Newly Diagnosed Stage 4

[@ThePCRI]

Timestamps: 0:42 What are the different stages of prostate cancer? 2:58 Does the location of lymph node metastasis affect staging? 3:58 Does the number of lymph node metastasis affect staging? 5:06 Does Gleason grade have any bearing on staging? 6:53 How do PSA levels present in those with stage IV cancer? 7:24 How many stage IV patients respond to hormone therapy? 7:52 What category of hormone therapy has the biggest impact on PSA reduction? 9:12 How should patients who are concerned about side effects approach hormone therapy? 11:03 What does stage IV prostate cancer mean for the average patients lifespan? 15:07 What non-hormone therapy treatments are advisable for stage IV? 16:51 In what context is spot radiation usually used in treatment for stage IV cancer? 18:26 What is the difference between "cure" and "remission"? 19:44 Alex's conclusions

[@davegillteam]

My psa was 700 on February 2022! I have 4 walkers and 1 wheelchairs in my garage. lol. Then I stated Xtandi and Lupron, my psa is 0.1 right now!! I lift weights 4 to 5 times a week week. My energy is 100x. I sleep 7-8 hrs. I stopped eating, had a little meat anyway. I make and drink 40 ounces of juice everyday!!! I was weighing 90 Lbs on February 2023. Now I’m at 140 Lbs! Amen to my God JESUS! And you guys, I’ve been listening to your videos for 2 years and really kept my mind positive!!! Thank you for all of your help!🙏🙏🙏

[@MySteamChannel]

I have stage 4 prostate since 2 years ago...hormone, fasting & diet are my go to's for now...best wishes to everyone from Australia.

[@Johnadele28]

You're doing great, add Ivermectin and Fenbendazole protocols for even a better outcome.

[@raydecampos7327]

PCRI, I can’t thank you enough for your informative videos and support. I was diagnosed with stage four cancer at age 60 and now at age 64 after radiation and (Lupron) hormone therapy I am basically cancer free. I want to stress to others in my position and at my age that throughout their treatment they need to work out with weights and stay as active as possible. I had some complications early on and was not able to, and I subsequently paid the price. Also talk to your radiation specialist’s about radiating your nipples so that your breasts don’t grow. I now have to work extra hard to try to get my body back to where it should be. Again, thank you to PCRI for all you do. Couldn’t have done this without you. I still watch your videos as part of my ongoing recovery process. You are an invaluable gift! 💜

[@christined2495]

My husband was diagnosed stage 4 with spread to lymph nodes by the prostate 6 months ago, he is on hormones ,and just finished 44 days of radiation, his PSA is 0.1 He feels fantastic, has no more fatigue, a few hot flashes but that’s the only side effects . So glad his treatment is over and Blessed he is feeling so well This channel and the Good Doctor has been so helpful and informative when he was first diagnosed, we were able to weed through two not so good specialist , and found a wonderful hospital where he received 100% the best care

[@j.polishboy4871]

Stage 4 since 4/23 w/ a 44 psa. Six treatments of Pluvicto & Hormone therapy have been my treatments to date. My psa has been holding steady at 0.02. I feel great. Living life on my terms. God is good!

[@dryhumour11]

Can you detail where you got the treatment - Pluvicto & Hormone therapy thanks

[@j.polishboy4871]

Froedtert hospital in Milwaukee WI. The Pluvicto was part of a trial. It is FDA approved presently as a drug of last resort. The trial i was on wanted to see what happens when you give it to newly diagnosed metastatic prostate cancer patients who have had no previous cancer treatments. Best of luck to you brother.

[@hatemfarhat5489]

I have stage 4 prostate cancer since 2021..... second generation Hermon & fasting, Mediterranean goody ( diet. ) are the same as you my , also to go for now . I'm blessed. Best wishes from Lebanon.

[@indydude3367]

1806 PSA in March 2023. Yes 1806. Following ARASENS protocol. Today, PSA is .046 and I feel fantastic. Not out of the woods yet though.

[@CancerTherapy]

We find solutions! Guy Tenenbaum, Stage 4 cancer Survivor for 6 years.

[@daveh893]

As always, your comments are very helpful. I have been relying on hormone treatments for 5 years and I respond very well to them. My urologist wants me to go for radiation treatments but I don't see the need since I have responded so well. I am also concerned about the side effects of the radiation.

[@ronoster2]

That is interesting. I have had several radiation treatments over 12-14 years and never had any side effects-until this week. I had a second spot radiation on a lymph node two days ago and have a little pain at the location-not bad but it's there. I have three more treatments and I am going to ask my doctor if that is normal and how fast will I recover. I have resisted hormone therapy because I want to avoid the side effects. I am 75 and fairly active: I swim, ride mountain bikes, and coach wrestling (on the mat) as well as walk a mile or two each morning. I have a friend who got Lupron treatment and is suffering from hot flashes still after a year. In 2011 I had 44 expernal radiation treatments over 8 or 9 week period. No side effects at all. About two years ago I had two brachia therapy HDR radiation treatments. I little more invasive and a little short term pain but no side effects. Based on my experience, I would not worry about side effects from radiation but talk to the doc for more info. Good luck, pal.

[@PatB415]

My Husband diagnosed @ 77: Stage 3, Gleason 8 & 9. Each round of Hormone therapy bought him 15 mos of life extension each time. At 83, Stage 4, he failed ChemoTaxotere at # 5 of 6 treatments. Gene tested result: BRCA. Received 5 treatments Proton Radiation + 5 mos Talzenna Parp Inhibitor, which drove his Hemoglobin down to a critical 6. The 2 pts blood transfusion drove his PSA up (continuously doubling up to 160's). 2nd round of Talzenna (lower dose), but same result. With another 2 pts blood transfusion, he's back on Chemo (every 3 wks: Jevtana + Carboplatin, and 5 days: Proton Radiation again). He's now 84 & while fatigued, Dr says he's responding well. If this doesn't work, he'll progress to Pluvicto. Trust the process, exercise, diet. I also now pray to a cancer Saint.....Saint Peragrine ! Thanks Dr. Schoz & Alex for keeping us well informed & prepared for the future!

[@tomswoverland]

5 years with stage 4 Gleason 8 no long term remission but still going on. It goes away but as of yet comes back right away. Tired of the continuous treatments. Had 4 spots just targeted in September waiting for results in December not looking forward to more treatments since I have had most. Don’t know if I want to do chemo again and I have had a total of 50 radiation treatments a few targeted treatments isn’t bad but I started off with 44 treatments not much fun. Dr Kwon has been my Dr after I finished the 44. Good luck to all.

[@edg531]

Hang in there, Tom. Wishing only the best for you!

[@basileglof3775]

Respect and thanks to the team at PCRI. I also recommend a book by Dr.Leonard Coldwell , it's called the " The only answer to cancer." You can find many usefull tips and what supplements you should boost your body with. But tankyou to Alex, she has so much empathy for us suffering men.

[@ThePCRI]

Advanced Prostate Cancer Presentation By Dr. Eugene Kwon: kzbin.info/aero/PLHj3V3RB2V-gMK9TMMGa-OwKp9K4D7TEB

[@ThePCRI]

Bone Metastases & Spot Radiation For ProstateCancer | Mark Scholz, MD: kzbin.info/www/bejne/ZmKXgGd8bpxkq5I

[@Wayne-yq4xl]

A really relevant and superb video for my stage 4 . Thanks

[@ThePCRI]

Combination Therapy: Chemo, Hormone Therapy, and Radiation For Advanced Metastatic | Mark Scholz, MD: kzbin.info/www/bejne/jKPHipeto9Ken7c

[@ThePCRI]

Treating Side Effects of Hormone Therapy | Mark Scholz, MD: kzbin.info/www/bejne/e5Ddi2CifJuYm7s

[@jeetujeet27]

Unfortunately my father prostate cancer is very agressive. It compressed his spinal cord and he is now paralysed below waste ...it's very cruel disease, all of this happened in 8 months only. Prayers to everyone who is fighting 🙏

[@ACTIVEPAIR]

Another superb video, thanks 🙏🏽

[@mmazkoory3628]

Thanks again Dr Mark and Alex for this very wonderful informative episode about prostate cancer and its therapies.

[@jeanetteshaw5177]

Thankyou for this very very informative video which answered many of my questions.

[@ThePCRI]

Genetic and Germline Testing + Q&A | Brian Helfand, MD: kzbin.info/www/bejne/oWXPiKWGl7NpnLc

[@carladerenzy3674]

Enlightening discussion. I was/am Stage 4 metastatic. PSA was 525. Now 0.1. I'm on Nubeqa and Orgovyx now for 19 months. No new cancer. Had 6 Lutetium infusions. What's your educated view on the possibility of my going off these ADT's and continuing (forever) with my strict dieting exercise? I have built muscle, body fat is 8.7, and all blood work is good. The drugs I'm on are costly also. I'm feeling better than ever, btw.

[@davidf9630]

I have a question… I have stage four prostate cancer and HAD over 100 metastases on my skeleton… as well as my lymph nodes…I have been on a ketogenic diet for 18 months now and I have less than 10 metastases and my lymph nodes are clear of cancer. My question is how impactful is my diet in regards to my cancer? I don’t seem to get a straight answer from anyone in the medical field, except for the occasional diet MAY help but there is no clinical evidence.

[@kristinag1610]

I hope someone replies to you on this. Diet ? Fasting?

[@nelsonoliva2119]

What treatment have you received so far? or are you saying keto has helped reduce your cancer volume? Also do you eat red meat , pork etc as part of your keto diet?

[@Mark_Lacey]

David, I'm in the same boat, Stage 4, same extensive mets. Over 12 months most of my bone mets have gone and I've gone from palliative SoC to spot radiation on my prostate and pelvic lymph nodes. I was keto for 9 months before diagnosis so pretty sure that a keto diet won't on it's own prevent PC. I am still keto but I am a great believer in combining SoC with metabolic therapy and have been researching and implementing some of Tom Seyfried's protocols. Got my final spot treatment #28 today. Good luck mate.

[@basileglof3775]

@@davidf9630 Get a book of Dr. Coldwell, he has answers how to fight all Cancers. American Oncologist worked in Berlin Germany. He heals patients by over 90%.

[@peterschenk2352]

Have you been on ADT treatment while on the ketogenic diet? I also have stage 4 and using diet and fasting among other things but struggle getting my ketones up and wondering if my lupron injections are impacting my ketones.

[@shus5787]

Good interview

[@fredlevinssr3021]

I seen my doctor and he wants to schedule me for an imaging appointment. My PSA dropped from .5 to .3. He thought it would be lower. He thinks there might be a piece of my prostate that was left behind after my surgery. I didn’t want to wait until another PSA test because if there’s any part of my prostate remaining I want it taken care of as soon as possible. I understand that if that’s the case the possibility of radiation treatments would be the next possible step. Is it possible to have another surgery to remove what’s left or would radiation treatments be the best option? I look forward to seeing each of your presentations!

[@andrewharms2460]

Please do a talk about Titan penile implant.

[@alexandrealmeida6278]

I was recently diagnosed with pc gleason 4+5 with 5 positive pelvic lymph nodes, they say not curable, is that correct? Nothing else, only 5 lymph nodes.

[@1958zed]

Maybe I'm the exception that makes the rule, but every time you so confidently say "We know that Gleason 6 does not metastasize," (5:09), I cringe. I was diagnosed 14 years ago yesterday at age 52, and the first sign that something was amiss was a palpable mass felt on my prostate. My PSA was 5.0 ng/mL and 11 of 20 cores on my biopsy came back as positive. I was given a Gleason of 3+3. Under your guidelines, I would have been a candidate for active surveillance with a Gleason 6, but I went ahead and had a radical prostatectomy. The pathological Gleason was upgraded to 3+4. Was the biopsy Gleason incorrect? Who knows. My post-surgery PSA remained undetectable for 54 months, and then it came back but it rose so slowly that we watched it. It took 6 years to get to 0.2 ng/nL. At that point, we opted for salvage radiation therapy (SRT) with concurrent androgen deprivation therapy (ADT; six month dose of Eligard). The SRT failed and now, 27 months after the end of SRT, my PSA is up to 0.69 ng/mL, tripling in the last year. I meet with my team Thursday to discuss what's next. BTW, two PSMA PET scans taken at PSAs of 0.22 (before SRT) and 0.37 (after SRT) were inconclusive. Again, I cringe when you say it doesn't metastasize at Gleason 6, because 14 years later after RP and SRT, my PSA is very much alive, well, and increasing. Maybe one more PSMA PET scan at my current level will show that my original Gleason 6 has, in fact, metastasized.

[@alliaj1]

Your biopsy failed ...i have two pathologic biopsy opinions: one have more "3", second have more "4"😊..After RALP 4:3 (4-70%).

[@Mari-su3nv]

He is referring to a true 3+3 . Unfortunately many biopsies that suggest that level actually includes some 4 .

[@donnavanclarke5453]

What you have is a biochemical recurrence, that is not the same as a metastasis (spread to different parts of the body).

[@1958zed]

@@donnavanclarke5453 One of the frustrating things about prostate cancer is how squishy terms and definitions can be. The National Cancer Institute defines metastasis as, "The spread of cancer cells from the place where they first formed to another part of the body." My prostate-the original location of the cancer-has been gone from my body for nearly 14 years, but we know that the cancer remains and continues to grow. In the strictest interpretation of that definition, you would have to conclude that it's metastatic. But, you're right. In the prostate cancer world, they like to use BCR as sort of a transitionary category between the original cancer and metastasis. "Yeah, your prostate is gone, but the cancer is likely still somewhere in your pelvis, and that's close enough to where the prostate used to be so we won't call it metastatic." I even saw a medical oncologist say that even if it's in your lymph nodes below your navel, it's not metastatic. If it's found above the navel, it's metastatic. And, yes, the National Cancer Institute does specify that formations of new tumors elsewhere are what makes things metastatic. In BCR, we're dealing with microscopic cells who-knows-where in the body so those aren't technically "tumors." But it's still cancer. I know it's all semantics, but from my perspective as a patient, they took out the prostate where the cancer was located. The cancer is still there when it shouldn't be. It's metastatic.

[@barneyclancy4312]

If u don’t have insurance, what are the chances of u getting treated

[@lyssamichellem]

Call Orgovyx and see if they will sponsor you with a scholarship by mailing you free prescription. They did it for my dad! Totally free!!

[@barneyclancy4312]

@ thank u