What is Major Depressive Disorder?

[@d.g.llamas4145]

I've had MDD since 1978. Right now it's 2020.

[@DEPARTMENTOFREDUNDANCYDEPT]

Your description paralleled my experience with depression exactly, and it was the combination of an effective therapist and appropriate medication which enabled me to return to a stable mood which has lasted over ten years now. A major stumbling block for me was finding a medication which worked, and it took a long period of trial and error to find a medication which helped me. Unfortunately, some meds made things worse and had unpleasant side effects. Careful auditing of my mood by my therapist while trying different meds is what finally helped me to find the one that was helpful. All I can say is KEEP TRYING with the help of your doctor and your therapist until you find what works for you. Medications affect everyone differently, and what works for one person may not work for someone else.

[@jackiesorrells5571]

Finding and maintaining a beneficial pharmaceutical approach is a challenge.

[@phreapersoonlijk]

Severe, and for well over 20 years...

[@kilo_charlie0226]

I’ve been told for years that I’ve had depression, since 2013. In May of 2020, my therapist and a Psychologist diagnosed me with MDD, severe and GAD, severe and Complex PTSD. I never knew that MDD differentiated from depression because of the episodes that are experienced.

[@tsbcmhc2083]

MDD having a 12 month prevalence in 7% of the U.S. population, we are talking about nearly 23 million people! That is an incredible large number. I would not have guessed that.

[@777anakin]

I have PTSD and major depressive disorder is part of it.

[@ambergriffes6122]

This is me to a T! Thank you Dr. Grande! It's been so much easier to understand my diagnosis by basically having it read to me, but i can pause and back it up all that I need 😂

[@adunn9498]

Great topic, Dr. Todd Grande: I wanted to touch on something you did not mention, often times, major depression is closely associated post heart surgery and post Thyroid surgery. It is not exactly clear what happens during the surgery but one example i know of an individual had her thyroid out and was never the same, she was now living with major depression and was told she would need meds the rest of her life, she had no previous history of depression, now living with severe hormonal imbalance that lead to depression: it did not come and go, the change in the brain can be permanent. She had no drugs involved, I also know someone else who had heart surgery same thing so its interesting to note if the individual had a major surgery prior to the onset of the depression that could bring on depression. thank you

[@kikixiong6156]

This is an integrative and informative! I like that you also express your opinions along with your explanations.

[@jacquelinethereseplunkett221]

If major stressors did occur (job, friend, moving) and family support is non-existent ...In a pandemic...what should I do?

[@rhobot75]

Check on the isolation, plus now I have developed photophobia "light sensitivity" and live controlling eye pain that will trigger migraine. Anyway, yeah, the depression is so isolating, but what I want to say BRAVO Dr. Grande to is YES, particularly my mother, will move away from me when my symptoms are really running me ragged but she will come closer again, even admonishing me to be safe at night, when she thinks I'm on an up. I will chalk this up to family-related factors for depression, of which the family tree has scores- that we have a dance finely tuned from generations coming down to us , plus just so many other factors like my step dad's alcoholism and we are all super Claudia Black: IT WILL NEVER HAPPEN TO ME'd but I'm also if the most "ill" the most into psychology! To refer to that book to anyone in my family is to get a Huh? I mean, I bought one for my sister but she never read it. And my brother disowned us and changed his name. People would rather get away from each other-in my nuclear family that I grew up with- than be intimate. Only again, they would not think it thru this far to say, I can't be intimate. So this is great. I'll have to find your video, Dr. Grande, on the .. ?word "itiological" I guess birth factors and environmental risk factors for major depression. My mother is an adopted child and has a Dismissive / avoidant attachment style, and I besides being depressed have an anxious disorganized / and or preoccupied attachment style. :::: And as we get older, my sister and I are pulling apart not getting closer. Anyway, good note, Doctor! Thank you! Whew.. !

[@rosewaggoner6834]

I cant talk about my feelings i physically cant just thinking about it is too much for me but i cant keep living like this i can not talk about my feelings or what’s happening what is the best course of action

[@martasouso8244]

Dr todd grande can you please make a video on cptsd and how to overcome it, and chil abuse and how that affects you life as adults, please 🙏❤️

[@rhobot75]

A second note of nodding to the realism of a substance abuse disorder. I'm going to watch these. But not quite form the angle, and it's a interesting predicament--- and which comes first, drug use or depression- I stated smoking cigarettes when I was 13, almost 14. I smoked for 34 years before going cold turkey 7.5 years ago, Today is day 2,745 MOF. And as a teen, yes, I did a lot of coke, pot, - it was the late 70s / 80s and, as you have said elsewhere Dr. Grande, we used to "wander around" alot.. Get off the wall-mounted Kitchen phone and then go driving places, taking mushrooms and wandering the woods, or going to the beach. The point being, my brain got wired hard for nicotine and while I went on to try just about everything, I managed to not get addicted to anything else. .. Until recently however when Cannabis became legal in my town and I could go get some and.. cut to a year and a half later.. I've developed a bit of a crutch about smoking! Fart! Or stronger word! It SUCKS! It's just pot, so but also yes I have to cope with psychological dependence there too but mostly I'm talking about, lately I'm looking at all these videos wondering if my diagnosis needs a refreshing maybe to bipolar or borderline when then, for example, Dr. Grande brings up having to rule out SUBSTANCE ABUSE DISORDER. NICOTINE and Smoking are just as devastating as any other "actual drug". And I'm stuck with this, possibly. And embarassed to be all caught up having to smoke pot because my smoking fingers are going crazy! .. I can't honestly say, to a new psychiatrist or therapist, Oh hi, I think I've uncovered I'm either x or x, can we spend some months and you ask me questions? until also I've come to terms with whether symptoms of borderline I feel, including anger, or to do with my damned cigarette smoking habit and also just generally taking so many drugs and now cannabis is legal, a pandora's box for someone in my situation.

[@kathrinjohnson2582]

Thank you so much for this video! It makes perfect sense.

[@DrGrande]

You're welcome!

[@lesliepfeifer8518]

Really great video. I have mdd, long story short, I've had 2 good days in a row! I added a abilify to my med cocktail 10 days ago, maybe I Finally found the missing ingredient! I'm on 5 meds now. I've been 9n at least 10 different ones before this mix. I'm so sick of being sad and angry and missing out on life. I don't want a relapse.

[@feline501]

Did you gain weight on abilify yet? I hear that everyone gets significant amounts of weight gain.

[@JoeDirt-el2fr]

Great thorough explanation!

[@virginiamurrey9139]

Great video explaining criteria for MDD, I enjoyed listening to this and gaining a sense of more information.

[@amarub90rubino43]

I’ve been trying to figure this out for a decade.

[@TheArtemis07]

I had to look up psychomotor disturbance. It would be helpful if you defined some of these terms. Comorbidity is another one that gets a little confusing. I take it that comorbidity means that two conditions occur at the same time, but because morbid has to do with death, it sounds really dire.

[@hayleybourgault4114]

I had one episode of MDD, I hope it never comes back.Medication has helped a lot.Why do you think women suffer from it more often?

[@missrhia4325]

Was recently dx so thanks for sharing its very informative

[@yosrakhedher6894]

thank you a lot doctor grande for this amazing video you are such a great doctor

[@johnharrisjr2808]

Great video! This is a good explanation of Major Depressive Disorder

[@wandamixon5360]

I appreciate that you clarify recovery, relapse & recurrence of MDD in addition to stating the characteristics that you have professionally observed.

[@janicedixon2051]

Me too! His explanation helped me understand the process of major depressive disorders.

[@curtistindall5951]

Me three--I was unclear uncertain about how to differentiate single episode vs recurrent.

[@jack_knife-1478]

I feel worthless im pulling my hair out literally I crying every day Iv lost all interest in everything waking up to early I am constantly thinking of ways to kill myself every day I keep shaking I don't want to live anymore. If I had a simple drink that would send me to sleep and die I would guzzle it down!! That's how bad I feel.

[@veronicabetz9452]

I find it very interesting that although females are 1.5 to 3 times more likely to be diagnosed with MDD than males, the course and treatment response is the same with males and females.

[@lrrrruleroftheplanetomicro6881]

yet men have a higher risk of suicide. maybe females are better at reporting MDD because, for societal reasons, they have better access to their emotions.

[@through.a.barrel.she.breathes]

I have been diagnosed me with MDD, GAD, Bipolar , PTSD and Complex PTSD. I never knew that MDD differentiated from depression because of the episodes that are experienced.

[@karensellers8264]

Thank you Dr. Grande. Can MDD be caused by a hormonal imbalance? I have suffered with MDD over 10 years now. Psychotherapy was not at all helpful. Zoloft has been a great treatment for me. If I miss more than 2 doses of Zoloft, a very noticeable angry mood swing occurs. Is this normal?

[@cherylcalogero3330]

Love you Dr g...

[@amarub90rubino43]

Fucking accurate asf! I have major depressive disorder and you are so good. My addiction caused it.

[@bluered5527]

Honestly I think I have this

[@Decompiling]

I'm on SSI for this and I'm only 27... i hate being this way.

[@ag2897]

Can you create a video on emotions and cognitions of MDD?

[@DrGrande]

Yes I can - I will add it to the production list. Thank you for the idea!

[@barbaramatthews4735]

Does that have anything to do with "cognitive impairment?" My psychiatrist suggested that I may have some mild impairment.

[@sunnysidecarebear]

So what do we do with the loss of energy every day? Cause i got a house to care for and i can barely get out of bed. I have MDD and GAD. Im not getting much help. They just keep giving me lexapro and its not working. It worked to a point then leveled out. I tried remeron but had a reaction. I have a life to live and if i could just go, i might would start feeling better mentally too. More excercise and actually finishing a goal. This energy level has me so down on myself for being lazy. Ive had reoccurance but dont remember it ever tanking my energy levels in the past.

[@tanyayasmin6101]

Can sleep disturbances with anything related to insomnia I have more like a chronic type of insomnia and sometimes middle sometimes paradoxical it's just overlaps one another but it is always insomnia

[@through.a.barrel.she.breathes]

I have bipolar only recently diagnosed so does that mean I don't have MDD anymore or never did???

[@ms.sturry684]

I live near Clemson South Carolina... can you recommend a good doctor near here that can help treat this disorder. I'm 60 years old and I know for a fact I need help.

[@robinsk5644]

I would encourage you my friend to ask someone very close to you (friend or family) for a suggestion concerning a doctor they prefer (and recommend.) That's always a good start. And remember, Jesus loves you deeply and passionately. He always has and always will. Call upon Him for help. I did. Please take care.

[@nostradamus2231]

I’m trying to figure out if I need medication for my depression and anxiety, but I’m only 20 and I know antidepressants can cause suicidal thoughts in young people

[@rhobot75]

Last comment: I remember being a young adult, or maybe I was in my thirties, anyway, when there was a Front Page News type of study result about making the connection between teens and drugs and depression and which comes first, does smoking cigarettes cause depression , or does depression cause smoking and other drug use. I don't remember what the survey said, but I felt so relieved. And, typing just now I'll go with nicotine causes depression in a young mind. Maybe I don't have substance abuse disorder, Dr. Grande mentions another illness about behavior associated.. Anyway if anyone reads this, thanks! .. I can type like the wind! : ) *\o/*

[@matthewmathers2944]

Can u be diagnosed with MDD let's say a year after the episode but still being 2 weeks long and seek help for it later after experiencing an episode. can you still be diagnosed with MDD

[@kelly4321]

The other criteria listed states that the disturbances can't be explained through schizophrenia and the like, does that mean MDD and schizophrenia can't be comorbid?

[@user-ln6br5md1q]

I think tat would be classified as schitzoaffective.

[@tomershalev6828]

Can you explain what is distimia?

[@deechalakani4929]

Could you do a video on CONVERSION DISORDER?

[@DrGrande]

I have one already, here you go: kzbin.info/www/bejne/f3bCY6GfapahqKM

[@deechalakani4929]

Todd Grande thank you

[@Kay-pr3gr]

great! I need to review this one as well. DO you have videos on other Somatic Disorders?

[@ashleyelizabeth1173]

You're awesome

[@Fnelrbnef]

Watch Melancholia. That's major depressive disorder.

[@dakota-rt8kd]

I have Valid reasons for being depressed and experiencing PTSD. After, everything, which, happened to me, what else is to be expecting. Trust issues are huge and not caring to be social, unless it's absolutely necessary. 😮 hromycin