Those diuretics actually trick the kidney into retaining more sodium and water! I learned about this in med school. Your kidneys filters blood and this filtrate goes trough many U shaped tubes(simplified). Mark's problem is in the late part of the "tube system", normally where most of the water is retained in the presence of a hormone called vasopressin. Mark HAS this hormone, but the tubes DON'T respond to it due to genetic defect. There is a sensor for how salty your urine is right after the place where this diuretic works. Since the diuretic blocks sodium retention more of it is left in the tubes. The sensor signals more salt+water has to be retained from the tubes. When a normal person takes this diuretic the effect is minor relative to the amount of the urine lost.
@danielgleason11262 күн бұрын
I have to take a hormone replacement for my condition to get under control.
@markostipcevic2 күн бұрын
@danielgleason1126 I guess you have central diabetes insipidus, where vasopressin is not being produced, unlike Mark's primary kidney problem.
@yacinebek17115 ай бұрын
I hope this guy finds peace in life ❤
@andreavisus3 ай бұрын
Me to
@bhargava075 ай бұрын
Bro I don't even drink 3 litre a day
@Techno-3875 ай бұрын
Same
@NoName-cx3gk5 ай бұрын
With food together it is 3 litre, because food contains also water
@villhelm4 ай бұрын
I only eat jerky and freeze dried food…
@s7z7gy4 ай бұрын
@@villhelmMaybe you should try opening up your diet?
@Nugget_prime4 ай бұрын
I don't drink even a litre per day
@brandiepop5 ай бұрын
i have a sweating disorder where i sweat anytime i move at all and i drink around 6-8 litres a day of water, i cannot imagine drinking over double that.
@h0sto_5 ай бұрын
same
@LelandballBall4 ай бұрын
Dang hope yall are fine❤
@xademirr4 ай бұрын
i have hyperhydrosis i just sweat more on my hands and feet i cant imagine having that disorder even this is hard to me hope ur doing fine man ❤
@thesovietonion46712 ай бұрын
Dang, I assume you take a lot of electrolytes?
@keltonleung5 ай бұрын
Bro really say “drink your water”
@RmvVR4 ай бұрын
Cringe comment
@MDobri-sy1ce5 ай бұрын
I watched the documentary on this guy a couple years ago now. I hope his condition has improved since then!
@ArchiWorldRuS5 ай бұрын
That's why marathoners don't drink pure water mostly. They drink special electrolytes that can maintain their sodium levels without putting too much pressure on their kidneys
@LeanAndMean445 ай бұрын
Or any athlete for that matter.
@user-strength105 ай бұрын
Weekly sunday dose of Browney haha.... "don't forget to hydrate" (alright, where's the light beer at? 😎🍺)
@ghfhgtrhdx5 ай бұрын
Drinking 5X times more than me. God damn
@alienbuddy93795 ай бұрын
udrink 4 litres???
@kaasjemosterd60115 ай бұрын
He drinks 10 times more than me 😮😮😮😮
@Sirbobsef5 ай бұрын
I’m drinking water while watching this
@cohen-YT5 ай бұрын
7:17 nobody’s gonna talk about that
@axolotlwaddles4 ай бұрын
what?
@rmdg56414 ай бұрын
Fr
@Arkan7554 ай бұрын
Bro now IM scared of water💀
@arttukilpi8195 ай бұрын
I actually have a similar condition, its also called diabeted insipidus, but luckily my issue is that i dont produce the hormone which his kidneys cant process. So if i take it in pills, i can live relatively normally.
@Noob2Amazing5 ай бұрын
Why is he happy that the guy in the thumbnail has to drink 20 liters a day 💀
@Jaychairoek-x2t5 ай бұрын
bro was drinking from a bowl at one point lol
@high-captain-BaLrog5 ай бұрын
its normal to drink around 4 Litres here in the 47 °C weather but 5 times more than me EVERY day is impossible.
@shino88545 ай бұрын
47C where the hell you live brah, in the Sahara?
@high-captain-BaLrog5 ай бұрын
@@shino8854 north-west iNDiA.
@diptanshusingh14215 ай бұрын
Are Bhai garmi ney halat khrb kr rhka hai
@mccrackerstacker5 ай бұрын
Keep praying folks the lord is strong Amen
@DV-14.7.245 ай бұрын
Imagine him being an alcoholic💀
@toystoryplays22675 ай бұрын
Bro really pauses every 10 seconds then really switches to a whole other video 💀
@jincyroby26025 ай бұрын
Me in the corner of my room disappointed that i can't even drink 1 and a half liters a day
@jerrebrasfield42314 ай бұрын
I find water flavor additives make it easier to drink more.
@Justhim355 ай бұрын
He really is the water boy
@funnygallie78634 ай бұрын
At that point I would ask to die. 💀
@YMB1245 ай бұрын
I'm your biggest fan.
@haxfor14 ай бұрын
This man needs to find a liquid IV packet, one pack can make water 3-4x more hydrating.
@AustinClark-g5nАй бұрын
Man he is the exact opposite of hydrophobic
@glowingskydog1815 ай бұрын
Petition to make this Browney reacts 👇
@LegendaryMikeTyson4835 ай бұрын
I drink 3-5 water bottles a day
@shino88545 ай бұрын
He better have a ensuite bedroom.
@Just_think_ableYT5 ай бұрын
His bank is wining
@Jasonred79squeek4 ай бұрын
4:50 your KIDNEYS cannot process more than 1 liter per hour, so you can’t pee more than 1 liter an hour. But when you work out, you SWEAT a lot.
@CRBarchager5 ай бұрын
8:05 Not a cure. A treatment. If it was a cure he wouldn't had to take any medicine for it.
@Sarah-EmManuel5 ай бұрын
❤ LOVE your vids😊😅
@nevanashad66545 ай бұрын
Why does stan luk happy in the thumbnail
@Dino-oz4ck5 ай бұрын
it's weird because primary diabetes insipidus causes your thalamus to stop excreting ADH (anti diurtetic hormone) so to me using diuretics seems counterproductive, that being said, if it's nefrogenic problem i think diuretics can help him, but what i think is that they made a voice over mistake, and the doctor prescribed anti diuretics. that's what i think atleast
@Iretnas15 ай бұрын
i had to drink 2 cups of water after watching this video
@Hallow_call3 ай бұрын
Poor guy
@katiegillette75624 ай бұрын
I drink 9-20 cups a day. But a lot of that is electrolyte water, juice, and milk! I get electrolyte deficiency very easily if I drink plain water when I’m active, which is most of the time because I have ADHD
@ghnbtrcv86724 ай бұрын
When I was on creatine I drank like 6-7l a day and it was nightmare
@MohammedSirwanHamarahimHassan4 ай бұрын
We must thank Allah for everything he gave us! 😢
@Ashiv_Manmani5 ай бұрын
WATCHED.
@edaodu55164 ай бұрын
Emotional damage
@chrisbarry93455 ай бұрын
Use a larger container (but not too big to carry easily) and you WILL drink more. I exclusively drink from a 48 oz water bottle and it's impossible to drink under a gallon a day. I don't even track but have to be drinking 4 of them a day including like 60 oz to start the day
@mr.mikeygaming37235 ай бұрын
For me since I am a teenager hitting growth spurts while being an athlete, I don’t get really thirsty since I eat so much. I have to drink more than when I am thirsty. Doctor said 80-100 ounces a day. He recommended for me to stay closer to the 100 ounces
@jinafhsn2761Ай бұрын
Did he try liquid IV?
@Zahra786005 ай бұрын
Damnnn 2 litres a day is hard for me like that’s insane but would the water make him full?
@Adiiie__M5 ай бұрын
If i was him id open a KZbin channel and just drink water and post for the rest of my life
@oldskool64105 ай бұрын
You think it's a joke
@bear-gj7oq5 ай бұрын
i have a kidney codition i have to drink 4-6 letres but 20l is like imposible big respects
@YeetJohny-ip2tr5 ай бұрын
2:29 go there
@lavender_heart52634 ай бұрын
holy crap i feel bad for that guy
@Himi_thi5 ай бұрын
Why was I born
@moxorplayz6265 ай бұрын
Under 30 min squad
@windowsxp85795 ай бұрын
When you google, it was 3.7L of Fluid not only water
@racheltuomi86952 ай бұрын
Omgudds,thanks for this video; it just answered a question I had. I drank four Pewdiepie GFuel tall boy shaker cups(they're pretty big cups!)worth of water after a work out and was wondering why I felt drunk, I have a small kidney problem...
@UranHja5 ай бұрын
Your kidneys can remove 0.8 to 1 litres of water per hour, so theoretically you could drink 20 litres of water in a day. This assumes that you drink at an even pace, though. There are cases of fatal water intoxication where the victim has drunk seven litres in three hours or less.
@Elainyan4 ай бұрын
And here I am complaining about having to drink 4l everyday after kidney transplant
@danielgleason11262 күн бұрын
I have a version of diabetes insipidus.
@milkweedsage5 ай бұрын
I get water intoxicated on WAY less than the amount they quoted. Maybe 5L on a hot day and I'm out. I keep emergency chips in thr car.
@marionamewontwork26814 ай бұрын
I drink 4-10L daily, depending on season
@YepImBacon5 ай бұрын
Idk why but the guy looks like TommyInnit
@zkilerex96615 ай бұрын
Thats as fake as the woman who never ate for the past 27 years
@UranHja5 ай бұрын
… some people," says Hultin, noting that the kidneys can eliminate 27 to 34 ounces of water per hour, or a total of 676 to 947 ounces (20 to 28 liters) per day
@Captain-Tom.4 ай бұрын
5 1/4 gallons for people that measure properly.
@mattlars894 ай бұрын
Man he must be going through a lot of Sodium to avoid water poisoning. I´m struggling with 3 liters a day lol.
@user-ti5or4ny1e2 ай бұрын
The Problem is not the much water its water without elektrolytes. Look for example on the riders of the tour de france.
@dozenazer18115 ай бұрын
3:36 of course this is nonsense, Bielefeld does not exist in the first place
@AtermanThePatriot4 ай бұрын
He needs the carnivore diet
@tajamalrafiq36514 ай бұрын
On average day 2 glas of water, other day when I feel thirsty or do some workout, of course I take more, maybe 6-10. I actually one instance when it was really hot outside, between 40-50, holidays, I drank around 30 glass of water, of course I was sweating it out, here I'm alive.
@XhodanXeus4 ай бұрын
how does your app know how much water i need? every person is different some need more some need less. most people dont even know how much water they really need so how can your app know?
@Mark_nobody34 ай бұрын
Sometimes people just want to cry because there are other humans who has such a bad condition that near permanent disability
@YMB1245 ай бұрын
I remember you At 250000 subscribers.🎉🎉
@meneerpeer76535 ай бұрын
mate i barely drink a litre a day
@nicolahua11505 ай бұрын
Damn, ik this is obvious but you really need to drink more water.
@meneerpeer76535 ай бұрын
yeah ik
@milkweedsage5 ай бұрын
My friends husband had this, and passed it on to their son. I would have chosen not to have kids .
@leandroonofaro82734 ай бұрын
i have that too but there is a medication called desmopressin
@Hex3d-v5y2 ай бұрын
I have a medical problem that sucks more than this one. In the lombar zone i dont have the membrane that protects the sciatic nerve and basically i have constan pain in the lower back and down the leg
@SoHoshar5 ай бұрын
1 hour gang
@milezdravkovic86564 ай бұрын
my only question is how does he have the money for all that water
@Moonblox6785 ай бұрын
i have the same dysorder and its not ez cause i stand up at night and wet my bed i had this for so long i ones passed out and it cost so much
@Moonblox6785 ай бұрын
also your throught gets really bad
@cadencam18505 ай бұрын
I will bench 135 once for every like this comment gets
@carti67524 ай бұрын
You’re about to be in the nfl combine top ranked by how much reps you’re gonna have to do
@Cheesecake........4 ай бұрын
Stop this npc comments
@cadencam18504 ай бұрын
@@carti6752 ...I'll just split this into multiple sets lool. One to two sets should be enough
@cadencam18504 ай бұрын
@@Cheesecake........ I'm not an NPC lol. I'm just bored and looking for a way to challenge myself (ope it got a few more likes time to do some more reps).
@bakerfx49684 ай бұрын
It’s ok I just report comments like this as spam. Big problem on KZbin. Probably got the idea from a bot that posted on a previous video. Or this one is a bot
@quack895 ай бұрын
I actually thought this was going to be about a condition called Sjogren's syndrome. Any viewers feel free to look this up.
@Cool_Cat_ForReal5 ай бұрын
sheesh 51 views only
@Movie.reviews-s5 ай бұрын
Dear browney change your channel name from browney shorts to browney reaction. Because you do reaction most of the time
@albiium5 ай бұрын
shut up 🙏😄
@ICSEHELPER15 ай бұрын
@@albiiumnow tell me why should he?
@albiium5 ай бұрын
@@ICSEHELPER1 for my pleasure, if you got a problem with that then you're the problem
@ICSEHELPER15 ай бұрын
@@albiium guys like you are not meant for debates because if you ever bully someone , just say the bully was for my pleasure. Wow!!
@SolarSeeker454 ай бұрын
It's probably a mineral deficiency. If you drink a LOT of water especially distilled or reverse osmosis water the more you drink the thirstier you get. The signal which tells you that you've had enough water depends on minerals in order to function. Most likely he could resolve his condition by drinking sea water.
@Piggymightfly5 ай бұрын
I drink less than 1 liter per day i barely drink water
@delvinsano88335 ай бұрын
no way e drinks 20kgs of water per day (1 liter of water=1kg of water)
@AiMeetsHumanEmotions5 ай бұрын
reupload?
@JoshuaMutandwa5 ай бұрын
That one time you need to go to the toilet and there's no power then what happpens 🧐
@tmiller91975 ай бұрын
Why did they wait until the guy was in his 30s to try diuretics. 5 minutes in to hearing his story and it was the first thing that I thought of.
@rubenjr29135 ай бұрын
Nephrgenic diabetes insipidus
@magharninja18115 ай бұрын
I know a guy with the same condition
@1stragadozo6173 ай бұрын
This video is about a selfish man. A normal person consumes 2 litres of water a day. Multiply that by 31= 62 litres in 1 month. Now, this selfish man consumes 620 LITERS in 1 month. And there must be a way to use less water, but he's just too selfish.
@jerrebrasfield42314 ай бұрын
Catheter and sleep.
@pouyatorkiyan32585 ай бұрын
Nice 👍
@h0v3r575 ай бұрын
Ohhh so this is the disease Eddie hall has😂
@Switzgorr5 ай бұрын
dont 3 litres a week barly 500 milimtre a day, btw does ilk count becuase i drink a lot
@charlieeaken10464 ай бұрын
I have the same medical condition but I take a pill it makes my cells not hold water so the pill tells my cells what to do I guess lol and I’m not as thirsty