advice, sirs!

[@ericafghan2748]

Are your podcasts on spotify? I can't find you there...

[@gilletthealth]

Thanks for the comment! We are working on getting future podcasts on Spotify.

[@Bherrera012]

If your liver enzymes are elevated should I get off Tongkat Ali until I lower it ?

[@curtisstaggs5064]

You mentioned heavy metals in tongkat from Indonesia yet you helped create this product which gets its tongkat from Indonesia. Should I be concerned?

[@hetapolski]

tongat ali dosage 200-600 mg?

[@Anna-yf4gt]

Where can we get more info and buy Gorilla Mind Sigma? God bless!

[@gilletthealth]

Thanks, feel free to use GH10 as discount code if you want to support the podcast! Link below. (With 240 capsules thats enough for 120 days [plus breaks] at our recommended 2capsule per day dose! gorillamind.com/collections/build-muscle/products/sigma More info in below video (Derek, the company owner, and I spoke extensively over past year trying to design this as safe and effective as possible given current evidence): kzbin.info/www/bejne/o6vUemOOetSKm9U

[@peterprotege3310]

Hello Dr. Can you recommend supplements that will increase beard growth?

[@Hi-pg1tk]

I have a question about a supplement called natu roids natural anabolic complex and one serving has 350 fadogia agrestis extract 250 epicatechin and 200 tongkat Ali and I am taking 2 servings and would like to know if that is a safe amount or lower the dosage. I am 150 pounds 5”5

[@garyross7607]

Is it any good?

[@juan24camacho35]

♥️

[@amandamuellner6084]

I feel like you should have an intelligent interested person who doesn’t know what you’re talking about, who will ask questions, so you can explain your technical jargon better, I’d volunteer

[@italianstallion399]

4:38 I noticed there was an edit here. How long did you guys laugh about "sexually vigorous rats" lol?

[@alexanderbayer4348]

yall awkward asf but great content

[@mattdannald]

😂

[@davidspannos6423]

I went on a low calorie diet and I nolonger get a muscle burn or doms my total testosterone is 265 and my free is 134 I am deficient in vitamin D my clinician wants me to go on hormone therapy but at 900 per mounth it's not cost effective for me so I guess I will try gorilla mind

[@gilletthealth]

$900 a month is outranges if your physician recommended just "TRT"

[@davidspannos6423]

not just trt but vitaD and zinc and magnesium

[@davidspannos6423]

thanks for the reply it's a difficult position to be in when you cant build muscle

[@davidspannos6423]

I just ordered sigma

[@mikemcguire513]

Dude on the right must of broke his right arm at some point it’s half the size of the other

[@XavierCadavez]

Sigma balls lmao

[@th4ros96]

Nice ad. Meanwhile tongkat gets banned in EU.