The Great Niacin Debate: AIM HIGH, HPS2 THRIVE

[@justinojaca5293]

Any brand of Niacin you recommend?

[@PrevMedHealth]

Yes. Enduracin.

[@damiandamiano3651]

mallboro

[@nassermj7671]

@@damiandamiano3651 What have you been smoking? LOL! And on Enduracin, I'd listen to doc folks, but my personal experience.... Not that much different from Walmart stuff but the double, triple $$ price. Doc may clarify that all one day for laymen like me

[@damiandamiano3651]

@@nassermj7671 nicotine have same structure as nicotinic acid, nicin, and other nad preC

[@nassermj7671]

@@damiandamiano3651 - 🙂

[@davidbrown552]

To those who are frightened by the flush. "Oh, grow up!" Same to those frightened by completely swallowable pills. You're not taking them as a taste treat, child. Grow. Up.

[@vericacvetkovic9093]

Take it at bed time n you will sleep through it.

[@c4p4c1t1v3]

It's really not that bad. I came down with a bad sickness recently and lemme tell you nothing will compare to the constant agony of disease. just started taking 125mg 4 times a day and will bump it up the dosage a bit soon

[@domenikschmitz334]

I really enjoy the flush. It feels GREAT!

[@OnochieAfigbo]

I do enjoy the flush. I take niacin after meals to reduce the intensity, though.

[@bojax3434]

Right. I think people talking about having a bad “reaction” to niacin are describing the flush. It’s that way for everyone! Embrace it! To me, it feels like a more intense beta alanine tingle! Suck it up

[@robertolson3115]

I appreciate your honesty in saying you can't promise taking niacin helps the end point. I took a big interest in heart disease a long time ago. Studied it hard for 12 years. After the recent string of failures of drugs that did all the right things, but failed to improve outcomes in heart attacks and strokes, I came to the conclusion we were treating a lab report, and not the disease. Thank you for posting these videos.

[@PrevMedHealth]

Thanks.

[@spek2554]

"Treating a lab report and not a disease." I like that. Sorta like "Rubbing an aspirin on the forehead."

[@michaellns2860]

0pp9p99p0l0

[@iwnunn7999]

I made the mistake of taking niacin before going to work one day. It kicked in about midmorning. I turned beet red and coworkers thought I was dying.

[@vericacvetkovic9093]

@Ricardo opina Thats why i take it at bed time. So even if it happens i am sleeping and not know.

[@OfftoShambala]

That’s awesome... I will have to try that some time. Lol

[@jamiami3804]

I took it once when I was giving blood, I thought they took too blood and I was dying.

[@jameshumphrey9939]

first world problems : )

[@gramps5157]

I did the same thing and while driving to work I actually got out of the car because I thought the seat was on fire. When I got to work I saw the company nurse and explained what happened. Her first question was did you just recently take Niacin. I asked her how she knew that and she said that I had the classic Niacin reaction.

[@trevorbuchanan6226]

A very big thankyou dr. For taking the time to do these uploads and shareing your vast knowledge and experience . May GOD Bless you for your kindness’s.

[@lunam7249]

Wow! An md withreal knowledge and common sence. What a blessing on earth you are

[@PrevMedHealth]

Thanks.

[@PrevMedHealth]

I really do appreciate that comment!

[@malabikakulkarni849]

World is full of intellectually challenged and they judge other people by the ability they have been blessed with. Dr Brewer please don’t take the comments by these kind to heart. Instead feel sorry for these kind and have kindness in heart to forgive their lack of knowledge, education, understanding, almost everything that you will hold as desirable in a human being . Please don’t feel bad by these comments

[@jameshumphrey9939]

yes, he is great until Ai and automation replace us all from work and professions : }

[@JESUSisGODourSAVIOUR]

It's Vitamin B 3 not D 3.

[@PrevMedHealth]

Thanks. I know. Listen to the rest of the vid, and watch the captions.

[@EduardoSantos-qj2ni]

B3!

[@marilynreno7510]

he said d3 so many times

[@marcopolo9146]

Marilyn Reno but we understand what he is talking about, right?

[@swahili9144]

How much niacin should you take ofnyou have a pellegra?

[@jesuisravi]

Niacin and depression: I can attest from personal experience that the former is VERY helpful for the latter.

[@PrevMedHealth]

Thanks. Very interesting.

[@PrevMedHealth]

Very interesting.

[@cherylmcduff5388]

Agree. Really good. Beats anti depressants hands down.

[@artsiecrafty4164]

It worked. After getting over the flush, I spent most of the day smiling and active!

[@c4p4c1t1v3]

My doc tried putting me on anti depressants again. don't want it. Just found out about Niacin and just ordered me some. I'm optimistic it will help

[@edwardchoi8299]

I am 53 year old and 65 kg and 164 cm height. I took 1.5g of Niacin for about 2 months to reduce cholesterol. Positive effect was my blood pressure went down from 140/90 level to 110/70. I have not check my cholesterol level yet. Negative effects were nausea, vomiting and cannot take meaty food. I totally stopped Niacin for two days and these symptoms disappeared, but my blood pressure went up again. I am taking 500mg a day now for a week without much of side effects. I am worried with liver damage from niacin. I am wondering if any reported severe liver damage from Niacin. Thanks.

[@PrevMedHealth]

Thanks. Yes. Liver damage has occurred with niacin. It’s pretty rare. But it has happened.

[@psisavath]

I read the liver issue was a research done with rats, and they gave the rats the equivalent of 200 grams of Niacin to a human.

[@bojax3434]

The damage/toxicity is also related to the sustained release niacin. Just take the regular type and embrace the flush. It just means your blood vessels and calories are opened up. That’s it! 🤷‍♂️

[@arthurrobey4945]

Dr. Horrobin "The Madness of Adam and Eve" that niacin does not cause flushing in the Schizophrenic. He also discussed prostaglandin.

[@JesusIsLord1976]

Would a cold shower help if flush is to intense?

[@Chickydrie]

Not really. Try to take it with some applesauce or yoghurt.

[@mgreen9316]

Any thoughts about taking TMG along with the Niacin. I've heard taking 1g of TMG for every gram of Niacin minimizes any potential methylation.

[@myscreen2urs]

Wouldn't it maximize methylation? I thought TMG was there to promote methylation

[@richtygart6855]

I've got a full bottle of 500mg niacin and I'm terrified to take any more of it. I did it one day and had a reaction and then skipped a day and tried it again and I haven't done it for a week since. I felt like I fell in a pool of poison ivy. The itching was torture.

[@edv9483]

Start with lower doses and work your way up. The flushing effect will still be there but better tolerated.

[@bojax3434]

The flush is completely harmless. I think you are hyping yourself up with worry and it’s basically anxiety regarding the flush. The flush is WHY you take niacin to begin with.

[@Chickydrie]

Try to take it with some applesauce or yogurt ...😉

[@Moogles1982]

ROFL!! I’m in exactly the same boat as u. Took my first 500mg last week and was convinced I’m getting a heart attack. As the flush progressed to my stomach, I was convinced I’d puke the whole thing out, and then my feet felt like they’d evaporate. Haven’t taken one since but really want to get used to it!

[@geecee1990]

Just found your vids, subscribed and I'm already hooked. Have exercised at a high level all my life and even though I'm an IT guy I've always had a huge interest in medicine and really enjoy researching things like what you present in your vids. VERY HELPFUL. Please keep up the good work :)

[@PrevMedHealth]

Thank you very much!

[@gswguy4554]

@@PrevMedHealth did you say you recommend the Rugby brand or the Enduracin???

[@50quid11]

I was glad you kept saying D3... It helped me do a better job of paying attention! Really appreciate you reaching ou to the rest of us on you tube!

[@davidgollop2807]

is not niacin B3?

[@silverlake973]

@@davidgollop2807 it is B3 - got it wrong lol

[@RobertMertensPhD]

Seems like only yesterday I commented down below. Four years later, I've quit all of the doctor medications (Lisinopril and other stuff) a long time ago. I still take the Niacin, twice daily, 500mg. I get a flush in the morning after breakfast and nothing in the evening after dinner. I still don't get that. These days, many heart doctors are recommending ketone supplements for their patients. Apparently, now you can buy ketone supplements. If you're on a ketogenic diet, I assume you don't need them.

[@PrevMedHealth]

Thank You For Sharing That! Join Our Live Broadcast Every Wednesday! @11am EST. For more information please visit our website prevmedhealth.com/ & www.jubilee.health/. To learn more watch our videos on KZbin kzbin.info/door/moEsq6a6ePXxgZeA4CVrUw

[@eileen881]

I am so confused. 60 year old female recently diagnosed calcium score and very high LPa apparently heterozygous with high level of food sensitivities...whatever that means. I would like to lower LPa with B3 but instead put on Crestor which apparently raises it and Zetia which I think has something to do with the food sensitivities. Providers always too busy to explain anything. One doc says B3 and another warns of stroke association.

[@usachiropractic]

Doc what is a good dosage of Niacin for an 82y.o male with heart disease

[@drjosephsmaresca8256]

Why did my high SED rate go down when I took niacin consistently?

[@lilystonne4108]

Yes, I agree that the 0.1% variance in hba1c is not significant. You convinced me a while back that niacin is more beneficial than not. I have been working with a naturopathic doctor who had introduced me to niacin in the first place. I had just wanted you to reassure me of its safety. The frustrating thing is that being on a ketogenic diet and 16/8 intermittent fasting for 12 months only lowered my hba1c from 6.3 to 5.9. Then taking niacin bumped it back up to 6. So annoying! I am so convinced it's the Amilioride HCL/HCT 5/50 that is keeping it high despite my efforts. Will try to get the nephrologist to lower the dose. Thank you Dr. Brewer and Mr. Lorscheider for your help.

[@ronbonick4265]

Me too Doc. , it seems to be common sense that it increases blood flo- so It must be good for circulation .and I hit the vitamin C hard too. My BP last nite was 120 72 im 54

[@ronbonick4265]

I havent had a blood test in 5 yrs.. Not sure,,, I watch my diet really close . No greasy food, no sodas, lots of green drinks , spirulina , alfalfa green drinks , Carrot and beet juice etc

[@LB-sw2km]

Does niacin hurt the liver ?

[@KumarKumar-kx4ct]

If someone on Niacin (flush version)for over 4 months up to 2gm a day observes 36 HDL in lab readings, what can be surmised about that? Should it be taken much longer to see better results?

[@wolfcub1483]

I take just before bed one regular flush Niacin 500mg and if flushes , is when I sleep, no problem. I also take twice a day 500mg each of Niacinamide which is different and also a multitude of other antioxidants. At 72 my BP is normal and so far most everything is under control..and working to change the ED condition..perhaps this subject is very important to most men to address at some point Doc..Please move your microphone up closer for better sound clarity and volume. Thanks !

[@bls5160]

Take b6 for ED!

[@davidanderson8469]

Look for the USP label or a reputable 3rd party testing. Consumer Reports analyzes supplements regularly and finds the contents are all over the place.

[@_Trakman]

What's a good low starting dosage... And a dosage to build up to?

[@PrevMedHealth]

250 my up to 2 gm (2,000 mg)

[@mcreyfonacier1982]

I almost bought the "no flush" version. Thanks Doctor Ford.

[@PrevMedHealth]

Thanks

[@marcopolo9146]

I bought no flush before I watched this video.

@@marcopolo9146 me too …a big fat kilo 😬

[@kathleenmorris811]

I was taking 1500mg and my ankles blew up and so did my legs. Very uncomfortable. Now I'm taking 750mg, will that dose do any good to lower #'s?

[@PrevMedHealth]

Thanks for sharing that.

[@kathleenmorris811]

I've stopped taking niacin all together now

[@big_bee07]

@@kathleenmorris811 Did it lower your cholesterol numbers?

[@kathleenmorris811]

Brandon Crisp, I don't know as I took it for a short period of time.

[@big_bee07]

@@kathleenmorris811 I'm taking garlic and if my numbers don't go down than I might try niacin.

[@Carrival]

Thank you for these wonderful scientific videos!!! I always ask why?...you always help us to understand!!! Ordering some niacin extended release today!!

[@PrevMedHealth]

Thanks. Please share them with someone that could benefit from the information.

[@taylorwhite3636]

@@PrevMedHealth Hey there Dr Brewer. Thanks for your videos, niacin wasn't on my radar but now it is. My concern w/ niacin has to do with its effects on blood glucose. I've read trials where ER niacin + crestor raised HDL (vs statin monotherapy), but also raised fasting glucose. Do you advise niacin for people that have advanced prediabetes & already take a statin (like rosuvastatin)? How about lower dose (~500mg ER) for someone with elevated, but not statin-level, lipids? My whole family has blood lipid/glucose issues..! How do the pros/cons stack up in that sort of scenario?

[@henrychan6792]

Taylor White ，

[@pat557]

The flush I can handle; its the 2 day headache that Niacin causes me. Used to take Niacin for years...then I stopped for a few yrs. When I started back up, 2day headaches are the norm. Why? I only use straight Niacin, not slo niacin.

[@pat557]

Follow up: realized I was using really old bottle of Niacin; bought some new Niacin bulk powder and no headaches. life is good

[@Freddie1M]

Would you recommend taking Niacin as well as statins?

[@indention7]

Dr. Brewer, Is niacin safe for people who had af. I have read it can cause irregular heartbeats. Thanks

[@PrevMedHealth]

Do you mind providing the sources where you heard that?

[@hugorojas1452]

You're THE BEST Dr. Brewer! Thank you for ALL you do for All of US! I post you on Facebook and my 5k viewers regularly! Geez, I wish you were local in Los Angeles so I could have a visit with you! Ever do events here?? Best to you! ; o ) Hugo Rojas

[@LS-oy2fi]

Hugo Rojas w

[@Roneck888]

This doctor kept caling it D3...geeeezzz. My issue was/is calcium. I needed a 3:40 triple bypass CABG. I take 20mg.rouvastatin, 81mg. aspirin, 6.25 x2 coreg and i asked my surgeon if i could add Niacin and he said yes so i added 250mg a day so maybe it can't hurt. Calcium BTW cannot be reduced by medication so i will probably revisit my surgeon in 10 years or so.

[@Chickydrie]

Read about magnesium & vitamin K2-Mk-7...🍀

[@Competitive_Antagonist]

The flush seems to be important. Plus there seems to be hepatoxicity with the extended release version. I'm using to treat my alcoholism and helps reduce the anxiety. I can feel it coming on and always induces a great calm that can last for a couple of days. I'd probably experience even greeter improvement if I was to give up smoking cannabis, though I started to help me deal with the dreadful summer heat.

[@PrevMedHealth]

Thanks for sharing that!

[@paulfesler7052]

Does niacin help with insulin resistance? If so what kind do you recommend and how large of a dosage

[@erharddinges8855]

Another problem is Niacin in combination with other medicines -( Aspirin) and prediabetes /Metformin) and the question of live detriment. Only try and see?

[@PrevMedHealth]

+Erhard Dinges Many people are on Metformin, Aspirin, and Niacin. I am one of them. It is not a known risk.

[@erharddinges8855]

Will try again and start with 500mg Metformin on evening and watch my muscles. Ramipril 2x5mg makes my voice thin and weak. (as yours?!) Candesartan worked better. Will switch to a combination- 5mgRamipril and 8mg Candesartan.

[@PrevMedHealth]

+Erhard Dinges please be careful of the ARB/Ace inhibitor combinations. They create risk. Let me know if you can't find information on that.

[@erharddinges8855]

Did not yet start this combination. If, I will do it under control of my doctor.

[@PrevMedHealth]

+Erhard Dinges www.ncbi.nlm.nih.gov/pmc/articles/PMC3183919/. Ace inhibitors and arbs together tend to increase side effects, but don't increase desired outcomes.

[@ethanoyamawang]

2grams a day? I Just order some for my cracked heels. Hope it will help

[@cosmichealth3907]

For that u need b 5 and b 2 and b complex

[@ethanoyamawang]

@@cosmichealth3907 Thanks !

[@erharddinges8855]

When taking niacin 2x2 a 500mg, it makes hyper- and polyuresis, so I am forced to reduce the dosis. You did not watch this side effect? Seems I am a specialist on having them.

[@PrevMedHealth]

+Erhard Dinges The side effects with flush have dominated the niacin group. And they really haven't been a problem for those taking timed release. I agree - you do seem to be have unusual side effect experiences.

[@nknownnknown7613]

I take 3g no flush no nothing

[@KiTTeNChaoSS]

Did I hear Dr Brewer state he takes 2 grams a day? As in 2000mg?

[@geraldfriend256]

I thought it was a typo myself.2gs is huge dose obviously.But yes he seems to take 2 gs

[@realperson6201]

Hello Dr Brewer, You have said you take Crestor. If all cardio disease is related to insulin resistance, do you feel it is ok to take Crestor, which lists diabetes as one of its major side effects? At what dose is it still considered 'low dose'?

[@dr.truthteller9768]

How the hell can I take more than 300mg because that's my threshold. I can't imagine taking more. At 300mg I feel like I'm on fire and my heart rate goes through the roof and I get slight confusion like I'm stoned or something for about an hour and a half. I'm on TRT so I know that supplementing with Niacin is important. Suggestions?

[@renekukard9279]

Stick to your dose.

[@Chickydrie]

Up the intake of foods that are rich of magnesium & try a B-complex. When it's only during the flush, try to take it with some applesauce or yoghurt. 🍀

[@carolinalomeli9128]

Can I take Niacin if taking Lisinopril, Metoprolol and Atorvastatin?

[@cosmichealth3907]

Yes and add b complex too and monitor your bp daily...

[@allison481959]

Question can Niacin Make all yours joints,wrists,ankles etc hurt terribally,i started niacin on my own less than 2 months ago, was taken off lipitor,because after taking it for over 10 yrs it gave me Myositis of the legs?

[@allison481959]

What can happen if your liver enzymes are raised?

[@pelonete5000]

HI Dr. Question: I use to have a big chunk of arugula and beets (nitrates and NO) as a late night dinner , do you think is contraindicated to take the niacin in that meal? Thanks

[@PrevMedHealth]

No.

[@pelonete5000]

@@PrevMedHealth Thanks!

[@veritas2022]

What type of niacin do you recommend? Any comments on tablet vs capsule? I tried non flush niacin capsules but didn't feel the same effects as niacin that gave me flush.

[@orithfrankel2151]

Veritas, read the doctor’s explanation under the video at the top of the page. Midway through his explanations, there is a paragraph that begins with, “Debate started in 2011 with 2 studies...” wherein he explains the drawback of the niacin with the Laptopriant added.

[@DRHOPE7]

Dr Brewer; when is the best time to take the extended release niacin (your brand); i have IBS -D? Many tks and happy new year.. i'll follow your 2018 videos with happiness and health hopefully

[@PrevMedHealth]

Thanks. No time of day is preferable for extended release niacin. If you like to shower soon after your niacin dose for flush reasons, plan it around that.

[@72bronxboy]

Hi Dr. so should I take it without the flush?

[@renekukard9279]

With flush.

[@waynehendricks8187]

Thank you for the information about Niacin. My doctor wants me to go on statins but after reading about the side effects I think I will start taking Slo Niacin instead to clean out my arteries. The pills I just got are 500mg per tablet. Would you please tell me if one tablet per day will work for me? I am looking forward to your reply. Thanks again.

[@indention7]

On a number of medical websites. Webmed, Cardiosmart and Mayo Clinic. Thank you for taking the time to reply.

[@hovnarren]

One side effects I have, well I have many, but one is that teeth gum seems to swollen up after niacin intake with flush. Also it feels like front teeth will pup out, why is that ? Is that normal reaction. I take around 1 g niacin.

[@PrevMedHealth]

Thanks for sharing that. I’ve never had anyone talk about that problem. And I’ve never seen it reported.

[@hovnarren]

@@PrevMedHealth Ok well I have other side effects like cold body and hyperactive at the same time, after taking niacin. This comes a couple of hours after, is this normal or why does this happends to me ?

[@scottstores6801]

Dr. Thanks for all your help. I've been taking SLO Nia. brand name made in your area. Do you have a opinion on this brand.

[@lester9244]

SLO Nia increases liver dysfunction

[@meshaedwards5940]

Am I to understand from these study findings, that niacin benefits are not effective if taking statins?

[@arthurkuper245]

Does niacin increase insulin resistance and increase the risk of diabetes?

[@PrevMedHealth]

Yes. For a few months.

[@reneronquillo753]

Are you going to share your Advanced Lipid panel, Small LDL particle, Lipoprotein a, homocysteine, CRP, insulin levels. I would love to see your current scores.

[@PrevMedHealth]

kzbin.info/www/bejne/iqu0iaCtardnrZY kzbin.info/www/bejne/oobSfnp_ocmia5o

[@justinojaca5293]

I just discover your channel and subscribed. Would you advise fish oil instead of salmon?

[@PrevMedHealth]

Join Our Live Broadcast Every Wednesday! @11am EST. For more information please visit our website prevmedhealth.com/ & www.jubilee.health/. To learn more watch our videos on KZbin kzbin.info/door/moEsq6a6ePXxgZeA4CVrUw

[@arunprabu6570]

Doc, what is your recommended niacin brand ?

[@PrevMedHealth]

Hi. You can check the Endur-acin extended release version on our product page: prevmedheartrisk.com/products.

[@v.j.l.4073]

@@PrevMedHealth So extended release is not the same as non-flush? Trying to get all the terms straight.

[@TrishTruitt]

Very helpful. A Dr put me on niacinamide but now I only use real Niacin. The flush was a bit a pain but now it doesn't bother me. even when I feel it - I kind of enjoy it now.

[@downbntout]

Trish Truitt Same!

[@TheJimmyswe150]

I low the flush, specially when you just take a bath or before bed, makes you so calm

[@evab2132]

Doc, it's true that extended release Niacine causing liver damage. And with regular Niacin is recommended to take TMG( glycine) because niacin effect on liver metabolites.

[@PrevMedHealth]

Yes. I take TMG. & anything can cause damage, niacin as well.

[@ppujals3]

You did not mention it causes muscle weakness. I have to check all vitamins to make sure it doesn't contain any niacin. Within a week I can not walk up a flight of stairs.

[@ppujals3]

@Ahmad Qahtani No

[@bojax3434]

I have literally not seen this claim anywhere. Now, if you are taking a statin with it, well THOSE cause muscle issues.

[@Chickydrie]

Some people can have difficulties with some medicine, foods and other things. Like allergies, hormones out of balance, too much copper, iron, sugars. Less of omega 3, magnesium, vitamin C! Or a liver that's not working properly... when you're on cholesterol lowering or other meds, also taking niacin can be too much to handle.

[@frankiefernandez5252]

16 Foods That Are High in Niacin (Vitamin B3) Liver. Liver is one of the best natural sources of niacin. ... Chicken Breast. Chicken, especially the breast meat, is a good source of both niacin and lean protein. ... Tuna. Tuna is a good source of niacin and a great option for people who eat fish but not meat. ... Turkey. ... Salmon. ... Anchovies. ... Pork. ... Ground Beef.

[@Chickydrie]

How much of these do you eat to get a daily dose of 2000 milligrams...?😇

[@colchicine1]

What does it mean if I only experienced the flush the first time of taking 500mg of niacin? I continue taking it but don't experience the flush anymore.

[@mystyboarder910]

Take on an empty stomach or 3 hours after your last meal.

[@ChillFantasticFive]

Should I take 2 grams all at once or split the dosage (pure powder). I don't mind the flush. Is it easier on the liver to take all at once?

[@PrevMedHealth]

That's debated. But my review indicates that it does not matter

[@r0b0tcat]

Dr Brewer, would taking niacin counteract the benefits of Metformin? I read that niacin can raise blood sugar levels.

[@dexterlacroy4132]

I enjoy the flush, especially in the winter season, wouldn't wanna avoid it.

[@PrevMedHealth]

Thanks. Good for you. I think I will try it.

[@davidgollop2807]

@@PrevMedHealth i enjoy it too

[@kenrach9875]

Did you once recommend Endur-Acin brand of niacin? And should we take regular niacin with the flush or extended release. ..thanks

[@andrewholt8356]

Would you say rugby extended release is better or rugby immediate, which would you recommend to be the most effective?

[@blessedamerican3541]

If I am following you correctly, since nicotine seems to help Parkinson’s patients, shouldn’t Niacin help them as well?

[@PrevMedHealth]

I don’t know

[@sparksfly2557]

What do you do when HDL and LDL are extremely abnormal and Triglycerides are 100?

[@michaelferguson9679]

Is risk great enough to not use niacin with Crestor?

[@PrevMedHealth]

I don’t think so. I use both, & have a lot patients using it.

[@akanecortich8197]

I buy the Rugby nicotinic acid Niacin proper. I note that the 'slow release' version may be more harmful to the liver. I also have the other B3 version nicotinamide... and noted that apparently..." Nicotinic acid is a B vitamin that is available without a prescription as a vitamin supplement (niacin). The nicotinic acid form of niacin lowers cholesterol, but other forms of niacin do not. These other forms that do not lower cholesterol include nicotinamide and inositol nicotinate (also called no-flush niacin)." WebMD

[@tommydinob]

I’m a pharmacist. Concur with your choice.

[@michaelmarli3518]

WE ARE IN SÃO PAULO. MY BROTHER WLADIMIR IS SCHISOPHRENIC. IT IS 1 MONTH HE STARTS TO TAKE NIACIN 500. HIS VOICE IS EXCELENT. HE STOP PED TO TELL WRONG THINGS. HE IS NO STORBORNED. HE IS BETTER SOCIALLY. HE IS 43 YEARS HE GOT SICK WHEN HE WAS 16. HE IS EXCELENT MUSICIAN.

[@jorieraine]

can you message me? I want to find out more about your brother and if the niacin is still working for his schizophrenia? Thank you

[@lallakebbeh5535]

How is your brother? My son was diagnosed with Schizophrenia at age 14 he is now 25. How is the niacin still working for your brother? Pls reply here and at [e-mail]

[@taylorwhite3636]

@@lallakebbeh5535 I really highly recommend against basing schizophrenia treatment on a youtube comment...

[@groovyme1234]

My 45yr old sister was diagnosed with schizophrenia 15 yrs ago and was put on anti-psychotic drugs. She recently started taking niacin and is almost completely normal again. She is slowly reducing her anti-psychotic drugs and everyone is amazed at her recovery. She started off with 200mg of Niacin and now takes 2000mg of Niacin a day. She is back to normal, it's nothing short of a miracle!

[@jeanpaultongeren125]

is she still cured@@groovyme1234

[@natev9022]

Niacin did a really good job of improving my lipids as well as significantly lowering my Lp(a), but it gradually increased my fasting glucose. Is there a way to prevent this side effect?

[@PrevMedHealth]

Niacin’s impact on glucose usually resolves within 6 months.

[@Rhythmandosyche]

Nate V can I ask what dosage and time of day you took it at?

[@mikeanthony8699]

How do we know the Loproprion cause the niacin not to work rather than the niacin just being ineffective in HPS2 THRIVE.

[@PrevMedHealth]

+Mike Gaiso Good question. It confused the American medical community. But it didn't confuse the Europeans. They still include it in their guidelines. The whole world, including the Americans, was using it before. There was just too much science supporting it. Did you check out the prior studies and lit reviews?

[@cometier]

There’s a pesticide that’s basically synthetic nicotine. Might this residue on food create a problem for humans?

[@PrevMedHealth]

Hmm I didn’t know that. You have to wonder.

[@bedweljp]

What’s the difference if you buy Nicotinamide and Nicotinamide R.

[@mujahidalikhan4342]

👍 Usually Nicine comes with Vitamin B Complex, IUsed but don't work, also vitamin b complex only useful for skin fairness 😎 Thanks for sharing great knowledge.

[@PrevMedHealth]

Thank you very much!

[@artsiecrafty4164]

I have a painful knee bursitis. The niacin flush is causing the pain to go away! I’m taking regular niacin, cut the capsule to about 100 mg.

[@green15838]

I love that flush!!

[@PrevMedHealth]

That’s good for you!

[@viorelg9499]

The number of idiots who give one star reviews because they ended up in an emergency rooms because they didn't know better is ridiculous.

[@suzytru]

I always liked it too, especially in cold weather. Better than a hot flash!

[@hovnarren]

If you dont get the flush by taken 1 g niacin, what has happend then ? This happen to me very often and its disturbing.

[@geraldfriend256]

Beta-Alanine does the same tingle..And the more you take day by day the effect lessens, as with niacin.We used to love the cheap thrill aspect.

[@jorgokodras1967]

Can you take niacin while on a small dose of aspirin and beta blocker ? Great video BTW!

[@Steven-gc6os]

I read to take 325 aspirin 30 minutes before taking niacin reduces the flush, so yes. But I’m not sure about the blocker

[@trivet1970]

Hi Dr. Ive seen that 500mg is the maximum recommended dose and your taking 4 times that. I have been taking 500mg should i increase ?

[@trivet1970]

thanks Dr.

[@sammymoore5050]

I appreciate your help so much. Looking for some Niacin but the ingredient list never mentions Nicatonic Acid. I only found one and it said "as nicatonic acid" not sure if thats a sly play on words or legit. Are you able to give any suggestion s on the best quality to purchase?

[@sammymoore5050]

John Lorscheider. Thank you so very much.

[@PrevMedHealth]

Thanks, Sammy, for your interest. And thanks, John, for your interest and help.

[@loism1965]

Dr. mentioned the Rugby Niacin brand, I purchased mine on Amazon. The regular one NOT the flush free or extended release one. I believe the flush is necessary once the manufacturers start changing the chemical composition of the mineral it's not going to perform the way it should. I heard Dr. Abram Hoffer in one of the many videos I've seen say if you take the Niacin with food you may not experience so much of the flush. So that's my 2 cent's on the matter. Good luck.

[@lisad2461]

You're saying D3, WHY??

[@warrenraffensberger4152]

Lisa D lack of experience...

[@davidivers9295]

he means b3

[@Qbald12345]

He responded to another person and indicated that he speaks about D3 frequently and simply said D instead often B out of habit. That hardly amounts to a "lack of experience".

[@and2409]

Is niacin useful for stroke recovery?

[@sonyb8017]

Dr. Berg has a KZbin about strokes. He mentions niacin in the video.

[@PrevMedHealth]

I haven’t seen the science on that.

[@nesspatinio7807]

Thanks for that enlightening info!👍🏻👏

[@PrevMedHealth]

Thanks!

[@ianpearson8976]

niacin i tried various doses but it gave me a fast hard heart beat.I would wake up at night heart pounding and that worried me.The mood effects were excellent but i had to stop due to heart.I am trying niacinamide to see if same side effects.

[@ianpearson8976]

i was waking up in the middle of the night heart pounding hard in the chest.Its was definetly the niacin.Actually when you search google its a side effect it says.i was getting this even at 500mg a day.The mood enhancing properties were good and i enjoyed the flush otherwise.

[@ianpearson8976]

the type i took was regular nicotinic acid.I noticed it more at night in bed than during the day.The flush doesnt bother me at all.

[@akanecortich8197]

panic attack? were you anxious about taking Naicin?

[@ianpearson8976]

Akane Cortich no panic attack. Just heart pounding at night in bed. I now take niacinamide no heart pounding from that.

[@ianpearson8976]

niacinamide has no effect on my mood so ive gone back to regular nicotinic acid.I have found taking a powdered form doesnt give me heart palpatations vs the pills.I dont know why this is.

[@lifestationexpresslinda9425]

So, that's what it is!!! I thought it might be the garlic. I'm taking niacin. Thanks!

[@geraldfriend256]

Garlic+niacin for blood pressue

[@lilystonne4108]

Hi Dr. Brewer! Does niacin raise blood sugar?

[@lilystonne4108]

John Lorscheider Thank you for the reply. I was taking 750 mg of niacin for 3 months. It lowered LDL-C to nearly ideal, but raised hba1c by 0.1%. I was disappointed because it happened on a ketogenic diet. I am beginning to suspect the hydrochloridethiazide that I have been taking for 20 years for kidney stone prevention. Will discuss it with the nephrologist at next appointment. Meanwhile, I will lower niacin to 400 mg and see what happens for next blood test in May.

[@PrevMedHealth]

Thanks. John’s right. The benefit of niacin outweighs the risk.

[@christophermarfleet1342]

It gets rid of my migrians instantly

[@harmono8766]

Didn't you say that extended release doesn't work?

[@robrae14]

After 6 months on 2000mg of Niacin my Lp(a) dropped from 204 nmol to 72!!! and my LDL from 119 to 68.

[@PrevMedHealth]

Congrats!! And thanks for sharing.

[@akanecortich8197]

2,000mg sounds like a lot. I take 500mg (nicotinic acid) in an evening, and still get a little flush.

[@robrae14]

Akane Cortich take extended release - no flushing

[@PrevMedHealth]

Thanks. Yes.

[@PrevMedHealth]

Smaller dosages have limited impact

[@99mak99]

So why did the “AIM HIGH” study didn’t show improvement niacin ?

[@renekukard9279]

Was tested together with statins. On its own it’s good.

[@levedia]

What is your opinion about b complex ? Mine says niocin (niacinamide) How do we know if its the right niacin were getting. Thank you doctor i appreciate your work.

[@PrevMedHealth]

Thanks so much. I will say a couple of things. There are some bioavailability issues. We only use 3 kinds of Niacin: 1. Rugby; 2 . Enduracin; and 3. Niaspan. Re: b complex - this is far more important for those of us that have methylation issues. John provided the details on this earlier this week.

[@levedia]

Thank you for the reply Doctor. One last question when its an appropriate time to take niacin along with b complex cause i take both. Is lunch time ok ?

[@TheJimmyswe150]

@@levedia yeah you can take it whenever, maybe not the b complex as it can give you alot of energy

[@ABrighterToday4Us]

I need some clarification. You state taking 2 grams (2000 mg) yet I was told Men: should be 16 to 25 milligrams daily. Please explain how my body can handle the extremely higher amount 2 grams (2000 mg) you suggest. I need the benefits you are describing. Someone else suggested I use Trimethylglycine (TMG) powder for better control over the higher dose. I was told to match my Niacin dose to a corresponding dose of trimethylglycine (TMG). Dr. Brewer will this help?

[@PrevMedHealth]

I agree.

[@downbntout]

Mr. Lorscheider, this carefully considered reply could be reposted in the main comments and pinned to the top, bc I see others asking the same questions

[@PrevMedHealth]

That’s a good point. It would help to pin this and other key responses.

[@YERUBILEEtheBand]

Yes please pin this because Dr Chris Masterjohn pointed out that high niacin without TMG can lead to depression and waste of creatine.

[@bojax3434]

16-25 is some FDA generated number to not be considered deficient. Not deficient is a far cry from optimal. This is the case with most supplements. The FDA are fools. They use the 400 iu figure for D3 and that is ONLY for bone and teeth benefit. Problem is, D3 is involved in hundreds of metabolic processes in the body. The FDA has no idea what the optimal level for d3 is, or niacin. And probably anything else.

[@bedweljp]

Has the flush any negative effects

[@jorgeluisrodrigues1322]

No.on contrary, it'll be beneficial.

[@RobertMertensPhD]

Thanks again for another great video, Dr. Brewer. For some reason, I thought Niacin and Niacinamide were the same thing. Apparently, Nicinamide is supposed to be the flush-free stuff, which seems to be effective on mental impairments, but not on heart disease. I used to look forward to the Niacin flush, but now they say, after a couple of weeks, you don't get it anymore, so it's only a temporary effect. For now, I take only 500 mg daily (morning/evening), but I might consider upping that. Now, should I still be taking that with Lisinopril? Who knows. The next big question is whether Niacin alters our cellular levels of nicotinamide riboside (NR), or am I thinking of Nicotinamide Adenine Dinucleotide (NAD+), which is reduced in our cells as we age, but which is one of the Sirtuins, which act as "gene snippers" that turn off the genes that make us age (if my old memory serves - I may have to go back and review those papers). Apparently, a lot of our "Nico_" enzymes are derived from Niacin, so perhaps it helps, and might be a less expensive alternative to NAD+ supplements (which you can now buy, but are very expensive).

[@PrevMedHealth]

+Robert Mertens Yes. Niacin, niacinamide and nicotinamide are related. And Nicotinamide Adenine Dinucleotide (NAD) is converted by NAD phosphatase and NAD Dehydrogenase within the mitochondria during oxidative phosphorylation. It's part of the cell respiration cycle that's so much more efficient than the primitive metabolism of fungi.

[@mikewellwood1412]

The way to cope with the flush is to start with very small doses, e.g. 25 mg, and slowly, very slowly, build up. I regularly take the 3g or so per day, suggested by Dr Abram Hoffer, and provided I keep it up every day, barely notice a flush. It only comes back if I leave off niacin for days at a time. I use pure nicotinic acid powder, either mixed weith water and drunk through a straw (it doesn't taste particularly good), or ideally put into gelatin capsules. I usually mix it with vitamin C powder to make this process easier, as the niacin powder is very fine. In any case, Hoffer recommended taking vitamin C with it. Like some others, I don't mind the flush when it occurs; in fact I quite like it. The thing is to be prepared for it, and expect it. I can imagine it would be alarming if you had no idea what was going on. Great video, but it might have been nice to acknowledge Dr Abram Hoffer's part in the history of niacin therapy. See his book: "Niacin: The Real Story".

[@PrevMedHealth]

+Mike W Ellwood Thank you foe the comment and the information.

[@cindywalker9787]

I take 2 apple pectin at least 1 hr prior to taking my niacin! Also, have a low fat meal. Makes all the difference in the world!

[@PrevMedHealth]

+Cindy Walker Sounds great! But take a look at the new research around low fat diet. Robert Lustig, David Ludwig, or my videos on diet and lifestyle.

[@luxurylifestyle1143]

Mike W Ellwood I

[@Cynthia...]

You can buy non flush Niacin.

[@FinTra_]

How do you take the niacin? How many times a day to get to the 2 g? Do you take TMG as well ?

[@PrevMedHealth]

Yes. And yes.

[@c4p4c1t1v3]

3:39 lol I was halfway out the door to buy some cigs. jk hah