The Most Common Allergy In The World

[@MinuteEarth]

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[@itismethatguy]

I thought this vid wouldn’t get tons of views why are they so less compared to the likes? If we are a member, does the view not count if we watch it earlier than the KZbin release?

[@Xena_bruser_willow]

Cool

[@stormfiretheog9183]

Wow first time being early :0

[@ThatCuriosity]

@@itismethatguy yeah I think so

[@itismethatguy]

@@ThatCuriosity oh that makes sense

[@Pyronaut_]

I was never told and never even considered that the reaction to Poison Ivy was an allegy, but it makes so much sense that it is.

[@pushyasaieraag2141]

@@judulbaru2607 BEGONE BOT!

[@m136dalie]

It's not, it's a delayed hypersensitivity. Allergies are immediate reactions.

[@Tsum1231]

allegy

[@nonnativenarnian]

NOT NECESSARILY I get an allergic reaction to shellfish immediately when eating, but the worst of it, the hives that come with eating crab are DELAYED by an hour or more after I stop eating.

[@LexBlueshell]

Fun fact, I’m not allergic to poison Ivy!

[@AnonymousFreakYT]

My wife has the same reaction to regular English Ivy as to poison ivy. It's super strange - and our kid didn't believe it when he was little. He thought it strange that she couldn't touch the leaf he could. He admitted as an adult that multiple times, he would wipe an English Ivy leaf on something my wife would touch to see if she would immediately break out in a rash. Of course, her reaction wasn't instant - it took a couple days. So by the time she broke out in a rash, he had forgotten that he had done it. He only made the connection as an adult. And my wife instantly had an "AHA! That explains all the random rashes I had! I always thought it was that the dog had gotten into it without my knowledge!"

[@loonloon9365]

I learned that our family had a resistance to poison ivy when I was 6 and the entire neighborhood got it when playing in the woods and I didn't. Talked to a doctor and most Native Americans are resistant. The keyword is RESISTANCE, very few people are completely immune, and with repeated exposure you will get it eventually.

[@kennybmx]

The old, it was the dog trick

[@cheaterman49]

That's a very cute story, thanks for sharing it with us :-D

[@LadyAnuB]

This isn't strange, it's your wife's immune system response cranked up to 1000 in contact with whatever molecule's produced by English ivy that's likely similar to urushiol. I have this response as well but at an 11. 😀 My response goes into high gear when ivy grows new leaves or repairs old leaves. I suspect that this same molecule is produced by redwood trees as they grow new leaves. (I can't tell if one or both cause this reaction as they are both outside my condo.)

[@justjoking5252]

1. That is evil 2. That is hilarious

[@korcommander]

You ever just roll around in poison ivy just to flex your lack of allergy?

[@FluoxetinaBelcher]

Lmfao please don't... so many idiots out there will try this

[@HisameArtwork]

@@FluoxetinaBelcher for science!! XD

[@MurdocsMinion]

You should be careful with that. It is possible to lose your immunity to the allergy, and to go straight into anaphylaxis. This is also the case with things you're "just a little" allergic to.

[@LofferLogge]

It is also the case that more exposure to poison ivy will make you more likely to develop an allergy to it. So if you want to keep your lack of allergy, it is still a good idea to avoid it when you can.

[@thany3]

I can't. I don't think it grows around these parts 😎 Or, I'm one of the 15%, but then I would still have learned about it in school or from my parents, surely...

[@SupremeLeaderKimJong-un]

On a whim, I decided to roll around in some poison ivy. It was a real rash decision.

[@bird8585]

Puns!

[@sandro5535]

Please try eating it and covering your nose with it. North Korea will thank you.

[@mrfrog0913]

We've got to subscribe to this man, make it so youtube finally recognises this man as KimJong-Un

[@HMK.]

Ba dum tss

[@shabibibrahim4892]

KimJong-Pun

[@Curtistopsidae]

Worth mentioning that the type of allergy from urushiol is different than the classic food allergy. It's a type IV hypersensitivity reaction which tends to only cause symptoms after 12+ hr vs most food allergies which are type I hypersensitivity reactions and cause symptoms within the hour

[@m136dalie]

And type IV hypersensitivity isn't considered an allergic reaction

[@Eosinophyllis]

I was thinking more about mosquito bites, which IS type I hypersensitivity

[@emmettturner9452]

Just knowing that the reaction was an allergy I had already guessed that Urushiol was the topic here. I did not realize that it was the most common allergy in the world but I did know that most people were allergic, hence one common plant-source being named “Poison Ivy.”

[@thany3]

Even so, anything that is poisonous to us, might be harmless to other animals. There might be a fine line between poisons and allergens.

[@abdullahenaya]

@@thany3 that doesn't matter. If the substance actually hurts us on its own it's poisonous, even if it's not poisonous to other animals. The line between allergens and poisons is if the immune system reacts to it when it wouldn't actually hurt us, it's an allergy

[@tranquoccuong890-its-orge]

@@thany3 in essence: poisons actually harm while allergens only trigger reaction from the immune system for no reason. in practice: only a small number of animals are resistant to poisons - the majority of them are vulnerable to poison; meanwhile each allergen only affects a few animals - while other animals are fine with it animals that seems unaffected by poisons actually have anti-toxin mechanism inside of them, so for a given poison, only a few animals are resistant to it

[@SgtSupaman]

I always knew poison ivy was safe because I was one of the few not allergic to it. Unfortunately, I seem to have developed an allergy to it in more recent years. So what I really want to know is why people can become allergic to things over time. How is our body not tricked by harmless things, but then forgets how to handle them later?

[@OrigamiMarie]

Could be that your body fought off something dangerous and similar to poison ivy, and put those antigens in the bank, so now it gets them out when it sees poison ivy?

[@Fhantomania]

Or Maybe because Magicc

[@haloharry97]

It can be the other way around too.

[@BoyProdigyX]

It was the same for me! As a kid I could roll around in the stuff. Now after a little yard work without gloves, I could cut off my hands the itch is so bad haha

[@NYKevin100]

Like the video says, we don't really know for sure. The immune system is really complicated and has a lot of moving parts. We do know that the immune response can be modified through vaccination, but we were only able to figure that out because the immune system was already modifying itself in response to real infections (a vaccine is essentially a "fake" infection).

[@ABCD-rm5vo]

Fun fact, urushiol can also be found in the skin of mango and the shells of pistachios and cashews.

[@bird8585]

Do people get allergies from those too?

[@riverfortune1990]

@@bird8585 Def yes. Bought my first mango and liked it so much I used my teeth to scrape as much fruit as I could off the peel. Rash all around my mouth the next day. 😓

[@theamazingsolt]

I pretty much need to actively avoid cashews and pistachios for this reason. Never had an issue with mango tough 🥭 🤔

[@ABCD-rm5vo]

@@bird8585 Dermatologically, yes. Contact dermatitis is relatively common in these foods when peeling or shelling.

[@sackboy1665]

@@bird8585 My mom does

[@sciencenerd7639]

The summer before kindergarten I had a real bad interaction with poison oak. Later at school, when asked about allergies, I told kids that "I'm allergic to poison oak". Other kids said, no, you're dumb, that is not an allergy because everyone reacts to poison oak. Today I found out that I was right all along!

[@Abloxfruitsyoutuber]

meet up with those people show them this video i wonder if they would remember

[@AverytheCubanAmerican]

When poison ivy isn't actually poisonous at all: *So that was a F'ing lie*

[@Psychol-Snooper]

Yeah, well the sabre tooth tiger... was not a tiger! Arabic numerals... came from India! Strawberries... not berries! Bananas however are berries, so... that evens it all out.

[@OhhCrapGuy]

@@Psychol-Snooper Strawberries aren't berries?! That's bananas!

[@christopherfeatherley]

Language helps mold our opinion towards things, often saving us, too. By calling it "poison" ivy, it probably helps deter most people from it. I know it has for me

[@Psychol-Snooper]

@@christopherfeatherley Allergy ivy would not have been a very good name given the word has only been in use since the 1900s.

[@Psychol-Snooper]

@@OhhCrapGuy It's also not an ivy!

[@princetandukar9290]

I love how pickachu is eating poison ivy 2:11

[@randomperson8663]

Yeah it's so cute! 😄

[@eglol]

I'm wearing Pikachu merch rn and loved seeing it in this video

[@emperium108]

Huh, I always assumed everyone would be adversely affected by poison ivy. Interesting to know it has no effect on some people.

[@caesar7734]

I never came into contact with it, yet

[@ConstantChaos1]

I used to grow it as a house plant (I lived in a bad neighborhood and since I don't react it seemed the logical thing to do)

[@bakrobertjohnston4889]

The lucky ones

[@RoccosVideos]

I’ve never had a reaction to it but have come into contact with it. I don’t test my luck though. It’s not something I’d do intentionally.

[@alsaunders7805]

I'm one of them, I used to pick it and chase my cousins with it. 🌿🤔🤓🍻

[@yotammor9542]

I am happy that i understand allergys now

[@Prelmable]

I'm sad that you don't know how to spell allergies correctly.

[@vallauritz311]

You don’t, this was horribly explained

[@scaboodle]

This video is a little misleading. At 1:22 you say this is the same phenomenon as other allergies. This isn't true as other allergies are IgE mediated (i.e. caused by antibodies and generally only in reaction to proteins!) and known as type I hypersensitivity. The process you have described for urushiol is a type IV hypersensitivity. Which is arguably not an allergy at all!

[@translucent.icicle]

After reading a lot of comments comparing "allergy" to poison ivy to true allergens, I agree it's misleading.

[@ThatCatLover504]

Urushiol affects more adults then children, because most people who are born without an allergie for urushiol develop it as they get older.

[@Darknimbus3]

Actually urushiol in high quantities, such as found in the cashew shell (cashew is in the poison ivy family btw), can be very toxic. It’s why you never see cashews with the shell on in the market, and why “raw cashews” aren’t actually raw (in the culinary sense).

[@Owen_loves_Butters]

Well literally everything can be toxic

[@exosproudmamabear558]

It is about the amount even water can be poisonous if you drink enough.

[@johnsteinat5213]

I wonder if there could be a related benefit that we would lose if we lost that allergy. If it only affects the primates most closely related to us and the rate is so high, it seems like that's only possible if not having the allergy was detramental to the point of almost destroying the gene. Or maybe, because poison ivy grows in North America and Humans evolved in Africa, it's just coincidence, like lacking the ability to make vitamin C

[@HisameArtwork]

some primates have a higher resistance aids, malaria and flu. the vid did say it's similar to tuberculosis and the candida fungus which lives on human skin. Maybe those two disease would be a bigger issue if we didn't overreact to their presence? Tuberculosis had a 12% death rate, ebola can have up to 92%. Maybe tuberculosis could have been higher?

[@MrBlack0950]

My guess is its a coincidental result of genetic bottlenecking. The allergy mutation was part of a small set og genes found in a reduced population, probably early on in primate evolution, and just stuck around. It might have a benefit, but it could just as likely be a quirk of evolution.

[@Fritzafella]

My intuition is its just an accident. The reaction is unlikely to result in being removed from a gene pool and thus wouldn't get stripped away over time. Though completely removing the ability to detect the chemical would have a negetive effect on our imminue system as then a few actually problamatic things could get flagged as OK after being mistaken as the harmless chemical.

[@andresv.8880]

Apparently native Americans are resistant to the allergic reaction so it may just have evolved because it was a foreign substance to the rest of the world

[@IHateUniqueUsernames]

It could be one of those things that we simply did not select against because it is of no consequence if we do or not, in the greater scheme of things. There's no selection pressure for the immune system to uniquely identify this one molecule as an exception to the way the body detects and defend against actual threats.

[@cinnamonsugarcourtney6073]

I'm not allergic to urushiol. :3 I've never had an outbreak due to it... but my brother and little sister are very allergic to it. I know because I was leading a walk with my sister and she walked after me and by the time our walk was over she had broken out due to poison ivy, but even though I was wearing shorter pants and things nothing happened to me. We were going the same path and she was right behind me, not next to or anything.

[@JesusMartinez-rr2ry]

I chuckled when you also included Bigfoot as one of humans' close relatives who are also allergic to the urushiol in "poison" ivy.

[@mrnice4434]

Good to know if a Bigfoot attacks you just throw some poison Ivy at him/her

[@hebl47]

Well, I haven't met a single Bigfoot who wasn't alergic to poison ivy, so I think it makes sense they included it.

[@hannya6552]

@@mrnice4434 thank you for respecting big foot's gender

[@garethbaus5471]

Well if bigfoot were real it would probably have been in north America far longer than even the native Americans (who are already less likely to be sensitive) so bigfoot would probably be immune.

[@no1uno388]

@@mrnice4434 have a word for you "they" amazing isnt it?

[@handsomeman-child8751]

I think I remember MythBusters doing an episode about poison ivy cures but almost the entire team were either immune or dangerously allergic.

[@iceman101101101]

Fun fact: that molecule is also found in the skin of mangoes. Found out the hard way I'm allergic to my favorite fruit🙃

[@SgtSupaman]

I can confirm this is true. Do not peel mangoes fresh off the tree with your teeth. It makes for a few very bad days afterwards....

[@Ikajo]

You should be able to eat them peeled though. My sister can't eat mango from the skin but she can if the skin is removed

[@iceman101101101]

@@Ikajo I've heard this too and makes logical sense. I was just traumatized with my experience so I've sworn off of them. Not taking any chances ha. Had hives all over my face right when I started a new job in a hospital lol Tons of scared faces followed by profusely apologizing and explaining contrary to looks, I dont have some horrible disease lol

[@Ikajo]

@@iceman101101101 Food trauma is real, so I get it. I discovered less than two years ago I'm very likely allergic to sweet melons, like honeydew. Which is rather annoying since I really like green honeydew melon. But it did certainly explain a lot.

[@SgtSupaman]

@@iceman101101101 , it's understandable that it would make you hesitant (I wound up wearing a bandana across my face to cover up the nastiness; and this was long before Covid19, so covering my face was an obviously weird thing back then), but I will eat fully peeled mangoes with no problems (only after I understood that it was the peel that was the problem). Hopefully, you can get back to it, because mangoes are too good to be missing out on.

[@cheaterman49]

I'm surprised you didn't mention it (so maybe it's wrong?) but I thought the itchy reaction we get from mosquito bites are also essentially an allergic reaction to the anti-coagulant substances in their saliva? Thanks for the video :-)

[@Soken50]

I assumed the itchiness was from pathogens carried by the mosquito when biting and the immune system flaring up once the anesthetic wore off

[@erikkarlson5902]

It is an allergic reaction, I know because I am not allergic (:

[@cheaterman49]

@@erikkarlson5902 Oh so your body literally doesn't react to mosquito bites? That is pretty cool!

[@erikkarlson5902]

@@cheaterman49 yeah, no red at all, no bump either. I literally can't even tell where they bit me once I forget. I read in a book once that about 1/10,000 of us aren't allergic to mosquitos, and I just happen to be one of those.

[@jasonreed7522]

The reaction to mosquito bites (and similar) is caused by the molecule Histamine, which is an immune system "hormone?" That triggers inflammation and itchyness, so many alergens trigger it as well as actual dangers. I would classify the reaction to mosquito anticoagulent spit to be a justified reaction and not an alergy based on the fact that insect bites are not harmless and even if the anticoagulant itself isn't a danger all the pathogens mosquitoes famously carry are (Malaria, dengue fever, west nile, ect). So you do want to be aware that you were bitten by them and react to it, even if you are from an area where these diseases are not common. I remember seeing a video on how it would take 10,000 bites daily to become and maintain immunity to their spit (desensitized) and they then immediately explained why doing so would be a terrible idea (beyond the insane daily bites) mostly being similar to how having 0 pain receptors is problematic, you wont know when you get hurt.

[@cruros9084]

Ironically just learned about this type VI hypersensitivity in my immunology class a few weeks ago.

[@johndoe-fd7rd]

Next time doctor askes if I have any allergies, "no" will not be my answer.

[@allthegoodthings707]

That was very interesting. I am now wondering why we can develop allergies to things. If we have come into contact with something that our body already knew didn't hurt it, how does further exposure teach it that it is bad?

[@7W33K]

It's called sensitization. If your immune system finds something it doesn't recognize and decides that its bad, but that thing is no longer around by the time you immune system has developed antibodies, it will only react to it the next time you encounter that thing. Somewhat oversimplified, but you get my point.

[@PramkLuna]

Molecule not attached to you: lands on skin Urushiol: And I took that personally

[@kokiriboy99]

Hi, so, sure, it's an "allergy" in the sense that it's a hypersensitivity reaction. But this is a delayed-type/CD4+-mediated/type IV hypersensitivity and it differs a lot from the IgE-mediated/type I hypersensitivities we usually call "allergies," like the reactions to peanuts and bees and pollen and cats, including the ones that lead to anaphylactic shock. Your video explains how this type IV hypersensitivity plays out, but you mislead your viewers into thinking this is also the mechanism for type I reactions. It is not.

[@translucent.icicle]

I'm glad someone else noticed

[@jasonreed7522]

As someone for whom this topic is not my field (electrical engineering), my general understanding is that an "alergy" is the immune system messing up and attacking harmless FORIEGN antigens and that autoimmune diseases are the immune system messing up and attacking YOUR OWN antigens. I understand that the immune system is more complicated than words can state so obviously my definitions are lacking a lot of nuance. However, i also don't expect the general public to understand the nuance of Maxwell's equations and how they can be used to descibe any EM field/device/system. Sometimes just knowing that sticking a fork in an outlet can kill you is sufficient. My point is complaining about a 3min video not differentiating between 2 very specific chemical event chain types classified as type 1 and type 4 hypersensitivities being a true "alergy" or not when the point is that its your immune system hurting you and not the compound itself (alergy vs toxin), is a little nitpicky.

[@m136dalie]

Allergies only apply to type I hypersensitivity, type IV reactions are not considered allergies so the video is wrong.

[@m136dalie]

@@jasonreed7522 It's not nitpicky it's a fact that type IV reactions aren't considered allergies. Otherwise host vs graft disease would be considered an allergic reaction, something it very clearly isn't since it can take months to kick in. Same thing with type I diabetes, which is also the same mechanism.

[@bosstowndynamics5488]

​@@m136dalieI know this comment is old, but it really bothers me when I see someone who is so confidently, arrogantly, yet completely, wrong. Actual healthcare resources do not distinguish between "allergy" and "type IV hypersensitivity" because "allergy" is a longstanding description that in modern usage has come to refer mostly to immune system mediated reactions to what would otherwise be harmless exposures. Some resources I could find even referred to the classification scheme that type IV is a type of as the classification of types *of allergy*. The fact that many of the most common forms of allergy people discuss day to day are caused by type I reactions does not in any way somehow make common type IV mediated allergies like contact dermatitis and zinc allergies not count, any reasonable person, including pretty much any specialist in the field, would call the latter allergies.

[@mihaleben6051]

1:54 man i touched it SEVERAL times in my life. Its not itchy. This thing feels like napaln

[@OzzieBo]

I didn’t know my body had a whole law enforcement system with handcuffs and fingerprint databases

[@GABBER-w3m]

One time, i were checking to see if leaves were nettles and once i saw a poison ivy and decided to try it. I was completely ok!

[@Alpha13Wolf]

There’s also the fact that your first encounter with the stuff won’t result in any symptoms at all. Then, any encounter afterward will. Also there really isn’t an immunity to it, it’s just some haven’t experienced their first sensitizing encounter with it, as well as those who have a very mild response to it that remedies itself quickly; before you even notice it. Unlike many allergies, stings excluded, it’s a persistent, lifelong, allergy that does not decrease with repeated exposure. Bee stings are the only allergy that worsens with repeated exposure.

[@SqueamishNerd]

Latex allergy also worsens with repeated exposure.

[@RabbitNeckyBecky]

*goes outside and touches poison ivy to see if I'm allergic*

[@joshualedbetter879]

This video has given me the intrusive thought of touching poison ivy to see if I'm allergic. It's worsened by the fact there is some in my backyard.

[@deliriouscheeto]

Wait. So every time someone told me to take extra care while washing my hands after touching poison ivy, it was just kind of useless?

[@OkohJindu]

I wasn't aware pikachu isn't allergic to poison ivy😂

[@RevYars]

Wow! Amazing how you can learn a number of new things like this in less than 3 minutes. I would never have known! Although as an Aussie I'm not sure if I've ever encountered poison ivy.

[@TheTerranInformed]

I had no idea some people weren’t allergic to poison ivy and oak! Really cool video!

[@coolbojy]

I dont know about this video. One of the animals you depticed to happily eat urushiol does seem to make a lot of sneezing sounds. Lots of red rash on their cheeks, too.

[@SirBucketing]

What about mosquito saliva? Is that more or less common?

[@MyysticYT]

I Never new that people get rashes from just touching poison ivy. How rare is it to not be allergic in Europe?

[@9SMTM6]

Would you consider making a video about the Syrinx in birds, why we think they developed it, etc? It is the primary voice box of birds, more important for their sounds than the larynx that both we and birds have.

[@ThisIsYou36]

I don't know if I'm allergic to poison ivy or not, should I test it out?

[@arooobine]

I'm as allergic as anyone else. One time in high school I weed whacked through a thick patch of it and got chopped leaves all over my legs. I ran to the shed and bathed my legs in gasoline. It did the trick! No rash.

[@Pineapply_Queen]

I remember a mythbusters episode that wanted to test if vodka worked as a poison oak cure. The premise was simple: Expose someone to poison ivy, treat one area with commercial cream, one with vodka, and one with nothing as a control. Took them six people, three of whom were allergic in the past, before someone finally got a reaction.

[@jasonreed7522]

I remember that, it must have felt like such a strange coincidence/ very "unlucky" that it took so many trys just to find someone actually allergic to a famous "no touchy" plant.

[@Pineapply_Queen]

@@jasonreed7522 That seemed to be a common theme in the show; if a plan was simple on paper, it was never so simple in practice.

[@jasonreed7522]

@@Pineapply_Queen that was definitely the norm on that show, and true to how real experimental science goes. But atleast a few myths went fairly smoothly like the water heater rocket myth (actual hazzard, dont defeat the safeties of your appliances) or the florescent nasal drip dinner party with blacklight reveal (part of the flu special episode, also very concerning to germaphobes)

[@aholesahole]

I didn't used to be allergic to poison ivy, now I get reactions every time I work in the yard. It's insane.

[@MyysticYT]

Where can you find poison ivy?

[@user-ml3hl6vr4t]

I can grasp stinging nettles without issue. Found out this was strange at a family reunion vacation. I was itching from my laparoscopy hysterectomy scars itching while healing. An aunt commented that I must have gotten near the nettles by the hot electric wire fence. I walked over, grabbed a handful like I had done for years, and turned back to her. This wasn’t my problem…

[@xavierburval4128]

0:54 I don’t know why, but hearing “your body commits mass genocide” before a cheerful “it’s a super effective trick!” is way too funny

[@HyperWolf]

Being part of the 15% not allergic makes a past memory now make sense. As a kid we went on a school hiking trip and I grabbed a fistful of leaves that I’d never seen before. My classmates followed my lead and grabbed some too. We were tossing them at each other. Until one of them started complaining. Then they were all complaining. The chaperones were confused by the commotion and went to check on the kids. There I was still with a fistful of poison ivy that I tried to hand to the lady that asked me what I had in my hands. She yelled and dropped the leaves. I thought there had been a spider at first. I got told it was poison ivy. I was spooked and I waited for the rash, the itch. I was fine. None of the others went to school the next day. There were so few of us in class that we watched a movie instead. I always thought they must have been wrong because I didn’t get a rash like everyone else did. It is kind of funny I started the plant grabbing and I was the only one spared the painful itchiness.

[@klrcats]

I wish I was allergic to it, people make me get stuff when they lose it in the forest, for example when they kick a soccer ball in a forest I'm always the one to get it because poison ivy doesn't effect me.

[@ConstantChaos1]

I am lucky enough not to react and it has helped alot as a first responder, I've had pts in fields of the stuff and so I was the one to get them and do hands on care to keep my team safe

[@zacthebold5136]

I had reactions as a child, teen, and young adult. In the last few years though, with more frequent exposure I believe I am completely bomb-proof to urushiol. I ran a weed-eater through a mini-grove of it wearing shorts and sandals. No effect!

[@TrulySinisterz]

I never knew this, very interesting!

[@cannypride8191]

Though, why don't we have the same symptoms as an allergy when we have other diseases like the shown example tuberculosis?

[@SaheeliRai]

Maybe we have, but the Symptoms oftuberculosis itself are more severe? I sometimes get a rash when I catch a cold

[@nayhem]

Pretty hard to get poison ivy in your lungs.

[@dkhl65]

@@nayhem If you burn poison ivy and inhale the smoke, you will get it in your lungs.

[@cannypride8191]

@@nayhem Yeah, but we inhate pollen and other stuff that we can be allergic to

[@mysteriousinternetperson]

I love how you drew the dendritic cell!

[@magolor2706]

I was so close. I was SO CLOSE to having no known allergies, I was literally never sick from anything. But then hayfever gives me breathing troubles in all the warm times of the year

[@esspeetwentytwo]

no wonder i never got a rash by touching poison ivy holy crap

[@faizkroller1996]

1:37 That sigh is just the best

[@Ggdivhjkjl]

That handcuff guessing method is so unfair.

[@erikkarlson5902]

@MinuteEarth aren't mosquitos a far more common allergy? I believe over 99% of people are allergic. In fact it's so common, unless you are one of the few people who aren't allergic (like myself) you probably won't even have heard it is an allergic reaction.

[@WanderTheNomad]

You mean their saliva?

[@erikkarlson5902]

@@WanderTheNomad yes exactly. I read in a book once that it is estimated that only around 1 in 10,000 people do not have any allergic response to their saliva. Never found another figure to back that up, but I've never met anyone besides myself yet.

[@NeoRazor]

Nobody is allergic to mosquito bites. Their bites itch because their proboscis is barbed like a harpoon, so when they remove it, the barbs rip and irritate your skin on a microscopic scale. That's why the bites hurt the least if the mosquito is left undisturbed for the duration of the bite, and is allowed to carefully remove their proboscis.

[@reklessbravo2129]

I remember not being allergic to mosquitoes. That was nice

[@muse208]

@@NeoRazor I’m not finding anything online about this barbed proboscis thing causing the prolonged itch.

[@joanguimaraescastro]

Now tell me why I'm allergic to strawberries.

[@sandwich2473]

Is teargas the same then? I hear that some people are immune to that as well

[@Minty1337]

that explains my immunity to poison ivy

[@astro6512]

Wow, that makes sense! Also, my dad was immune to poison ivy, does this mean he would get tuberculosis or something more easily since his body would brush it off?

[@theawesomeracer1949]

Actually, the most common allergy is ME

[@AustinMulkaMusic]

This sounds like something that can be fixed by CRISPR?

[@CosmicAggressor]

I actually became almost entirley imune to poisin ivy in the last few years. These days the area just stiffins a bit and sometimes gets a bit red. But there is none of this nonsense with itching, swelling, and small portions of skin actually sluffing off like I used to have.

[@sadieandbean]

When I was a kid I was carrying around these sticks/leaves and my father freaked out because it was poison oak but I never had a reaction. I do have some skin allergies to different health and beauty products though.

[@ProfessorUmbreon]

I love that Pokémon are in the background of every single video.

[@ComradeCorvus]

Imagine being one of the people in that 15% that aren't allergic to poison ivy. If I was, I'd just never tell anyone about it so I can randomly freak people out by grabbing a leaf and rubbing it all over myself.

[@seatbelttruck]

If urushiol is similarly shaped to tuberculosis, maybe the allergy's so common because it was more beneficial to have a quick, strong response to anything tuberculosis-like than it was detrimental to get a rash.

[@myozeka]

I think it’s the first time I hear you doubt when making a pun, such is the delicate topic of allergic reactions

[@Candi_Clown]

I heard that the spit from a mosquito to stop our blood from clotting is also an allergic reaction when a bump shows and it itches. There are some lucky rare people who aren’t allergic to mosquitoes too.

[@ConstantChaos1]

Since the compounds in mosquito bites are actually reactive/harmful and all that its not an allergy its an immune response

[@BunnyJS]

I am not allergic to poison ivy I walk through it sometimes and people call me crazy

[@Michael_Pereira]

1:59 Lol I didn't realize Pikachu qualified as an "other animal" 😆

[@qazinoorwasi]

In my school's backyard, there was a wild bush with pinkish and green color flowers that looked like closed spherical buds. We were told we'd go blind if we touch those flowers. Nevertheless, nobody did touch them. But that's still a mystery in my head.

[@trevorbrooks7816]

I knew this from a young age cause I'm part of the 15% that don't react to poison ivy! My brother and I were playing hide and seek and accidentally crouched in a patch, his week was ruined, I was unaffected and confused

[@NoodleySnek]

great another thing to add to my long list of allergies 😭😭😭 awesome video though!!!

[@HappyGick]

I actually thought that you were going to talk about mosquito saliva. The irritation, inflammation, and itchiness that you get from a mosquito bite is actually an allergy. There are people immune to these - they're not bothered by mosquito bites (except for the actual bite since it's painful). Is it less common than urushiol?

[@mediawolf1]

Well the question would be what bad thing is our immune system mistaking urushiol for?

[@stolenshortsword]

the animated version of urushiol looks so nice and polite

[@Warrenbowser3]

So would an epipen get rid of a poison ivy rash? (I'm not allergic to anything I don't know if that's what epipens do)

[@AdeleiTeillana]

My mom, brother and I are all not allergic to poison ivy, but my sister and dad are. Once in the fourth grade I got some leaves and was rubbing them all over my arms. This boy wouldn't believe it was poison ivy so he grabbed them and did the same. He couldn't even come to school the next day, lol. On the one hand, that was mean of me, but on the other hand, I did honestly tell him it was poison ivy, he just wouldn't believe me. 🤣

[@RandomRads]

Does it mean people who aren’t allergic to peanuts are more susceptible to those diseases that uses same handcuffs?

[@PlutoTheSynth]

2:09 i LOVED that pun lmao

[@jamesbaxterfirst]

Mosquito saliva primarily causes bumps via an allergic reaction too iirc

[@alexandermcclure6185]

For some reason, only the boys in my family are allergic to it. The girls could EASILY roll around in a field of poison ivy. That's why I always need help with the poison ivy near the fence.

[@haroldinho9930]

What’s poison ivy?

[@urtiyayeah1946]

Homework:*cough* You dare challenge me foolish mortal?

[@godminnette2]

Me when I saw the thumbnail: "Poison ivy or lactose?"

[@vallauritz311]

Lactose intolerance is not an allergy

[@godminnette2]

@@vallauritz311 I honestly wasn't certain if it was considered one or not until I watched the video.

[@joyo0076]

Yay, I'm a early one Great video as always

[@theauggieboygamer9148]

After watching this video I’m wondering if I am immune to poison ivy, I’ve never had a reaction to it at all despite being exposed to poison ivy several times in my life, I just never questioned it because I would always wash down the exposed body part as soon as I could after exposure and just thought that was why I didn’t react, but what really has me wondering this is my most recent exposure to poison ivy. Usually an exposure to poison ivy for me and most others is a quick accidental brush by, but this last one was different. I was pulling weeds from some stones behind my house when I pulled out this long vine from behind the air conditioner. I thought it was interesting because it was much bigger than the other weeds I had pulled. So I showed it to my dad who was outside with me and he said it might be poison ivy, at first that didn’t sound right to me until I noticed that the leaves were in groups of 3, a telltale sign of poison ivy, oh HELL NO. I immediately dropped it on the ground and ran inside to wash my hands, my dad researched pictures of poison ivy and confirmed it was indeed poison ivy. I took off my clothes and threw them into the washing machine and immediately ran upstairs to shower. However, I never had a reaction, Mind you, I was holding it for a good minute at least, and I almost certainly got urushiol all over my hands and arms, and the amount of time it took to get to the shower was more than enough for my immune system to start freaking out. After learning about it being an allergy and a select few are immune, I was wondering if I was one of the few lucky ones.

[@nunyabusiness4904]

It’s the same reason some insect bites such as mosquitos or bed bugs cause small itchy bumps, it’s because you are allergic to them

[@legalmel]

I swore it would be mosquitoes. Isn't our reaction to mosquito bites- or more specifically, mosquito saliva- an allergic reaction?

[@KatharineOsborne]

Well I’m not sure if there is an allergy component but if you look up how they actually bite, it’s a horror show. They have five different mouth parts involved and they not only pierce the skin but rough it up into mush, so it’s pretty traumatic to the skin even if it is a small wound. Lots of bacteria are going to be involved.

[@proton8689]

For the humans not affected by the poison ivy. Is it random, like people are randomly born without the allergy? Or is there a genetic component?

[@BoyProdigyX]

That's cool! As a child, I wasn't allergic to poison ivy. I thought it was because Native Americans couldn't get it. The woods nearby were covered in the stuff some summers, yet I'd be the only one that never got a rash after playing there. Recently, now in my 30's, I cleared up my aunt's overgrown backyard from lots of poison ivy and BOY am I allergic now! I had blisters it was so bad. I get chills thinking of that itch.

[@managingbusiness141]

Thank you for another great video!

[@captainpalegg2860]

I can’t remember at all who told me this, but “Some people can roll around naked in poison ivy and be just fine, and others get a reaction just from being near it.” I have no idea where I lie on that spectrum, and I hope to never find out.

[@vinnieg6161]

the allergies I get from regular grass pollen is absolutely insane sometimes, I can't even function anymore

[@lancelouis3609]

Man, MinuteEarth's videos are not complete without the puns and the pokemons in the background 😆